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The map label for this gene is ntrC [H]

Identifier: 39996106

GI number: 39996106

Start: 1082803

End: 1084248

Strand: Reverse

Name: ntrC [H]

Synonym: GSU1003

Alternate gene names: 39996106

Gene position: 1084248-1082803 (Counterclockwise)

Preceding gene: 39996107

Following gene: 39996105

Centisome position: 28.43

GC content: 58.92

Gene sequence:

>1446_bases
ATGTTACTGAACCGCATATTGGTTGCCGATGACGAAGAAAGCATGCGCTGGGTCCTCTCGAAGGCCCTGCGCAAAAAGGG
ATTCACCGTGGACCTCGCCCGCGACGGAGAGGAAGCCCTGCGACTGATCCAGTCCAACGAGTACGACTTGGCCATCCTCG
ACATCAAGATGCCCGGCTTCACCGGGCTGGAATTGCTCGACAAGGTACGGGAGCTCAAGCACGATCTCCTCATGGTGATC
ATGACCGCCGAGGCGAGCATGAAAAACGCCGTGGAGGCCATGAAGCGGGGGGCCTACGATTACATCACCAAGCCCTTCGA
CCTGGATGTAATCGATGCCATCATCGAAAAGGTGCACAAGGCCCGGGAGATCACCTCCCAAATGACTATTCTGCGGGAAG
AGCTGAAAGAGCGCTATCACCTGGAGAAGAACATCATCGGCAACTCCCCCGCCATGCGGGAAGTCTACAAGACCATCGGC
AAGGTTGCCCCCAGCGACGTGACCGTTCTCGTTCAGGGGGAGTCAGGGACCGGCAAAGAGCTCATCGCCCGGGCTATTCA
CTTCAACTCCAAGCGGATCGGCAAGCCGTTCATCGCCCTCAACTGCGCCGCCATTCCCAAAGATTTGCTGGAAAGCGAAC
TCTTCGGCTTCGAAAAGGGGGCGTTCACCGGCGCCGTCGAGCGCAAGCTGGGCAAGTTTGAGCAGGCCAACGGCGGCACC
ATCTTCCTTGACGAGATCGGCGACATGCCCCTCGATCTCCAGGCAAAAATCCTGCGGGTGCTCCAGGAGAAGGAAGTTAC
CCGCACCGGCGGCAGCCAGAACATCGCCGTGGACGTACGGATCGTGGCAGCCACCAACCAGAACCTGGAGGAACTGGTCC
GCAAGAAGCAGTTCCGGGAGGATCTCTTCTACCGGCTCAACGTGGTGCCTATTCAGCTGGTACCGCTGAGGGAGCGTAAG
GAAGACGTGCCGCTTCTGGTGGACTATTTCCTCCAAAACGCCTGCGCGGAACTGGAGGTTTCGCCAAAAAAATGCTCTCC
CGAGGCCATGGCGCTCCTCACCACCCACAGCTGGCCGGGCAACGTACGGGAACTGGAGAATACCATCAAGCGGGCGGTGA
TCCTCTCGTCCGACCCGCTTCTCACCCCATCCGACTTTCCGGGGCTGCGTGCCCGCCAGACGGGAAGCGAGGCGACCGCT
GCGGACGACCTCTCCCTGGAAGCCCTGGTGGACATGAAACTGCGGGCAAGCCTCACCAACCTGGACAAAATGGAGAGCGG
GGATATCTATAACCTGGTCCTCAAGCAGATCGAGCGGCCTCTCATCCGCTTCGTCCTGGAAAAGACGCGTGGCAACCAGG
TGAAAGGAGCTGAGATCCTCGGCATTAACCGCAACACGCTACGCAAGAAGATTCAGGAGCTGGGCATCGAACTGAGAAAA
GACTGA

Upstream 100 bases:

>100_bases
GGCAAAGGGACCACCTTCACGGTGATGCTCCCCCTGATTCAGTAGCCGGGATCTTTCCCTTAACCATGTTCACTTCCATA
TCCACAGTTCGAGGTCTGCA

Downstream 100 bases:

>100_bases
AAGGAGGGAGCATCTGATGGGAATTATGGAGAAGTTCTTCCTCGACCGGCAGCAGGCAGTGCTCGTGGTCATCGACGTGC
AGGAAAAGCTCTGCGCGGCC

Product: nitrogen regulation protein NR(I)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MLLNRILVADDEESMRWVLSKALRKKGFTVDLARDGEEALRLIQSNEYDLAILDIKMPGFTGLELLDKVRELKHDLLMVI
MTAEASMKNAVEAMKRGAYDYITKPFDLDVIDAIIEKVHKAREITSQMTILREELKERYHLEKNIIGNSPAMREVYKTIG
KVAPSDVTVLVQGESGTGKELIARAIHFNSKRIGKPFIALNCAAIPKDLLESELFGFEKGAFTGAVERKLGKFEQANGGT
IFLDEIGDMPLDLQAKILRVLQEKEVTRTGGSQNIAVDVRIVAATNQNLEELVRKKQFREDLFYRLNVVPIQLVPLRERK
EDVPLLVDYFLQNACAELEVSPKKCSPEAMALLTTHSWPGNVRELENTIKRAVILSSDPLLTPSDFPGLRARQTGSEATA
ADDLSLEALVDMKLRASLTNLDKMESGDIYNLVLKQIERPLIRFVLEKTRGNQVKGAEILGINRNTLRKKIQELGIELRK
D

Sequences:

>Translated_481_residues
MLLNRILVADDEESMRWVLSKALRKKGFTVDLARDGEEALRLIQSNEYDLAILDIKMPGFTGLELLDKVRELKHDLLMVI
MTAEASMKNAVEAMKRGAYDYITKPFDLDVIDAIIEKVHKAREITSQMTILREELKERYHLEKNIIGNSPAMREVYKTIG
KVAPSDVTVLVQGESGTGKELIARAIHFNSKRIGKPFIALNCAAIPKDLLESELFGFEKGAFTGAVERKLGKFEQANGGT
IFLDEIGDMPLDLQAKILRVLQEKEVTRTGGSQNIAVDVRIVAATNQNLEELVRKKQFREDLFYRLNVVPIQLVPLRERK
EDVPLLVDYFLQNACAELEVSPKKCSPEAMALLTTHSWPGNVRELENTIKRAVILSSDPLLTPSDFPGLRARQTGSEATA
ADDLSLEALVDMKLRASLTNLDKMESGDIYNLVLKQIERPLIRFVLEKTRGNQVKGAEILGINRNTLRKKIQELGIELRK
D
>Mature_481_residues
MLLNRILVADDEESMRWVLSKALRKKGFTVDLARDGEEALRLIQSNEYDLAILDIKMPGFTGLELLDKVRELKHDLLMVI
MTAEASMKNAVEAMKRGAYDYITKPFDLDVIDAIIEKVHKAREITSQMTILREELKERYHLEKNIIGNSPAMREVYKTIG
KVAPSDVTVLVQGESGTGKELIARAIHFNSKRIGKPFIALNCAAIPKDLLESELFGFEKGAFTGAVERKLGKFEQANGGT
IFLDEIGDMPLDLQAKILRVLQEKEVTRTGGSQNIAVDVRIVAATNQNLEELVRKKQFREDLFYRLNVVPIQLVPLRERK
EDVPLLVDYFLQNACAELEVSPKKCSPEAMALLTTHSWPGNVRELENTIKRAVILSSDPLLTPSDFPGLRARQTGSEATA
ADDLSLEALVDMKLRASLTNLDKMESGDIYNLVLKQIERPLIRFVLEKTRGNQVKGAEILGINRNTLRKKIQELGIELRK
D

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=479, Percent_Identity=44.0501043841336, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1790299, Length=482, Percent_Identity=44.6058091286307, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI1790437, Length=466, Percent_Identity=41.8454935622318, Blast_Score=354, Evalue=8e-99,
Organism=Escherichia coli, GI1788905, Length=465, Percent_Identity=38.0645161290323, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI87082117, Length=363, Percent_Identity=45.1790633608815, Blast_Score=285, Evalue=6e-78,
Organism=Escherichia coli, GI1789233, Length=336, Percent_Identity=44.3452380952381, Blast_Score=261, Evalue=9e-71,
Organism=Escherichia coli, GI1789087, Length=368, Percent_Identity=42.1195652173913, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI87082152, Length=235, Percent_Identity=51.9148936170213, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1786524, Length=332, Percent_Identity=43.3734939759036, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI87081872, Length=332, Percent_Identity=39.1566265060241, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1787583, Length=241, Percent_Identity=45.2282157676349, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI87081858, Length=394, Percent_Identity=28.6802030456853, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1789828, Length=252, Percent_Identity=34.1269841269841, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1788713, Length=186, Percent_Identity=31.1827956989247, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786784, Length=102, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082012, Length=103, Percent_Identity=33.0097087378641, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788191, Length=119, Percent_Identity=34.453781512605, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787375, Length=105, Percent_Identity=34.2857142857143, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789809, Length=103, Percent_Identity=31.0679611650485, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789402, Length=116, Percent_Identity=32.7586206896552, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI145693157, Length=122, Percent_Identity=31.1475409836066, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789661, Length=86, Percent_Identity=37.2093023255814, Blast_Score=63, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=172, Percent_Identity=26.1627906976744, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 54105; Mature: 54105

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLNRILVADDEESMRWVLSKALRKKGFTVDLARDGEEALRLIQSNEYDLAILDIKMPGF
CCCCCEEEECCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCEEEEEEECCCC
TGLELLDKVRELKHDLLMVIMTAEASMKNAVEAMKRGAYDYITKPFDLDVIDAIIEKVHK
CHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHH
AREITSQMTILREELKERYHLEKNIIGNSPAMREVYKTIGKVAPSDVTVLVQGESGTGKE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHH
LIARAIHFNSKRIGKPFIALNCAAIPKDLLESELFGFEKGAFTGAVERKLGKFEQANGGT
HHHHHHHCCCCCCCCCEEEEECHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCHHCCCCCE
IFLDEIGDMPLDLQAKILRVLQEKEVTRTGGSQNIAVDVRIVAATNQNLEELVRKKQFRE
EEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHH
DLFYRLNVVPIQLVPLRERKEDVPLLVDYFLQNACAELEVSPKKCSPEAMALLTTHSWPG
HHHHEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCC
NVRELENTIKRAVILSSDPLLTPSDFPGLRARQTGSEATAADDLSLEALVDMKLRASLTN
CHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LDKMESGDIYNLVLKQIERPLIRFVLEKTRGNQVKGAEILGINRNTLRKKIQELGIELRK
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHCCCCCC
D
C
>Mature Secondary Structure
MLLNRILVADDEESMRWVLSKALRKKGFTVDLARDGEEALRLIQSNEYDLAILDIKMPGF
CCCCCEEEECCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCEEEEEEECCCC
TGLELLDKVRELKHDLLMVIMTAEASMKNAVEAMKRGAYDYITKPFDLDVIDAIIEKVHK
CHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHH
AREITSQMTILREELKERYHLEKNIIGNSPAMREVYKTIGKVAPSDVTVLVQGESGTGKE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHH
LIARAIHFNSKRIGKPFIALNCAAIPKDLLESELFGFEKGAFTGAVERKLGKFEQANGGT
HHHHHHHCCCCCCCCCEEEEECHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCHHCCCCCE
IFLDEIGDMPLDLQAKILRVLQEKEVTRTGGSQNIAVDVRIVAATNQNLEELVRKKQFRE
EEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHH
DLFYRLNVVPIQLVPLRERKEDVPLLVDYFLQNACAELEVSPKKCSPEAMALLTTHSWPG
HHHHEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCC
NVRELENTIKRAVILSSDPLLTPSDFPGLRARQTGSEATAADDLSLEALVDMKLRASLTN
CHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LDKMESGDIYNLVLKQIERPLIRFVLEKTRGNQVKGAEILGINRNTLRKKIQELGIELRK
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHCCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7553451 [H]