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The map label for this gene is 52842256

Identifier: 52842256

GI number: 52842256

Start: 2283016

End: 2283897

Strand: Reverse

Name: 52842256

Synonym: lpg2039

Alternate gene names: NA

Gene position: 2283897-2283016 (Counterclockwise)

Preceding gene: 52842257

Following gene: 52842249

Centisome position: 67.22

GC content: 41.04

Gene sequence:

>882_bases
ATGATGTTTTATGATTTTGAAACCACCACTTTTGGCAAGTGGATTTTAGCAGGTGAACACGCGGTAGTAAGGGGACATGA
AGCTTTAGTATTTCCTATCAAGGAAAGGCAATTAACTTTGAAATATAACCCTTCCTCACCGTCCTTGAGCGCAGAATTTC
AAGGCATTAATGGTTCTGATATGCATTTATTATTTTGGAGCGTATTAGAGCGCGGCATGCACTTGTTGGGACGTTCACTG
AATGAATTAGGAGGTCACTTTTATTTGGAAACCAATATTCCTGTTGGGGTTGGCATGGGTGCTTCGGCAGCGCTTTGTGT
TGCCATGAGTCGGTGGTACTGTGCGCAGCAAATGATACAAGATAATCAATGCAATGAATTTGCCAAACAATTAGAACATC
TGTTTCATGGTAAAAGTAGTGGCTTGGATGTAGCTGGTGTAGCGTCAGATACTGGTGTATATTTTAAATCCGGGCTTTGT
ACCCCAGTAAAGCAAACCATTTATCCCTATTGGTATTTATCCTCCTGCAATCAAATCGGCATTACTTCTCATTGTATACA
GCAAGTTGAATATTTATGGAATAAAAATCCAGAACTTGCTCACCAAGTAGATAAGCAAATGGTAGAGGCTGTTCAGGAAG
CAAAAGCTGTTTTGGAAGAAGGGGGGAGTAATGCTTTAAACCGTTTGGCAAAAGCGATAAATAAAGCCGCAGATTGTTTT
TTACAATGGGGTTTGGTTAGTGAGGGCTTGCAACAACATATGAATCATTTGTTTGCTGATGGTGCAATTGCAGTTAAGCC
AACCGGTTCAGGTGGTGGAGGGTTTGTATTAAGCCTTTGGGATAAAATTCCCTCATCCCATACAGAGTTGATTCCGGTCT
AG

Upstream 100 bases:

>100_bases
GTAGTTACTATGGATGCTGGTCCCAATGTTCATTTGCTTTATAGATCAGATCAAACAGATCTCGCACGACAATTTAAATC
GGATCATTTGGTAGGAAACT

Downstream 100 bases:

>100_bases
CTCCTTTCAAGCCTAATCGACAAATTGATAATATACTTCATTTTGCTTAATCATGCCGAGTTCATATCGAGCTTGTTCTT
CAAGAGCCTGATCACCACTT

Product: putative mevalonate kinase

Products: ADP; (R)-5-phosphomevalonate

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MMFYDFETTTFGKWILAGEHAVVRGHEALVFPIKERQLTLKYNPSSPSLSAEFQGINGSDMHLLFWSVLERGMHLLGRSL
NELGGHFYLETNIPVGVGMGASAALCVAMSRWYCAQQMIQDNQCNEFAKQLEHLFHGKSSGLDVAGVASDTGVYFKSGLC
TPVKQTIYPYWYLSSCNQIGITSHCIQQVEYLWNKNPELAHQVDKQMVEAVQEAKAVLEEGGSNALNRLAKAINKAADCF
LQWGLVSEGLQQHMNHLFADGAIAVKPTGSGGGGFVLSLWDKIPSSHTELIPV

Sequences:

>Translated_293_residues
MMFYDFETTTFGKWILAGEHAVVRGHEALVFPIKERQLTLKYNPSSPSLSAEFQGINGSDMHLLFWSVLERGMHLLGRSL
NELGGHFYLETNIPVGVGMGASAALCVAMSRWYCAQQMIQDNQCNEFAKQLEHLFHGKSSGLDVAGVASDTGVYFKSGLC
TPVKQTIYPYWYLSSCNQIGITSHCIQQVEYLWNKNPELAHQVDKQMVEAVQEAKAVLEEGGSNALNRLAKAINKAADCF
LQWGLVSEGLQQHMNHLFADGAIAVKPTGSGGGGFVLSLWDKIPSSHTELIPV
>Mature_293_residues
MMFYDFETTTFGKWILAGEHAVVRGHEALVFPIKERQLTLKYNPSSPSLSAEFQGINGSDMHLLFWSVLERGMHLLGRSL
NELGGHFYLETNIPVGVGMGASAALCVAMSRWYCAQQMIQDNQCNEFAKQLEHLFHGKSSGLDVAGVASDTGVYFKSGLC
TPVKQTIYPYWYLSSCNQIGITSHCIQQVEYLWNKNPELAHQVDKQMVEAVQEAKAVLEEGGSNALNRLAKAINKAADCF
LQWGLVSEGLQQHMNHLFADGAIAVKPTGSGGGGFVLSLWDKIPSSHTELIPV

Specific function: Unknown

COG id: COG1577

COG function: function code I; Mevalonate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.1.36

Molecular weight: Translated: 32269; Mature: 32269

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFYDFETTTFGKWILAGEHAVVRGHEALVFPIKERQLTLKYNPSSPSLSAEFQGINGSD
CEEEECCCCCCCCEEEECCCEEEECCCEEEEEEECCEEEEEECCCCCCCCEEECCCCCCC
MHLLFWSVLERGMHLLGRSLNELGGHFYLETNIPVGVGMGASAALCVAMSRWYCAQQMIQ
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEECCCCCHHHHHHHHHHHHHHHHHHC
DNQCNEFAKQLEHLFHGKSSGLDVAGVASDTGVYFKSGLCTPVKQTIYPYWYLSSCNQIG
CCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCHHHHHHCCCCEECCCCCCC
ITSHCIQQVEYLWNKNPELAHQVDKQMVEAVQEAKAVLEEGGSNALNRLAKAINKAADCF
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LQWGLVSEGLQQHMNHLFADGAIAVKPTGSGGGGFVLSLWDKIPSSHTELIPV
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEHHHHCCCCCCCCCCC
>Mature Secondary Structure
MMFYDFETTTFGKWILAGEHAVVRGHEALVFPIKERQLTLKYNPSSPSLSAEFQGINGSD
CEEEECCCCCCCCEEEECCCEEEECCCEEEEEEECCEEEEEECCCCCCCCEEECCCCCCC
MHLLFWSVLERGMHLLGRSLNELGGHFYLETNIPVGVGMGASAALCVAMSRWYCAQQMIQ
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEECCCCCHHHHHHHHHHHHHHHHHHC
DNQCNEFAKQLEHLFHGKSSGLDVAGVASDTGVYFKSGLCTPVKQTIYPYWYLSSCNQIG
CCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCHHHHHHCCCCEECCCCCCC
ITSHCIQQVEYLWNKNPELAHQVDKQMVEAVQEAKAVLEEGGSNALNRLAKAINKAADCF
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
LQWGLVSEGLQQHMNHLFADGAIAVKPTGSGGGGFVLSLWDKIPSSHTELIPV
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; (R)-mevalonate

Specific reaction: ATP + (R)-mevalonate = ADP + (R)-5-phosphomevalonate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA