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The map label for this gene is aroB

Identifier: 39997123

GI number: 39997123

Start: 2217113

End: 2218201

Strand: Reverse

Name: aroB

Synonym: GSU2025

Alternate gene names: 39997123

Gene position: 2218201-2217113 (Counterclockwise)

Preceding gene: 39997124

Following gene: 39997122

Centisome position: 58.16

GC content: 60.79

Gene sequence:

>1089_bases
ATGACCATCGAGACACTGAGAGTAGAACTCGGTGAACGGAGCTACGATATTCGCGTCGGCTCGGCGATCATCGGCACGAT
CGGCGCCGTGTGTCGTGACGCTGTGGCCGGCAGGCGCGTGGCCGTTGTGACCAATACCACCGTTGGTCCCCTCTATGCGG
ACGGTGTTGTTGATTCGTTGACCGCCGCCGGTTTTACCGTGCTTCGCATTGATATCCCCGATGGAGAAGAGCATAAAACT
TCTGTCACCCTCACTAGTGTCTATGACGAACTCATCAAAGGCGGATTGACGCGGGACTCTCTTCTTGTTGCCCTTGGCGG
AGGGGTGGTTGGAGACCTGGCCGGTTATGCCGCTGCCACGTATCTGCGCGGTGTTCCCTTCGTGCAGGTCCCGACCACGC
TCCTCGCTCAGGTGGATAGCAGCGTGGGCGGCAAGACCGGCATCAACCATCCACTGGGCAAGAATCTGATCGGCGCGTTC
CATCAGCCCAGAGCGGTTCTCATTGACGTGGACACCCTTGCAACTCTCCCCCAGCGTGAGTATCTCGGCGGCCTTGCCGA
AGTCATCAAATATGGCGTGGTGCTCGACGGAAAGTTCTTCGCGTTTCTCGAACAGAATGTGAGCGCTCTTCTCGGGCGAG
ACCGGCAGACGTTGGTCCGTGCCATTACGCGTTGCTGTGCGCTGAAGGCCTGGGTCGTGGAGCAGGATGAACGCGAGACC
GGACTTCGGGCGGTCCTCAACTACGGGCACACGTTCGGCCACGCCGTGGAGGCGCTGACGGGCTACACTGCCGTTCTCCA
CGGGGAGGCGGTCGCCATTGGCATGGTCCGGGCCGCTGTCCTGGCAGAGGCCCGGGGGCACTCTTCGGCCGGAGATACCC
GACGGATTCGCGCACTTGTGGAGGCCTTGGGGCTGCCGACCGAACTCCCGTCGTTTGATGCAGACAGCTACCGGGATGTA
CTTCTGCGCGATAAGAAGGCTCGGGATCGCGGGCTGGACTTCGTACTCAACCGGGGAATAGGCGGCCATGAGATCGTCAG
GATCGAAAACCTGTCTGAAGTATTCGGCATCTGCGGCGTGGGGGAATGA

Upstream 100 bases:

>100_bases
GTGAGAACGCTTACGCCGATGCGGACTTGAGGATTGACACTGCCGGCAAAAGCGTGGAAGATGTGGTCACAGAAATCGCC
ACCTTTGTCCGGGAGCATCA

Downstream 100 bases:

>100_bases
CCATGGAACACGGAACCGAATCGTTCTGGACCGACATCAAGCGCTATGAGGATATCCTGGCCAAAGATCCCGGATCGTAC
TGCTTTGCGCCTCTTTCTGA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MTIETLRVELGERSYDIRVGSAIIGTIGAVCRDAVAGRRVAVVTNTTVGPLYADGVVDSLTAAGFTVLRIDIPDGEEHKT
SVTLTSVYDELIKGGLTRDSLLVALGGGVVGDLAGYAAATYLRGVPFVQVPTTLLAQVDSSVGGKTGINHPLGKNLIGAF
HQPRAVLIDVDTLATLPQREYLGGLAEVIKYGVVLDGKFFAFLEQNVSALLGRDRQTLVRAITRCCALKAWVVEQDERET
GLRAVLNYGHTFGHAVEALTGYTAVLHGEAVAIGMVRAAVLAEARGHSSAGDTRRIRALVEALGLPTELPSFDADSYRDV
LLRDKKARDRGLDFVLNRGIGGHEIVRIENLSEVFGICGVGE

Sequences:

