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The map label for this gene is flhF [H]

Identifier: 308513335

GI number: 308513335

Start: 3356313

End: 3357668

Strand: Reverse

Name: flhF [H]

Synonym: NA

Alternate gene names: 308513335

Gene position: 3357668-3356313 (Counterclockwise)

Preceding gene: 39998147

Following gene: 39998145

Centisome position: 88.03

GC content: 62.98

Gene sequence:

>1356_bases
ATGCTGGTTAAGACTTTCGAAGCGGTGGATATGTCCGAAGCCCTCCGGATGGTGAAGGCCGAACTGGGGCCCGACGCCAT
GATCATTTCTTCCAAGAAGGAGCGGAAGAAAGGTTTCCTCGGCTTCTTCAGCAAGCCCGTGATCAAGGTGACGGCGGCCC
TTGAGGTGAAGCCGCGCCAGCCGGCGCCCAATCCCTACCGGGAAGCCCAGGAGCAGCACCTCTCGGCCAAGGAGATGCTG
GAGAACTCCATGCTTGCCCCCCTGGCCCGCGAGCTGAAAGACCTGCGCCTGAAGGTGGAGCAGATGACGCGCCAGGAGGC
GGAGGCCAAGGCCAAGGCCGCCGAGGCGCAAAGTCGCGAGGAAAGTGCCGCAGCCGCAGAGGCTCCGGCTGCCCGTGAGT
TCAATCCGCGCTCCATCCCCAAGCAGGACCTGGAAGAGATGAAGAAGATCCTCTTCAAGACCCTGGCCGCAAAGGAAGCG
GGGGCGGAGCAGTCCGCCGAGAAAGCAGATGCAGATCCGGCGCCGGCCAAGGCACCTCAGACCGAAACCGAAAAGGCATC
TGGCGGCATCAAGGCGGCGCTCCGGGTGGTGGTGACCGAACTCCATCGCAAGGGGCTCGAGCGGGGCGCCATCAGGGCCG
TCATGGACCACCTGAAGCCGGAGGCCCGCAAGGGGGGGACCGTGGAGGCGATCCGTTCGTTCCTGCCCCAGGCATTCAAG
AGCGCCATCAAGTGCTCCGGCCCCCTGACCGTCAAAAAGAACGGCCCGCGGATCATCGCCCTGGTGGGACCGACAGGGGT
CGGCAAGACGACCACCATTGCCAAGCTGGCCGCCCACTATGCCCTGCGCGAAGGGCACCGGGCCGCCCTGATCACCATCG
ACAACTTCCGGGTGGGTGCCGTGGAGCAGTTGAAGACCTACTCGCGCATCATGGGCGTGCCGGTGGAGGTGGCTGCCACC
GCGGCTGAGTTGGAGGCGGCAATCGAGCTCCACTCCGACAAGGAGCTGATCCTGATCGATACGGCCGGCCGCAGCCACAA
GGACAGCGAGAAGATCGAAGAGCTCAAGGGGTTCCTGGAATCGCGCTTCGCCATTGAGATTCATCTCTGTCTGGCAGCCA
CCACCAGGGACCGTGAGGTGCTGGAAATAGTGGAGCGGTTCGGTGTACTGTCGGTTTCCCGCGTGATCTTCACCAAGCTG
GACGAGAGCGAGAGCTACGGCAGTATCGTTAACGCGCATCTGCGGACCAAATTCCCGCTTTCCTACTTCACCACCGGGCA
ACGGGTGCCCGAAGATCTTGAAATTGCAACTCCCGGCAGGCTTGCCGGGCTGGTTTTGGGGGAGAGTAAGCAATGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: flagellar biosynthetic protein FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:
NA

Sequences:

