BacMap

Definition	Geobacter sulfurreducens PCA chromosome, complete genome.
Accession	NC_002939
Length	3,814,139

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The map label for this gene is ucpA [C]

Identifier: 39996676

GI number: 39996676

Start: 1727617

End: 1728423

Strand: Direct

Name: ucpA [C]

Synonym: GSU1576

Alternate gene names: 39996676

Gene position: 1727617-1728423 (Clockwise)

Preceding gene: 39996675

Following gene: 39996677

Centisome position: 45.3

GC content: 58.98

Gene sequence:

>807_bases
ATGAGAAGACTTGAAGGCAAGATTGCGCTGGTCACCGGCGCGGCAAGGGGGATAGGGGAGGCGATTGCCCGTGCCTTCGC
AACCGCCGGGGCATTTGTCTATCTGACAGACATCAATGATGCACAGGGAGCGGTCGTTGCCGGACAAATAGGAGCGGAAG
CGGCCTATCGCCGCCTGGATGTCCGGGAGGAGGCTGACTGGCAGTGTGTCACCACGGAGATTACCGGCCGGCATGGCAGG
CTCGATATTGTGGTCAATAACGCGGGGATAACCGGCTTTGAGGACGGAATGGTCGCGCACGACCCTGAGCATGCCAGTTT
GGACAGTTGGCATGCAGTACATCGGACCAATCTCGACGGTGTCTTTCTAGGATGCAAATATGCCATCCAGGAAATGCGCA
GAACAGGTACCGGGTCGATCATCAATATTTCGTCGCGTTCCGGGTTGGTCGGCATACCCGCCGCTGCCGCCTATGCGTCG
TCCAAGGCTGCTGTGCGCAACCACACCAAAACGGTCGCACTCTATTGCGCGGATCAGGGCCTTGCCATTCGCTGCAACTC
TCTGCACCCTGCCGCAATTCTCACCCCCATGTGGGAACCCCTCATTGGGCCGCCGGGGGCGGAGCGGGAGCAACGGATGA
AGGAATTCGTTTGGGATACGCCGCTCAGGAGGTTCGGTACTCCGGAGGAGATTGCCGCAGTGGCTCTCCTGTTGGCCTCG
GACGAGGTCACATACATGACCGGCAGCGAAATAACCATTGACGGAGGAATCCTTGCTGGTTCGGTGGCAAGGCCGAGTGT
AGATTAG

Upstream 100 bases:

>100_bases
TGGGCAACGGGGCCTGCAGGTCTGCACAGAGCCCGGCCAGCGCGGGATGGTGCGCATCGTGGCGCGGAAAATCTGATTAG
AATACTCAATAGAGGAGATC

Downstream 100 bases:

>100_bases
CCCGTTACCTGGTATCGTGAAGATGTTTTATGGTTTGGTTGGCCAGTTTCGCCTCGACAGACTGGAGTATTCAACATGCT
TTCCCCTGTTTCTGGGGACA

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MRRLEGKIALVTGAARGIGEAIARAFATAGAFVYLTDINDAQGAVVAGQIGAEAAYRRLDVREEADWQCVTTEITGRHGR
LDIVVNNAGITGFEDGMVAHDPEHASLDSWHAVHRTNLDGVFLGCKYAIQEMRRTGTGSIINISSRSGLVGIPAAAAYAS
SKAAVRNHTKTVALYCADQGLAIRCNSLHPAAILTPMWEPLIGPPGAEREQRMKEFVWDTPLRRFGTPEEIAAVALLLAS
DEVTYMTGSEITIDGGILAGSVARPSVD

Sequences:

>Translated_268_residues
MRRLEGKIALVTGAARGIGEAIARAFATAGAFVYLTDINDAQGAVVAGQIGAEAAYRRLDVREEADWQCVTTEITGRHGR
LDIVVNNAGITGFEDGMVAHDPEHASLDSWHAVHRTNLDGVFLGCKYAIQEMRRTGTGSIINISSRSGLVGIPAAAAYAS
SKAAVRNHTKTVALYCADQGLAIRCNSLHPAAILTPMWEPLIGPPGAEREQRMKEFVWDTPLRRFGTPEEIAAVALLLAS
DEVTYMTGSEITIDGGILAGSVARPSVD
>Mature_268_residues
MRRLEGKIALVTGAARGIGEAIARAFATAGAFVYLTDINDAQGAVVAGQIGAEAAYRRLDVREEADWQCVTTEITGRHGR
LDIVVNNAGITGFEDGMVAHDPEHASLDSWHAVHRTNLDGVFLGCKYAIQEMRRTGTGSIINISSRSGLVGIPAAAAYAS
SKAAVRNHTKTVALYCADQGLAIRCNSLHPAAILTPMWEPLIGPPGAEREQRMKEFVWDTPLRRFGTPEEIAAVALLLAS
DEVTYMTGSEITIDGGILAGSVARPSVD

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=34.468085106383, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI15277342, Length=269, Percent_Identity=34.2007434944238, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=36.1867704280156, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=29.5019157088123, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=31.7460317460317, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=30.3501945525292, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI31542939, Length=224, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4758504, Length=263, Percent_Identity=28.5171102661597, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=28.0155642023346, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI4504505, Length=201, Percent_Identity=31.8407960199005, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI83715985, Length=263, Percent_Identity=27.7566539923954, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI224922801, Length=180, Percent_Identity=30.5555555555556, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI10190704, Length=261, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI7705925, Length=258, Percent_Identity=26.3565891472868, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI142976729, Length=214, Percent_Identity=27.1028037383178, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4503301, Length=258, Percent_Identity=25.968992248062, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=35.632183908046, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=35.4330708661417, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=35.0194552529183, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788459, Length=259, Percent_Identity=30.5019305019305, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=35.408560311284, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1786812, Length=262, Percent_Identity=32.4427480916031, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=28.6821705426357, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=27.5193798449612, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1789208, Length=262, Percent_Identity=30.1526717557252, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367365, Length=258, Percent_Identity=30.2325581395349, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789378, Length=259, Percent_Identity=29.3436293436293, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=27.9693486590038, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787526, Length=257, Percent_Identity=27.2373540856031, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787820, Length=187, Percent_Identity=28.8770053475936, Blast_Score=68, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=32.8125, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=33.7209302325581, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=30.4832713754647, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=264, Percent_Identity=28.4090909090909, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=32.4817518248175, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=273, Percent_Identity=29.6703296703297, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=30, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=275, Percent_Identity=28.7272727272727, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=266, Percent_Identity=27.8195488721804, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=279, Percent_Identity=28.673835125448, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=30, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=27.037037037037, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=275, Percent_Identity=29.8181818181818, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=275, Percent_Identity=30.1818181818182, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=264, Percent_Identity=31.4393939393939, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=30.7407407407407, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=272, Percent_Identity=29.0441176470588, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=276, Percent_Identity=27.1739130434783, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=29.2490118577075, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=261, Percent_Identity=27.9693486590038, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=264, Percent_Identity=29.5454545454545, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=26.5917602996255, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=261, Percent_Identity=26.4367816091954, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=201, Percent_Identity=26.865671641791, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=275, Percent_Identity=25.0909090909091, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=264, Percent_Identity=29.9242424242424, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=262, Percent_Identity=25.1908396946565, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=34.6456692913386, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21357041, Length=264, Percent_Identity=32.5757575757576, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=35.15625, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28571526, Length=264, Percent_Identity=31.8181818181818, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24639444, Length=258, Percent_Identity=34.1085271317829, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI21355319, Length=268, Percent_Identity=31.3432835820896, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24644337, Length=262, Percent_Identity=32.0610687022901, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737361, Length=270, Percent_Identity=30.3703703703704, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859837, Length=199, Percent_Identity=29.6482412060301, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=28.3505154639175, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.51 [H]

Molecular weight: Translated: 28527; Mature: 28527

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLEGKIALVTGAARGIGEAIARAFATAGAFVYLTDINDAQGAVVAGQIGAEAAYRRLD
CCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCHHHHHHHCC
VREEADWQCVTTEITGRHGRLDIVVNNAGITGFEDGMVAHDPEHASLDSWHAVHRTNLDG
CCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCEECCCCCCCCCCHHHHHHCCCCE
VFLGCKYAIQEMRRTGTGSIINISSRSGLVGIPAAAAYASSKAAVRNHTKTVALYCADQG
EEEHHHHHHHHHHHCCCCCEEEECCCCCEEECCHHHHHHCCHHHHHCCCEEEEEEEECCC
LAIRCNSLHPAAILTPMWEPLIGPPGAEREQRMKEFVWDTPLRRFGTPEEIAAVALLLAS
EEEEECCCCCHHHHCCCHHHCCCCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHEEC
DEVTYMTGSEITIDGGILAGSVARPSVD
CCEEEEECCEEEECCCEEECCCCCCCCC
>Mature Secondary Structure
MRRLEGKIALVTGAARGIGEAIARAFATAGAFVYLTDINDAQGAVVAGQIGAEAAYRRLD
CCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCCHHHHHHHCC
VREEADWQCVTTEITGRHGRLDIVVNNAGITGFEDGMVAHDPEHASLDSWHAVHRTNLDG
CCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCEECCCCCCCCCCHHHHHHCCCCE
VFLGCKYAIQEMRRTGTGSIINISSRSGLVGIPAAAAYASSKAAVRNHTKTVALYCADQG
EEEHHHHHHHHHHHCCCCCEEEECCCCCEEECCHHHHHHCCHHHHHCCCEEEEEEEECCC
LAIRCNSLHPAAILTPMWEPLIGPPGAEREQRMKEFVWDTPLRRFGTPEEIAAVALLLAS
EEEEECCCCCHHHHCCCHHHCCCCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHEEC
DEVTYMTGSEITIDGGILAGSVARPSVD
CCEEEEECCEEEECCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8382516; 2026158; 8617258 [H]