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The map label for this gene is kdsC [H]

Identifier: 39996990

GI number: 39996990

Start: 2069876

End: 2070415

Strand: Reverse

Name: kdsC [H]

Synonym: GSU1892

Alternate gene names: 39996990

Gene position: 2070415-2069876 (Counterclockwise)

Preceding gene: 39996991

Following gene: 39996989

Centisome position: 54.28

GC content: 59.44

Gene sequence:

>540_bases
ATGACCGCCGGGGAAAAGGAACTCATGGACGGACGCCTTGCCGGGATCAAGTTGCTGTTGCTCGATGTGGACGGCGTCAT
GACCGATGGCCGGATCATCTTCGACTCCAATGGAGTTGAGAGCAAGTTCTTCAATGTCAAGGACGGTCACGGCATCAAGA
TGATTCAGCGGGCCGGTATCCAGGTGGGGATCATTTCGGGTCGCCAGTCGGTGGTGGTTGCCAACCGGGCTGCTGAGCTG
GATATCCCGATACTCTATCAAAAAGCCATCGACAAGCTGACACCGTACGGGGAGATTCTCGCCGCCACCGGCCTGGAGGA
CTCACAGGTCGCCTTTGTGGGTGATGATGTGATCGATATTCCGGTGCTGCGGCGCGTCGGGTTCGCCGCCGCACCTGCCG
ATGCCGTACCGGAAGTACTGCCGTTTGTGCATTTCACCACCCGCAATCGTGGCGGGTGGGGAGCCGTCCGCGAAGTCTGC
GATCTCCTTCTCAGGGCCCAGGGAAAGTGGGACGAGATTACCGCGCGCTATTACCGCTAG

Upstream 100 bases:

>100_bases
AGTCCCACTCCATAACGTCTCTGTTCGTTTTTGACGATACGGCCGACAACCGGCCGGTGGGAGTCATTCATCTCCATGAC
CTGTTGCGGGCGGGGTTGGC

Downstream 100 bases:

>100_bases
AGCGGTATTCATCATGTTCTTCTCCTGAAGCTCACCCTTCAGTATCCCTGCGCCTAAAGCCCCGTCTGTTTTGTCCGAAA
AGAGAGTATCTCCCTTCATC

Product: YrbI family phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MTAGEKELMDGRLAGIKLLLLDVDGVMTDGRIIFDSNGVESKFFNVKDGHGIKMIQRAGIQVGIISGRQSVVVANRAAEL
DIPILYQKAIDKLTPYGEILAATGLEDSQVAFVGDDVIDIPVLRRVGFAAAPADAVPEVLPFVHFTTRNRGGWGAVREVC
DLLLRAQGKWDEITARYYR

Sequences:

>Translated_179_residues
MTAGEKELMDGRLAGIKLLLLDVDGVMTDGRIIFDSNGVESKFFNVKDGHGIKMIQRAGIQVGIISGRQSVVVANRAAEL
DIPILYQKAIDKLTPYGEILAATGLEDSQVAFVGDDVIDIPVLRRVGFAAAPADAVPEVLPFVHFTTRNRGGWGAVREVC
DLLLRAQGKWDEITARYYR
>Mature_178_residues
TAGEKELMDGRLAGIKLLLLDVDGVMTDGRIIFDSNGVESKFFNVKDGHGIKMIQRAGIQVGIISGRQSVVVANRAAELD
IPILYQKAIDKLTPYGEILAATGLEDSQVAFVGDDVIDIPVLRRVGFAAAPADAVPEVLPFVHFTTRNRGGWGAVREVCD
LLLRAQGKWDEITARYYR

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=147, Percent_Identity=34.6938775510204, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI2367202, Length=157, Percent_Identity=50.3184713375796, Blast_Score=152, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19527; Mature: 19396

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAGEKELMDGRLAGIKLLLLDVDGVMTDGRIIFDSNGVESKFFNVKDGHGIKMIQRAGI
CCCCHHHHHCCHHCCEEEEEEECCCEEECCEEEECCCCCCCEEEECCCCCCHHHHHHCCC
QVGIISGRQSVVVANRAAELDIPILYQKAIDKLTPYGEILAATGLEDSQVAFVGDDVIDI
EEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCHHEEECCCCCCEEEEECCCEECH
PVLRRVGFAAAPADAVPEVLPFVHFTTRNRGGWGAVREVCDLLLRAQGKWDEITARYYR
HHHHHCCCCCCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCC
>Mature Secondary Structure 
TAGEKELMDGRLAGIKLLLLDVDGVMTDGRIIFDSNGVESKFFNVKDGHGIKMIQRAGI
CCCHHHHHCCHHCCEEEEEEECCCEEECCEEEECCCCCCCEEEECCCCCCHHHHHHCCC
QVGIISGRQSVVVANRAAELDIPILYQKAIDKLTPYGEILAATGLEDSQVAFVGDDVIDI
EEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCHHEEECCCCCCEEEEECCCEECH
PVLRRVGFAAAPADAVPEVLPFVHFTTRNRGGWGAVREVCDLLLRAQGKWDEITARYYR
HHHHHCCCCCCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]