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The map label for this gene is flhA [H]

Identifier: 39998147

GI number: 39998147

Start: 3357658

End: 3359748

Strand: Reverse

Name: flhA [H]

Synonym: GSU3056

Alternate gene names: 39998147

Gene position: 3359748-3357658 (Counterclockwise)

Preceding gene: 39998148

Following gene: 308513335

Centisome position: 88.09

GC content: 62.31

Gene sequence:

>2091_bases
ATGGCCAACACGGCGGTGGACGCAGTCGATCTCCAGCCTGCAAAAAGCAATTCGGATATCTATATGGCTGTGGCGCTGAT
CGGCGTCCTGGCCCTAATGATCATCCCGTTGCCGGCGTTTCTGCTGGACCTGTTCCTGGCCGCCAACATAACCATTGCGC
TGGCAATTCTGCTGGTGGCCCTCTACACCCAGCAGCCTCTGGATTTCTCGGTATTCCCGTCGGTACTGCTGGTTACAACG
CTTTTCCGGCTGGCGCTGAACGTGGCCGGCACCCGGCTCATTCTCCTCCACGGCAACGAAGGAGTCGATGCCGCCGGGCA
CGTGATCAAGGCCTTCGGCCAGTTCGTGGTCGGCGGCAACTATGTGGTCGGCGCGGTCATCTTCCTGATTCTGGTCATCA
TCAACTTCGTGGTCATCACCAAGGGTGCCGGCAGGGTGGCCGAGGTGGCGGCCCGCTTCACCCTCGATGCAATGCCCGGC
AAGCAGATGGCCATCGATGCGGATCTCTCCTCGGGGCTCATCAACGAGAAAGAGGCCCGGCGCCGCCGGTCGCGGGTGTC
ACGCGAAGCCGATTTCTACGGCTCCATGGACGGTGCCAGCAAGTTCGTGCGTGGCGATGCGGTCGCCGGCATCCTGATCA
TGCTGGTCAACATCATTGGCGGGTTCATTATCGGGGTCTGGCAGAACGGCATGCCCCTGGAGGCCGCCCTCTCGAACTAC
ACGCTGCTGACCATCGGCGAGGGGCTCGTGGCCCAGATCCCGGCACTCATCATCTCCACTGCCGCCGGTATTATCGTAAC
GCGCTCGGCCGACGAGAAGAACTTCGGCCACGAGATTTCGGGCCAGTTCCTCAACTATCCCAAGGCATTCTATGTCTCCT
CGGGGGTTCTCTTCGCCTTCGGCCTCATCCCGGGGCTTCCCCATGTGGCCTTCTTCCTCCTGTCCGGAGCGGCCTACATG
GCGGGCAGGCTGGCCAAGGAGAGAGCCCAGGTGGTGGAGGACGACCTCATGACGCTGCCGGCACCGGCGGAGACCGGGGA
GTCCGGCGACCAGGCCGGCGCCATCCGCCCTCTGGACATGCTGGAGCTGGAGGTCGGGTACGGTCTCGTCCCCATGGTGG
ATGCGGCCCAGGAAGGCGAGCTTCTGGAGCGGATTCGCTCGATTCGTCGCCAGTATGCCCAGAAGATGGGATTCGTGGTG
CCTCCGGTCCACATCCACGACAACCTGCAACTCAAGCCCCACGAGTACAACATCCTCATCAAGGGTGCCAAGGTCGGCGG
CGGCGAGATGATCGGCCAGTACCTGGCCATGGATTCGGGCGCCGTTTCCATGCCGGTCGAGGGCGTCCGGACCACGGAGC
CGGTATTCGGGCTCCCCGCAATCTGGATCAGACCCGAACTGAAGGAACAGGCACAGCTGGCGGGCTACACCGTGGTGGAC
AGCACCACCATCATCGCCACGCACATCAGCGAGATCATCCGCAAGCATTCCCACGAAATGGTGGGACGCCAGGAGCTCCA
GCAGCTGCTGGACAACCTTTCCTCCTCCTTCCCCAAGGTTGTGGAAGACCTGGTGCCGAACCTCCTGAACTTGGGAACCG
TGCTGCGTGTCGTCAGGAACCTGCTGCGGGAAGGGGTTTCCATCCGCGATCTGCGGACCGTGCTGGAGACCCTGGCCGAC
TACGGCGGGCTTACCAAGGACCCGGACACCCTGACCGAGTTCGTCCGCCAGGGACTGGGCCGCTCCATCGTGGAGCAATA
CAAGCGGGACGACGACACCCTGTGTCTCATCAGCCTCGACCGCCGGGTCGAGGAGGTCGTGGCCGAGGCGATCCAACCGT
CGGATCAGGGGAGCTACCTGGCCATCGAACCCAATACGGCCCAGCTGATCCTCTCCGGGATTCGGCAGGAGATGGAAAAA
TTCAACCAGATCGGAACCCAGCCGGTACTGCTGGCTTCGCCGTCCATCCGGCGGCATGTCAAAAAGCTCACCGAGCGGTT
CGTGCCCAATCTGGTCGTTCTGTCGCACAACGAGGTGCCGTCAGGCATAAAAATCCAATCGTTAGGGGTGGTGACGCTCA
ATGCTGGTTAA

