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The map label for this gene is nreC [H]

Identifier: 39998319

GI number: 39998319

Start: 3543991

End: 3544680

Strand: Reverse

Name: nreC [H]

Synonym: GSU3229

Alternate gene names: 39998319

Gene position: 3544680-3543991 (Counterclockwise)

Preceding gene: 39998320

Following gene: 39998304

Centisome position: 92.94

GC content: 63.19

Gene sequence:

>690_bases
ATGTATGCTAAGAAGCGGGTCATGATCGTGGATGACCATCCCTTGTTCCGGGATGGTCTCAAGGGGCTCGTCTCACGCAG
CGCCGATTACCAGGCCGTGGGAGAGGCGGGCAGCGGCAGCGAGGCCCTGCGCCAGGTGGAAAAGTGCCGGCCCGACCTGA
TCACCATGGATATCTCGCTGCCGGACATGAGCGGCATCGACGCGGCGCGGGAGATCCACCGTGTGGCTCCCCACGTGAAA
ATTCTCATGGTGAGCATGCATCCGCGCTATGAGTTCATCGCCGACGCCTTTAAGGCCGGAGCCAGCGGCTACGTGGTCAA
GGAAGCCACCAGTGCCCGGCTGATTCAGGCCATGGACGCCCTGAGCCGCGGCGAGTTCTTTCTGGACGGGCAGGTTTCCC
AGGAGGTGGTGCAGAGGATATTCAGCGGGTCGCAGGCTGATGGAGGCGGCTCGGCCGATGAGCGGTACACCCTGCTGACG
CCCCGTGAGCAACAGGTGATGCGGATGATCGTGGAGGGCGCTACGTCGAGACAGATCGCCGAGAGCCTTGAACTGACCCT
CAAGACGGTGGAGAACCACCGGACCAACCTCATGCGGAAGCTCCAGGTGCACAGTAAGCTGGAGCTTGTCCGCTACGCCG
CCCGGCTCGGGCTCATCGACCTGGAGAGCTGGAGGGGCAACGAGCAGTAG

Upstream 100 bases:

>100_bases
ACCGTGGAGGTCCCGTTCCGCAAGGCCCCGCCGGGCCGAACCACTGCCGCGAAGGGGCGGCCGAGCCTCCCCTACCCGGT
GCGCGGGAGGAAATCACTCT

Downstream 100 bases:

>100_bases
GCCGCACCCGGAACCCGCTTCCGGCTTCTTTCTTGTTATGGCGCTGTCCTCTGGGCAGCGCTTTTTTTTGTGTGTGTTGA
AGAGATGAGCGGGACCATGA

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MYAKKRVMIVDDHPLFRDGLKGLVSRSADYQAVGEAGSGSEALRQVEKCRPDLITMDISLPDMSGIDAAREIHRVAPHVK
ILMVSMHPRYEFIADAFKAGASGYVVKEATSARLIQAMDALSRGEFFLDGQVSQEVVQRIFSGSQADGGGSADERYTLLT
PREQQVMRMIVEGATSRQIAESLELTLKTVENHRTNLMRKLQVHSKLELVRYAARLGLIDLESWRGNEQ

Sequences:

>Translated_229_residues
MYAKKRVMIVDDHPLFRDGLKGLVSRSADYQAVGEAGSGSEALRQVEKCRPDLITMDISLPDMSGIDAAREIHRVAPHVK
ILMVSMHPRYEFIADAFKAGASGYVVKEATSARLIQAMDALSRGEFFLDGQVSQEVVQRIFSGSQADGGGSADERYTLLT
PREQQVMRMIVEGATSRQIAESLELTLKTVENHRTNLMRKLQVHSKLELVRYAARLGLIDLESWRGNEQ
>Mature_229_residues
MYAKKRVMIVDDHPLFRDGLKGLVSRSADYQAVGEAGSGSEALRQVEKCRPDLITMDISLPDMSGIDAAREIHRVAPHVK
ILMVSMHPRYEFIADAFKAGASGYVVKEATSARLIQAMDALSRGEFFLDGQVSQEVVQRIFSGSQADGGGSADERYTLLT
PREQQVMRMIVEGATSRQIAESLELTLKTVENHRTNLMRKLQVHSKLELVRYAARLGLIDLESWRGNEQ

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=218, Percent_Identity=31.1926605504587, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788521, Length=202, Percent_Identity=30.6930693069307, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790102, Length=210, Percent_Identity=32.8571428571429, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1786747, Length=214, Percent_Identity=28.5046728971963, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787473, Length=187, Percent_Identity=29.4117647058824, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788712, Length=208, Percent_Identity=27.4038461538462, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788546, Length=216, Percent_Identity=26.3888888888889, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI87082052, Length=199, Percent_Identity=29.1457286432161, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25521; Mature: 25521

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAKKRVMIVDDHPLFRDGLKGLVSRSADYQAVGEAGSGSEALRQVEKCRPDLITMDISL
CCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEEEECC
PDMSGIDAAREIHRVAPHVKILMVSMHPRYEFIADAFKAGASGYVVKEATSARLIQAMDA
CCCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHH
LSRGEFFLDGQVSQEVVQRIFSGSQADGGGSADERYTLLTPREQQVMRMIVEGATSRQIA
HHCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCHHHHH
ESLELTLKTVENHRTNLMRKLQVHSKLELVRYAARLGLIDLESWRGNEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCC
>Mature Secondary Structure
MYAKKRVMIVDDHPLFRDGLKGLVSRSADYQAVGEAGSGSEALRQVEKCRPDLITMDISL
CCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEEEECC
PDMSGIDAAREIHRVAPHVKILMVSMHPRYEFIADAFKAGASGYVVKEATSARLIQAMDA
CCCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHH
LSRGEFFLDGQVSQEVVQRIFSGSQADGGGSADERYTLLTPREQQVMRMIVEGATSRQIA
HHCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCHHHHH
ESLELTLKTVENHRTNLMRKLQVHSKLELVRYAARLGLIDLESWRGNEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA