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The map label for this gene is galE [H]

Identifier: 39997338

GI number: 39997338

Start: 2454686

End: 2455666

Strand: Reverse

Name: galE [H]

Synonym: GSU2240

Alternate gene names: 39997338

Gene position: 2455666-2454686 (Counterclockwise)

Preceding gene: 39997339

Following gene: 39997337

Centisome position: 64.38

GC content: 62.39

Gene sequence:

>981_bases
ATGCCTGTTCTGGTCACCGGCGGTGCCGGCTATATTGGAAGCCATGTGGTCCGCCAGCTCTCGGAGGCCGGCTATACGGT
GGTGGTCTACGACAATCTTTCCACTGGCTTCCCCGATGCCCTTGTCCACGGAGAACGGCTCGTGACGGGCGATTTGTCCG
ACACCGCCCGGCTCGACGCGCTTTTCGTGGAGTACGGTTTTTCAACGGTGCTCCACTTTGCCGCCTCCATCATTGCGCCC
GAGTCGGTCACAGCTCCGCTCAAGTATTACGGCAACAATACGCGAAATACCCTGAACCTCCTCGGTGCCTGCGTGAAGCA
CGGTGTCGAGCGTTTCATCTTCTCCAGCACCGCGGCGGTCTACGGTATCCCGGACAGCGGCGTCGCCGCCGAGGAGAGTG
CCACTGTGCCCATCAACCCCTACGGCACGTCAAAGCTCATGAGCGAGTGGATGCTGCGCGATGTCTGTGCCGCCCACGGC
ATGCGCTCGGTGGCCCTGCGCTACTTCAACGTGGCAGGCGCCGATCCCCAGGCACGCATGGGACAGAGAACGCCGGAGGC
GACCCACCTCATCAAGGTTTCCTGCCAGGCTGCCTTGGGGCTGCGGGACAAGGTGTGCATCTTCGGCACCGACTACCCGA
CTCCGGACGGCACCGGAATCCGGGATTACATCCACGTGGAGGATCTTGCCTCTGCTCATCTGGCCGCCCTGTCGTACCTG
GAAAAAGGTGGCGAGTCGACCCGTATCAATGTTGGCTATGGCAGCGGATCCAGTGTCCGGGAAGTGATCGACATGGTCCG
CCGGGTGTCGGGAGTTCATTTCCTTGCCGAGGAGGCTCCCCGGCGGCCGGGCGACCCACCCAGTCTCGTGGCACGGGCGG
ATCGAGCCAGGACGCTGCTCGGCTGGACTCCCCGCTACGATAATCTTGAAACCATCGTTGCCGATGCCTGGCGCTGGGAA
AAGAAAATCAGCGGCAACTAG

Upstream 100 bases:

>100_bases
GTGGGGTTCAAGCCGGCCACTCCCATCGGGGAGGGGATAGAGCGGTTCGTCGAGTGGTACCGGGGATACTACGGCGTCTG
ACGCCGTAAGAGGAGGACGT

Downstream 100 bases:

>100_bases
TGGCCGATTGTGGTGGCGCACGCGCTTCCCTTATCTTAGTTCACACAGATGGAGCATTCATGATCAAGAGCATGACGGGC
TACGGCAAGTCCGTGGTCGA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MPVLVTGGAGYIGSHVVRQLSEAGYTVVVYDNLSTGFPDALVHGERLVTGDLSDTARLDALFVEYGFSTVLHFAASIIAP
ESVTAPLKYYGNNTRNTLNLLGACVKHGVERFIFSSTAAVYGIPDSGVAAEESATVPINPYGTSKLMSEWMLRDVCAAHG
MRSVALRYFNVAGADPQARMGQRTPEATHLIKVSCQAALGLRDKVCIFGTDYPTPDGTGIRDYIHVEDLASAHLAALSYL
EKGGESTRINVGYGSGSSVREVIDMVRRVSGVHFLAEEAPRRPGDPPSLVARADRARTLLGWTPRYDNLETIVADAWRWE
KKISGN

Sequences:

>Translated_326_residues
MPVLVTGGAGYIGSHVVRQLSEAGYTVVVYDNLSTGFPDALVHGERLVTGDLSDTARLDALFVEYGFSTVLHFAASIIAP
ESVTAPLKYYGNNTRNTLNLLGACVKHGVERFIFSSTAAVYGIPDSGVAAEESATVPINPYGTSKLMSEWMLRDVCAAHG
MRSVALRYFNVAGADPQARMGQRTPEATHLIKVSCQAALGLRDKVCIFGTDYPTPDGTGIRDYIHVEDLASAHLAALSYL
EKGGESTRINVGYGSGSSVREVIDMVRRVSGVHFLAEEAPRRPGDPPSLVARADRARTLLGWTPRYDNLETIVADAWRWE
KKISGN
>Mature_325_residues
PVLVTGGAGYIGSHVVRQLSEAGYTVVVYDNLSTGFPDALVHGERLVTGDLSDTARLDALFVEYGFSTVLHFAASIIAPE
SVTAPLKYYGNNTRNTLNLLGACVKHGVERFIFSSTAAVYGIPDSGVAAEESATVPINPYGTSKLMSEWMLRDVCAAHGM
RSVALRYFNVAGADPQARMGQRTPEATHLIKVSCQAALGLRDKVCIFGTDYPTPDGTGIRDYIHVEDLASAHLAALSYLE
KGGESTRINVGYGSGSSVREVIDMVRRVSGVHFLAEEAPRRPGDPPSLVARADRARTLLGWTPRYDNLETIVADAWRWEK
KISGN

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=338, Percent_Identity=40.8284023668639, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI56118217, Length=338, Percent_Identity=40.8284023668639, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI189083684, Length=338, Percent_Identity=40.8284023668639, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI42516563, Length=311, Percent_Identity=26.0450160771704, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI7657641, Length=320, Percent_Identity=26.875, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI193211614, Length=252, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI8393516, Length=252, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1786974, Length=333, Percent_Identity=40.8408408408408, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI48994969, Length=299, Percent_Identity=29.4314381270903, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=344, Percent_Identity=38.953488372093, Blast_Score=209, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI71982038, Length=344, Percent_Identity=38.6627906976744, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI115532424, Length=348, Percent_Identity=25, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=310, Percent_Identity=24.5161290322581, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17568069, Length=246, Percent_Identity=28.4552845528455, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=337, Percent_Identity=40.6528189910979, Blast_Score=214, Evalue=1e-56,
Organism=Drosophila melanogaster, GI19923002, Length=339, Percent_Identity=37.1681415929204, Blast_Score=201, Evalue=5e-52,
Organism=Drosophila melanogaster, GI21356223, Length=309, Percent_Identity=24.9190938511327, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35193; Mature: 35062

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVLVTGGAGYIGSHVVRQLSEAGYTVVVYDNLSTGFPDALVHGERLVTGDLSDTARLDA
CCEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHCCCEEEECCCCCHHHHHH
LFVEYGFSTVLHFAASIIAPESVTAPLKYYGNNTRNTLNLLGACVKHGVERFIFSSTAAV
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
YGIPDSGVAAEESATVPINPYGTSKLMSEWMLRDVCAAHGMRSVALRYFNVAGADPQARM
EECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHH
GQRTPEATHLIKVSCQAALGLRDKVCIFGTDYPTPDGTGIRDYIHVEDLASAHLAALSYL
CCCCCCHHHEEEEEHHHHCCCCCCEEEEECCCCCCCCCCCHHHEEHHHHHHHHHHHHHHH
EKGGESTRINVGYGSGSSVREVIDMVRRVSGVHFLAEEAPRRPGDPPSLVARADRARTLL
HHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEE
GWTPRYDNLETIVADAWRWEKKISGN
CCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PVLVTGGAGYIGSHVVRQLSEAGYTVVVYDNLSTGFPDALVHGERLVTGDLSDTARLDA
CEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHCCCEEEECCCCCHHHHHH
LFVEYGFSTVLHFAASIIAPESVTAPLKYYGNNTRNTLNLLGACVKHGVERFIFSSTAAV
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
YGIPDSGVAAEESATVPINPYGTSKLMSEWMLRDVCAAHGMRSVALRYFNVAGADPQARM
EECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHH
GQRTPEATHLIKVSCQAALGLRDKVCIFGTDYPTPDGTGIRDYIHVEDLASAHLAALSYL
CCCCCCHHHEEEEEHHHHCCCCCCEEEEECCCCCCCCCCCHHHEEHHHHHHHHHHHHHHH
EKGGESTRINVGYGSGSSVREVIDMVRRVSGVHFLAEEAPRRPGDPPSLVARADRARTLL
HHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEE
GWTPRYDNLETIVADAWRWEKKISGN
CCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]