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The map label for this gene is tcp [H]

Identifier: 39996406

GI number: 39996406

Start: 1428274

End: 1429974

Strand: Direct

Name: tcp [H]

Synonym: GSU1304

Alternate gene names: 39996406

Gene position: 1428274-1429974 (Clockwise)

Preceding gene: 39996405

Following gene: 39996408

Centisome position: 37.45

GC content: 62.08

Gene sequence:

>1701_bases
ATGAGCTGGAAGAACCTGAAGCTGAGTCTCAAGGTGCTTGCGGGCATCGGTAGTGTCCTTGTGTTGCTGGCGGTCATCGG
CGTCTGGGCGGTGAACGGCCTGTCAAAGGTTGTCAGGGACGGCCACGAGGTAAGCGAAGGGAACAAACTGCGGGCCGAGC
TCCTCCAACGGGAGGTGGATCACCTCAACTGGGCCAAGAACGTCAGCACGTTCCTGCTGGATGGCAAGGTCAGGGAGCTC
ACCGTTCAGGTGGATCACACCAAGTGCAAGTTCGGCGAGTGGTACTACGGCGAGGGACGCAAGCAGGCCGAGGCCATGCT
TCCCGCGCTGAAGGACGAACTGGCTGCCATCGAGGAACCCCACCGCAAGCTCCACGAGTCGGCAGGGCTCATCAAGAAGG
CCTACAACAAAGAGCAGGGTGAGCAGGGCCGCAAGGACGCGGAGATCATCTTCGCGAGTCAGACCCAGCCGAACCTGCAG
CTGGTGCAGAAGCACCTGGCCGGGCTAAATGAGACATCCCGCAAGAATATCCTCTCCGATGAACAGATGATCGCCAACGC
CAACAGCACCAAGACCGCCGTGATCGCCCTGAGCATTGCCGCCCTGGTAATCGGCGTTGTTCTGGCACTGCTCATCTCCC
GTTCCATCAGCATTCCGGTCCTGAAGGGGGTTGAATTCGCCCTGAAGATAGCTGACGGCGACCTGCGGAGCACCCTCGAC
ATTGATCGGAAGGACGAGGTGGGGCAGTTGGTGGCGGCCCTCAACGACATGGTTGCCAAGCTCCGTGACATTGTAACCGA
TGTGAAGAACTCGGCCGATAACGTTGCTGCCGGCAGCCAGGAGCTCTCCTCCAGCTCCGAGGTCATGAGTCAGGGAGCCA
CCGAGCAGGCAGCCGCGGCCGAAGAGGCCTCCAGCTCCATGGAGCAGATGGCGGCCAATATCCGGCAGAACGCGGACAAC
GCCTCTCAGACTGAGAAGATCGCCCTGAAGAGCGCCACTGATGCCCGCGAGGGTGGCAAGGCTGTTGCCGGCACGGTGAG
TGCCATGAAGGAAATCGCCTCCAAGATCTCGATCATCGAGGAGATAGCCCGTCAGACGAACCTGCTGGCGTTGAACGCAG
CCATCGAAGCGGCGCGTGCCGGTGAGCACGGCAAAGGGTTCGCAGTGGTAGCGGCCGAGGTCAGAAAGCTTGCCGAACGG
AGCCAGAAGGCAGCGGGCGAGATCAGCGAACTGTCTGCCTCCAGCGTTCAGGTAGCGGAAGAGGCCGGCGAGATGCTGGC
GCGGATGGTGCCGGATATCCAGCGTACCGCGGAACTGGTGCAGGAGATCAGTGCCGCGTGCAAGGAGCAGGACTCGGGAG
CGGAGCAGATCAACAAGGCGATCCAGCAGCTTGACCAAGTGATCCAGCAGAACGCCAGCGCCAGCGAAGAGATGGCGTCC
ACCAGCGAAGAGCTGGCCGGGCAGGCGGAGCATCTCCAGTCGACCATCACATTTTTCAAAACCGACGAGCAGGGGCGGGC
TGCCGGGAGATCTCCGGCCGTGCGTCCGGCCGCGGTGGCGAAGAAGCCCGCTGCGTTGCGCCTGGGCCACGGCAACGAAC
GCCGGACGGAGCCTGTCGCGCCGCGAAAGGCTGTAGCCGGCAAGGGCGTGGACCTGAAGATGGACGGCGACTACCTGGAT
GACCAGTTCGAAAAGTTCTAG

Upstream 100 bases:

>100_bases
GTTTTACTGGGTAAACCGATACACGCAATAGTTGGAGTGAAATAAGGTTTTTCGGAGATGAGTCCGGGAAAACCCTGAGT
AACTGGAAGGAGAGGTGTCA

Downstream 100 bases:

>100_bases
CAGGCTGCTGCAAAACCGTTGTGGGGCATCTGCGTCATTGAGCAGCCATGTTTACCTTGACTAATCGCCATGGACCGTGG
GCGCCAGCCGTCTGAACGAA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 566; Mature: 565

Protein sequence:

>566_residues
MSWKNLKLSLKVLAGIGSVLVLLAVIGVWAVNGLSKVVRDGHEVSEGNKLRAELLQREVDHLNWAKNVSTFLLDGKVREL
TVQVDHTKCKFGEWYYGEGRKQAEAMLPALKDELAAIEEPHRKLHESAGLIKKAYNKEQGEQGRKDAEIIFASQTQPNLQ
LVQKHLAGLNETSRKNILSDEQMIANANSTKTAVIALSIAALVIGVVLALLISRSISIPVLKGVEFALKIADGDLRSTLD
IDRKDEVGQLVAALNDMVAKLRDIVTDVKNSADNVAAGSQELSSSSEVMSQGATEQAAAAEEASSSMEQMAANIRQNADN
ASQTEKIALKSATDAREGGKAVAGTVSAMKEIASKISIIEEIARQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAER
SQKAAGEISELSASSVQVAEEAGEMLARMVPDIQRTAELVQEISAACKEQDSGAEQINKAIQQLDQVIQQNASASEEMAS
TSEELAGQAEHLQSTITFFKTDEQGRAAGRSPAVRPAAVAKKPAALRLGHGNERRTEPVAPRKAVAGKGVDLKMDGDYLD
DQFEKF

Sequences:

>Translated_566_residues
MSWKNLKLSLKVLAGIGSVLVLLAVIGVWAVNGLSKVVRDGHEVSEGNKLRAELLQREVDHLNWAKNVSTFLLDGKVREL
TVQVDHTKCKFGEWYYGEGRKQAEAMLPALKDELAAIEEPHRKLHESAGLIKKAYNKEQGEQGRKDAEIIFASQTQPNLQ
LVQKHLAGLNETSRKNILSDEQMIANANSTKTAVIALSIAALVIGVVLALLISRSISIPVLKGVEFALKIADGDLRSTLD
IDRKDEVGQLVAALNDMVAKLRDIVTDVKNSADNVAAGSQELSSSSEVMSQGATEQAAAAEEASSSMEQMAANIRQNADN
ASQTEKIALKSATDAREGGKAVAGTVSAMKEIASKISIIEEIARQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAER
SQKAAGEISELSASSVQVAEEAGEMLARMVPDIQRTAELVQEISAACKEQDSGAEQINKAIQQLDQVIQQNASASEEMAS
TSEELAGQAEHLQSTITFFKTDEQGRAAGRSPAVRPAAVAKKPAALRLGHGNERRTEPVAPRKAVAGKGVDLKMDGDYLD
DQFEKF
>Mature_565_residues
SWKNLKLSLKVLAGIGSVLVLLAVIGVWAVNGLSKVVRDGHEVSEGNKLRAELLQREVDHLNWAKNVSTFLLDGKVRELT
VQVDHTKCKFGEWYYGEGRKQAEAMLPALKDELAAIEEPHRKLHESAGLIKKAYNKEQGEQGRKDAEIIFASQTQPNLQL
VQKHLAGLNETSRKNILSDEQMIANANSTKTAVIALSIAALVIGVVLALLISRSISIPVLKGVEFALKIADGDLRSTLDI
DRKDEVGQLVAALNDMVAKLRDIVTDVKNSADNVAAGSQELSSSSEVMSQGATEQAAAAEEASSSMEQMAANIRQNADNA
SQTEKIALKSATDAREGGKAVAGTVSAMKEIASKISIIEEIARQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAERS
QKAAGEISELSASSVQVAEEAGEMLARMVPDIQRTAELVQEISAACKEQDSGAEQINKAIQQLDQVIQQNASASEEMAST
SEELAGQAEHLQSTITFFKTDEQGRAAGRSPAVRPAAVAKKPAALRLGHGNERRTEPVAPRKAVAGKGVDLKMDGDYLDD
QFEKF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=357, Percent_Identity=37.8151260504202, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1788195, Length=276, Percent_Identity=42.7536231884058, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI1787690, Length=341, Percent_Identity=36.6568914956012, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1788194, Length=289, Percent_Identity=40.8304498269896, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1789453, Length=323, Percent_Identity=32.1981424148607, Blast_Score=162, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 60646; Mature: 60515

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWKNLKLSLKVLAGIGSVLVLLAVIGVWAVNGLSKVVRDGHEVSEGNKLRAELLQREVD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
HLNWAKNVSTFLLDGKVRELTVQVDHTKCKFGEWYYGEGRKQAEAMLPALKDELAAIEEP
HHHHHHHHHHHHCCCCEEEEEEEEECCEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
HRKLHESAGLIKKAYNKEQGEQGRKDAEIIFASQTQPNLQLVQKHLAGLNETSRKNILSD
HHHHHHHHHHHHHHHCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHCCH
EQMIANANSTKTAVIALSIAALVIGVVLALLISRSISIPVLKGVEFALKIADGDLRSTLD
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCEEEEEECCCCHHHHCC
IDRKDEVGQLVAALNDMVAKLRDIVTDVKNSADNVAAGSQELSSSSEVMSQGATEQAAAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCCHHHHHH
EEASSSMEQMAANIRQNADNASQTEKIALKSATDAREGGKAVAGTVSAMKEIASKISIIE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
EIARQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAERSQKAAGEISELSASSVQVAE
HHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
EAGEMLARMVPDIQRTAELVQEISAACKEQDSGAEQINKAIQQLDQVIQQNASASEEMAS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
TSEELAGQAEHLQSTITFFKTDEQGRAAGRSPAVRPAAVAKKPAALRLGHGNERRTEPVA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEEECCCCCCCCCCCC
PRKAVAGKGVDLKMDGDYLDDQFEKF
CHHHHCCCCCEEEECCCHHHHHHHCC
>Mature Secondary Structure 
SWKNLKLSLKVLAGIGSVLVLLAVIGVWAVNGLSKVVRDGHEVSEGNKLRAELLQREVD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
HLNWAKNVSTFLLDGKVRELTVQVDHTKCKFGEWYYGEGRKQAEAMLPALKDELAAIEEP
HHHHHHHHHHHHCCCCEEEEEEEEECCEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHH
HRKLHESAGLIKKAYNKEQGEQGRKDAEIIFASQTQPNLQLVQKHLAGLNETSRKNILSD
HHHHHHHHHHHHHHHCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHCCH
EQMIANANSTKTAVIALSIAALVIGVVLALLISRSISIPVLKGVEFALKIADGDLRSTLD
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCEEEEEECCCCHHHHCC
IDRKDEVGQLVAALNDMVAKLRDIVTDVKNSADNVAAGSQELSSSSEVMSQGATEQAAAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCCHHHHHH
EEASSSMEQMAANIRQNADNASQTEKIALKSATDAREGGKAVAGTVSAMKEIASKISIIE
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHH
EIARQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAERSQKAAGEISELSASSVQVAE
HHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
EAGEMLARMVPDIQRTAELVQEISAACKEQDSGAEQINKAIQQLDQVIQQNASASEEMAS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
TSEELAGQAEHLQSTITFFKTDEQGRAAGRSPAVRPAAVAKKPAALRLGHGNERRTEPVA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEEECCCCCCCCCCCC
PRKAVAGKGVDLKMDGDYLDDQFEKF
CHHHHCCCCCEEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]