>Translated_362_residues
MTIETLRVELGERSYDIRVGSAIIGTIGAVCRDAVAGRRVAVVTNTTVGPLYADGVVDSLTAAGFTVLRIDIPDGEEHKT
SVTLTSVYDELIKGGLTRDSLLVALGGGVVGDLAGYAAATYLRGVPFVQVPTTLLAQVDSSVGGKTGINHPLGKNLIGAF
HQPRAVLIDVDTLATLPQREYLGGLAEVIKYGVVLDGKFFAFLEQNVSALLGRDRQTLVRAITRCCALKAWVVEQDERET
GLRAVLNYGHTFGHAVEALTGYTAVLHGEAVAIGMVRAAVLAEARGHSSAGDTRRIRALVEALGLPTELPSFDADSYRDV
LLRDKKARDRGLDFVLNRGIGGHEIVRIENLSEVFGICGVGE
>Mature_361_residues
TIETLRVELGERSYDIRVGSAIIGTIGAVCRDAVAGRRVAVVTNTTVGPLYADGVVDSLTAAGFTVLRIDIPDGEEHKTS
VTLTSVYDELIKGGLTRDSLLVALGGGVVGDLAGYAAATYLRGVPFVQVPTTLLAQVDSSVGGKTGINHPLGKNLIGAFH
QPRAVLIDVDTLATLPQREYLGGLAEVIKYGVVLDGKFFAFLEQNVSALLGRDRQTLVRAITRCCALKAWVVEQDERETG
LRAVLNYGHTFGHAVEALTGYTAVLHGEAVAIGMVRAAVLAEARGHSSAGDTRRIRALVEALGLPTELPSFDADSYRDVL
LRDKKARDRGLDFVLNRGIGGHEIVRIENLSEVFGICGVGE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=344, Percent_Identity=52.6162790697674, Blast_Score=323, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6320332, Length=315, Percent_Identity=39.0476190476191, Blast_Score=202, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_GEOSL (Q74BL6)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_953074.1
- ProteinModelPortal:   Q74BL6
- SMR:   Q74BL6
- GeneID:   2686097
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU2025
- NMPDR:   fig|243231.1.peg.2012
- TIGR:   GSU2025
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- ProtClustDB:   PRK00002
- BioCyc:   GSUL243231:GSU_2025-MONOMER
- BRENDA:   4.2.3.4
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 38489; Mature: 38357

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIETLRVELGERSYDIRVGSAIIGTIGAVCRDAVAGRRVAVVTNTTVGPLYADGVVDSL
CCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHH
TAAGFTVLRIDIPDGEEHKTSVTLTSVYDELIKGGLTRDSLLVALGGGVVGDLAGYAAAT
HHCCEEEEEEECCCCCCCCCEEEHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHH
YLRGVPFVQVPTTLLAQVDSSVGGKTGINHPLGKNLIGAFHQPRAVLIDVDTLATLPQRE
HHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCEEEEECHHHHCCCCHH
YLGGLAEVIKYGVVLDGKFFAFLEQNVSALLGRDRQTLVRAITRCCALKAWVVEQDERET
HHHHHHHHHHHCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
GLRAVLNYGHTFGHAVEALTGYTAVLHGEAVAIGMVRAAVLAEARGHSSAGDTRRIRALV
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
EALGLPTELPSFDADSYRDVLLRDKKARDRGLDFVLNRGIGGHEIVRIENLSEVFGICGV
HHHCCCCCCCCCCCCHHHHHHHHCHHHHHCCCHHEEECCCCCCEEEEECCHHHHHHHCCC
GE
CC
>Mature Secondary Structure 
TIETLRVELGERSYDIRVGSAIIGTIGAVCRDAVAGRRVAVVTNTTVGPLYADGVVDSL
CCEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHH
TAAGFTVLRIDIPDGEEHKTSVTLTSVYDELIKGGLTRDSLLVALGGGVVGDLAGYAAAT
HHCCEEEEEEECCCCCCCCCEEEHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHH
YLRGVPFVQVPTTLLAQVDSSVGGKTGINHPLGKNLIGAFHQPRAVLIDVDTLATLPQRE
HHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCEEEEECHHHHCCCCHH
YLGGLAEVIKYGVVLDGKFFAFLEQNVSALLGRDRQTLVRAITRCCALKAWVVEQDERET
HHHHHHHHHHHCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
GLRAVLNYGHTFGHAVEALTGYTAVLHGEAVAIGMVRAAVLAEARGHSSAGDTRRIRALV
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
EALGLPTELPSFDADSYRDVLLRDKKARDRGLDFVLNRGIGGHEIVRIENLSEVFGICGV
HHHCCCCCCCCCCCCHHHHHHHHCHHHHHCCCHHEEECCCCCCEEEEECCHHHHHHHCCC
GE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA