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The map label for this gene is hlyB [H]

Identifier: 39995509

GI number: 39995509

Start: 432601

End: 434220

Strand: Direct

Name: hlyB [H]

Synonym: GSU0401

Alternate gene names: 39995509

Gene position: 432601-434220 (Clockwise)

Preceding gene: 39995508

Following gene: 39995510

Centisome position: 11.34

GC content: 59.57

Gene sequence:

>1620_bases
ATGCAACTGACGATCAAGCAGAGAATGGGGATGACGGTAGGAGTTACCCTGCTGGGTATGGTGGTCATCATTGTGTTCAT
GGTTGTCGGCTTCACCAAGGTCCACCGACAGCAGGAGCTCATGGACCGGCTCACCCTGATCAATAATACGGCATTGCGCG
GCAACATTGCCATGCTTAAGGCCAGGGAATATGAGGCCGAGTTCTTTGACCGCAAGCAGGACAAGTGGGTTCCGCGGGTC
AAGCAAGCGGTTGACCAGGTCAACAAGGAACTGGACGTCATCCTCAAGAATACGGATGATCCAAAAATCAAGGGGTGGGC
CGAAAGCGCGCGCAAGCTCGCTACCCAGTATGTGCAGCAGTTCCAGGAGCTTGCATCCGTGGCCCTGGGAAGCAACTTCC
AGGGGGCGGAACTGGCCGAAACCCGGGAAGAACTGCGTGATATCCTTAACGAGTTCGAACCCCTGCTCGACAATTACATT
CCCAAGCAGGTGGGAGTCGCCTATCAGGCTGCCACCGAGGAGATGGACAGGAGCATTGCCGCCATCCGCCTTCAGATCTT
CGGCGCCGTGCTGCTGGTGGCCGTGGCCATGCTCGTCAGCATTTCGTCCACCGCCATTTACCTTCTCAGGTCCCTTCGGT
TGATCAATGACCGTCTGCGCGACATTGCCGACGGCGACGGCGACCTGACCAAGCGAATTGAACTCCAGTCCAGGGACGAG
CTGGGAACCCTGGCCGTTTCGTTCAACAATTTCGTGGGAAAGCTTCACGACATTATTGCTCAGGTTTCCCAGGGCACCCT
CCAGGTGGCGTCGGCTTCCTACGAACTCCAGGCCAACGCGGAGCAAATGGCCCACGGTGCAGAGGCGGCAGCCACACAGG
TGAACACCGTTGCCTCGTCCAGCGAGGTGCTGGCGGCATCAACCTTTGAGATATCAAGCAACTGCGGCACTGTTGCCGAA
AGCTCCCGGCGGGCCAACGACTCCGCCCAGACCGGTGCGGTCGTTGTCGAGAAGACTGTCGATATCATGGCCAGGATCGC
CGAGCGGGTCAAAGACTCGGCCCGGACCGTGGAAAGTCTGGGTGCCCGCGGCAACCAGATCGGAGAGATTATTTCCACCA
TCGAGGATATCGCCGATCAGACGAACCTGCTGGCCCTGAACGCCGCGATCGAGGCGGCTCGGGCCGGTGAGCAGGGCCGC
GGTTTTGCCGTTGTGGCGGACGAGGTGCGGGCGCTTGCCGAGCGGACATCCCGGGCTACGCGAGAGATTTCCCAGATGAT
CAAAGGGATTCAGGGCGAGACCAGGGGGGCGGTGCTTGCCATGGAGCAGGGGGTCAAAGAGGTGGAACTCGGCTCCGAGG
AGGCCGCCCGCTCCGGCGAGGCGATACGAACCATTCTCGAGCAGTTCCGTACGCTCGACTGTCAGGTGGGGGAAATTTCC
GCAGCTGCCGAGGACCAGACCCGTGTCACCACTGAAATCAGCACTAATGTCATGCAGATAACCGAGATTATCGAGACCAC
GGCAAAGGGTGCCGCTGACTCGGCCGAGGCGGCCCAAGGGTTGGCTGAGCTTTCGGATCAGCTCAAGCAGATCGTCGGAC
GATTCAAACTCAGCGTCTGA

Upstream 100 bases:

>100_bases
TTCCATTCGGTGTCTTCGCGATGGTCGGAATAGTACGCTAAATGGCGGAGCGTATTACCGTATACGTCACCGGTAAAATG
CCGCGGAGGAGATGCCTGCA

Downstream 100 bases:

>100_bases
TCGCCGCGCTTCCGGAGCCCCTCAATGAACTGTCGAGGGGCTCCGGTCGTTTTATATGGGTACTTCCTGATCGAGGGCCG
GTACATTGTTCCACTACGAC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MQLTIKQRMGMTVGVTLLGMVVIIVFMVVGFTKVHRQQELMDRLTLINNTALRGNIAMLKAREYEAEFFDRKQDKWVPRV
KQAVDQVNKELDVILKNTDDPKIKGWAESARKLATQYVQQFQELASVALGSNFQGAELAETREELRDILNEFEPLLDNYI
PKQVGVAYQAATEEMDRSIAAIRLQIFGAVLLVAVAMLVSISSTAIYLLRSLRLINDRLRDIADGDGDLTKRIELQSRDE
LGTLAVSFNNFVGKLHDIIAQVSQGTLQVASASYELQANAEQMAHGAEAAATQVNTVASSSEVLAASTFEISSNCGTVAE
SSRRANDSAQTGAVVVEKTVDIMARIAERVKDSARTVESLGARGNQIGEIISTIEDIADQTNLLALNAAIEAARAGEQGR
GFAVVADEVRALAERTSRATREISQMIKGIQGETRGAVLAMEQGVKEVELGSEEAARSGEAIRTILEQFRTLDCQVGEIS
AAAEDQTRVTTEISTNVMQITEIIETTAKGAADSAEAAQGLAELSDQLKQIVGRFKLSV

Sequences:

>Translated_539_residues
MQLTIKQRMGMTVGVTLLGMVVIIVFMVVGFTKVHRQQELMDRLTLINNTALRGNIAMLKAREYEAEFFDRKQDKWVPRV
KQAVDQVNKELDVILKNTDDPKIKGWAESARKLATQYVQQFQELASVALGSNFQGAELAETREELRDILNEFEPLLDNYI
PKQVGVAYQAATEEMDRSIAAIRLQIFGAVLLVAVAMLVSISSTAIYLLRSLRLINDRLRDIADGDGDLTKRIELQSRDE
LGTLAVSFNNFVGKLHDIIAQVSQGTLQVASASYELQANAEQMAHGAEAAATQVNTVASSSEVLAASTFEISSNCGTVAE
SSRRANDSAQTGAVVVEKTVDIMARIAERVKDSARTVESLGARGNQIGEIISTIEDIADQTNLLALNAAIEAARAGEQGR
GFAVVADEVRALAERTSRATREISQMIKGIQGETRGAVLAMEQGVKEVELGSEEAARSGEAIRTILEQFRTLDCQVGEIS
AAAEDQTRVTTEISTNVMQITEIIETTAKGAADSAEAAQGLAELSDQLKQIVGRFKLSV
>Mature_539_residues
MQLTIKQRMGMTVGVTLLGMVVIIVFMVVGFTKVHRQQELMDRLTLINNTALRGNIAMLKAREYEAEFFDRKQDKWVPRV
KQAVDQVNKELDVILKNTDDPKIKGWAESARKLATQYVQQFQELASVALGSNFQGAELAETREELRDILNEFEPLLDNYI
PKQVGVAYQAATEEMDRSIAAIRLQIFGAVLLVAVAMLVSISSTAIYLLRSLRLINDRLRDIADGDGDLTKRIELQSRDE
LGTLAVSFNNFVGKLHDIIAQVSQGTLQVASASYELQANAEQMAHGAEAAATQVNTVASSSEVLAASTFEISSNCGTVAE
SSRRANDSAQTGAVVVEKTVDIMARIAERVKDSARTVESLGARGNQIGEIISTIEDIADQTNLLALNAAIEAARAGEQGR
GFAVVADEVRALAERTSRATREISQMIKGIQGETRGAVLAMEQGVKEVELGSEEAARSGEAIRTILEQFRTLDCQVGEIS
AAAEDQTRVTTEISTNVMQITEIIETTAKGAADSAEAAQGLAELSDQLKQIVGRFKLSV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=424, Percent_Identity=29.0094339622642, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1788195, Length=331, Percent_Identity=33.2326283987915, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI2367378, Length=299, Percent_Identity=34.1137123745819, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788194, Length=369, Percent_Identity=29.2682926829268, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1789453, Length=341, Percent_Identity=28.1524926686217, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58564; Mature: 58564

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTIKQRMGMTVGVTLLGMVVIIVFMVVGFTKVHRQQELMDRLTLINNTALRGNIAMLK
CCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEE
AREYEAEFFDRKQDKWVPRVKQAVDQVNKELDVILKNTDDPKIKGWAESARKLATQYVQQ
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHH
FQELASVALGSNFQGAELAETREELRDILNEFEPLLDNYIPKQVGVAYQAATEEMDRSIA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AIRLQIFGAVLLVAVAMLVSISSTAIYLLRSLRLINDRLRDIADGDGDLTKRIELQSRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
LGTLAVSFNNFVGKLHDIIAQVSQGTLQVASASYELQANAEQMAHGAEAAATQVNTVASS
HHHHEEHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHCCHHHHHCCHHHHHHHHHHHHCC
SEVLAASTFEISSNCGTVAESSRRANDSAQTGAVVVEKTVDIMARIAERVKDSARTVESL
CCHHEEEEEEECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GARGNQIGEIISTIEDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAERTSRAT
CCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHH
REISQMIKGIQGETRGAVLAMEQGVKEVELGSEEAARSGEAIRTILEQFRTLDCQVGEIS
HHHHHHHHCCCCCCCCHHHHHHHCCHHHHCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCC
AAAEDQTRVTTEISTNVMQITEIIETTAKGAADSAEAAQGLAELSDQLKQIVGRFKLSV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLTIKQRMGMTVGVTLLGMVVIIVFMVVGFTKVHRQQELMDRLTLINNTALRGNIAMLK
CCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEE
AREYEAEFFDRKQDKWVPRVKQAVDQVNKELDVILKNTDDPKIKGWAESARKLATQYVQQ
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHH
FQELASVALGSNFQGAELAETREELRDILNEFEPLLDNYIPKQVGVAYQAATEEMDRSIA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AIRLQIFGAVLLVAVAMLVSISSTAIYLLRSLRLINDRLRDIADGDGDLTKRIELQSRDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
LGTLAVSFNNFVGKLHDIIAQVSQGTLQVASASYELQANAEQMAHGAEAAATQVNTVASS
HHHHEEHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHCCHHHHHCCHHHHHHHHHHHHCC
SEVLAASTFEISSNCGTVAESSRRANDSAQTGAVVVEKTVDIMARIAERVKDSARTVESL
CCHHEEEEEEECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GARGNQIGEIISTIEDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAERTSRAT
CCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHH
REISQMIKGIQGETRGAVLAMEQGVKEVELGSEEAARSGEAIRTILEQFRTLDCQVGEIS
HHHHHHHHCCCCCCCCHHHHHHHCCHHHHCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCC
AAAEDQTRVTTEISTNVMQITEIIETTAKGAADSAEAAQGLAELSDQLKQIVGRFKLSV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]