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The map label for this gene is pkn1 [H]

Identifier: 39996002

GI number: 39996002

Start: 962153

End: 963028

Strand: Direct

Name: pkn1 [H]

Synonym: GSU0897

Alternate gene names: 39996002

Gene position: 962153-963028 (Clockwise)

Preceding gene: 39995999

Following gene: 39996003

Centisome position: 25.23

GC content: 64.61

Gene sequence:

>876_bases
ATGATCCGTGCCGTGCATAGTGCGGCGATTGTGTTGCTTGTTTTCAGTTATATGGCGGAATTTTCCGGTGCCGCTTCTGG
GGGGTACGCCCCAGCTTCGGTCGGGACTCAGCCTGTAGGGACAAGCTTTCGCGACCGGCTGGCCGACGGATCGCCCGGTC
CGGTCATGGTGGTGATTCCACCGGGTCGCTTCCGCATGGGAGCAATTTTCGGCGGTGGCGACCCTGACGAGAAGCCGGTC
CATGAGGTGAGCATTCCCCGAGCCTTTGCCATCGGGGCGTATGAGGTGACCTTTGCCGAGTACGATCGGTTCTGCGAAGC
CACGGGTCGTGAAAAACCCAAGGATGGCCGCCGCTGGTTCGGCCCCTTGTCGCGAAACTGGGGAAGGGGCAACAAGCCGG
CCATGAATGTCTCCTGGGATGATGCGGTGGCCTACGTCAAATGGTTGTCTGACCAGACGGGACACCGCTATCGCCTGCCG
AGTGAGGCCGAGTGGGAGTACGCGGCCCGCGGCGGCAAGGATACCCCCTACTGGTGGGGTGGCACGGTCGGCCAGAACAA
GGCCAACTGCAAGGGGTGCGGCAGCCGGTGGGACAAGAAGATTACTGCACCGGTGGGCTCCTTCGCGCCCAACCCCTACG
GTATGTTCGACACCGCCGGCAACGTGTGGGAGTGGTGCGTCGACACCTGGCACGAGAGTTACGACGGCGCCCCGGCGGAT
GGCTCTCCCTGGATCGGCGGAGAGGATTCCCGCCGGGTCCAGCGGGGAGGGTCCTTCGGCAGCAAGCCCCGCTACATCCG
CTCATCGGCCCGGGGGCGGGGTGCCCAGGATGGCCGCTACGTCTACCTGGGCTTCCGGGTCGTGCGGGAACTCTGA

Upstream 100 bases:

>100_bases
TCGGTGCAAAACAGCTTGGTGGCCGGGTTGTCTTTTGCGGGGGCTGTGCGTACAATAGTGAGTCCGTGGCCACAGTTTTT
TCGGAGGGAGATGCATGAAG

Downstream 100 bases:

>100_bases
CCGTGGGGCACGAAACCCTCGCCGTCCTCCGCACGGTCTTCGGGTACCGGTCCTTCCGCCCGTTCCAGGAGGAGATCGTT
GACCGGGTGGCGCGCGGGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MIRAVHSAAIVLLVFSYMAEFSGAASGGYAPASVGTQPVGTSFRDRLADGSPGPVMVVIPPGRFRMGAIFGGGDPDEKPV
HEVSIPRAFAIGAYEVTFAEYDRFCEATGREKPKDGRRWFGPLSRNWGRGNKPAMNVSWDDAVAYVKWLSDQTGHRYRLP
SEAEWEYAARGGKDTPYWWGGTVGQNKANCKGCGSRWDKKITAPVGSFAPNPYGMFDTAGNVWEWCVDTWHESYDGAPAD
GSPWIGGEDSRRVQRGGSFGSKPRYIRSSARGRGAQDGRYVYLGFRVVREL

Sequences:

>Translated_291_residues
MIRAVHSAAIVLLVFSYMAEFSGAASGGYAPASVGTQPVGTSFRDRLADGSPGPVMVVIPPGRFRMGAIFGGGDPDEKPV
HEVSIPRAFAIGAYEVTFAEYDRFCEATGREKPKDGRRWFGPLSRNWGRGNKPAMNVSWDDAVAYVKWLSDQTGHRYRLP
SEAEWEYAARGGKDTPYWWGGTVGQNKANCKGCGSRWDKKITAPVGSFAPNPYGMFDTAGNVWEWCVDTWHESYDGAPAD
GSPWIGGEDSRRVQRGGSFGSKPRYIRSSARGRGAQDGRYVYLGFRVVREL
>Mature_291_residues
MIRAVHSAAIVLLVFSYMAEFSGAASGGYAPASVGTQPVGTSFRDRLADGSPGPVMVVIPPGRFRMGAIFGGGDPDEKPV
HEVSIPRAFAIGAYEVTFAEYDRFCEATGREKPKDGRRWFGPLSRNWGRGNKPAMNVSWDDAVAYVKWLSDQTGHRYRLP
SEAEWEYAARGGKDTPYWWGGTVGQNKANCKGCGSRWDKKITAPVGSFAPNPYGMFDTAGNVWEWCVDTWHESYDGAPAD
GSPWIGGEDSRRVQRGGSFGSKPRYIRSSARGRGAQDGRYVYLGFRVVREL

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=289, Percent_Identity=34.2560553633218, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI38202250, Length=314, Percent_Identity=32.1656050955414, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI257470977, Length=311, Percent_Identity=29.903536977492, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI194248087, Length=268, Percent_Identity=31.3432835820896, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI194248088, Length=283, Percent_Identity=28.9752650176678, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI226437577, Length=173, Percent_Identity=35.8381502890173, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20130397, Length=355, Percent_Identity=25.3521126760563, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 31940; Mature: 31940

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRAVHSAAIVLLVFSYMAEFSGAASGGYAPASVGTQPVGTSFRDRLADGSPGPVMVVIP
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEC
PGRFRMGAIFGGGDPDEKPVHEVSIPRAFAIGAYEVTFAEYDRFCEATGREKPKDGRRWF
CCCEEEEEEECCCCCCCCCCHHHCCCCEEECCEEEEHHHHHHHHHHHCCCCCCCCCHHHC
GPLSRNWGRGNKPAMNVSWDDAVAYVKWLSDQTGHRYRLPSEAEWEYAARGGKDTPYWWG
CCHHCCCCCCCCCEECCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHCCCCCCCCCCC
GTVGQNKANCKGCGSRWDKKITAPVGSFAPNPYGMFDTAGNVWEWCVDTWHESYDGAPAD
CCCCCCCCCCCCCHHHHCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
GSPWIGGEDSRRVQRGGSFGSKPRYIRSSARGRGAQDGRYVYLGFRVVREL
CCCCCCCCCHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCEEEEHHHHHHCC
>Mature Secondary Structure
MIRAVHSAAIVLLVFSYMAEFSGAASGGYAPASVGTQPVGTSFRDRLADGSPGPVMVVIP
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEC
PGRFRMGAIFGGGDPDEKPVHEVSIPRAFAIGAYEVTFAEYDRFCEATGREKPKDGRRWF
CCCEEEEEEECCCCCCCCCCHHHCCCCEEECCEEEEHHHHHHHHHHHCCCCCCCCCHHHC
GPLSRNWGRGNKPAMNVSWDDAVAYVKWLSDQTGHRYRLPSEAEWEYAARGGKDTPYWWG
CCHHCCCCCCCCCEECCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHCCCCCCCCCCC
GTVGQNKANCKGCGSRWDKKITAPVGSFAPNPYGMFDTAGNVWEWCVDTWHESYDGAPAD
CCCCCCCCCCCCCHHHHCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
GSPWIGGEDSRRVQRGGSFGSKPRYIRSSARGRGAQDGRYVYLGFRVVREL
CCCCCCCCCHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCEEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]