| Definition | Geobacter sulfurreducens PCA chromosome, complete genome. |
|---|---|
| Accession | NC_002939 |
| Length | 3,814,139 |
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The map label for this gene is fabG [C]
Identifier: 39995802
GI number: 39995802
Start: 735947
End: 736705
Strand: Direct
Name: fabG [C]
Synonym: GSU0696
Alternate gene names: 39995802
Gene position: 735947-736705 (Clockwise)
Preceding gene: 39995799
Following gene: 39995804
Centisome position: 19.3
GC content: 68.25
Gene sequence:
>759_bases ATGCCGCTCAAGGGAAAGGTTGCCGTAGTTACCGGGGGAGCCCAGGGAATCGGCAAGGCGGTCGTGAAGAAGCTGATGGA AAAGGGATGCGCCGTGGTCATGGCCGACACGGACTGGGAGGCCGGGGAGGAAACGGCCGCCGGGTTCGCCGGACTCGGCC GGGTCCTGTTCGTTCCCGCCGACGTGGGCCGGGAGGACGATGTCCGCGTGCTCGTGGAGCGGGCGGCGTCGCATTTCGGC AGGCTGGACATCCTGGTCTGCAATGCCGGCGTCTTCCGGAGCGTTCCCCTGGAGCACTGTTCCCTGGACGAATGGCAGAG GCTAATCGGCACCAATCTGACCGGCGCCTTTCTCTGCGCGAAGCACGCTGCACCGTTCCTGGCGTGCCACGGCGGCAGCA TCGTCACCATCGCCTCCACCCGGGCATTCATGTCCGAGCCCGACACCGAGGCCTACGCCGCGTCCAAGGGGGGGCTGGTG GCGCTCACCCATGCCCTGGCCGTTTCCCTCGGCCCCGGCGTGCGGGTGAACTGCATCTCTCCCGGCTGGATCGAGACCTG CGAGTGGCAGAAGGCGAGCCGTCGCCGGCCCGCGGCACATTCGGAGGAGGACCGGAGCCAGCACCCCGCCGGCCGGGTCG GCACGCCGGAGGATGTGGCATCCCTGGCGGCGTGGCTGGTCTCGCCCGAGGCGGGATTCGTCACCGGCGTCAATTTCGTG GTGGACGGGGGAATGACGCGGAAGATGGTGTACGTGTAA
Upstream 100 bases:
>100_bases GCCCGGTCAATGGTAGCAGAAGATCGGGGAAAAACAGAGAACCAAAATGGAGTACAATTGTCTGGCAGCGCACTGCGAAA ACCAGCGTGAGGGGGGTGTC
Downstream 100 bases:
>100_bases CTCTCAGCCGATTTCCACGATCTTTCCTCCCGGCAGGAGCCGGAAGAGGTTGCCGCGCCAGCGGACCCGGTTGCCGGCGA AGGAGAGGGCCCAGGTGGCG
Product: glucose 1-dehydrogenase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 252; Mature: 251
Protein sequence:
>252_residues MPLKGKVAVVTGGAQGIGKAVVKKLMEKGCAVVMADTDWEAGEETAAGFAGLGRVLFVPADVGREDDVRVLVERAASHFG RLDILVCNAGVFRSVPLEHCSLDEWQRLIGTNLTGAFLCAKHAAPFLACHGGSIVTIASTRAFMSEPDTEAYAASKGGLV ALTHALAVSLGPGVRVNCISPGWIETCEWQKASRRRPAAHSEEDRSQHPAGRVGTPEDVASLAAWLVSPEAGFVTGVNFV VDGGMTRKMVYV
Sequences:
>Translated_252_residues MPLKGKVAVVTGGAQGIGKAVVKKLMEKGCAVVMADTDWEAGEETAAGFAGLGRVLFVPADVGREDDVRVLVERAASHFG RLDILVCNAGVFRSVPLEHCSLDEWQRLIGTNLTGAFLCAKHAAPFLACHGGSIVTIASTRAFMSEPDTEAYAASKGGLV ALTHALAVSLGPGVRVNCISPGWIETCEWQKASRRRPAAHSEEDRSQHPAGRVGTPEDVASLAAWLVSPEAGFVTGVNFV VDGGMTRKMVYV >Mature_251_residues PLKGKVAVVTGGAQGIGKAVVKKLMEKGCAVVMADTDWEAGEETAAGFAGLGRVLFVPADVGREDDVRVLVERAASHFGR LDILVCNAGVFRSVPLEHCSLDEWQRLIGTNLTGAFLCAKHAAPFLACHGGSIVTIASTRAFMSEPDTEAYAASKGGLVA LTHALAVSLGPGVRVNCISPGWIETCEWQKASRRRPAAHSEEDRSQHPAGRVGTPEDVASLAAWLVSPEAGFVTGVNFVV DGGMTRKMVYV
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=36.7588932806324, Blast_Score=139, Evalue=2e-33, Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=35.2941176470588, Blast_Score=125, Evalue=3e-29, Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=36.8421052631579, Blast_Score=124, Evalue=8e-29, Organism=Homo sapiens, GI5031737, Length=256, Percent_Identity=32.03125, Blast_Score=115, Evalue=3e-26, Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=32.1705426356589, Blast_Score=114, Evalue=8e-26, Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=33.4710743801653, Blast_Score=108, Evalue=6e-24, Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=34.1836734693878, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=32.1705426356589, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=32.4, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=30, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=32.3232323232323, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI83715985, Length=183, Percent_Identity=33.879781420765, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=33.1521739130435, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=27.8225806451613, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=27.4193548387097, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=28.8, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI25282469, Length=213, Percent_Identity=25.8215962441315, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI142976729, Length=188, Percent_Identity=28.7234042553192, Blast_Score=70, Evalue=2e-12, Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=32.2709163346614, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=34.1463414634146, Blast_Score=120, Evalue=1e-28, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=34.9206349206349, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=32.520325203252, Blast_Score=115, Evalue=4e-27, Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=33.8645418326693, Blast_Score=111, Evalue=5e-26, Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=30.7377049180328, Blast_Score=100, Evalue=7e-23, Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=30.4878048780488, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=32.2834645669291, Blast_Score=97, Evalue=8e-22, Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=31.6872427983539, Blast_Score=94, Evalue=7e-21, Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=31.8725099601594, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1789378, Length=238, Percent_Identity=28.9915966386555, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1789057, Length=262, Percent_Identity=27.8625954198473, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1787526, Length=252, Percent_Identity=24.6031746031746, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787820, Length=226, Percent_Identity=26.1061946902655, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=32.4110671936759, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=32.0158102766798, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=31.3008130081301, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17538182, Length=256, Percent_Identity=28.90625, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI25147288, Length=257, Percent_Identity=31.9066147859922, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=30.7984790874525, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=27.2357723577236, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=27.1255060728745, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=31.0077519379845, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=30.6513409961686, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=29.0076335877863, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17562904, Length=271, Percent_Identity=29.1512915129151, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=30.8270676691729, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=27.3764258555133, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=31.0344827586207, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=28.0769230769231, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=27.8195488721804, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=30.0380228136882, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=31.3253012048193, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17508651, Length=257, Percent_Identity=29.5719844357977, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=30.1204819277108, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=25.8555133079848, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=27.9693486590038, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=25.3787878787879, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=28.0769230769231, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=25.8555133079848, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=27.1794871794872, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17564282, Length=203, Percent_Identity=26.1083743842365, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI193203117, Length=203, Percent_Identity=24.1379310344828, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI193203115, Length=201, Percent_Identity=24.3781094527363, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=32.1285140562249, Blast_Score=119, Evalue=5e-28, Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=27.6041666666667, Blast_Score=71, Evalue=2e-13, Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=37.0517928286853, Blast_Score=139, Evalue=2e-33, Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=34.6613545816733, Blast_Score=124, Evalue=6e-29, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=32.1285140562249, Blast_Score=124, Evalue=6e-29, Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=33.6032388663968, Blast_Score=121, Evalue=5e-28, Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=31.9838056680162, Blast_Score=119, Evalue=1e-27, Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=32.6612903225806, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI17737361, Length=198, Percent_Identity=33.8383838383838, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI24644337, Length=192, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI18859837, Length=186, Percent_Identity=29.5698924731183, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=25.130890052356, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24649181, Length=191, Percent_Identity=27.7486910994764, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24665243, Length=177, Percent_Identity=30.5084745762712, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI221331218, Length=177, Percent_Identity=30.5084745762712, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI281364892, Length=191, Percent_Identity=27.2251308900524, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24641232, Length=199, Percent_Identity=28.643216080402, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 26527; Mature: 26395
Theoretical pI: Translated: 6.86; Mature: 6.86
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.8 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 5.2 %Cys+Met (Translated Protein) 2.8 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 4.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPLKGKVAVVTGGAQGIGKAVVKKLMEKGCAVVMADTDWEAGEETAAGFAGLGRVLFVPA CCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCEEEEEEC DVGREDDVRVLVERAASHFGRLDILVCNAGVFRSVPLEHCSLDEWQRLIGTNLTGAFLCA CCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHCCCCCCCCHHHHHHHHCCCCCHHHHHH KHAAPFLACHGGSIVTIASTRAFMSEPDTEAYAASKGGLVALTHALAVSLGPGVRVNCIS HHCCCEEEECCCCEEEEECCHHHHCCCCCHHHHCCCCCEEEEHHHHHHHCCCCCEEEEEC PGWIETCEWQKASRRRPAAHSEEDRSQHPAGRVGTPEDVASLAAWLVSPEAGFVTGVNFV CCCCCCCCHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEECEEEE VDGGMTRKMVYV EECCCCEEEEEC >Mature Secondary Structure PLKGKVAVVTGGAQGIGKAVVKKLMEKGCAVVMADTDWEAGEETAAGFAGLGRVLFVPA CCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCEEEEEEC DVGREDDVRVLVERAASHFGRLDILVCNAGVFRSVPLEHCSLDEWQRLIGTNLTGAFLCA CCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHCCCCCCCCHHHHHHHHCCCCCHHHHHH KHAAPFLACHGGSIVTIASTRAFMSEPDTEAYAASKGGLVALTHALAVSLGPGVRVNCIS HHCCCEEEECCCCEEEEECCHHHHCCCCCHHHHCCCCCEEEEHHHHHHHCCCCCEEEEEC PGWIETCEWQKASRRRPAAHSEEDRSQHPAGRVGTPEDVASLAAWLVSPEAGFVTGVNFV CCCCCCCCHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEECEEEE VDGGMTRKMVYV EECCCCEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7934833; 10984043 [H]