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The map label for this gene is kynB [H]

Identifier: 39998438

GI number: 39998438

Start: 3680526

End: 3681209

Strand: Direct

Name: kynB [H]

Synonym: GSU3349

Alternate gene names: 39998438

Gene position: 3680526-3681209 (Clockwise)

Preceding gene: 39998437

Following gene: 39998439

Centisome position: 96.5

GC content: 66.23

Gene sequence:

>684_bases
ATGAAGATCATCGACATCACCGTCTCTCTCTCCCCCGATCTCCCCGTTTACCCCGGAGACCCGCCCTTCTCGCTCGAACC
AGTGGCCCGCGTGGCCCGGGGCGACGGCGCCAACGTCTCGCGCATCACCCTCGGGACCCACGCCGGCACTCACATCGACG
TTCCGCGACATCTGCGCGACGACGGCGCCTCCGTGGACCAGGTGCCCCTTGATCTGCTGACGGGCAAAGCCCGGGTGATC
GAGCTGCACGATGTGATCGCCATCGGACGCCGGGAGCTGGCCCATCTGCCGGTAAAGGGAGAAGAGCGGATCATCCTCAA
GACCGCCAACTCCCGCCTCTGGAGCCACGCCGGCTTCCTCGACAGTTATGCTTCGCTTACTCCCGACGGCGCCCGCTATC
TGGCGGAGGTGGGGACGCGCCTGGTGGGGATCGATTACCTCTCCATCGGCCCCTTCGGCAACGAGGCTGAGGTCCACCAG
ATCCTTCTGGACGCCGGCATCCTCATCCTGGAGGGGCTGAATCTCGCCGATGTCGAGCCGGGGCACTACGAACTCCTCTG
CCTCCCCCTCAAGATAGCCGGCGGAGACGGCGCACCGGCACGCGCACTCCTTCGTTCCTTCGCGCGGGTAGCGGCCGGGG
AATCCTCCTTCGACCCCCATACCACTCGCTGGCCCCTTTCCTGA

Upstream 100 bases:

>100_bases
TCTCGAAAATTCCTCCGCTGGCGGTATACTCTGTATCGTGGGACCGCAAGGCGCAGGCCGGCCTCGCGGTCCCGCCGCCC
CCACCGCAGCGGAGGTCCCC

Downstream 100 bases:

>100_bases
GGCAGTGACCGTGACGCGCCGGCGCACGATCGTCAGTTCGCGGGAGCTCGACCTCCTGCGCCGCCTGCTCATGGAGCGGA
CCGAGGAACTGGAGCGCGTC

Product: cyclase

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKIIDITVSLSPDLPVYPGDPPFSLEPVARVARGDGANVSRITLGTHAGTHIDVPRHLRDDGASVDQVPLDLLTGKARVI
ELHDVIAIGRRELAHLPVKGEERIILKTANSRLWSHAGFLDSYASLTPDGARYLAEVGTRLVGIDYLSIGPFGNEAEVHQ
ILLDAGILILEGLNLADVEPGHYELLCLPLKIAGGDGAPARALLRSFARVAAGESSFDPHTTRWPLS

Sequences:

>Translated_227_residues
MKIIDITVSLSPDLPVYPGDPPFSLEPVARVARGDGANVSRITLGTHAGTHIDVPRHLRDDGASVDQVPLDLLTGKARVI
ELHDVIAIGRRELAHLPVKGEERIILKTANSRLWSHAGFLDSYASLTPDGARYLAEVGTRLVGIDYLSIGPFGNEAEVHQ
ILLDAGILILEGLNLADVEPGHYELLCLPLKIAGGDGAPARALLRSFARVAAGESSFDPHTTRWPLS
>Mature_227_residues
MKIIDITVSLSPDLPVYPGDPPFSLEPVARVARGDGANVSRITLGTHAGTHIDVPRHLRDDGASVDQVPLDLLTGKARVI
ELHDVIAIGRRELAHLPVKGEERIILKTANSRLWSHAGFLDSYASLTPDGARYLAEVGTRLVGIDYLSIGPFGNEAEVHQ
ILLDAGILILEGLNLADVEPGHYELLCLPLKIAGGDGAPARALLRSFARVAAGESSFDPHTTRWPLS

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 24348; Mature: 24348

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIDITVSLSPDLPVYPGDPPFSLEPVARVARGDGANVSRITLGTHAGTHIDVPRHLRD
CEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCCEECCCHHHCC
DGASVDQVPLDLLTGKARVIELHDVIAIGRRELAHLPVKGEERIILKTANSRLWSHAGFL
CCCCCCCCCHHHHCCCEEEEEHHHHHHHCCHHHEECCCCCCCEEEEEECCCCHHHHHCHH
DSYASLTPDGARYLAEVGTRLVGIDYLSIGPFGNEAEVHQILLDAGILILEGLNLADVEP
HHHHHCCCCHHHHHHHHCCEEEEEEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCC
GHYELLCLPLKIAGGDGAPARALLRSFARVAAGESSFDPHTTRWPLS
CCEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIIDITVSLSPDLPVYPGDPPFSLEPVARVARGDGANVSRITLGTHAGTHIDVPRHLRD
CEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCCEECCCHHHCC
DGASVDQVPLDLLTGKARVIELHDVIAIGRRELAHLPVKGEERIILKTANSRLWSHAGFL
CCCCCCCCCHHHHCCCEEEEEHHHHHHHCCHHHEECCCCCCCEEEEEECCCCHHHHHCHH
DSYASLTPDGARYLAEVGTRLVGIDYLSIGPFGNEAEVHQILLDAGILILEGLNLADVEP
HHHHHCCCCHHHHHHHHCCEEEEEEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCC
GHYELLCLPLKIAGGDGAPARALLRSFARVAAGESSFDPHTTRWPLS
CCEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA