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The map label for this gene is pitA [C]

Identifier: 52840820

GI number: 52840820

Start: 617366

End: 618619

Strand: Reverse

Name: pitA [C]

Synonym: lpg0583

Alternate gene names: 52840820

Gene position: 618619-617366 (Counterclockwise)

Preceding gene: 52840821

Following gene: 52840817

Centisome position: 18.21

GC content: 41.95

Gene sequence:

>1254_bases
ATGGATTATTCAATTTACCTACTTTTTGCTGCTCTTATTCTTTGTTTTCTTATGACCTGGGGGGTCGGTGCCAATGATTT
GGCTAATGTCATGAGTACCACTATGGGCTCAAAGGCAGTTACCGTCCGTCAAGCCATGCTTATCGCCATCATTTTCGAAT
TTGCAGGCGCTTTTTTAGGGGGTGAAGGTGTCACTGAAACCATGCGTGATGGGATTATCAATACCAGTCAACTCTCTAAT
GAACCATTAATCCTCATCGAAGGCATGCTGTGCGTTTTGTTTGCCTGCACAATATGGATGAATCTTGCGAGTTATCTGGG
GGTCCCTGTTTCGATAACCAACGCATTAGTAGGCTCGATGGTTGGTTTTGGCACTATAGTCTTGGGTCCTGACGCAATAC
ATTGGAACCAGGTAGCGCGAATCGCTATTGGATGGATTTCATCTCCGTTGATTTCAGGGATTACGGCCTACGCTTTGTTC
ATTAGTATACAGCAAACCATATTTGTAAAAAGTAACCCGTTGACTAAAGCTAAGCTATATATTCCTATTTATCTTTTTTT
GATTGGTTTTATATTATCTTTTATCACTGTATTTAAAGGACTTAACCATTTTGATATTCACTTGAATTTAAAGCAAGATT
TGGCGGTGACTCTGGCCACCAGTATAATAATTACAATTCTGGGTATGATCTTTATTAAGCGTATTCCTGAATACCATAAA
ATAAGACGCAGGGAACGATTTATTCAGGTAGAGAAGTATTTTGCTGTGCTCATGGCAATGACGGCATGCGCTATGGCTTT
CGCTCATGGCTCCAACGATGTTGCCCTGGCTGTTGGACCATTAAGTATTGTGCACAGCCTGGTCATGCATTCCAATCAAA
TATTTGACGCAGATAACTACCCTTCCTGGATTATTTTATTAGGTTGCGTCGGAGTAGTAACTGGTTTCCTTATGTATGGA
AGAAAAGTCATTGAAACCGTAGGAAGTTCTATCACTGCTTTAACGCCCAGCCGTGCATTTGCTGCAACACTTTCTGCAGC
AACTACCGTAGTTGTTGCAACCAGCACCGGAATCCCTGTTTCGGCGACTCAAACTCTGGTTGGTGCCGTTTTAGGTGTAG
GTTTGGCAAGAGGTATCGGCGCTTTGAATCTCATTGTAATCCGTAATATCTTTATGTCATGGGTACTGACATTACCCGCA
GCCTCCATGCTAACGATCTTATCCTATAAACTTTTACATGCTTTGTTGGGATAA

Upstream 100 bases:

>100_bases
TTTTCTATACAAACTGGTCCAATGGATTGGCGAATTGGCTGACCATGCCCAGACAGTTGGTGGTCGACTTCAAATTCTAA
TTGCCCGGTAGTTATCACTC

Downstream 100 bases:

>100_bases
TCCTCATTGCCTATCAGCTCATCATAGGCAATGGATTGCCTAAATTTCAACGCCTACTGTAATATGAAAATGAATTGAAT
ATCCTTTAAAATATAAATTC

Product: phosphate transporter

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MDYSIYLLFAALILCFLMTWGVGANDLANVMSTTMGSKAVTVRQAMLIAIIFEFAGAFLGGEGVTETMRDGIINTSQLSN
EPLILIEGMLCVLFACTIWMNLASYLGVPVSITNALVGSMVGFGTIVLGPDAIHWNQVARIAIGWISSPLISGITAYALF
ISIQQTIFVKSNPLTKAKLYIPIYLFLIGFILSFITVFKGLNHFDIHLNLKQDLAVTLATSIIITILGMIFIKRIPEYHK
IRRRERFIQVEKYFAVLMAMTACAMAFAHGSNDVALAVGPLSIVHSLVMHSNQIFDADNYPSWIILLGCVGVVTGFLMYG
RKVIETVGSSITALTPSRAFAATLSAATTVVVATSTGIPVSATQTLVGAVLGVGLARGIGALNLIVIRNIFMSWVLTLPA
ASMLTILSYKLLHALLG

Sequences:

>Translated_417_residues
MDYSIYLLFAALILCFLMTWGVGANDLANVMSTTMGSKAVTVRQAMLIAIIFEFAGAFLGGEGVTETMRDGIINTSQLSN
EPLILIEGMLCVLFACTIWMNLASYLGVPVSITNALVGSMVGFGTIVLGPDAIHWNQVARIAIGWISSPLISGITAYALF
ISIQQTIFVKSNPLTKAKLYIPIYLFLIGFILSFITVFKGLNHFDIHLNLKQDLAVTLATSIIITILGMIFIKRIPEYHK
IRRRERFIQVEKYFAVLMAMTACAMAFAHGSNDVALAVGPLSIVHSLVMHSNQIFDADNYPSWIILLGCVGVVTGFLMYG
RKVIETVGSSITALTPSRAFAATLSAATTVVVATSTGIPVSATQTLVGAVLGVGLARGIGALNLIVIRNIFMSWVLTLPA
ASMLTILSYKLLHALLG
>Mature_417_residues
MDYSIYLLFAALILCFLMTWGVGANDLANVMSTTMGSKAVTVRQAMLIAIIFEFAGAFLGGEGVTETMRDGIINTSQLSN
EPLILIEGMLCVLFACTIWMNLASYLGVPVSITNALVGSMVGFGTIVLGPDAIHWNQVARIAIGWISSPLISGITAYALF
ISIQQTIFVKSNPLTKAKLYIPIYLFLIGFILSFITVFKGLNHFDIHLNLKQDLAVTLATSIIITILGMIFIKRIPEYHK
IRRRERFIQVEKYFAVLMAMTACAMAFAHGSNDVALAVGPLSIVHSLVMHSNQIFDADNYPSWIILLGCVGVVTGFLMYG
RKVIETVGSSITALTPSRAFAATLSAATTVVVATSTGIPVSATQTLVGAVLGVGLARGIGALNLIVIRNIFMSWVLTLPA
ASMLTILSYKLLHALLG

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=287, Percent_Identity=28.5714285714286, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI5803173, Length=184, Percent_Identity=34.2391304347826, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71981576, Length=440, Percent_Identity=29.7727272727273, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI32566716, Length=477, Percent_Identity=28.3018867924528, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI25146401, Length=203, Percent_Identity=34.4827586206897, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17539280, Length=286, Percent_Identity=30.0699300699301, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17557328, Length=494, Percent_Identity=22.8744939271255, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17536725, Length=170, Percent_Identity=35.8823529411765, Blast_Score=101, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6319773, Length=165, Percent_Identity=38.7878787878788, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356511, Length=193, Percent_Identity=32.1243523316062, Blast_Score=118, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 44908; Mature: 44908

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYSIYLLFAALILCFLMTWGVGANDLANVMSTTMGSKAVTVRQAMLIAIIFEFAGAFLG
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
GEGVTETMRDGIINTSQLSNEPLILIEGMLCVLFACTIWMNLASYLGVPVSITNALVGSM
CCCHHHHHHCCCCCCHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VGFGTIVLGPDAIHWNQVARIAIGWISSPLISGITAYALFISIQQTIFVKSNPLTKAKLY
HHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHH
IPIYLFLIGFILSFITVFKGLNHFDIHLNLKQDLAVTLATSIIITILGMIFIKRIPEYHK
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IRRRERFIQVEKYFAVLMAMTACAMAFAHGSNDVALAVGPLSIVHSLVMHSNQIFDADNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCEECCCCC
PSWIILLGCVGVVTGFLMYGRKVIETVGSSITALTPSRAFAATLSAATTVVVATSTGIPV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHEEEEEECCCCCC
SATQTLVGAVLGVGLARGIGALNLIVIRNIFMSWVLTLPAASMLTILSYKLLHALLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDYSIYLLFAALILCFLMTWGVGANDLANVMSTTMGSKAVTVRQAMLIAIIFEFAGAFLG
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
GEGVTETMRDGIINTSQLSNEPLILIEGMLCVLFACTIWMNLASYLGVPVSITNALVGSM
CCCHHHHHHCCCCCCHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VGFGTIVLGPDAIHWNQVARIAIGWISSPLISGITAYALFISIQQTIFVKSNPLTKAKLY
HHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHH
IPIYLFLIGFILSFITVFKGLNHFDIHLNLKQDLAVTLATSIIITILGMIFIKRIPEYHK
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IRRRERFIQVEKYFAVLMAMTACAMAFAHGSNDVALAVGPLSIVHSLVMHSNQIFDADNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCCEECCCCC
PSWIILLGCVGVVTGFLMYGRKVIETVGSSITALTPSRAFAATLSAATTVVVATSTGIPV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHEEEEEECCCCCC
SATQTLVGAVLGVGLARGIGALNLIVIRNIFMSWVLTLPAASMLTILSYKLLHALLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]