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The map label for this gene is add

Identifier: 52840817

GI number: 52840817

Start: 615519

End: 616499

Strand: Reverse

Name: add

Synonym: lpg0580

Alternate gene names: 52840817

Gene position: 616499-615519 (Counterclockwise)

Preceding gene: 52840820

Following gene: 52840815

Centisome position: 18.14

GC content: 37.41

Gene sequence:

>981_bases
ATGAATTTAAAAAAGGCAGAATTACACGTACATCTAGAAGGAACTATTTCCCCAGAACTCGCCAAAAAACTAGCAAAAAG
AAATCAATTAACTCTCCCTAATGGTCTTATTGCACCAGATGAAAAAAGTTACTTATCAAAAGACTTTCTCGATTTTCTTA
AGGTTTATGATACGCTGGCATCCGTAATTAAAAATCCACAAGATTATTATGATATTACCTTTGATTATCTTAAATCGAAC
GCTCAAGAACATGCTATCTACATTGAAATGATGTACTCTCCGGACCATGCCGAGCAATCCAGTGGAATTCCTTCAAAAGA
GCATTTAGCAGCAATTCAACAGGCTATTGATGATGCTAAAAGTCAATTTGATATTGTTGGACGTATTATTATCACTGCAG
TACGCCATTTTGGCGTAGAAGCATGCGAACGCGTCGCAAAACAGGCTTCTATAGATAAATTTCCTTGTGTAACAGGATTT
GGATTAGGAGGAGATGAAGCAAAATTTCCTCCTCAATTGTTTACCAAAGCTTATCAGATAGCAGCAGACTCCGGATTGGA
ATGCACCGTTCATGCCGGCGAATTTGATTCAGCCAAAGGAATGGAAGAAGCAATGAAAACTCTGCCAATTAAAAGAATTG
GGCATGGGGTTCGAGTGATTGACTCACCTGACATTATGGCCATGGTTAAAGACCAGGGTATTGCATTGGAAGTGTGCCCA
ACCAGTAACATATTTTTGGGATTATTCAAAGACATGAATAGCCACCCTTTTCCAAAGCTTTATGAAGCAGGGATTAAAGT
CAGTATTAATTCCGATGATCCTCCTTTTATGAGCACTACACTTGCTCAAGAATACAAAAGAGTTCAAAAAGCTTATGGCT
ATAACAATGACACAATGAATAATATTACGCGTATGGCTATTGAAGCTGCTTTTGTTGATGAAAAAACCCGGAAAGAACTT
TTAACAAAATTAGAACAATAA

Upstream 100 bases:

>100_bases
CATACTCAATCCAAAATAACTTTATTTAAAAAATATATTTTATCGTTTTTTTATCTAAGTTACCATTAATCTTCTTTCAA
GTAAGATAATAGGCTATATC

Downstream 100 bases:

>100_bases
TCTCAGTCTTATATTCCTGTTGTCAGTACTAAGTCCCTGCTGACTTGAGGCGATAACGATACTGTTATATTTTTACAGGT
TGGTGTTGATACATGGCTTA

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MNLKKAELHVHLEGTISPELAKKLAKRNQLTLPNGLIAPDEKSYLSKDFLDFLKVYDTLASVIKNPQDYYDITFDYLKSN
AQEHAIYIEMMYSPDHAEQSSGIPSKEHLAAIQQAIDDAKSQFDIVGRIIITAVRHFGVEACERVAKQASIDKFPCVTGF
GLGGDEAKFPPQLFTKAYQIAADSGLECTVHAGEFDSAKGMEEAMKTLPIKRIGHGVRVIDSPDIMAMVKDQGIALEVCP
TSNIFLGLFKDMNSHPFPKLYEAGIKVSINSDDPPFMSTTLAQEYKRVQKAYGYNNDTMNNITRMAIEAAFVDEKTRKEL
LTKLEQ

Sequences:

>Translated_326_residues
MNLKKAELHVHLEGTISPELAKKLAKRNQLTLPNGLIAPDEKSYLSKDFLDFLKVYDTLASVIKNPQDYYDITFDYLKSN
AQEHAIYIEMMYSPDHAEQSSGIPSKEHLAAIQQAIDDAKSQFDIVGRIIITAVRHFGVEACERVAKQASIDKFPCVTGF
GLGGDEAKFPPQLFTKAYQIAADSGLECTVHAGEFDSAKGMEEAMKTLPIKRIGHGVRVIDSPDIMAMVKDQGIALEVCP
TSNIFLGLFKDMNSHPFPKLYEAGIKVSINSDDPPFMSTTLAQEYKRVQKAYGYNNDTMNNITRMAIEAAFVDEKTRKEL
LTKLEQ
>Mature_326_residues
MNLKKAELHVHLEGTISPELAKKLAKRNQLTLPNGLIAPDEKSYLSKDFLDFLKVYDTLASVIKNPQDYYDITFDYLKSN
AQEHAIYIEMMYSPDHAEQSSGIPSKEHLAAIQQAIDDAKSQFDIVGRIIITAVRHFGVEACERVAKQASIDKFPCVTGF
GLGGDEAKFPPQLFTKAYQIAADSGLECTVHAGEFDSAKGMEEAMKTLPIKRIGHGVRVIDSPDIMAMVKDQGIALEVCP
TSNIFLGLFKDMNSHPFPKLYEAGIKVSINSDDPPFMSTTLAQEYKRVQKAYGYNNDTMNNITRMAIEAAFVDEKTRKEL
LTKLEQ

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=348, Percent_Identity=27.8735632183908, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI226693318, Length=331, Percent_Identity=25.6797583081571, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI61175224, Length=220, Percent_Identity=25.9090909090909, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1787910, Length=327, Percent_Identity=27.217125382263, Blast_Score=147, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI32565969, Length=349, Percent_Identity=23.7822349570201, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538512, Length=349, Percent_Identity=23.7822349570201, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI115537133, Length=322, Percent_Identity=21.1180124223602, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324188, Length=332, Percent_Identity=30.421686746988, Blast_Score=172, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24645260, Length=327, Percent_Identity=22.6299694189602, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45553183, Length=244, Percent_Identity=26.6393442622951, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17737615, Length=244, Percent_Identity=26.6393442622951, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24666073, Length=238, Percent_Identity=26.890756302521, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 36333; Mature: 36333

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00485 A_DEAMINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKKAELHVHLEGTISPELAKKLAKRNQLTLPNGLIAPDEKSYLSKDFLDFLKVYDTLA
CCCCEEEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SVIKNPQDYYDITFDYLKSNAQEHAIYIEMMYSPDHAEQSSGIPSKEHLAAIQQAIDDAK
HHHCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHH
SQFDIVGRIIITAVRHFGVEACERVAKQASIDKFPCVTGFGLGGDEAKFPPQLFTKAYQI
HHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHH
AADSGLECTVHAGEFDSAKGMEEAMKTLPIKRIGHGVRVIDSPDIMAMVKDQGIALEVCP
HCCCCCEEEEECCCCCCCCCHHHHHHHCCHHHHCCCEEEECCCCEEEEEECCCEEEEECC
TSNIFLGLFKDMNSHPFPKLYEAGIKVSINSDDPPFMSTTLAQEYKRVQKAYGYNNDTMN
CCCHHHHHHHHCCCCCCHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
NITRMAIEAAFVDEKTRKELLTKLEQ
HHHHHHHHHHHHCHHHHHHHHHHHCC
>Mature Secondary Structure
MNLKKAELHVHLEGTISPELAKKLAKRNQLTLPNGLIAPDEKSYLSKDFLDFLKVYDTLA
CCCCEEEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SVIKNPQDYYDITFDYLKSNAQEHAIYIEMMYSPDHAEQSSGIPSKEHLAAIQQAIDDAK
HHHCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHH
SQFDIVGRIIITAVRHFGVEACERVAKQASIDKFPCVTGFGLGGDEAKFPPQLFTKAYQI
HHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHH
AADSGLECTVHAGEFDSAKGMEEAMKTLPIKRIGHGVRVIDSPDIMAMVKDQGIALEVCP
HCCCCCEEEEECCCCCCCCCHHHHHHHCCHHHHCCCEEEECCCCEEEEEECCCEEEEECC
TSNIFLGLFKDMNSHPFPKLYEAGIKVSINSDDPPFMSTTLAQEYKRVQKAYGYNNDTMN
CCCHHHHHHHHCCCCCCHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
NITRMAIEAAFVDEKTRKELLTKLEQ
HHHHHHHHHHHHCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA