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The map label for this gene is aroC

Identifier: 39997125

GI number: 39997125

Start: 2218709

End: 2219890

Strand: Reverse

Name: aroC

Synonym: GSU2027

Alternate gene names: 39997125

Gene position: 2219890-2218709 (Counterclockwise)

Preceding gene: 39997126

Following gene: 39997124

Centisome position: 58.2

GC content: 61.25

Gene sequence:

>1182_bases
ATGCTACGCTACCTGACCGCCGGTGAATCCCACGGCCCTCAACTTACGGCAATCATCGAGGGGCTGCCGGCAGGGCTGAA
AATTTCCGATGAATCAATTAATTGCGATCTTGCCCGGCGCCAGTGCGGCTACGGCCGCGGCGGCAGGATGAAGATCGAGC
GGGATGAGGCCCAGATACTCTCCGGAGTACGCTGGGGGGAGACGATCGGATCACCGGTGACGCTCTGCATCGTCAATCGC
GATTGGATCAACTGGCAGGAGAAGATGTCCCCCAATGCGCGGCATCGGGACGAGAAAATTCGCGTGACCCGCTCCCGCCC
CGGGCATGCGGATCTGCCGGGGGCCATGAAGTACGATCACCGGGACGTGCGCAACATCCTGGAACGTTCCAGCGCCCGCG
AGACTGCGGTGAGGGTGGCGGTTGGCGCTGTTGCCAAGGCGTTTCTCGCCTCGTTCGGCATTGAGGTGAACGGTTTTGTT
TCAGAGGTGGGGGGGATACGCGCCGAGCGCCGGTCGCTTCAGCTGGAGCGCATGAAAGAGCTGTCCGCCGCGTCCGAGCT
CTTTACCTATGATGCCGAGGCTGAAGAGCGGATGAAGGCCTTTATCGATGGCGCACGTGAGGCTGGCGACACGGTGGGTG
GAGTGGTTGAGATAATCGCCTCCGGCCTGCCCGTGGGGCTTGGCAGCCACGTGCAGTGGGATCGCAAGCTTGACGCCCGC
TTGGCCATGGCGGTCATGAGCATTCAGGCCATCAAGGGGGTGGAGATCGGGCTCGGTTTCGATGCCGCCCGCCGCCCCGG
CTCCCAGGTCCATGACGAAATCTACTATGACTCCACAAGAATAAGCCGAGGCGAACTTTCAGGTTTCTACCGCAAGAGCA
ATAATGCCGGCGGCATTGAAGGCGGTATCACCAACGGCGAGGATATCGTCATCCGCGCTGCCATGAAGCCGATTCCCACC
CTCTATCGGCCGCTCCGCTCCGTTGATATGCAGACCAAAGAGCCTTTTGAGGCTACGGTGGAGCGTTCCGATGTCTGTGC
CGTTCCCGCAGCGGCGGTGGTTGCAGAGGCTGTGGTGGCCCTTGAACTGGCCAATGCCATGCTGGAGAAGTTCGGCGGTG
ATTCGCTCGGGGAAGTACGGCGCAACTATGAGGGGTACCTGGAGTATGTCCGTGCCTTCTGA

Upstream 100 bases:

>100_bases
TCATAACGCCAAAAATTGTGAGCTGATACAACAAGATACAATATATACTACTTAACAAAAGCCAGGGTAATCCTGGCTTT
TGCGTGACAACGAGGAGACC

Downstream 100 bases:

>100_bases
CGGGCGCAACGTGGTCCTGACCGGTTTCATGGGAACCGGCAAGAGCACGGTGGGAAAGCTCCTGGCAAGGCGCCTCGGCT
ACCGCTTCAGTGACCTGGAT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MLRYLTAGESHGPQLTAIIEGLPAGLKISDESINCDLARRQCGYGRGGRMKIERDEAQILSGVRWGETIGSPVTLCIVNR
DWINWQEKMSPNARHRDEKIRVTRSRPGHADLPGAMKYDHRDVRNILERSSARETAVRVAVGAVAKAFLASFGIEVNGFV
SEVGGIRAERRSLQLERMKELSAASELFTYDAEAEERMKAFIDGAREAGDTVGGVVEIIASGLPVGLGSHVQWDRKLDAR
LAMAVMSIQAIKGVEIGLGFDAARRPGSQVHDEIYYDSTRISRGELSGFYRKSNNAGGIEGGITNGEDIVIRAAMKPIPT
LYRPLRSVDMQTKEPFEATVERSDVCAVPAAAVVAEAVVALELANAMLEKFGGDSLGEVRRNYEGYLEYVRAF

Sequences:

>Translated_393_residues
MLRYLTAGESHGPQLTAIIEGLPAGLKISDESINCDLARRQCGYGRGGRMKIERDEAQILSGVRWGETIGSPVTLCIVNR
DWINWQEKMSPNARHRDEKIRVTRSRPGHADLPGAMKYDHRDVRNILERSSARETAVRVAVGAVAKAFLASFGIEVNGFV
SEVGGIRAERRSLQLERMKELSAASELFTYDAEAEERMKAFIDGAREAGDTVGGVVEIIASGLPVGLGSHVQWDRKLDAR
LAMAVMSIQAIKGVEIGLGFDAARRPGSQVHDEIYYDSTRISRGELSGFYRKSNNAGGIEGGITNGEDIVIRAAMKPIPT
LYRPLRSVDMQTKEPFEATVERSDVCAVPAAAVVAEAVVALELANAMLEKFGGDSLGEVRRNYEGYLEYVRAF
>Mature_393_residues
MLRYLTAGESHGPQLTAIIEGLPAGLKISDESINCDLARRQCGYGRGGRMKIERDEAQILSGVRWGETIGSPVTLCIVNR
DWINWQEKMSPNARHRDEKIRVTRSRPGHADLPGAMKYDHRDVRNILERSSARETAVRVAVGAVAKAFLASFGIEVNGFV
SEVGGIRAERRSLQLERMKELSAASELFTYDAEAEERMKAFIDGAREAGDTVGGVVEIIASGLPVGLGSHVQWDRKLDAR
LAMAVMSIQAIKGVEIGLGFDAARRPGSQVHDEIYYDSTRISRGELSGFYRKSNNAGGIEGGITNGEDIVIRAAMKPIPT
LYRPLRSVDMQTKEPFEATVERSDVCAVPAAAVVAEAVVALELANAMLEKFGGDSLGEVRRNYEGYLEYVRAF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=372, Percent_Identity=38.1720430107527, Blast_Score=185, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6321290, Length=377, Percent_Identity=33.42175066313, Blast_Score=184, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_GEOSL (Q74BL4)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_953076.1
- ProteinModelPortal:   Q74BL4
- SMR:   Q74BL4
- GeneID:   2686091
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU2027
- NMPDR:   fig|243231.1.peg.2014
- TIGR:   GSU2027
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   GSUL243231:GSU_2027-MONOMER
- BRENDA:   4.2.3.5
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 43014; Mature: 43014

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRYLTAGESHGPQLTAIIEGLPAGLKISDESINCDLARRQCGYGRGGRMKIERDEAQIL
CCEEEECCCCCCCEEHHHHHCCCCCCEECCCCCCCHHHHHHCCCCCCCCEEEECHHHHHH
SGVRWGETIGSPVTLCIVNRDWINWQEKMSPNARHRDEKIRVTRSRPGHADLPGAMKYDH
HCCHHHHHCCCCEEEEEEECCCCCHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCH
RDVRNILERSSARETAVRVAVGAVAKAFLASFGIEVNGFVSEVGGIRAERRSLQLERMKE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHH
LSAASELFTYDAEAEERMKAFIDGAREAGDTVGGVVEIIASGLPVGLGSHVQWDRKLDAR
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LAMAVMSIQAIKGVEIGLGFDAARRPGSQVHDEIYYDSTRISRGELSGFYRKSNNAGGIE
HHHHHHHHHHHCCEEEECCCHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCC
GGITNGEDIVIRAAMKPIPTLYRPLRSVDMQTKEPFEATVERSDVCAVPAAAVVAEAVVA
CCCCCCCCEEEEEHHCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCHHCHHHHHHHHHHHH
LELANAMLEKFGGDSLGEVRRNYEGYLEYVRAF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLRYLTAGESHGPQLTAIIEGLPAGLKISDESINCDLARRQCGYGRGGRMKIERDEAQIL
CCEEEECCCCCCCEEHHHHHCCCCCCEECCCCCCCHHHHHHCCCCCCCCEEEECHHHHHH
SGVRWGETIGSPVTLCIVNRDWINWQEKMSPNARHRDEKIRVTRSRPGHADLPGAMKYDH
HCCHHHHHCCCCEEEEEEECCCCCHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCH
RDVRNILERSSARETAVRVAVGAVAKAFLASFGIEVNGFVSEVGGIRAERRSLQLERMKE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHH
LSAASELFTYDAEAEERMKAFIDGAREAGDTVGGVVEIIASGLPVGLGSHVQWDRKLDAR
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LAMAVMSIQAIKGVEIGLGFDAARRPGSQVHDEIYYDSTRISRGELSGFYRKSNNAGGIE
HHHHHHHHHHHCCEEEECCCHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCC
GGITNGEDIVIRAAMKPIPTLYRPLRSVDMQTKEPFEATVERSDVCAVPAAAVVAEAVVA
CCCCCCCCEEEEEHHCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCHHCHHHHHHHHHHHH
LELANAMLEKFGGDSLGEVRRNYEGYLEYVRAF
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA