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The map label for this gene is gatB

Identifier: 52841964

GI number: 52841964

Start: 1938110

End: 1939543

Strand: Direct

Name: gatB

Synonym: lpg1737

Alternate gene names: 52841964

Gene position: 1938110-1939543 (Clockwise)

Preceding gene: 52841963

Following gene: 52841965

Centisome position: 57.04

GC content: 37.73

Gene sequence:

>1434_bases
ATGGAATGGGATACCGTCATTGGTCTTGAGGTACATGCTCAATTAAAAACCAAATCAAAATTATTTTCAGGAGCATCTAC
TGCTTTTGGTGCCACCCCTAACTCGCAAACGAGTTTTATCGATGCTGGTTTGCCTGGTGTTCTCCCTGTGTTAAATGAAC
AAGCCATCATAATGGCTATCCAATTTGGTTTGGCAATTCATGGAACCATTAATGATTTGTCTGTTTTTGAACGCAAAAAT
TATTTTTATCCTGACTTACCCAAAGGCTATCAAATCAGTCAGTATCAAAAACCCATTGTTACTAATGGCTATTTAAATAT
ACAGCTTGGTAATAACCTGGAAAAAACAGTCCATATTGCACGCGCTCATTTAGAAGAAGATGCTGGCAAATCCCTACACG
ATGCCCATACTGATTACACCGGGATCGACCTCAACAGAGCAGGTACCCCACTATTGGAAATAGTCACAACCCCTTGCCTG
TACTCGGCTGAAGAGGCGATTAATTATTTAAAAACGCTGCATCAATTAGTGAGATTCCTTGGAATATGCGATGGCAATAT
GCAAGAAGGTTCTTTTCGGTGTGACGTCAATCTGTCTATAAAACCTAAAGGCAGCTCAGTTTTAGGCACACGAACAGAAC
TTAAAAATCTGAATTCATTTCGTTTTATTGAAAAAGCCATTGCTTTTGAACAGGCAAGACACCAAGATATATTGGAAAGC
GGTCTGTCAGTCATCCAGGAGACTCGCCTTTACAATCCTGACAATAACACAACTCAGGCGATGAGAGGCAAGGAAAATGA
AAATGATTACCGTTATTTTCCTGATCCTGATTTATTACCAATTCATATTGACAAAGAACAAGTTGAAGAGATTAAAAATA
ACCTGCCGGACTTGCCTGAAGCAATTTCCAAAGAATTAAAAAACACTCCGTCCCTAAATGATGAAGACATTAATTTCATA
TTATCATCACCGGACACTTATCAATATTACAAAAAAATTAAATCCCTTTGTCCGGCTGCTGATAAAACAATTATCAACTG
GTTAAAAGGCCAATATGCCGCCTTTCTTAATGAACACAACCTAACCTTTGAAACACCACCAATTTCAGCTAAAACCATGG
CTGCTTTTCTTAGCAAAATTCATGAGAAAAAAATCTCTTCTAGTATTGCTAAAAATATTTTCAGTATGCTTTGCACAGGT
GAAAAAGATATCGATGCGATTATTGAACGCGAAGGCTACCAGCAACAGAATGACAACTCGGCACTGGAAGAAATAGTTGA
GCAAATAATCAAACAATATCCCGAACAAGTTACAGAATACAAAGCCGGTAAAGAGAAATTATTAGCTTTTTTTATCGGGC
AAGCGATGAAACAAACTAAAGGGAAAGCAAATCCCGAGCAAATCAATCTGTTATTAAAAAAACATCTTGGATGA

Upstream 100 bases:

>100_bases
GAGCAAGCACTTTAGTGAAAACCGCTTGCTTGCAATCGCACATCATTATCAGCAACACACCAACTGGCATTTAGCCAATC
CTAACAAGCAAAGGTGATAT

Downstream 100 bases:

>100_bases
TGCAATATTTTTATAATTCACAATGCTCATTTATGGCCTTGTTGATTGATTGCCAGCTATTATCATCTTTTTGTCAGAAG
GTATAATGCAAGCATTCAAT

Product: aspartyl/glutamyl-tRNA amidotransferase subunit B

Products: NA

Alternate protein names: Asp/Glu-ADT subunit B [H]

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MEWDTVIGLEVHAQLKTKSKLFSGASTAFGATPNSQTSFIDAGLPGVLPVLNEQAIIMAIQFGLAIHGTINDLSVFERKN
YFYPDLPKGYQISQYQKPIVTNGYLNIQLGNNLEKTVHIARAHLEEDAGKSLHDAHTDYTGIDLNRAGTPLLEIVTTPCL
YSAEEAINYLKTLHQLVRFLGICDGNMQEGSFRCDVNLSIKPKGSSVLGTRTELKNLNSFRFIEKAIAFEQARHQDILES
GLSVIQETRLYNPDNNTTQAMRGKENENDYRYFPDPDLLPIHIDKEQVEEIKNNLPDLPEAISKELKNTPSLNDEDINFI
LSSPDTYQYYKKIKSLCPAADKTIINWLKGQYAAFLNEHNLTFETPPISAKTMAAFLSKIHEKKISSSIAKNIFSMLCTG
EKDIDAIIEREGYQQQNDNSALEEIVEQIIKQYPEQVTEYKAGKEKLLAFFIGQAMKQTKGKANPEQINLLLKKHLG

Sequences:

>Translated_477_residues
MEWDTVIGLEVHAQLKTKSKLFSGASTAFGATPNSQTSFIDAGLPGVLPVLNEQAIIMAIQFGLAIHGTINDLSVFERKN
YFYPDLPKGYQISQYQKPIVTNGYLNIQLGNNLEKTVHIARAHLEEDAGKSLHDAHTDYTGIDLNRAGTPLLEIVTTPCL
YSAEEAINYLKTLHQLVRFLGICDGNMQEGSFRCDVNLSIKPKGSSVLGTRTELKNLNSFRFIEKAIAFEQARHQDILES
GLSVIQETRLYNPDNNTTQAMRGKENENDYRYFPDPDLLPIHIDKEQVEEIKNNLPDLPEAISKELKNTPSLNDEDINFI
LSSPDTYQYYKKIKSLCPAADKTIINWLKGQYAAFLNEHNLTFETPPISAKTMAAFLSKIHEKKISSSIAKNIFSMLCTG
EKDIDAIIEREGYQQQNDNSALEEIVEQIIKQYPEQVTEYKAGKEKLLAFFIGQAMKQTKGKANPEQINLLLKKHLG
>Mature_477_residues
MEWDTVIGLEVHAQLKTKSKLFSGASTAFGATPNSQTSFIDAGLPGVLPVLNEQAIIMAIQFGLAIHGTINDLSVFERKN
YFYPDLPKGYQISQYQKPIVTNGYLNIQLGNNLEKTVHIARAHLEEDAGKSLHDAHTDYTGIDLNRAGTPLLEIVTTPCL
YSAEEAINYLKTLHQLVRFLGICDGNMQEGSFRCDVNLSIKPKGSSVLGTRTELKNLNSFRFIEKAIAFEQARHQDILES
GLSVIQETRLYNPDNNTTQAMRGKENENDYRYFPDPDLLPIHIDKEQVEEIKNNLPDLPEAISKELKNTPSLNDEDINFI
LSSPDTYQYYKKIKSLCPAADKTIINWLKGQYAAFLNEHNLTFETPPISAKTMAAFLSKIHEKKISSSIAKNIFSMLCTG
EKDIDAIIEREGYQQQNDNSALEEIVEQIIKQYPEQVTEYKAGKEKLLAFFIGQAMKQTKGKANPEQINLLLKKHLG

Specific function: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction take

COG id: COG0064

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gatB/gatE family. GatB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758894, Length=495, Percent_Identity=36.969696969697, Blast_Score=316, Evalue=4e-86,
Organism=Caenorhabditis elegans, GI115534094, Length=355, Percent_Identity=36.9014084507042, Blast_Score=221, Evalue=6e-58,
Organism=Saccharomyces cerevisiae, GI6319391, Length=510, Percent_Identity=32.156862745098, Blast_Score=217, Evalue=3e-57,
Organism=Drosophila melanogaster, GI45550808, Length=491, Percent_Identity=35.6415478615071, Blast_Score=298, Evalue=5e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017959
- InterPro:   IPR018027
- InterPro:   IPR003789
- InterPro:   IPR004413
- InterPro:   IPR006075
- InterPro:   IPR017958 [H]

Pfam domain/function: PF02934 GatB_N; PF02637 GatB_Yqey [H]

EC number: 6.3.5.-

Molecular weight: Translated: 53619; Mature: 53619

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS01234 GATB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWDTVIGLEVHAQLKTKSKLFSGASTAFGATPNSQTSFIDAGLPGVLPVLNEQAIIMAI
CCCCEEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCHHHHHCCCEEEEEE
QFGLAIHGTINDLSVFERKNYFYPDLPKGYQISQYQKPIVTNGYLNIQLGNNLEKTVHIA
ECCEEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHCCCCEECCEEEEEECCCHHHHHHHH
RAHLEEDAGKSLHDAHTDYTGIDLNRAGTPLLEIVTTPCLYSAEEAINYLKTLHQLVRFL
HHHHHHHCCCCHHHCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GICDGNMQEGSFRCDVNLSIKPKGSSVLGTRTELKNLNSFRFIEKAIAFEQARHQDILES
HCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GLSVIQETRLYNPDNNTTQAMRGKENENDYRYFPDPDLLPIHIDKEQVEEIKNNLPDLPE
HHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCCHHH
AISKELKNTPSLNDEDINFILSSPDTYQYYKKIKSLCPAADKTIINWLKGQYAAFLNEHN
HHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
LTFETPPISAKTMAAFLSKIHEKKISSSIAKNIFSMLCTGEKDIDAIIEREGYQQQNDNS
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCH
ALEEIVEQIIKQYPEQVTEYKAGKEKLLAFFIGQAMKQTKGKANPEQINLLLKKHLG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MEWDTVIGLEVHAQLKTKSKLFSGASTAFGATPNSQTSFIDAGLPGVLPVLNEQAIIMAI
CCCCEEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCHHHHHCCCEEEEEE
QFGLAIHGTINDLSVFERKNYFYPDLPKGYQISQYQKPIVTNGYLNIQLGNNLEKTVHIA
ECCEEEECCCHHHHHHHHCCCCCCCCCCCCCCHHHCCCCEECCEEEEEECCCHHHHHHHH
RAHLEEDAGKSLHDAHTDYTGIDLNRAGTPLLEIVTTPCLYSAEEAINYLKTLHQLVRFL
HHHHHHHCCCCHHHCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GICDGNMQEGSFRCDVNLSIKPKGSSVLGTRTELKNLNSFRFIEKAIAFEQARHQDILES
HCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GLSVIQETRLYNPDNNTTQAMRGKENENDYRYFPDPDLLPIHIDKEQVEEIKNNLPDLPE
HHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCCHHH
AISKELKNTPSLNDEDINFILSSPDTYQYYKKIKSLCPAADKTIINWLKGQYAAFLNEHN
HHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
LTFETPPISAKTMAAFLSKIHEKKISSSIAKNIFSMLCTGEKDIDAIIEREGYQQQNDNS
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCH
ALEEIVEQIIKQYPEQVTEYKAGKEKLLAFFIGQAMKQTKGKANPEQINLLLKKHLG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA