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The map label for this gene is gatA

Identifier: 52841963

GI number: 52841963

Start: 1936655

End: 1938106

Strand: Direct

Name: gatA

Synonym: lpg1736

Alternate gene names: 52841963

Gene position: 1936655-1938106 (Clockwise)

Preceding gene: 52841962

Following gene: 52841964

Centisome position: 57.0

GC content: 40.63

Gene sequence:

>1452_bases
ATGGAACATTACTCACTGGCTCAATTATCAAAGGCTCTTCATAATCGAGAATTTTCAAGTGTTGAATTAACACAACACTG
TATTAACAAAATTCAAAGCAATAAAGACTTGAATGCATTCATCAGCCTTGATGAAGACCAGGCTCTTAAAGAAGCGCAAT
CGGCTGATTTGGTACTAAAAAGTGGGGAGGGAAAGCCACTGACTGGTATCCCCATGGCTCTCAAGGATTTGTTTTGTACA
AAGCGATTAAATACAACTTGTGCTTCAAAAATGCTGGCTAATTTTCAAGCCCCATATGATGCCACTATCGTCACAAAATT
TAAACAAAATGGCGCAATTATTATTGGAAAAACCAATATGGATGAGTTTGCCATGGGATCCTCTAATGAAAACAGTTACT
TCGGTTCGGTAAAAAACCCGTGGGATAGAGAAAGAGTGTCAGGTGGATCATCAGGCGGTTCTGCAGCAGCGGTTGCTGGA
AATCTGGTACCTTTTGCAATTGGCTCTGACACCGGTGGATCAATTCGTCAGCCAGCAGCCTTTTGCGGGATTAGCGGGAT
AAAACCCACCTATGGATTAGTCTCTCGATACGGAATGGTCGCCTTTGCCTCAAGCCTTGATCAAGCGGGACCATTTGCGA
AATCAGCTGAAGATCTGGCCATGATACTTCACTGTATGGCGGGGTTTGATAGTAAAGATTCCACGTCAGTTGATAGAGTT
ATACCTGATTATTCAGCAGAAATTAAAAACCCAGTAGACAAAATACGCATAGGACTTCCTTCTTGCTTTTTTCAACCTCA
AGTCGAAAAAGGTATCCAGGATGCCATACATGATGCTGTGAAATTATTTGAGAATCTAGGGGCTGAAATAATTGAAATCG
ACTTGAAACTTCAGCCACTTTGGGTGCCATGTTACTATGTTATAGCTTGCGCAGAAGCTTCATCAAATCTTTCGCGTTAT
GATGGCATAAGATTTGGCCACCGAAGCAAATCCGCATCAACCTTAATTGAATTAATCACTAACTCTCGAAGTGAAGGTTT
TGGTAACGAGGTAAAACGTCGAATTCTAACTGGAACTCATGTGCTCTCATCCGGTTTTTTTGATGCCTATTATTTGCATG
CACAAAAAGTGAGGCGTTTGATTCGAGATGAATTAATTACAACTTTAAATTCAGTAGATGTTATCCTTGGGCCAACAACT
CCTACCACCGCTTTTAAATTGGGTGAAAAAATAGATGATCCCATACAAAATTATTTGGCAGATGTATTTACTGTAGCAGC
CAATCTTGCAGGCCTACCAGCTGTTTCTATACCAACTGGTTTTGAAAATAAACTACCAATTGGTTTGCAATTAATGAGCA
AGCACTTTAGTGAAAACCGCTTGCTTGCAATCGCACATCATTATCAGCAACACACCAACTGGCATTTAGCCAATCCTAAC
AAGCAAAGGTGA

Upstream 100 bases:

>100_bases
TAACTGAAGCGGAATGTCTTGCTGAATTAGAAGCCATGGCGCCATTATTTGAGGATAACTTATATTTGGTTCCCAAGGTG
ATATCATCGGATAAATAATA

Downstream 100 bases:

>100_bases
TATATGGAATGGGATACCGTCATTGGTCTTGAGGTACATGCTCAATTAAAAACCAAATCAAAATTATTTTCAGGAGCATC
TACTGCTTTTGGTGCCACCC

Product: aspartyl/glutamyl-tRNA amidotransferase subunit A

Products: NA

Alternate protein names: Glu-ADT subunit A [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MEHYSLAQLSKALHNREFSSVELTQHCINKIQSNKDLNAFISLDEDQALKEAQSADLVLKSGEGKPLTGIPMALKDLFCT
KRLNTTCASKMLANFQAPYDATIVTKFKQNGAIIIGKTNMDEFAMGSSNENSYFGSVKNPWDRERVSGGSSGGSAAAVAG
NLVPFAIGSDTGGSIRQPAAFCGISGIKPTYGLVSRYGMVAFASSLDQAGPFAKSAEDLAMILHCMAGFDSKDSTSVDRV
IPDYSAEIKNPVDKIRIGLPSCFFQPQVEKGIQDAIHDAVKLFENLGAEIIEIDLKLQPLWVPCYYVIACAEASSNLSRY
DGIRFGHRSKSASTLIELITNSRSEGFGNEVKRRILTGTHVLSSGFFDAYYLHAQKVRRLIRDELITTLNSVDVILGPTT
PTTAFKLGEKIDDPIQNYLADVFTVAANLAGLPAVSIPTGFENKLPIGLQLMSKHFSENRLLAIAHHYQQHTNWHLANPN
KQR

Sequences:

>Translated_483_residues
MEHYSLAQLSKALHNREFSSVELTQHCINKIQSNKDLNAFISLDEDQALKEAQSADLVLKSGEGKPLTGIPMALKDLFCT
KRLNTTCASKMLANFQAPYDATIVTKFKQNGAIIIGKTNMDEFAMGSSNENSYFGSVKNPWDRERVSGGSSGGSAAAVAG
NLVPFAIGSDTGGSIRQPAAFCGISGIKPTYGLVSRYGMVAFASSLDQAGPFAKSAEDLAMILHCMAGFDSKDSTSVDRV
IPDYSAEIKNPVDKIRIGLPSCFFQPQVEKGIQDAIHDAVKLFENLGAEIIEIDLKLQPLWVPCYYVIACAEASSNLSRY
DGIRFGHRSKSASTLIELITNSRSEGFGNEVKRRILTGTHVLSSGFFDAYYLHAQKVRRLIRDELITTLNSVDVILGPTT
PTTAFKLGEKIDDPIQNYLADVFTVAANLAGLPAVSIPTGFENKLPIGLQLMSKHFSENRLLAIAHHYQQHTNWHLANPN
KQR
>Mature_483_residues
MEHYSLAQLSKALHNREFSSVELTQHCINKIQSNKDLNAFISLDEDQALKEAQSADLVLKSGEGKPLTGIPMALKDLFCT
KRLNTTCASKMLANFQAPYDATIVTKFKQNGAIIIGKTNMDEFAMGSSNENSYFGSVKNPWDRERVSGGSSGGSAAAVAG
NLVPFAIGSDTGGSIRQPAAFCGISGIKPTYGLVSRYGMVAFASSLDQAGPFAKSAEDLAMILHCMAGFDSKDSTSVDRV
IPDYSAEIKNPVDKIRIGLPSCFFQPQVEKGIQDAIHDAVKLFENLGAEIIEIDLKLQPLWVPCYYVIACAEASSNLSRY
DGIRFGHRSKSASTLIELITNSRSEGFGNEVKRRILTGTHVLSSGFFDAYYLHAQKVRRLIRDELITTLNSVDVILGPTT
PTTAFKLGEKIDDPIQNYLADVFTVAANLAGLPAVSIPTGFENKLPIGLQLMSKHFSENRLLAIAHHYQQHTNWHLANPN
KQR

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=497, Percent_Identity=40.4426559356137, Blast_Score=342, Evalue=5e-94,
Organism=Homo sapiens, GI195972892, Length=494, Percent_Identity=28.3400809716599, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI166795287, Length=255, Percent_Identity=28.2352941176471, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17543272, Length=451, Percent_Identity=39.689578713969, Blast_Score=290, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI17537465, Length=507, Percent_Identity=26.0355029585799, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17556264, Length=302, Percent_Identity=26.8211920529801, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71990152, Length=321, Percent_Identity=25.2336448598131, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17538252, Length=318, Percent_Identity=27.6729559748428, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17556276, Length=187, Percent_Identity=31.5508021390374, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17556278, Length=187, Percent_Identity=31.5508021390374, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538254, Length=286, Percent_Identity=25.5244755244755, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323950, Length=426, Percent_Identity=35.9154929577465, Blast_Score=243, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6319685, Length=450, Percent_Identity=32.6666666666667, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320448, Length=531, Percent_Identity=22.5988700564972, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24648113, Length=482, Percent_Identity=39.4190871369295, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI24644968, Length=494, Percent_Identity=28.3400809716599, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24652985, Length=500, Percent_Identity=28.8, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI19922090, Length=500, Percent_Identity=28.8, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24652981, Length=500, Percent_Identity=28.8, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24652983, Length=500, Percent_Identity=28.8, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI161078093, Length=502, Percent_Identity=29.4820717131474, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI45550774, Length=514, Percent_Identity=26.4591439688716, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24648435, Length=515, Percent_Identity=26.4077669902913, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24648437, Length=515, Percent_Identity=26.4077669902913, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21356731, Length=506, Percent_Identity=25.6916996047431, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24648441, Length=451, Percent_Identity=26.1640798226164, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24648439, Length=451, Percent_Identity=26.1640798226164, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: 6.3.5.-

Molecular weight: Translated: 52715; Mature: 52715

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHYSLAQLSKALHNREFSSVELTQHCINKIQSNKDLNAFISLDEDQALKEAQSADLVLK
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCEEEE
SGEGKPLTGIPMALKDLFCTKRLNTTCASKMLANFQAPYDATIVTKFKQNGAIIIGKTNM
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCC
DEFAMGSSNENSYFGSVKNPWDRERVSGGSSGGSAAAVAGNLVPFAIGSDTGGSIRQPAA
HHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCHH
FCGISGIKPTYGLVSRYGMVAFASSLDQAGPFAKSAEDLAMILHCMAGFDSKDSTSVDRV
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHH
IPDYSAEIKNPVDKIRIGLPSCFFQPQVEKGIQDAIHDAVKLFENLGAEIIEIDLKLQPL
CCCCHHHHCCCHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEE
WVPCYYVIACAEASSNLSRYDGIRFGHRSKSASTLIELITNSRSEGFGNEVKRRILTGTH
EEHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VLSSGFFDAYYLHAQKVRRLIRDELITTLNSVDVILGPTTPTTAFKLGEKIDDPIQNYLA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHH
DVFTVAANLAGLPAVSIPTGFENKLPIGLQLMSKHFSENRLLAIAHHYQQHTNWHLANPN
HHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCEEEHHHHHHHCCCEEECCCC
KQR
CCC
>Mature Secondary Structure
MEHYSLAQLSKALHNREFSSVELTQHCINKIQSNKDLNAFISLDEDQALKEAQSADLVLK
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCEEEE
SGEGKPLTGIPMALKDLFCTKRLNTTCASKMLANFQAPYDATIVTKFKQNGAIIIGKTNM
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCC
DEFAMGSSNENSYFGSVKNPWDRERVSGGSSGGSAAAVAGNLVPFAIGSDTGGSIRQPAA
HHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCHH
FCGISGIKPTYGLVSRYGMVAFASSLDQAGPFAKSAEDLAMILHCMAGFDSKDSTSVDRV
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHH
IPDYSAEIKNPVDKIRIGLPSCFFQPQVEKGIQDAIHDAVKLFENLGAEIIEIDLKLQPL
CCCCHHHHCCCHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEE
WVPCYYVIACAEASSNLSRYDGIRFGHRSKSASTLIELITNSRSEGFGNEVKRRILTGTH
EEHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
VLSSGFFDAYYLHAQKVRRLIRDELITTLNSVDVILGPTTPTTAFKLGEKIDDPIQNYLA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHH
DVFTVAANLAGLPAVSIPTGFENKLPIGLQLMSKHFSENRLLAIAHHYQQHTNWHLANPN
HHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCEEEHHHHHHHCCCEEECCCC
KQR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA