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The map label for this gene is nuoN

Identifier: 52842974

GI number: 52842974

Start: 3126788

End: 3128260

Strand: Reverse

Name: nuoN

Synonym: lpg2776

Alternate gene names: 52842974

Gene position: 3128260-3126788 (Counterclockwise)

Preceding gene: 52842975

Following gene: 52842973

Centisome position: 92.07

GC content: 37.27

Gene sequence:

>1473_bases
TTGCAATCAAGTTCCTTAGCAAGGTTAAATATGATGACATTACTAGAAAATATCCATGTAGCAATACCAGAAATGATTAT
TTTAATAACCGCGTGTTTGGCGTTGCTTTCTGATTTGTTCTTTCGTCATAAATTAAAATCAATTGCATTTTACATATCTT
GTGTAGGAATTATAGTTTCTGCAGCAGTAAGCTTTGTATTTATAGGAAGCTACAAGTTACTTATATTCAACAAATTATTT
ATAAGTGATGATATAAGTCATTTAATGAAACTGTTTATTGATATCACGGTTTTATTAAGTTTTGTCTATTCCCAAAACTA
TCTGGATGAACGGCAAATGCCTACAGGTGATTACTATGTTCTGGGGCTGTTTTCAACACTAGGTATGATGATTCTTGTTT
CAGCACACTCGCTGTTGTCTCTTTATCTAGGTTTGGAGTTAATGTCATTGCCGCTCTATGCAATGACCGCCATCCGCCGA
ACTGATAGTGATGCATCCGAAGCGGCAATGAAATATTTTGTTATGGGTGCTATTGCTTCTGGTATGCTGTTGTATGGAAT
ATCCCTGGTGTATGGTGCAACAGGAAAACTTGATTTGTTAGATGTTGCTAATGCAGTGGCAGTCAATTGGCAGCAACAAA
ATACTCTTTTTGCGTTTGCAATGGTATTTATACTTGCCGGTGTAGGATTTAAACTGGCTGCTGTCCCTTTCCATATGTGG
GCTCCAGACGTATATCAAGGGGCACCAAGCTCTGTAACACTTTTTATTAGTACAGCACCCAAGATTGCTGCACTGGGGAT
GGCACTGCGATTTTTAACTATTGGCTTAGTCGACATCACCATGCAATGGCAGCAAATTATTTTAGTAATGGCTCTCCTTT
CTACCGGCATAGGTAATTTGTTAGCAGTGATTCAAACCAGAATCAAACGCTTGTTAGCTTATTCTGCAATTTCTCATATA
GGATATGCCTTATTTGGAGTTTTAGCCGCCAGCTCTGCTGGTTATGCCGCAGCACTGTATTATATTTTAGTCTATGCTGT
AATGTCAGCGGCTGCTTTTGGTTTAATTGTATTGATGTCAAATCATGGAATGGAAATTGATAGTATTGATGACTTAAAAG
GCTTGAATAAAAGAAACCCGTGGCTGGCGTTTATGATGCTATTAGTCATGTTCTCAATGGCTGGCGTGCCACCAACGGTT
GGCTTCTTTACAAAATTATTGGTATTGAAGGCATTAGTAGATGTTCATATGACTTGGTTAGCTGTTGTAGGTTTGCTATT
TACGGTTATAGGTGCCTATTATTATTTGCGAATTGTTAAAATCATGTATTTTGATCAACCTGAAAATGAAGAGATAGTAA
GAATTGGTACAGGCAATACCATAGTTTATTCACTTAATTGTCTCTCCTTACTATATTTAGGTATTTTCCCAGGCGCTTTA
ATTGCAGCCTGTATTAATGCATTTGCAAATTAA

Upstream 100 bases:

>100_bases
ATCCCAAACCCATGTTAGAGTTTGTGCATCAAACTGTAAGTCATACTTTGGCACTGGCTGATAAATCTAAACTCTAACAA
AGAACTGCGATAGGCTTACA

Downstream 100 bases:

>100_bases
TTAATAAACTTTAACAAAAGTACTTGCTTAGGGACCCAAGTATCAGTATACTTGCCCTCAGTTGACGCGGGGTGGAGCAG
CCTGGTAGCTCGTCGGGCTC

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MQSSSLARLNMMTLLENIHVAIPEMIILITACLALLSDLFFRHKLKSIAFYISCVGIIVSAAVSFVFIGSYKLLIFNKLF
ISDDISHLMKLFIDITVLLSFVYSQNYLDERQMPTGDYYVLGLFSTLGMMILVSAHSLLSLYLGLELMSLPLYAMTAIRR
TDSDASEAAMKYFVMGAIASGMLLYGISLVYGATGKLDLLDVANAVAVNWQQQNTLFAFAMVFILAGVGFKLAAVPFHMW
APDVYQGAPSSVTLFISTAPKIAALGMALRFLTIGLVDITMQWQQIILVMALLSTGIGNLLAVIQTRIKRLLAYSAISHI
GYALFGVLAASSAGYAAALYYILVYAVMSAAAFGLIVLMSNHGMEIDSIDDLKGLNKRNPWLAFMMLLVMFSMAGVPPTV
GFFTKLLVLKALVDVHMTWLAVVGLLFTVIGAYYYLRIVKIMYFDQPENEEIVRIGTGNTIVYSLNCLSLLYLGIFPGAL
IAACINAFAN

Sequences:

>Translated_490_residues
MQSSSLARLNMMTLLENIHVAIPEMIILITACLALLSDLFFRHKLKSIAFYISCVGIIVSAAVSFVFIGSYKLLIFNKLF
ISDDISHLMKLFIDITVLLSFVYSQNYLDERQMPTGDYYVLGLFSTLGMMILVSAHSLLSLYLGLELMSLPLYAMTAIRR
TDSDASEAAMKYFVMGAIASGMLLYGISLVYGATGKLDLLDVANAVAVNWQQQNTLFAFAMVFILAGVGFKLAAVPFHMW
APDVYQGAPSSVTLFISTAPKIAALGMALRFLTIGLVDITMQWQQIILVMALLSTGIGNLLAVIQTRIKRLLAYSAISHI
GYALFGVLAASSAGYAAALYYILVYAVMSAAAFGLIVLMSNHGMEIDSIDDLKGLNKRNPWLAFMMLLVMFSMAGVPPTV
GFFTKLLVLKALVDVHMTWLAVVGLLFTVIGAYYYLRIVKIMYFDQPENEEIVRIGTGNTIVYSLNCLSLLYLGIFPGAL
IAACINAFAN
>Mature_490_residues
MQSSSLARLNMMTLLENIHVAIPEMIILITACLALLSDLFFRHKLKSIAFYISCVGIIVSAAVSFVFIGSYKLLIFNKLF
ISDDISHLMKLFIDITVLLSFVYSQNYLDERQMPTGDYYVLGLFSTLGMMILVSAHSLLSLYLGLELMSLPLYAMTAIRR
TDSDASEAAMKYFVMGAIASGMLLYGISLVYGATGKLDLLDVANAVAVNWQQQNTLFAFAMVFILAGVGFKLAAVPFHMW
APDVYQGAPSSVTLFISTAPKIAALGMALRFLTIGLVDITMQWQQIILVMALLSTGIGNLLAVIQTRIKRLLAYSAISHI
GYALFGVLAASSAGYAAALYYILVYAVMSAAAFGLIVLMSNHGMEIDSIDDLKGLNKRNPWLAFMMLLVMFSMAGVPPTV
GFFTKLLVLKALVDVHMTWLAVVGLLFTVIGAYYYLRIVKIMYFDQPENEEIVRIGTGNTIVYSLNCLSLLYLGIFPGAL
IAACINAFAN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=307, Percent_Identity=25.0814332247557, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI145693160, Length=477, Percent_Identity=33.3333333333333, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1788614, Length=358, Percent_Identity=28.4916201117318, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788831, Length=346, Percent_Identity=24.5664739884393, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788613, Length=389, Percent_Identity=25.9640102827763, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788827, Length=347, Percent_Identity=23.6311239193084, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI2367154, Length=354, Percent_Identity=24.8587570621469, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1788829, Length=343, Percent_Identity=26.2390670553936, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 53666; Mature: 53666

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA