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The map label for this gene is suhB

Identifier: 52841975

GI number: 52841975

Start: 1948527

End: 1949312

Strand: Direct

Name: suhB

Synonym: lpg1748

Alternate gene names: 52841975

Gene position: 1948527-1949312 (Clockwise)

Preceding gene: 52841969

Following gene: 52841977

Centisome position: 57.35

GC content: 43.13

Gene sequence:

>786_bases
ATGGAACCACTTTTAAATATTGCTGTCAATGCTGCGCGACAGGCTGGTGAAATCATTAATCGTTATGTAGAGCAAGTTGA
TCGTTTAAAAATAACTCCCAAAAACAGCCATGAATATTTTAGTGAAGTGGACATTAAAGCGGAGCAAGTTATCATTAATA
CGATACATAAAGCCTACCCAGAGCATGGAATTCTTGCCGAAGAAAGCGGTATTCAGCAAAGCGATAGTGATACAGTCTGG
ATCATTGATCCATTGGATGGCACCTCAAATTATCTTCATGGATTCCCTTTTTATTCTGTATCCATAGCCCTGAAAATTAA
AAATCGTCTGGAGCATGGTGTTATTTACGATCCCCTGCGACATGAGTGTTTTGCTGCAAGCAGAGGACGCGGAGCAAGGC
TAAACGATAGAAGAATCCGTGTGTCCAAGCAAACTCAACTCAATGCTTCTCTGTTAGGCACAGGTTTTCATTTTCGAGAT
GCAACTCTTGCACAGCGATATTTACCAACCTTTGAAGCATTGATTGGAAAATGTGCTGGAGTTAGAAGAACAGGTTCTGC
TGCTCTCGACTTGGCTTATGTTGCAAGCGGTCGTCTGGATGGCTTCTGGGAGTTTGGGTTGCGCCCATGGGATATTGCTG
CGGGAGCCCTGCTGGTTCGAGAGGCTGGGGGATTAATAAGTGATGTCCAGGGTGGAGAAGATTTCCTGAATTATGGCGAC
GTAGTAGCAGGAACTCCTAAAGTATTTAAGTCACTTTTGCAAACCATATCACCCGTTTTAAAATAA

Upstream 100 bases:

>100_bases
ATACAATAGATAACTATATCATAGGATTTATTAATTGAACTTCTCTTTGTTTAAAAAAAATGTGTTAGAATTGCTGATTT
TATAGCTAAAGAGTATATCC

Downstream 100 bases:

>100_bases
GTTGTCAATTTAAGCTCATTTAAGACGTTCATTTAGGCTTATCGATTTTAAATTATTTTCGAATATCCGCTCTCTCGAAG
CTGAGAAAGCGGATAAATAC

Product: inositol-1-monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MEPLLNIAVNAARQAGEIINRYVEQVDRLKITPKNSHEYFSEVDIKAEQVIINTIHKAYPEHGILAEESGIQQSDSDTVW
IIDPLDGTSNYLHGFPFYSVSIALKIKNRLEHGVIYDPLRHECFAASRGRGARLNDRRIRVSKQTQLNASLLGTGFHFRD
ATLAQRYLPTFEALIGKCAGVRRTGSAALDLAYVASGRLDGFWEFGLRPWDIAAGALLVREAGGLISDVQGGEDFLNYGD
VVAGTPKVFKSLLQTISPVLK

Sequences:

>Translated_261_residues
MEPLLNIAVNAARQAGEIINRYVEQVDRLKITPKNSHEYFSEVDIKAEQVIINTIHKAYPEHGILAEESGIQQSDSDTVW
IIDPLDGTSNYLHGFPFYSVSIALKIKNRLEHGVIYDPLRHECFAASRGRGARLNDRRIRVSKQTQLNASLLGTGFHFRD
ATLAQRYLPTFEALIGKCAGVRRTGSAALDLAYVASGRLDGFWEFGLRPWDIAAGALLVREAGGLISDVQGGEDFLNYGD
VVAGTPKVFKSLLQTISPVLK
>Mature_261_residues
MEPLLNIAVNAARQAGEIINRYVEQVDRLKITPKNSHEYFSEVDIKAEQVIINTIHKAYPEHGILAEESGIQQSDSDTVW
IIDPLDGTSNYLHGFPFYSVSIALKIKNRLEHGVIYDPLRHECFAASRGRGARLNDRRIRVSKQTQLNASLLGTGFHFRD
ATLAQRYLPTFEALIGKCAGVRRTGSAALDLAYVASGRLDGFWEFGLRPWDIAAGALLVREAGGLISDVQGGEDFLNYGD
VVAGTPKVFKSLLQTISPVLK

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=266, Percent_Identity=36.0902255639098, Blast_Score=161, Evalue=4e-40,
Organism=Homo sapiens, GI5031789, Length=255, Percent_Identity=32.9411764705882, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI221625487, Length=255, Percent_Identity=32.9411764705882, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI221625507, Length=148, Percent_Identity=33.7837837837838, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI1788882, Length=257, Percent_Identity=51.3618677042802, Blast_Score=280, Evalue=9e-77,
Organism=Caenorhabditis elegans, GI193202572, Length=265, Percent_Identity=28.3018867924528, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI193202570, Length=269, Percent_Identity=28.996282527881, Blast_Score=133, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6320493, Length=211, Percent_Identity=32.7014218009479, Blast_Score=123, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6321836, Length=241, Percent_Identity=30.2904564315353, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21357329, Length=267, Percent_Identity=37.4531835205993, Blast_Score=177, Evalue=8e-45,
Organism=Drosophila melanogaster, GI21357303, Length=210, Percent_Identity=36.6666666666667, Blast_Score=147, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24664922, Length=225, Percent_Identity=34.6666666666667, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24664926, Length=226, Percent_Identity=33.1858407079646, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI21357957, Length=263, Percent_Identity=30.7984790874525, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24664918, Length=255, Percent_Identity=31.7647058823529, Blast_Score=110, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 28838; Mature: 28838

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPLLNIAVNAARQAGEIINRYVEQVDRLKITPKNSHEYFSEVDIKAEQVIINTIHKAYP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHCCCHHHHHHHHHHHHHCC
EHGILAEESGIQQSDSDTVWIIDPLDGTSNYLHGFPFYSVSIALKIKNRLEHGVIYDPLR
CCCCEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEEHHHHCCCCEECCHH
HECFAASRGRGARLNDRRIRVSKQTQLNASLLGTGFHFRDATLAQRYLPTFEALIGKCAG
HHHHHHCCCCCCCCCCCEEEEEHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHC
VRRTGSAALDLAYVASGRLDGFWEFGLRPWDIAAGALLVREAGGLISDVQGGEDFLNYGD
CCCCCCHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHCCCC
VVAGTPKVFKSLLQTISPVLK
CCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEPLLNIAVNAARQAGEIINRYVEQVDRLKITPKNSHEYFSEVDIKAEQVIINTIHKAYP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHCCCHHHHHHHHHHHHHCC
EHGILAEESGIQQSDSDTVWIIDPLDGTSNYLHGFPFYSVSIALKIKNRLEHGVIYDPLR
CCCCEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEEHHHHCCCCEECCHH
HECFAASRGRGARLNDRRIRVSKQTQLNASLLGTGFHFRDATLAQRYLPTFEALIGKCAG
HHHHHHCCCCCCCCCCCEEEEEHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHC
VRRTGSAALDLAYVASGRLDGFWEFGLRPWDIAAGALLVREAGGLISDVQGGEDFLNYGD
CCCCCCHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHCCCC
VVAGTPKVFKSLLQTISPVLK
CCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]