>Translated_451_residues
MLVKTFEAVDMSEALRMVKAELGPDAMIISSKKERKKGFLGFFSKPVIKVTAALEVKPRQPAPNPYREAQEQHLSAKEML
ENSMLAPLARELKDLRLKVEQMTRQEAEAKAKAAEAQSREESAAAAEAPAAREFNPRSIPKQDLEEMKKILFKTLAAKEA
GAEQSAEKADADPAPAKAPQTETEKASGGIKAALRVVVTELHRKGLERGAIRAVMDHLKPEARKGGTVEAIRSFLPQAFK
SAIKCSGPLTVKKNGPRIIALVGPTGVGKTTTIAKLAAHYALREGHRAALITIDNFRVGAVEQLKTYSRIMGVPVEVAAT
AAELEAAIELHSDKELILIDTAGRSHKDSEKIEELKGFLESRFAIEIHLCLAATTRDREVLEIVERFGVLSVSRVIFTKL
DESESYGSIVNAHLRTKFPLSYFTTGQRVPEDLEIATPGRLAGLVLGESKQ
>Mature_451_residues
MLVKTFEAVDMSEALRMVKAELGPDAMIISSKKERKKGFLGFFSKPVIKVTAALEVKPRQPAPNPYREAQEQHLSAKEML
ENSMLAPLARELKDLRLKVEQMTRQEAEAKAKAAEAQSREESAAAAEAPAAREFNPRSIPKQDLEEMKKILFKTLAAKEA
GAEQSAEKADADPAPAKAPQTETEKASGGIKAALRVVVTELHRKGLERGAIRAVMDHLKPEARKGGTVEAIRSFLPQAFK
SAIKCSGPLTVKKNGPRIIALVGPTGVGKTTTIAKLAAHYALREGHRAALITIDNFRVGAVEQLKTYSRIMGVPVEVAAT
AAELEAAIELHSDKELILIDTAGRSHKDSEKIEELKGFLESRFAIEIHLCLAATTRDREVLEIVERFGVLSVSRVIFTKL
DESESYGSIVNAHLRTKFPLSYFTTGQRVPEDLEIATPGRLAGLVLGESKQ

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI226371618, Length=210, Percent_Identity=31.9047619047619, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4507215, Length=210, Percent_Identity=31.9047619047619, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1789874, Length=202, Percent_Identity=31.6831683168317, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788963, Length=205, Percent_Identity=28.780487804878, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17539958, Length=226, Percent_Identity=30.5309734513274, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325345, Length=221, Percent_Identity=27.6018099547511, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI17647949, Length=238, Percent_Identity=26.890756302521, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 49225; Mature: 49225

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVKTFEAVDMSEALRMVKAELGPDAMIISSKKERKKGFLGFFSKPVIKVTAALEVKPRQ
CCCCCHHHCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCEEEEEEEEECCCC
PAPNPYREAQEQHLSAKEMLENSMLAPLARELKDLRLKVEQMTRQEAEAKAKAAEAQSRE
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESAAAAEAPAAREFNPRSIPKQDLEEMKKILFKTLAAKEAGAEQSAEKADADPAPAKAPQ
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCC
TETEKASGGIKAALRVVVTELHRKGLERGAIRAVMDHLKPEARKGGTVEAIRSFLPQAFK
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHH
SAIKCSGPLTVKKNGPRIIALVGPTGVGKTTTIAKLAAHYALREGHRAALITIDNFRVGA
HHHCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCH
VEQLKTYSRIMGVPVEVAATAAELEAAIELHSDKELILIDTAGRSHKDSEKIEELKGFLE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
SRFAIEIHLCLAATTRDREVLEIVERFGVLSVSRVIFTKLDESESYGSIVNAHLRTKFPL
CCEEEEEEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCH
SYFTTGQRVPEDLEIATPGRLAGLVLGESKQ
HHHCCCCCCCCCCEECCCCHHEEEEECCCCC
>Mature Secondary Structure
MLVKTFEAVDMSEALRMVKAELGPDAMIISSKKERKKGFLGFFSKPVIKVTAALEVKPRQ
CCCCCHHHCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCEEEEEEEEECCCC
PAPNPYREAQEQHLSAKEMLENSMLAPLARELKDLRLKVEQMTRQEAEAKAKAAEAQSRE
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESAAAAEAPAAREFNPRSIPKQDLEEMKKILFKTLAAKEAGAEQSAEKADADPAPAKAPQ
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCC
TETEKASGGIKAALRVVVTELHRKGLERGAIRAVMDHLKPEARKGGTVEAIRSFLPQAFK
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHH
SAIKCSGPLTVKKNGPRIIALVGPTGVGKTTTIAKLAAHYALREGHRAALITIDNFRVGA
HHHCCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCH
VEQLKTYSRIMGVPVEVAATAAELEAAIELHSDKELILIDTAGRSHKDSEKIEELKGFLE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
SRFAIEIHLCLAATTRDREVLEIVERFGVLSVSRVIFTKLDESESYGSIVNAHLRTKFPL
CCEEEEEEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCH
SYFTTGQRVPEDLEIATPGRLAGLVLGESKQ
HHHCCCCCCCCCCEECCCCHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]