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The map label for this gene is xerD [H]

Identifier: 39996918

GI number: 39996918

Start: 1984912

End: 1985799

Strand: Reverse

Name: xerD [H]

Synonym: GSU1819

Alternate gene names: 39996918

Gene position: 1985799-1984912 (Counterclockwise)

Preceding gene: 39996919

Following gene: 39996917

Centisome position: 52.06

GC content: 60.25

Gene sequence:

>888_bases
ATGAATCAGCATCTGGATCTTTTTCTCGGCTATCTGGTGGTCGAGAAGGGGCTTGCCCGCAATTCGGTGGAGTCCTATGC
CAGGGACCTGAGCCGTTATCTGGGGTATGTCGAGCAGCACGCGGGAGGTGATCCTGCCGCAATCCGCCCCCTCCATGTTG
CGGATTTCCTGGCGCACCTCAAGGAGTCGGGACTCGGCGCCAGAAGCCGTGCCCGCGCCCTGTCCGCAGTACGGATGTTT
CACCGTTTCCTGCTGGTGGAAGGGTATGCCGAAACCAATCCCACCAGCATTATTGAAGCGCCCCGCGTTCTCGCCAAGCT
GCCCCAGGTCCTGACCGGCCGGGAGGTGGAGATGCTTCTGGCCGCGCCGGCCGGTGATGCCCCCATCGAGGTGCGTGACC
GGGCCATGCTGGAGCTTCTCTATGCAACGGGTCTCCGGGTTTCCGAACTGGTGGGGCTGCGCACGAGGGATGTGAATACC
TCAGCCGGTTACCTAATGACCGTGGGCAAGGGGGAAAAAGAGCGGCTGGTCCCCATGGGCGAATCAGCCTGTGCAGCCGT
AGTGCTCTATCTTTCCTCGGCTAGGATTCAACTGGGTCGGGGCGGGGAGAGTCCCTTTCTTTTCCTGAGCAGGCTCGGTG
AACGGATGACTCGCCAGGCCTTTTGGAATATAATAAAAAAGCGCTCAAGGCAGGCCGGCATTCTGAAGGGAATTTCGCCC
CACACGCTCAGGCATTCGTTCGCCACCCATCTGCTCGAAAACGGGGCGGACCTACGGAGCGTGCAGGCCATGCTCGGCCA
TGCGGATCTCTCAACAACCCAGATTTATACGCATGTTACCCGTGAACGGCTGAAGCGTCTGCACGAACAATTCCACCCGC
GCGGCTGA

Upstream 100 bases:

>100_bases
ACGTCTTTTACGTGAAGGATATCTTTGGCCACAAGATCACCAGTGTCGAGCGGCTGGAGGAGATCCGGGAAAAGCTCCGT
GTCGCGGTTGAACAGCCGGA

Downstream 100 bases:

>100_bases
AACGTCGGCCAGGGGGCGGAGATGATAACGTGAAGTGAAATCGTGATCCTGTGATGAAAGGAACTGGCATGAAGTACATT
GTGTTACTCGGAGATGGCAT

Product: integrase/recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNQHLDLFLGYLVVEKGLARNSVESYARDLSRYLGYVEQHAGGDPAAIRPLHVADFLAHLKESGLGARSRARALSAVRMF
HRFLLVEGYAETNPTSIIEAPRVLAKLPQVLTGREVEMLLAAPAGDAPIEVRDRAMLELLYATGLRVSELVGLRTRDVNT
SAGYLMTVGKGEKERLVPMGESACAAVVLYLSSARIQLGRGGESPFLFLSRLGERMTRQAFWNIIKKRSRQAGILKGISP
HTLRHSFATHLLENGADLRSVQAMLGHADLSTTQIYTHVTRERLKRLHEQFHPRG

Sequences:

>Translated_295_residues
MNQHLDLFLGYLVVEKGLARNSVESYARDLSRYLGYVEQHAGGDPAAIRPLHVADFLAHLKESGLGARSRARALSAVRMF
HRFLLVEGYAETNPTSIIEAPRVLAKLPQVLTGREVEMLLAAPAGDAPIEVRDRAMLELLYATGLRVSELVGLRTRDVNT
SAGYLMTVGKGEKERLVPMGESACAAVVLYLSSARIQLGRGGESPFLFLSRLGERMTRQAFWNIIKKRSRQAGILKGISP
HTLRHSFATHLLENGADLRSVQAMLGHADLSTTQIYTHVTRERLKRLHEQFHPRG
>Mature_295_residues
MNQHLDLFLGYLVVEKGLARNSVESYARDLSRYLGYVEQHAGGDPAAIRPLHVADFLAHLKESGLGARSRARALSAVRMF
HRFLLVEGYAETNPTSIIEAPRVLAKLPQVLTGREVEMLLAAPAGDAPIEVRDRAMLELLYATGLRVSELVGLRTRDVNT
SAGYLMTVGKGEKERLVPMGESACAAVVLYLSSARIQLGRGGESPFLFLSRLGERMTRQAFWNIIKKRSRQAGILKGISP
HTLRHSFATHLLENGADLRSVQAMLGHADLSTTQIYTHVTRERLKRLHEQFHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=48.2876712328767, Blast_Score=255, Evalue=2e-69,
Organism=Escherichia coli, GI1790244, Length=298, Percent_Identity=37.9194630872483, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1790767, Length=174, Percent_Identity=34.4827586206897, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1790768, Length=181, Percent_Identity=30.939226519337, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 32726; Mature: 32726

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQHLDLFLGYLVVEKGLARNSVESYARDLSRYLGYVEQHAGGDPAAIRPLHVADFLAHL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
KESGLGARSRARALSAVRMFHRFLLVEGYAETNPTSIIEAPRVLAKLPQVLTGREVEMLL
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
AAPAGDAPIEVRDRAMLELLYATGLRVSELVGLRTRDVNTSAGYLMTVGKGEKERLVPMG
ECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCEEEEECCCCHHCCCCCC
ESACAAVVLYLSSARIQLGRGGESPFLFLSRLGERMTRQAFWNIIKKRSRQAGILKGISP
HHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
HTLRHSFATHLLENGADLRSVQAMLGHADLSTTQIYTHVTRERLKRLHEQFHPRG
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNQHLDLFLGYLVVEKGLARNSVESYARDLSRYLGYVEQHAGGDPAAIRPLHVADFLAHL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
KESGLGARSRARALSAVRMFHRFLLVEGYAETNPTSIIEAPRVLAKLPQVLTGREVEMLL
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
AAPAGDAPIEVRDRAMLELLYATGLRVSELVGLRTRDVNTSAGYLMTVGKGEKERLVPMG
ECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCEEEEECCCCHHCCCCCC
ESACAAVVLYLSSARIQLGRGGESPFLFLSRLGERMTRQAFWNIIKKRSRQAGILKGISP
HHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
HTLRHSFATHLLENGADLRSVQAMLGHADLSTTQIYTHVTRERLKRLHEQFHPRG
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10537218; 10498718 [H]