Click here to switch to the map view.

The map label for this gene is hflX [H]

Identifier: 39996112

GI number: 39996112

Start: 1089471

End: 1091138

Strand: Direct

Name: hflX [H]

Synonym: GSU1009

Alternate gene names: 39996112

Gene position: 1089471-1091138 (Clockwise)

Preceding gene: 39996111

Following gene: 39996113

Centisome position: 28.56

GC content: 64.33

Gene sequence:

>1668_bases
ATGGGGCTCAAGCCGAGCCAGGTGGCGGCCCTTGAACGGCTCTACCGGCGCAAGGTGCCGCCCGACGAACTGATCACCCC
CGAACTGGCGGCCCGGATGGTGGATATCACCCGGGACATCCGCCGGCGGGTGGGGATTCTCGTCAACCGCCACGGCTCCG
TCGAGTATGTCATTATCGGCGACGAGCGGGGCCTCTTCATCCCCGACCTGTCCGAGTATCCGCTGGGCCGGCGGCTCCTG
AGAGGGCTTCGCTATATTCACACCAACCTGAGGGGCGGTTCCTTTACCGAGGACGACCTCACCGACCTGGCGCTCCTGCG
CTTCGATCTGATGGCGGTCATCCAGGTCCACGAGGACGACCGCCGGCTCGCCATCCAGACCGCATCGCTCAATCCCTCCG
ACGACAGTGCCCATCCCTACCGCGTGGAGTCAGCCGAGCCGCTGGCCGCCCACCGGATGGATTTCGGCGCCTTTATTTCG
AACCTCGAACGCTCTCTGGAAAAGGCCGTCGCCACCGACTCCCGGGAAGTCGCTGCCGGTACGGAACGGGCAATCCTCAT
CTCGGTCACGAAACATCCCCGGGAGGAGGCCGAGGATTCCATGGACGAGCTTCGGGAGTTGGCCCGCACCGCCGGCGTGG
CAGTTCTCGATATCGCGATCCAGCGTCCCCGCCAGTTCAATCCCCGCTACCTGATGGGGGAGGGCAAGATGCGGGAAGTC
GTGATCCGGGCGCTTCAGCTGGGAGCGACGCTTCTGATTTTCGACCAGGAGCTTTCCCCGGCCCAGGTTCGTTCCATCTC
GGCCCTGACCGAACTCAAGGTTATCGACCGGAGCCAGCTGATCCTCGACATATTTGCCCGCCGGGCCACCAGTCTTGACG
GCAAGGTCCAGGTGGAGCTTGCCCAGCTTAAGTACATCCTGCCGCGCCTCACTGGTCGCGGGGTGCAGATGTCGCGTCTG
ATGGGGGGGATCGGCGGCCGGGGGCCAGGCGAGACCAAGCTGGAGATTGACCGCCGCCGCATCAGGGACCGCATTGCCAA
GCTGGAACGGGAGCTCGAGGAGCTTTCCCGGGGCCGCCAGCAGCGGCGTCAGAAGCGGGTTCGGGCCGGCCTTCCCATCG
TCTCGATCGTGGGTTACACCAATGCGGGGAAGTCGACCCTGCTCAACGCCCTGACCAAGAGCGACGTCTTTACCGAAAAT
CTCCTCTTCGCCACCCTCGATACTTCAACCCGCCGGCTCCGCTTCCCCCGGGAGCGCGAGGTGATCATCACCGACACGGT
GGGCTTCATCCGCTCCCTGCCCGCGTCCTTGCTGGGGGCATTCAAGGCTACCCTGGAAGAACTCCAGGACGCGGATCTCC
TCCTTCACCTGGTGGACTGCGCCAATCCCCGCATCGAGGAGCAGATCGAGCAGGTGGGGAAGATCCTCGAAGAGCTTAAG
CTTGGCGATAAACCGCGCCTGGTTGTGTTCAACAAGGGGGATCTGGTGCCTGAGCTGAAGCGGAAGGCCCCTCTGGCATT
CATGAAGATCCGCCAGCTGGCTCGCCGTCACGGGGCCATCACCATCAGCGCGACAGACCGCTCGAGCCTTGAACCGCTCC
TACTGGAGATGGAGCGGCGTTTCTGGCCCGACGAGGCAGGGCAGGATGTGCCGTCCGACCTCTCCTGA

Upstream 100 bases:

>100_bases
TGCACTTCGTCGACAGCGGGTATAATATCATAGGACTTTGACAAACGAGGCTGCTGCCGGCCTCAAGGAGTTTTCAATCA
AACAGCTGCACGGCAACCTC

Downstream 100 bases:

>100_bases
GTCGAAACACCCGTCCCTTCAATTGGTTATCATCTAAAAACCTCCTAATCTTGACAGTTTGGTGAAATGCGACTATACTG
CCGCATCCGGCATGGCACCG

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MGLKPSQVAALERLYRRKVPPDELITPELAARMVDITRDIRRRVGILVNRHGSVEYVIIGDERGLFIPDLSEYPLGRRLL
RGLRYIHTNLRGGSFTEDDLTDLALLRFDLMAVIQVHEDDRRLAIQTASLNPSDDSAHPYRVESAEPLAAHRMDFGAFIS
NLERSLEKAVATDSREVAAGTERAILISVTKHPREEAEDSMDELRELARTAGVAVLDIAIQRPRQFNPRYLMGEGKMREV
VIRALQLGATLLIFDQELSPAQVRSISALTELKVIDRSQLILDIFARRATSLDGKVQVELAQLKYILPRLTGRGVQMSRL
MGGIGGRGPGETKLEIDRRRIRDRIAKLERELEELSRGRQQRRQKRVRAGLPIVSIVGYTNAGKSTLLNALTKSDVFTEN
LLFATLDTSTRRLRFPREREVIITDTVGFIRSLPASLLGAFKATLEELQDADLLLHLVDCANPRIEEQIEQVGKILEELK
LGDKPRLVVFNKGDLVPELKRKAPLAFMKIRQLARRHGAITISATDRSSLEPLLLEMERRFWPDEAGQDVPSDLS

Sequences:

>Translated_555_residues
MGLKPSQVAALERLYRRKVPPDELITPELAARMVDITRDIRRRVGILVNRHGSVEYVIIGDERGLFIPDLSEYPLGRRLL
RGLRYIHTNLRGGSFTEDDLTDLALLRFDLMAVIQVHEDDRRLAIQTASLNPSDDSAHPYRVESAEPLAAHRMDFGAFIS
NLERSLEKAVATDSREVAAGTERAILISVTKHPREEAEDSMDELRELARTAGVAVLDIAIQRPRQFNPRYLMGEGKMREV
VIRALQLGATLLIFDQELSPAQVRSISALTELKVIDRSQLILDIFARRATSLDGKVQVELAQLKYILPRLTGRGVQMSRL
MGGIGGRGPGETKLEIDRRRIRDRIAKLERELEELSRGRQQRRQKRVRAGLPIVSIVGYTNAGKSTLLNALTKSDVFTEN
LLFATLDTSTRRLRFPREREVIITDTVGFIRSLPASLLGAFKATLEELQDADLLLHLVDCANPRIEEQIEQVGKILEELK
LGDKPRLVVFNKGDLVPELKRKAPLAFMKIRQLARRHGAITISATDRSSLEPLLLEMERRFWPDEAGQDVPSDLS
>Mature_554_residues
GLKPSQVAALERLYRRKVPPDELITPELAARMVDITRDIRRRVGILVNRHGSVEYVIIGDERGLFIPDLSEYPLGRRLLR
GLRYIHTNLRGGSFTEDDLTDLALLRFDLMAVIQVHEDDRRLAIQTASLNPSDDSAHPYRVESAEPLAAHRMDFGAFISN
LERSLEKAVATDSREVAAGTERAILISVTKHPREEAEDSMDELRELARTAGVAVLDIAIQRPRQFNPRYLMGEGKMREVV
IRALQLGATLLIFDQELSPAQVRSISALTELKVIDRSQLILDIFARRATSLDGKVQVELAQLKYILPRLTGRGVQMSRLM
GGIGGRGPGETKLEIDRRRIRDRIAKLERELEELSRGRQQRRQKRVRAGLPIVSIVGYTNAGKSTLLNALTKSDVFTENL
LFATLDTSTRRLRFPREREVIITDTVGFIRSLPASLLGAFKATLEELQDADLLLHLVDCANPRIEEQIEQVGKILEELKL
GDKPRLVVFNKGDLVPELKRKAPLAFMKIRQLARRHGAITISATDRSSLEPLLLEMERRFWPDEAGQDVPSDLS

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=196, Percent_Identity=36.734693877551, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI310133118, Length=206, Percent_Identity=35.9223300970874, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI310124269, Length=182, Percent_Identity=37.9120879120879, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI310124267, Length=182, Percent_Identity=37.9120879120879, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI310124171, Length=182, Percent_Identity=37.9120879120879, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI310124169, Length=182, Percent_Identity=37.9120879120879, Blast_Score=116, Evalue=6e-26,
Organism=Escherichia coli, GI1790615, Length=319, Percent_Identity=45.4545454545455, Blast_Score=279, Evalue=4e-76,
Organism=Caenorhabditis elegans, GI17561038, Length=235, Percent_Identity=30.6382978723404, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24650079, Length=331, Percent_Identity=35.3474320241692, Blast_Score=132, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 62560; Mature: 62429

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLKPSQVAALERLYRRKVPPDELITPELAARMVDITRDIRRRVGILVNRHGSVEYVIIG
CCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCCEEEEEEE
DERGLFIPDLSEYPLGRRLLRGLRYIHTNLRGGSFTEDDLTDLALLRFDLMAVIQVHEDD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
RRLAIQTASLNPSDDSAHPYRVESAEPLAAHRMDFGAFISNLERSLEKAVATDSREVAAG
CEEEEEEECCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCC
TERAILISVTKHPREEAEDSMDELRELARTAGVAVLDIAIQRPRQFNPRYLMGEGKMREV
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCHHEEHHHHHCCCCCCCCEEECCCHHHHH
VIRALQLGATLLIFDQELSPAQVRSISALTELKVIDRSQLILDIFARRATSLDGKVQVEL
HHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
AQLKYILPRLTGRGVQMSRLMGGIGGRGPGETKLEIDRRRIRDRIAKLERELEELSRGRQ
HHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRQKRVRAGLPIVSIVGYTNAGKSTLLNALTKSDVFTENLLFATLDTSTRRLRFPRERE
HHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCEEEEEECCCHHHHCCCCCCC
VIITDTVGFIRSLPASLLGAFKATLEELQDADLLLHLVDCANPRIEEQIEQVGKILEELK
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LGDKPRLVVFNKGDLVPELKRKAPLAFMKIRQLARRHGAITISATDRSSLEPLLLEMERR
CCCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHH
FWPDEAGQDVPSDLS
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
GLKPSQVAALERLYRRKVPPDELITPELAARMVDITRDIRRRVGILVNRHGSVEYVIIG
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEECCCCEEEEEEE
DERGLFIPDLSEYPLGRRLLRGLRYIHTNLRGGSFTEDDLTDLALLRFDLMAVIQVHEDD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
RRLAIQTASLNPSDDSAHPYRVESAEPLAAHRMDFGAFISNLERSLEKAVATDSREVAAG
CEEEEEEECCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCC
TERAILISVTKHPREEAEDSMDELRELARTAGVAVLDIAIQRPRQFNPRYLMGEGKMREV
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCHHEEHHHHHCCCCCCCCEEECCCHHHHH
VIRALQLGATLLIFDQELSPAQVRSISALTELKVIDRSQLILDIFARRATSLDGKVQVEL
HHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
AQLKYILPRLTGRGVQMSRLMGGIGGRGPGETKLEIDRRRIRDRIAKLERELEELSRGRQ
HHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRQKRVRAGLPIVSIVGYTNAGKSTLLNALTKSDVFTENLLFATLDTSTRRLRFPRERE
HHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCEEEEEECCCHHHHCCCCCCC
VIITDTVGFIRSLPASLLGAFKATLEELQDADLLLHLVDCANPRIEEQIEQVGKILEELK
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LGDKPRLVVFNKGDLVPELKRKAPLAFMKIRQLARRHGAITISATDRSSLEPLLLEMERR
CCCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHH
FWPDEAGQDVPSDLS
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]