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The map label for this gene is gmhB [H]

Identifier: 39997182

GI number: 39997182

Start: 2290096

End: 2290671

Strand: Reverse

Name: gmhB [H]

Synonym: GSU2084

Alternate gene names: 39997182

Gene position: 2290671-2290096 (Counterclockwise)

Preceding gene: 39997183

Following gene: 39997181

Centisome position: 60.06

GC content: 63.54

Gene sequence:

>576_bases
GTGACGGGTGGCAGACGCGCTGTTTTTCTCGACCGTGACGGCACCATCAATGTTGAAAAGGGCTATGTCCACCAAGCCCA
TGAATTCGAGTTCGTCCCCGGAGCCCCCGAGGCGATCCGGCTCCTCAACGGAGCCGGTTTTCTCGTGGTGGTGGTGACCA
ACCAGTCGGGGGTTGCCCGCGGATACTACGACGAGGAGGCGGTGCACCGGCTCCATCGCTTCATGGATGCCGAACTGGCC
AAGGATGGTGCCTTCGTCGACGCCTACTACCTTTGTCCCCACCATCCCCACCACGGCGTGGGTCCCTACCGCATCGAGTG
CTCCTGCCGCAAGCCCCTGCCGGGGATGCTTACCGGCGCCGCTCGGGACATGGACATTGATCTGGCCCGTTCGTACCTGA
TAGGCGACAAGATGTCCGACGTGGAAGCGGGGTTGGCTGCGGGCTGTACCTCTCTGCTCGTCCTCACCGGGTACGGTGAT
GACGAGTGTCCCCGGGTCCCCGCCGGGGTCCTGGTCTGTGCCGACATCCTTGCCGCCACCCGCCGGGTTATTGAGCTGGA
GGGAGATAGCGTTTGA

Upstream 100 bases:

>100_bases
ATCCTACGGAGGGCGGGTGGAACTGGTGGCCTTCGTGGACGGTCGCTCCACGACGAACATCATCGAGAAGATTCTGAAGG
CCTACGGCGAGGAGTGACCG

Downstream 100 bases:

>100_bases
CGCTGTTTTGCCCGCTGTGCTATAACTACTGATTTAAAGAGATGTTTTCGGTGTCGAGGGCACTGAAGTTCAGGAGAGTC
CATGGCCATTTCCAAGGGAA

Product: HAD superfamily hydrolase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MTGGRRAVFLDRDGTINVEKGYVHQAHEFEFVPGAPEAIRLLNGAGFLVVVVTNQSGVARGYYDEEAVHRLHRFMDAELA
KDGAFVDAYYLCPHHPHHGVGPYRIECSCRKPLPGMLTGAARDMDIDLARSYLIGDKMSDVEAGLAAGCTSLLVLTGYGD
DECPRVPAGVLVCADILAATRRVIELEGDSV

Sequences:

>Translated_191_residues
MTGGRRAVFLDRDGTINVEKGYVHQAHEFEFVPGAPEAIRLLNGAGFLVVVVTNQSGVARGYYDEEAVHRLHRFMDAELA
KDGAFVDAYYLCPHHPHHGVGPYRIECSCRKPLPGMLTGAARDMDIDLARSYLIGDKMSDVEAGLAAGCTSLLVLTGYGD
DECPRVPAGVLVCADILAATRRVIELEGDSV
>Mature_190_residues
TGGRRAVFLDRDGTINVEKGYVHQAHEFEFVPGAPEAIRLLNGAGFLVVVVTNQSGVARGYYDEEAVHRLHRFMDAELAK
DGAFVDAYYLCPHHPHHGVGPYRIECSCRKPLPGMLTGAARDMDIDLARSYLIGDKMSDVEAGLAAGCTSLLVLTGYGDD
ECPRVPAGVLVCADILAATRRVIELEGDSV

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=158, Percent_Identity=49.3670886075949, Blast_Score=155, Evalue=1e-39,
Organism=Escherichia coli, GI87082027, Length=152, Percent_Identity=29.6052631578947, Blast_Score=74, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 20660; Mature: 20529

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGGRRAVFLDRDGTINVEKGYVHQAHEFEFVPGAPEAIRLLNGAGFLVVVVTNQSGVAR
CCCCCEEEEEECCCEEEECCCCEECCCEEEECCCCHHHHHHCCCCCEEEEEEECCCCCCC
GYYDEEAVHRLHRFMDAELAKDGAFVDAYYLCPHHPHHGVGPYRIECSCRKPLPGMLTGA
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCC
ARDMDIDLARSYLIGDKMSDVEAGLAAGCTSLLVLTGYGDDECPRVPAGVLVCADILAAT
CCCCCHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RRVIELEGDSV
HHEEEECCCCC
>Mature Secondary Structure 
TGGRRAVFLDRDGTINVEKGYVHQAHEFEFVPGAPEAIRLLNGAGFLVVVVTNQSGVAR
CCCCEEEEEECCCEEEECCCCEECCCEEEECCCCHHHHHHCCCCCEEEEEEECCCCCCC
GYYDEEAVHRLHRFMDAELAKDGAFVDAYYLCPHHPHHGVGPYRIECSCRKPLPGMLTGA
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCC
ARDMDIDLARSYLIGDKMSDVEAGLAAGCTSLLVLTGYGDDECPRVPAGVLVCADILAAT
CCCCCHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RRVIELEGDSV
HHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286; 12101286 [H]