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The map label for this gene is cobO [H]

Identifier: 39996677

GI number: 39996677

Start: 1729228

End: 1729758

Strand: Direct

Name: cobO [H]

Synonym: GSU1577

Alternate gene names: 39996677

Gene position: 1729228-1729758 (Clockwise)

Preceding gene: 39996676

Following gene: 39996678

Centisome position: 45.34

GC content: 61.96

Gene sequence:

>531_bases
ATGAAGCTCGACCAGGGATGTATCCAGGTGTACACCGGCAACGGCAAGGGCAAGACCACGGCGGCATTGGGGCTTGCCTT
CCGGGCGGCGGGACGAGGATTTCAGGTTCTCGTCATCCAGTTCATGAAGGGAGGGGGCCCCTACGGCGAGCACGAGGCGG
CCAAGCGTCTGGCCCCGGAGCTGACCATCATCGCCACCGGCCGGCCGGGCTGGGTGAATCGTGAGAACCCCGACCCTGAA
GATGTACGTCTTGCCCGCGAGGCGCTCAATATGGCTCGTGAGGCGCTGACCAGGGAGCACTACGATCTGGTGATCCTCGA
CGAAATCAACGGCGCCGTCTCGTTCGGCCTCATTCCGGTTGATGACGTTCTGGAACTGATGACCCTGAAGCCACCCCGGG
TGGAACTGGTCCTCACAGGGCGCAATGCCGATGAACGGGTCATCGCCGCCGCCGATCTGGTCACCGAGATGCGTGAGATC
AAGCACTATTACCGTGCCGGCGTACCGGCACGTACGGGAATCGAAAAATAA

Upstream 100 bases:

>100_bases
AGAATAAAACGGGAGGCGGTTTTGATGGACGGCTTGGCTGCTCTGCCATGATGGTGGCGGATTACGACCCGGGTGTCCGG
CCTCCGCAGGAACGAATCCA

Downstream 100 bases:

>100_bases
AGGAGATGGTCATGACTGAAAGAACGCTGCGTATTCTCGTTGGCAAGCCGGGGCTCGACGGCCATGACAGGGGTGCCAAG
GTAGTGGCCCGGGCCTTCCG

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MKLDQGCIQVYTGNGKGKTTAALGLAFRAAGRGFQVLVIQFMKGGGPYGEHEAAKRLAPELTIIATGRPGWVNRENPDPE
DVRLAREALNMAREALTREHYDLVILDEINGAVSFGLIPVDDVLELMTLKPPRVELVLTGRNADERVIAAADLVTEMREI
KHYYRAGVPARTGIEK

Sequences:

>Translated_176_residues
MKLDQGCIQVYTGNGKGKTTAALGLAFRAAGRGFQVLVIQFMKGGGPYGEHEAAKRLAPELTIIATGRPGWVNRENPDPE
DVRLAREALNMAREALTREHYDLVILDEINGAVSFGLIPVDDVLELMTLKPPRVELVLTGRNADERVIAAADLVTEMREI
KHYYRAGVPARTGIEK
>Mature_176_residues
MKLDQGCIQVYTGNGKGKTTAALGLAFRAAGRGFQVLVIQFMKGGGPYGEHEAAKRLAPELTIIATGRPGWVNRENPDPE
DVRLAREALNMAREALTREHYDLVILDEINGAVSFGLIPVDDVLELMTLKPPRVELVLTGRNADERVIAAADLVTEMREI
KHYYRAGVPARTGIEK

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=174, Percent_Identity=38.5057471264368, Blast_Score=120, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 19295; Mature: 19295

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDQGCIQVYTGNGKGKTTAALGLAFRAAGRGFQVLVIQFMKGGGPYGEHEAAKRLAPE
CCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHEEHHHCCCCCCHHHHHHHCCCC
LTIIATGRPGWVNRENPDPEDVRLAREALNMAREALTREHYDLVILDEINGAVSFGLIPV
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCH
DDVLELMTLKPPRVELVLTGRNADERVIAAADLVTEMREIKHYYRAGVPARTGIEK
HHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKLDQGCIQVYTGNGKGKTTAALGLAFRAAGRGFQVLVIQFMKGGGPYGEHEAAKRLAPE
CCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHEEHHHCCCCCCHHHHHHHCCCC
LTIIATGRPGWVNRENPDPEDVRLAREALNMAREALTREHYDLVILDEINGAVSFGLIPV
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCH
DDVLELMTLKPPRVELVLTGRNADERVIAAADLVTEMREIKHYYRAGVPARTGIEK
HHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]