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The map label for this gene is hslO

Identifier: 39998437

GI number: 39998437

Start: 3679517

End: 3680422

Strand: Direct

Name: hslO

Synonym: GSU3348

Alternate gene names: 39998437

Gene position: 3679517-3680422 (Clockwise)

Preceding gene: 39998436

Following gene: 39998438

Centisome position: 96.47

GC content: 64.02

Gene sequence:

>906_bases
ATGGGAAACAGCACTGAGTCGGTCATCACTGACTATCTTGTCCGCATTATCACCCGGGAAGGCAATATCCGAGCACTCGC
CTGCGTAACCACCAACCTGGTGGGAGACGCATGCCGCCGGCACGGTACCCTGCCCACGGCCTCGGCCGCCCTGGGGCGGG
CCCTGACCGGCGGCGTCCTCATGGGGGCCCTTCTCAAGACCGGTCAACGGATTGCCCTCACCTTCGAGGGGAATGGTCCC
CTGAAAAAGATCATCGTGGAAGCGGACGCCAACGGCGCCGTGCGCGGGCTCGTCAGGAATCCGGCGGTGAGCCTTCTGAG
GGACGACGGCAAACTCGACGTGGCCGGAGCCCTGGGGAAGGCCGGATTTCTTACCGTCAGCCGGGACCTGGGGCTCAAGG
AGCCCTACACCGGCACGGTCATGCTCTATACCAGCGAGATCGCCGAGGACTTGGCCTGGTACCTGACCGAATCGGAGCAG
ATCCCCTCAGCCGTTGGTCTCGGCGTGTACGTGGAGCAGGACGGGTCGGTTGCCGCTGCCGGCGGCTTTCTGATCCAGGC
GCTGCCCCCCGGCGACGACCAACTCATCGACCGGATCATGGAGCGAATCGCCTCCATGCCGCCGGTAACGGAAATGCTCC
GGGCCGGGGCAACCCCTGAAGGACTTCTGGAGTACCTCTTCGACGGCATCCCCTTCGACATCCTTGAAAAACGGGCCACG
GCACTCGTCTGCTCATGCAGCCGCGAACGGATCGAACGGGTGCTCCTCTCCCTGGGGAGCGACGAACTCTCCTCCCTGAT
CCACGACCAGGGCGAGGCCTCTGTCGGGTGCGAATTCTGCGGCGAACACTATAACTTCACACGGGAAGAACTGGAACGGC
TCAGGGACTCCCTCACCGCCGTCTGA

Upstream 100 bases:

>100_bases
AAATCACAGAGTAAGCCCGGGAAATTTTCCTCCGGTTTTCCTCTGGGTGCTTTGTGGTCAAAAAAAGGTTCTGGAAAAAC
CGGTCTGTAAGGATAGAGCA

Downstream 100 bases:

>100_bases
CCCTCTCGAAAATTCCTCCGCTGGCGGTATACTCTGTATCGTGGGACCGCAAGGCGCAGGCCGGCCTCGCGGTCCCGCCG
CCCCCACCGCAGCGGAGGTC

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MGNSTESVITDYLVRIITREGNIRALACVTTNLVGDACRRHGTLPTASAALGRALTGGVLMGALLKTGQRIALTFEGNGP
LKKIIVEADANGAVRGLVRNPAVSLLRDDGKLDVAGALGKAGFLTVSRDLGLKEPYTGTVMLYTSEIAEDLAWYLTESEQ
IPSAVGLGVYVEQDGSVAAAGGFLIQALPPGDDQLIDRIMERIASMPPVTEMLRAGATPEGLLEYLFDGIPFDILEKRAT
ALVCSCSRERIERVLLSLGSDELSSLIHDQGEASVGCEFCGEHYNFTREELERLRDSLTAV

Sequences:

>Translated_301_residues
MGNSTESVITDYLVRIITREGNIRALACVTTNLVGDACRRHGTLPTASAALGRALTGGVLMGALLKTGQRIALTFEGNGP
LKKIIVEADANGAVRGLVRNPAVSLLRDDGKLDVAGALGKAGFLTVSRDLGLKEPYTGTVMLYTSEIAEDLAWYLTESEQ
IPSAVGLGVYVEQDGSVAAAGGFLIQALPPGDDQLIDRIMERIASMPPVTEMLRAGATPEGLLEYLFDGIPFDILEKRAT
ALVCSCSRERIERVLLSLGSDELSSLIHDQGEASVGCEFCGEHYNFTREELERLRDSLTAV
>Mature_300_residues
GNSTESVITDYLVRIITREGNIRALACVTTNLVGDACRRHGTLPTASAALGRALTGGVLMGALLKTGQRIALTFEGNGPL
KKIIVEADANGAVRGLVRNPAVSLLRDDGKLDVAGALGKAGFLTVSRDLGLKEPYTGTVMLYTSEIAEDLAWYLTESEQI
PSAVGLGVYVEQDGSVAAAGGFLIQALPPGDDQLIDRIMERIASMPPVTEMLRAGATPEGLLEYLFDGIPFDILEKRATA
LVCSCSRERIERVLLSLGSDELSSLIHDQGEASVGCEFCGEHYNFTREELERLRDSLTAV

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=288, Percent_Identity=23.9583333333333, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_GEOSL (Q747B9)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_954388.1
- ProteinModelPortal:   Q747B9
- SMR:   Q747B9
- GeneID:   2686440
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU3348
- NMPDR:   fig|243231.1.peg.3326
- TIGR:   GSU3348
- HOGENOM:   HBG286231
- OMA:   AMTIDQG
- ProtClustDB:   PRK00114
- BioCyc:   GSUL243231:GSU_3348-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 32142; Mature: 32011

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNSTESVITDYLVRIITREGNIRALACVTTNLVGDACRRHGTLPTASAALGRALTGGVL
CCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MGALLKTGQRIALTFEGNGPLKKIIVEADANGAVRGLVRNPAVSLLRDDGKLDVAGALGK
HHHHHHCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHCHHHHHHHCCCCEEEHHHCCC
AGFLTVSRDLGLKEPYTGTVMLYTSEIAEDLAWYLTESEQIPSAVGLGVYVEQDGSVAAA
CCEEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCHHHCCCEEEECCCCEEEC
GGFLIQALPPGDDQLIDRIMERIASMPPVTEMLRAGATPEGLLEYLFDGIPFDILEKRAT
CCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
ALVCSCSRERIERVLLSLGSDELSSLIHDQGEASVGCEFCGEHYNFTREELERLRDSLTA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCC
V
C
>Mature Secondary Structure 
GNSTESVITDYLVRIITREGNIRALACVTTNLVGDACRRHGTLPTASAALGRALTGGVL
CCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
MGALLKTGQRIALTFEGNGPLKKIIVEADANGAVRGLVRNPAVSLLRDDGKLDVAGALGK
HHHHHHCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHCHHHHHHHCCCCEEEHHHCCC
AGFLTVSRDLGLKEPYTGTVMLYTSEIAEDLAWYLTESEQIPSAVGLGVYVEQDGSVAAA
CCEEEEECCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCHHHCCCEEEECCCCEEEC
GGFLIQALPPGDDQLIDRIMERIASMPPVTEMLRAGATPEGLLEYLFDGIPFDILEKRAT
CCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
ALVCSCSRERIERVLLSLGSDELSSLIHDQGEASVGCEFCGEHYNFTREELERLRDSLTA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA