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The map label for this gene is recQ [H]

Identifier: 39996003

GI number: 39996003

Start: 963031

End: 964842

Strand: Direct

Name: recQ [H]

Synonym: GSU0898

Alternate gene names: 39996003

Gene position: 963031-964842 (Clockwise)

Preceding gene: 39996002

Following gene: 39996004

Centisome position: 25.25

GC content: 68.49

Gene sequence:

>1812_bases
GTGGGGCACGAAACCCTCGCCGTCCTCCGCACGGTCTTCGGGTACCGGTCCTTCCGCCCGTTCCAGGAGGAGATCGTTGA
CCGGGTGGCGCGCGGGGGCGATACGTTCGTCCTGATGCCCACCGGCGGCGGCAAGTCCCTCTGTTACCAGATACCCTCCC
TGGTACGGCCCGGCGTGGGGATCGTGATTTCCCCCCTCATTTCCCTCATGAAGGACCAGGTGGATGCCCTGCGCGAGAAC
GGCGTGGCAGCGGCCTGCTACAACTCGACCCTGGGCGAGCGGGAGTCGCGCCGGGTGCTCGCCCGGCTCCACGGCGGCGA
GCTGGACCTTCTCTACGTGGCCCCGGAACGGCTCATGACCGATGCCTTTCTGGAGCGGCTACGGGAGATACCCATCGCGC
TCTTCGCCATTGATGAGGCCCACTGCGTCTCCCAGTGGGGGCACGATTTCCGTCCTGAGTACGTGGAGCTGGGACGGTTG
CGGGGGCTGTTCCCGACCGTGCCGATGATCGCCCTGACCGCCACCGCCGACGCCCAGACCCGAGGCGACATCGTGACGCG
GCTGGGGCTTCGGGACGCCGAGATGTTCGTGACCGGCTTCGACCGGCCCAATATCCGCTACAGCGTTCTGGAAAAGCAGA
AGCCGTTCCGACAACTGGAGGAGTTCCTGGCGACGCGCCCCCGGGAGGCGGGCATTGTCTACTGCCTTTCCCGCAAGCGG
GTGGAAGAAGTGGCGGAGAAGCTCCGGGCGGCCGGGGTGGAGGCGGGGGCCTATCACGCCGGGCTTGCCGACGCGGAACG
GAGCCGGGTCCAGGAGGCGTTCCTGCGGGACGACATCCGGGTGGTGGTGGCCACGGTGGCCTTCGGCATGGGGATCGACA
AGCCCAACGTCCGGTTTGTAGTCCACTACGACCTGCCCAAGAACATCGAGAGTTACTACCAGGAAACCGGGCGGGCCGGC
CGCGACGGTCTCCCGGCCGAGGCGCTGCTCCTCTTCGGCTACGGCGACATCCCGGTCTCCCGCTCCCTCATCGAGTCGGG
CGGGAACCCCGAGCAGGTGCGGATCGAGCTGCACAAGCTGAACGCGATGGTGGGGTTCGCCGAGGCACTCGTCTGCCGGC
GCCGGGCACTGCTCGGCTACTTCGGCGAGCGGCTGGAGGAACCTTGTGGCAACTGCGACCTCTGTCTGGCTCCGCCCGAA
ACCTTCGATGCCACCGAAGAGGCCCGCAAGGCCCTTTCCTGCGTCTACCGGGTGGGGCAGCGCTTCGGCGTGGGGCACGT
GATCGATGTCCTGCGCGGTTCGCGGAGTGAACGCATCCTGGCCCTGGGCCACGACCGGCTCTCGACCTACGGCATCGGCG
CCAGCCTGGCGGCCGAGGCCTGGGGGAGCATCATCCGCCAGCTCATCCACCGGGGATACCTGGAGCAGGACCTGGCCAAC
TACTCGGTGCTGAAGCTGACCCCTGCGGCCCGGCCGCTGCTGCGGGGCGAGGAGAGCCTGGTCCTGGCGAAGCCGCGGCT
GCGGATGGCCGCTCCGAAAAAGGAAAAGGCCCCCCGCCGGCCGGGAGCCGCCACGCCGGCGGAGCGGGACGAGGAGCTCT
TCCAGGAGCTGCGGGCGCTCCGCAAACGGTTGGCGGATGACCAGCAGGTTCCTCCGTATATCATCTTCAGCGATGCGACC
CTGGCCGAGATGGCGTCGCTGCGGCCGACCACGCCGGAAGAACTTTTGCGGGTGAACGGGGTGGGCGAGCGGAAGCTCGG
CCGCTACGGCGCCCCGTTCCTGGAGGCGATCCGGAGCCATGGCGCCGGTTGA

Upstream 100 bases:

>100_bases
GCAGCAAGCCCCGCTACATCCGCTCATCGGCCCGGGGGCGGGGTGCCCAGGATGGCCGCTACGTCTACCTGGGCTTCCGG
GTCGTGCGGGAACTCTGACC

Downstream 100 bases:

>100_bases
GTGGGTTCTTTCCCCGTTCCCCATGTTGCGCGGGGCGCTCCGGTGTGCTATTGAACCGGGTGGGCCGACGCCCGAAGCGC
TCGCCGTTTCCCATCCCCTT

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MGHETLAVLRTVFGYRSFRPFQEEIVDRVARGGDTFVLMPTGGGKSLCYQIPSLVRPGVGIVISPLISLMKDQVDALREN
GVAAACYNSTLGERESRRVLARLHGGELDLLYVAPERLMTDAFLERLREIPIALFAIDEAHCVSQWGHDFRPEYVELGRL
RGLFPTVPMIALTATADAQTRGDIVTRLGLRDAEMFVTGFDRPNIRYSVLEKQKPFRQLEEFLATRPREAGIVYCLSRKR
VEEVAEKLRAAGVEAGAYHAGLADAERSRVQEAFLRDDIRVVVATVAFGMGIDKPNVRFVVHYDLPKNIESYYQETGRAG
RDGLPAEALLLFGYGDIPVSRSLIESGGNPEQVRIELHKLNAMVGFAEALVCRRRALLGYFGERLEEPCGNCDLCLAPPE
TFDATEEARKALSCVYRVGQRFGVGHVIDVLRGSRSERILALGHDRLSTYGIGASLAAEAWGSIIRQLIHRGYLEQDLAN
YSVLKLTPAARPLLRGEESLVLAKPRLRMAAPKKEKAPRRPGAATPAERDEELFQELRALRKRLADDQQVPPYIIFSDAT
LAEMASLRPTTPEELLRVNGVGERKLGRYGAPFLEAIRSHGAG

Sequences:

>Translated_603_residues
MGHETLAVLRTVFGYRSFRPFQEEIVDRVARGGDTFVLMPTGGGKSLCYQIPSLVRPGVGIVISPLISLMKDQVDALREN
GVAAACYNSTLGERESRRVLARLHGGELDLLYVAPERLMTDAFLERLREIPIALFAIDEAHCVSQWGHDFRPEYVELGRL
RGLFPTVPMIALTATADAQTRGDIVTRLGLRDAEMFVTGFDRPNIRYSVLEKQKPFRQLEEFLATRPREAGIVYCLSRKR
VEEVAEKLRAAGVEAGAYHAGLADAERSRVQEAFLRDDIRVVVATVAFGMGIDKPNVRFVVHYDLPKNIESYYQETGRAG
RDGLPAEALLLFGYGDIPVSRSLIESGGNPEQVRIELHKLNAMVGFAEALVCRRRALLGYFGERLEEPCGNCDLCLAPPE
TFDATEEARKALSCVYRVGQRFGVGHVIDVLRGSRSERILALGHDRLSTYGIGASLAAEAWGSIIRQLIHRGYLEQDLAN
YSVLKLTPAARPLLRGEESLVLAKPRLRMAAPKKEKAPRRPGAATPAERDEELFQELRALRKRLADDQQVPPYIIFSDAT
LAEMASLRPTTPEELLRVNGVGERKLGRYGAPFLEAIRSHGAG
>Mature_602_residues
GHETLAVLRTVFGYRSFRPFQEEIVDRVARGGDTFVLMPTGGGKSLCYQIPSLVRPGVGIVISPLISLMKDQVDALRENG
VAAACYNSTLGERESRRVLARLHGGELDLLYVAPERLMTDAFLERLREIPIALFAIDEAHCVSQWGHDFRPEYVELGRLR
GLFPTVPMIALTATADAQTRGDIVTRLGLRDAEMFVTGFDRPNIRYSVLEKQKPFRQLEEFLATRPREAGIVYCLSRKRV
EEVAEKLRAAGVEAGAYHAGLADAERSRVQEAFLRDDIRVVVATVAFGMGIDKPNVRFVVHYDLPKNIESYYQETGRAGR
DGLPAEALLLFGYGDIPVSRSLIESGGNPEQVRIELHKLNAMVGFAEALVCRRRALLGYFGERLEEPCGNCDLCLAPPET
FDATEEARKALSCVYRVGQRFGVGHVIDVLRGSRSERILALGHDRLSTYGIGASLAAEAWGSIIRQLIHRGYLEQDLANY
SVLKLTPAARPLLRGEESLVLAKPRLRMAAPKKEKAPRRPGAATPAERDEELFQELRALRKRLADDQQVPPYIIFSDATL
AEMASLRPTTPEELLRVNGVGERKLGRYGAPFLEAIRSHGAG

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=645, Percent_Identity=36.2790697674419, Blast_Score=371, Evalue=1e-102,
Organism=Homo sapiens, GI110735439, Length=501, Percent_Identity=38.7225548902196, Blast_Score=338, Evalue=7e-93,
Organism=Homo sapiens, GI169218196, Length=501, Percent_Identity=38.7225548902196, Blast_Score=338, Evalue=1e-92,
Organism=Homo sapiens, GI14591902, Length=519, Percent_Identity=37.3795761078998, Blast_Score=317, Evalue=3e-86,
Organism=Homo sapiens, GI14591904, Length=519, Percent_Identity=37.3795761078998, Blast_Score=317, Evalue=3e-86,
Organism=Homo sapiens, GI148612816, Length=420, Percent_Identity=40.9523809523809, Blast_Score=299, Evalue=5e-81,
Organism=Homo sapiens, GI51242947, Length=392, Percent_Identity=41.0714285714286, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI51242943, Length=392, Percent_Identity=41.0714285714286, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI284005309, Length=353, Percent_Identity=38.5269121813031, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI7661920, Length=355, Percent_Identity=22.5352112676056, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI222352149, Length=357, Percent_Identity=22.4089635854342, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI55749865, Length=348, Percent_Identity=20.9770114942529, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI21071032, Length=92, Percent_Identity=36.9565217391304, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI48994977, Length=596, Percent_Identity=55.8724832214765, Blast_Score=684, Evalue=0.0,
Organism=Escherichia coli, GI1787016, Length=344, Percent_Identity=24.1279069767442, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI87082221, Length=339, Percent_Identity=23.8938053097345, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790214, Length=120, Percent_Identity=29.1666666666667, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25145561, Length=659, Percent_Identity=35.660091047041, Blast_Score=383, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI32564293, Length=671, Percent_Identity=33.9791356184799, Blast_Score=336, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI71987997, Length=552, Percent_Identity=35.6884057971014, Blast_Score=317, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI71987993, Length=552, Percent_Identity=35.6884057971014, Blast_Score=317, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI17552866, Length=444, Percent_Identity=36.9369369369369, Blast_Score=281, Evalue=5e-76,
Organism=Caenorhabditis elegans, GI17507121, Length=357, Percent_Identity=24.6498599439776, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71995724, Length=357, Percent_Identity=24.3697478991597, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71987143, Length=349, Percent_Identity=23.4957020057307, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17553716, Length=354, Percent_Identity=24.2937853107345, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17508543, Length=149, Percent_Identity=28.8590604026846, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323844, Length=556, Percent_Identity=37.9496402877698, Blast_Score=365, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320041, Length=337, Percent_Identity=25.2225519287834, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322912, Length=324, Percent_Identity=23.7654320987654, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322323, Length=324, Percent_Identity=23.7654320987654, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320224, Length=352, Percent_Identity=19.8863636363636, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325138, Length=127, Percent_Identity=28.3464566929134, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24646066, Length=636, Percent_Identity=37.4213836477987, Blast_Score=390, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24664226, Length=562, Percent_Identity=34.6975088967972, Blast_Score=296, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24664230, Length=454, Percent_Identity=37.6651982378855, Blast_Score=292, Evalue=5e-79,
Organism=Drosophila melanogaster, GI62472181, Length=454, Percent_Identity=37.6651982378855, Blast_Score=292, Evalue=5e-79,
Organism=Drosophila melanogaster, GI21358123, Length=355, Percent_Identity=37.1830985915493, Blast_Score=225, Evalue=6e-59,
Organism=Drosophila melanogaster, GI24645031, Length=357, Percent_Identity=23.8095238095238, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28574962, Length=345, Percent_Identity=23.4782608695652, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582080, Length=324, Percent_Identity=24.0740740740741, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24582078, Length=324, Percent_Identity=24.0740740740741, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17136248, Length=324, Percent_Identity=24.0740740740741, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24582075, Length=324, Percent_Identity=24.0740740740741, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17977678, Length=102, Percent_Identity=36.2745098039216, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24666101, Length=133, Percent_Identity=29.3233082706767, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21355075, Length=376, Percent_Identity=22.0744680851064, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 66903; Mature: 66772

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHETLAVLRTVFGYRSFRPFQEEIVDRVARGGDTFVLMPTGGGKSLCYQIPSLVRPGVG
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCH
IVISPLISLMKDQVDALRENGVAAACYNSTLGERESRRVLARLHGGELDLLYVAPERLMT
HHHHHHHHHHHHHHHHHHHCCCEEEECCCHHCCHHHHHHHHHHCCCCEEEEEECHHHHHH
DAFLERLREIPIALFAIDEAHCVSQWGHDFRPEYVELGRLRGLFPTVPMIALTATADAQT
HHHHHHHHHCCEEEEEECHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHEEEECCCCCH
RGDIVTRLGLRDAEMFVTGFDRPNIRYSVLEKQKPFRQLEEFLATRPREAGIVYCLSRKR
HHHHHHHCCCCCHHHEEEECCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCEEEEHHHHH
VEEVAEKLRAAGVEAGAYHAGLADAERSRVQEAFLRDDIRVVVATVAFGMGIDKPNVRFV
HHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
VHYDLPKNIESYYQETGRAGRDGLPAEALLLFGYGDIPVSRSLIESGGNPEQVRIELHKL
EEECCCHHHHHHHHHHCCCCCCCCCHHEEEEEECCCCCHHHHHHHCCCCCCCEEEEHHHH
NAMVGFAEALVCRRRALLGYFGERLEEPCGNCDLCLAPPETFDATEEARKALSCVYRVGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHH
RFGVGHVIDVLRGSRSERILALGHDRLSTYGIGASLAAEAWGSIIRQLIHRGYLEQDLAN
HCCHHHHHHHHHCCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCC
YSVLKLTPAARPLLRGEESLVLAKPRLRMAAPKKEKAPRRPGAATPAERDEELFQELRAL
CEEEEECCCHHHHHCCCCCEEEECCCHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHH
RKRLADDQQVPPYIIFSDATLAEMASLRPTTPEELLRVNGVGERKLGRYGAPFLEAIRSH
HHHCCCCCCCCCEEEECCCHHHHHHHCCCCCHHHHHHHCCCCCHHHCCCCCHHHHHHHHC
GAG
CCC
>Mature Secondary Structure 
GHETLAVLRTVFGYRSFRPFQEEIVDRVARGGDTFVLMPTGGGKSLCYQIPSLVRPGVG
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCH
IVISPLISLMKDQVDALRENGVAAACYNSTLGERESRRVLARLHGGELDLLYVAPERLMT
HHHHHHHHHHHHHHHHHHHCCCEEEECCCHHCCHHHHHHHHHHCCCCEEEEEECHHHHHH
DAFLERLREIPIALFAIDEAHCVSQWGHDFRPEYVELGRLRGLFPTVPMIALTATADAQT
HHHHHHHHHCCEEEEEECHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHEEEECCCCCH
RGDIVTRLGLRDAEMFVTGFDRPNIRYSVLEKQKPFRQLEEFLATRPREAGIVYCLSRKR
HHHHHHHCCCCCHHHEEEECCCCCCCHHHHHHCCHHHHHHHHHHCCCCCCCEEEEHHHHH
VEEVAEKLRAAGVEAGAYHAGLADAERSRVQEAFLRDDIRVVVATVAFGMGIDKPNVRFV
HHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
VHYDLPKNIESYYQETGRAGRDGLPAEALLLFGYGDIPVSRSLIESGGNPEQVRIELHKL
EEECCCHHHHHHHHHHCCCCCCCCCHHEEEEEECCCCCHHHHHHHCCCCCCCEEEEHHHH
NAMVGFAEALVCRRRALLGYFGERLEEPCGNCDLCLAPPETFDATEEARKALSCVYRVGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHH
RFGVGHVIDVLRGSRSERILALGHDRLSTYGIGASLAAEAWGSIIRQLIHRGYLEQDLAN
HCCHHHHHHHHHCCCCCEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCC
YSVLKLTPAARPLLRGEESLVLAKPRLRMAAPKKEKAPRRPGAATPAERDEELFQELRAL
CEEEEECCCHHHHHCCCCCEEEECCCHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHH
RKRLADDQQVPPYIIFSDATLAEMASLRPTTPEELLRVNGVGERKLGRYGAPFLEAIRSH
HHHCCCCCCCCCEEEECCCHHHHHHHCCCCCHHHHHHHCCCCCHHHCCCCCHHHHHHHHC
GAG
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]