Upstream 100 bases:

>100_bases
CCAATGTTACCTGCTCGTTTCTACTTTAGTTAGCTGGCACAACGGTTGCACATAGAGTGGTGCGCACGAAAAGCGCTTGA
TTTTACGAGAGGAATTTCTC

Downstream 100 bases:

>100_bases
GACTTTCGAAGCGGTGGATATGTCCGAAGCCCTCCGGATGGTGAAGGCCGAACTGGGGCCCGACGCCATGATCATTTCTT
CCAAGAAGGAGCGGAAGAAA

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 695

Protein sequence:

>696_residues
MANTAVDAVDLQPAKSNSDIYMAVALIGVLALMIIPLPAFLLDLFLAANITIALAILLVALYTQQPLDFSVFPSVLLVTT
LFRLALNVAGTRLILLHGNEGVDAAGHVIKAFGQFVVGGNYVVGAVIFLILVIINFVVITKGAGRVAEVAARFTLDAMPG
KQMAIDADLSSGLINEKEARRRRSRVSREADFYGSMDGASKFVRGDAVAGILIMLVNIIGGFIIGVWQNGMPLEAALSNY
TLLTIGEGLVAQIPALIISTAAGIIVTRSADEKNFGHEISGQFLNYPKAFYVSSGVLFAFGLIPGLPHVAFFLLSGAAYM
AGRLAKERAQVVEDDLMTLPAPAETGESGDQAGAIRPLDMLELEVGYGLVPMVDAAQEGELLERIRSIRRQYAQKMGFVV
PPVHIHDNLQLKPHEYNILIKGAKVGGGEMIGQYLAMDSGAVSMPVEGVRTTEPVFGLPAIWIRPELKEQAQLAGYTVVD
STTIIATHISEIIRKHSHEMVGRQELQQLLDNLSSSFPKVVEDLVPNLLNLGTVLRVVRNLLREGVSIRDLRTVLETLAD
YGGLTKDPDTLTEFVRQGLGRSIVEQYKRDDDTLCLISLDRRVEEVVAEAIQPSDQGSYLAIEPNTAQLILSGIRQEMEK
FNQIGTQPVLLASPSIRRHVKKLTERFVPNLVVLSHNEVPSGIKIQSLGVVTLNAG

Sequences:

>Translated_696_residues
MANTAVDAVDLQPAKSNSDIYMAVALIGVLALMIIPLPAFLLDLFLAANITIALAILLVALYTQQPLDFSVFPSVLLVTT
LFRLALNVAGTRLILLHGNEGVDAAGHVIKAFGQFVVGGNYVVGAVIFLILVIINFVVITKGAGRVAEVAARFTLDAMPG
KQMAIDADLSSGLINEKEARRRRSRVSREADFYGSMDGASKFVRGDAVAGILIMLVNIIGGFIIGVWQNGMPLEAALSNY
TLLTIGEGLVAQIPALIISTAAGIIVTRSADEKNFGHEISGQFLNYPKAFYVSSGVLFAFGLIPGLPHVAFFLLSGAAYM
AGRLAKERAQVVEDDLMTLPAPAETGESGDQAGAIRPLDMLELEVGYGLVPMVDAAQEGELLERIRSIRRQYAQKMGFVV
PPVHIHDNLQLKPHEYNILIKGAKVGGGEMIGQYLAMDSGAVSMPVEGVRTTEPVFGLPAIWIRPELKEQAQLAGYTVVD
STTIIATHISEIIRKHSHEMVGRQELQQLLDNLSSSFPKVVEDLVPNLLNLGTVLRVVRNLLREGVSIRDLRTVLETLAD
YGGLTKDPDTLTEFVRQGLGRSIVEQYKRDDDTLCLISLDRRVEEVVAEAIQPSDQGSYLAIEPNTAQLILSGIRQEMEK
FNQIGTQPVLLASPSIRRHVKKLTERFVPNLVVLSHNEVPSGIKIQSLGVVTLNAG
>Mature_695_residues
ANTAVDAVDLQPAKSNSDIYMAVALIGVLALMIIPLPAFLLDLFLAANITIALAILLVALYTQQPLDFSVFPSVLLVTTL
FRLALNVAGTRLILLHGNEGVDAAGHVIKAFGQFVVGGNYVVGAVIFLILVIINFVVITKGAGRVAEVAARFTLDAMPGK
QMAIDADLSSGLINEKEARRRRSRVSREADFYGSMDGASKFVRGDAVAGILIMLVNIIGGFIIGVWQNGMPLEAALSNYT
LLTIGEGLVAQIPALIISTAAGIIVTRSADEKNFGHEISGQFLNYPKAFYVSSGVLFAFGLIPGLPHVAFFLLSGAAYMA
GRLAKERAQVVEDDLMTLPAPAETGESGDQAGAIRPLDMLELEVGYGLVPMVDAAQEGELLERIRSIRRQYAQKMGFVVP
PVHIHDNLQLKPHEYNILIKGAKVGGGEMIGQYLAMDSGAVSMPVEGVRTTEPVFGLPAIWIRPELKEQAQLAGYTVVDS
TTIIATHISEIIRKHSHEMVGRQELQQLLDNLSSSFPKVVEDLVPNLLNLGTVLRVVRNLLREGVSIRDLRTVLETLADY
GGLTKDPDTLTEFVRQGLGRSIVEQYKRDDDTLCLISLDRRVEEVVAEAIQPSDQGSYLAIEPNTAQLILSGIRQEMEKF
NQIGTQPVLLASPSIRRHVKKLTERFVPNLVVLSHNEVPSGIKIQSLGVVTLNAG

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=668, Percent_Identity=49.1017964071856, Blast_Score=628, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75289; Mature: 75158

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTAVDAVDLQPAKSNSDIYMAVALIGVLALMIIPLPAFLLDLFLAANITIALAILLVA
CCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYTQQPLDFSVFPSVLLVTTLFRLALNVAGTRLILLHGNEGVDAAGHVIKAFGQFVVGGN
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCC
YVVGAVIFLILVIINFVVITKGAGRVAEVAARFTLDAMPGKQMAIDADLSSGLINEKEAR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEECCHHCCCCCHHHHH
RRRSRVSREADFYGSMDGASKFVRGDAVAGILIMLVNIIGGFIIGVWQNGMPLEAALSNY
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCCCHHHHHCCC
TLLTIGEGLVAQIPALIISTAAGIIVTRSADEKNFGHEISGQFLNYPKAFYVSSGVLFAF
EEEEECCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHCCHHHCCCCHHHHCCHHHHHH
GLIPGLPHVAFFLLSGAAYMAGRLAKERAQVVEDDLMTLPAPAETGESGDQAGAIRPLDM
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
LELEVGYGLVPMVDAAQEGELLERIRSIRRQYAQKMGFVVPPVHIHDNLQLKPHEYNILI
HEECCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEECCCCEEEEE
KGAKVGGGEMIGQYLAMDSGAVSMPVEGVRTTEPVFGLPAIWIRPELKEQAQLAGYTVVD
EECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHCCEEEEC
STTIIATHISEIIRKHSHEMVGRQELQQLLDNLSSSFPKVVEDLVPNLLNLGTVLRVVRN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLREGVSIRDLRTVLETLADYGGLTKDPDTLTEFVRQGLGRSIVEQYKRDDDTLCLISLD
HHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEHH
RRVEEVVAEAIQPSDQGSYLAIEPNTAQLILSGIRQEMEKFNQIGTQPVLLASPSIRRHV
HHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHH
KKLTERFVPNLVVLSHNEVPSGIKIQSLGVVTLNAG
HHHHHHHCCCEEEEECCCCCCCCEEEEEEEEEECCC
>Mature Secondary Structure 
ANTAVDAVDLQPAKSNSDIYMAVALIGVLALMIIPLPAFLLDLFLAANITIALAILLVA
CCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYTQQPLDFSVFPSVLLVTTLFRLALNVAGTRLILLHGNEGVDAAGHVIKAFGQFVVGGN
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCC
YVVGAVIFLILVIINFVVITKGAGRVAEVAARFTLDAMPGKQMAIDADLSSGLINEKEAR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEECCHHCCCCCHHHHH
RRRSRVSREADFYGSMDGASKFVRGDAVAGILIMLVNIIGGFIIGVWQNGMPLEAALSNY
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCCCHHHHHCCC
TLLTIGEGLVAQIPALIISTAAGIIVTRSADEKNFGHEISGQFLNYPKAFYVSSGVLFAF
EEEEECCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHCCHHHCCCCHHHHCCHHHHHH
GLIPGLPHVAFFLLSGAAYMAGRLAKERAQVVEDDLMTLPAPAETGESGDQAGAIRPLDM
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
LELEVGYGLVPMVDAAQEGELLERIRSIRRQYAQKMGFVVPPVHIHDNLQLKPHEYNILI
HEECCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEECCCCEEEEE
KGAKVGGGEMIGQYLAMDSGAVSMPVEGVRTTEPVFGLPAIWIRPELKEQAQLAGYTVVD
EECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHCCEEEEC
STTIIATHISEIIRKHSHEMVGRQELQQLLDNLSSSFPKVVEDLVPNLLNLGTVLRVVRN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLREGVSIRDLRTVLETLADYGGLTKDPDTLTEFVRQGLGRSIVEQYKRDDDTLCLISLD
HHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEHH
RRVEEVVAEAIQPSDQGSYLAIEPNTAQLILSGIRQEMEKFNQIGTQPVLLASPSIRRHV
HHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHH
KKLTERFVPNLVVLSHNEVPSGIKIQSLGVVTLNAG
HHHHHHHCCCEEEEECCCCCCCCEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]