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The map label for this gene is mcp4 [H]

Identifier: 39995508

GI number: 39995508

Start: 430815

End: 432464

Strand: Direct

Name: mcp4 [H]

Synonym: GSU0400

Alternate gene names: 39995508

Gene position: 430815-432464 (Clockwise)

Preceding gene: 39995507

Following gene: 39995509

Centisome position: 11.3

GC content: 62.42

Gene sequence:

>1650_bases
ATGCAGATCAAGCGATACCGCAACTGGGGCATCCTGCCGAAGATCATGACCATCTCCGGTATTACGGTCGTTCTCATCGC
AGCTCTCGTCCTTTTCGTACTTCTGCCGCTCATCGGCGAGAAGATGATGGACGGCAAGAAGGAGAAAACAAAGAGTGTGG
TCGAGGTGGCCTACAACCTCGTGGCCGACCTGGGAGAACGCGCCAAGCGCGGGGAGATCTCCGAGGAAGAGGCCCGGAAA
CGGGCCATCGACCATGTCAAGCAACTCCGCTATCAGGGCAAGGAGTATTTCTGGATCAACGACCTGACGCCCAGGATGAT
CATGCACCCGATCAAGCCCGAACTGGACGGCACGGACCTGTCTGAGAACAAGGATCCGCGCGGCACCTACCTCTTCCGCG
AGTTTGCCAATATCTGCCGGGAGAAGGGAGAGGGGTTCGTCCCCTATCTCTGGCCCAAGCCGGGAGCCAGCGAACCAGTG
GAAAAAATCTCGTACGTGAAGTTGTACGAACCTTGGGGATGGGTCATTGGCAGCGGCATCTACGTGGATGACGTGCGTGC
CGACATGGCCAGGCTCCGTTGGGTAGTGCTGGGTGGGACGGCGCTCTTTGGCCTGTTTGCCCTATCGCTGGCCTTTTCCG
TGGGGCTCGGCGTGGTTCGGCCCCTGCGGCACGCGGTGACCAGCCTGCAGGATATCGCCGAGGGAGAGGGGGACCTGACC
CGGCGGATCGCGGTGGAGCGGGAAGACGAGTCAGGCGAACTGGCCCTCGCCTTCAACAGGTTTGTGGAGAAACTCCAGGG
TATCGTGGGTACGGTTGCCAACAATGCCCTGCAGGTGGCCGCTGCGGCGGGCCAAGTCCAGGAGGCGTCGCGCCAGATGG
CGGAAGCGGCAGAGAATGTGGCCGGTCAGGCAGCCACCGTGGCAACGGCCAGCGAGGAGATGGCCGCCACGAGTATGGAA
ATCGCCGGTAACTGCGTCTCACTTGCCGACGGCGCCCGTCATGCGAGCGAAACGGCCGAGAGCGGAGCTGCGGTGGTCCA
GGAGACCGTTAGCGTCATGGGGCGCATCGCCGAGCGGGTCAAGGAGGCGGCCCGTACGGTTGACAGCCTCGGTTCCCGTA
GCGACCAGATCGGGGAGATCATCGGCACGATCGAGGATATTGCCGACCAGACGAATCTTCTGGCCCTCAATGCCGCCATT
GAAGCGGCGCGGGCGGGTGAATCGGGTCGCGGCTTCGCGGTAGTAGCCGACGAGGTTCGGGCGTTGGCCGAGCGGACCAC
CCGGGCTACCCGCGAGATCGCCCTGATGATCAAGGCGATCCAGAACGAAACCCGCGGGGCAGTGGCATCCATGGATGAAG
GAGTGCGCGAGGTGGAAAAGGGCACGGGCGAGGCGGCCCGTTCGGGGGCTGCTCTGCGGGAAATCCTGGAGCAGATCGGC
TCGGTTTCGCTCCAGATCAGCCAGATAGCCACCGCGGCCGAGCAACAGACCTCCACCACCACCGAAATCAGCGGCAGCAT
CCAGACCATCACCGATACGGCCCATGAAACCGCACGCGGTGCGCAGGAATCTGCCGGAGCCGCAGGGCAGCTCGCAGATT
TGGCTGAACAATTGCAAAATGTTGTCATGACATTCCGGCTTTCAGCATGA

Upstream 100 bases:

>100_bases
TCAGCTAAAGTCACAGCCATTTTGGTCGATACTAACTTGTACGCACCCTTAGGGAATACGTCTGTCGTCCGGCCGGCGCC
GGAGCGAAAAGGAGTCGTTC

Downstream 100 bases:

>100_bases
CAAAGAGCAGTAACCGGGCATGATTGCATGCCGCAGTTCCATTCGGTGTCTTCGCGATGGTCGGAATAGTACGCTAAATG
GCGGAGCGTATTACCGTATA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MQIKRYRNWGILPKIMTISGITVVLIAALVLFVLLPLIGEKMMDGKKEKTKSVVEVAYNLVADLGERAKRGEISEEEARK
RAIDHVKQLRYQGKEYFWINDLTPRMIMHPIKPELDGTDLSENKDPRGTYLFREFANICREKGEGFVPYLWPKPGASEPV
EKISYVKLYEPWGWVIGSGIYVDDVRADMARLRWVVLGGTALFGLFALSLAFSVGLGVVRPLRHAVTSLQDIAEGEGDLT
RRIAVEREDESGELALAFNRFVEKLQGIVGTVANNALQVAAAAGQVQEASRQMAEAAENVAGQAATVATASEEMAATSME
IAGNCVSLADGARHASETAESGAAVVQETVSVMGRIAERVKEAARTVDSLGSRSDQIGEIIGTIEDIADQTNLLALNAAI
EAARAGESGRGFAVVADEVRALAERTTRATREIALMIKAIQNETRGAVASMDEGVREVEKGTGEAARSGAALREILEQIG
SVSLQISQIATAAEQQTSTTTEISGSIQTITDTAHETARGAQESAGAAGQLADLAEQLQNVVMTFRLSA

Sequences:

>Translated_549_residues
MQIKRYRNWGILPKIMTISGITVVLIAALVLFVLLPLIGEKMMDGKKEKTKSVVEVAYNLVADLGERAKRGEISEEEARK
RAIDHVKQLRYQGKEYFWINDLTPRMIMHPIKPELDGTDLSENKDPRGTYLFREFANICREKGEGFVPYLWPKPGASEPV
EKISYVKLYEPWGWVIGSGIYVDDVRADMARLRWVVLGGTALFGLFALSLAFSVGLGVVRPLRHAVTSLQDIAEGEGDLT
RRIAVEREDESGELALAFNRFVEKLQGIVGTVANNALQVAAAAGQVQEASRQMAEAAENVAGQAATVATASEEMAATSME
IAGNCVSLADGARHASETAESGAAVVQETVSVMGRIAERVKEAARTVDSLGSRSDQIGEIIGTIEDIADQTNLLALNAAI
EAARAGESGRGFAVVADEVRALAERTTRATREIALMIKAIQNETRGAVASMDEGVREVEKGTGEAARSGAALREILEQIG
SVSLQISQIATAAEQQTSTTTEISGSIQTITDTAHETARGAQESAGAAGQLADLAEQLQNVVMTFRLSA
>Mature_549_residues
MQIKRYRNWGILPKIMTISGITVVLIAALVLFVLLPLIGEKMMDGKKEKTKSVVEVAYNLVADLGERAKRGEISEEEARK
RAIDHVKQLRYQGKEYFWINDLTPRMIMHPIKPELDGTDLSENKDPRGTYLFREFANICREKGEGFVPYLWPKPGASEPV
EKISYVKLYEPWGWVIGSGIYVDDVRADMARLRWVVLGGTALFGLFALSLAFSVGLGVVRPLRHAVTSLQDIAEGEGDLT
RRIAVEREDESGELALAFNRFVEKLQGIVGTVANNALQVAAAAGQVQEASRQMAEAAENVAGQAATVATASEEMAATSME
IAGNCVSLADGARHASETAESGAAVVQETVSVMGRIAERVKEAARTVDSLGSRSDQIGEIIGTIEDIADQTNLLALNAAI
EAARAGESGRGFAVVADEVRALAERTTRATREIALMIKAIQNETRGAVASMDEGVREVEKGTGEAARSGAALREILEQIG
SVSLQISQIATAAEQQTSTTTEISGSIQTITDTAHETARGAQESAGAAGQLADLAEQLQNVVMTFRLSA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=416, Percent_Identity=30.5288461538462, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI2367378, Length=365, Percent_Identity=30.4109589041096, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1788194, Length=330, Percent_Identity=31.2121212121212, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788195, Length=332, Percent_Identity=29.8192771084337, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1789453, Length=368, Percent_Identity=25.8152173913043, Blast_Score=105, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59044; Mature: 59044

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKRYRNWGILPKIMTISGITVVLIAALVLFVLLPLIGEKMMDGKKEKTKSVVEVAYNL
CCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VADLGERAKRGEISEEEARKRAIDHVKQLRYQGKEYFWINDLTPRMIMHPIKPELDGTDL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCCCCCCCCCCC
SENKDPRGTYLFREFANICREKGEGFVPYLWPKPGASEPVEKISYVKLYEPWGWVIGSGI
CCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHEEECCCCHHHCCCE
YVDDVRADMARLRWVVLGGTALFGLFALSLAFSVGLGVVRPLRHAVTSLQDIAEGEGDLT
EEHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RRIAVEREDESGELALAFNRFVEKLQGIVGTVANNALQVAAAAGQVQEASRQMAEAAENV
HHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGQAATVATASEEMAATSMEIAGNCVSLADGARHASETAESGAAVVQETVSVMGRIAERV
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEAARTVDSLGSRSDQIGEIIGTIEDIADQTNLLALNAAIEAARAGESGRGFAVVADEVR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEHHHHHH
ALAERTTRATREIALMIKAIQNETRGAVASMDEGVREVEKGTGEAARSGAALREILEQIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHC
SVSLQISQIATAAEQQTSTTTEISGSIQTITDTAHETARGAQESAGAAGQLADLAEQLQN
CCEEHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHH
VVMTFRLSA
HHHHHHCCC
>Mature Secondary Structure
MQIKRYRNWGILPKIMTISGITVVLIAALVLFVLLPLIGEKMMDGKKEKTKSVVEVAYNL
CCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VADLGERAKRGEISEEEARKRAIDHVKQLRYQGKEYFWINDLTPRMIMHPIKPELDGTDL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCCCCCCCCCCC
SENKDPRGTYLFREFANICREKGEGFVPYLWPKPGASEPVEKISYVKLYEPWGWVIGSGI
CCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHHHHHHEEECCCCHHHCCCE
YVDDVRADMARLRWVVLGGTALFGLFALSLAFSVGLGVVRPLRHAVTSLQDIAEGEGDLT
EEHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RRIAVEREDESGELALAFNRFVEKLQGIVGTVANNALQVAAAAGQVQEASRQMAEAAENV
HHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGQAATVATASEEMAATSMEIAGNCVSLADGARHASETAESGAAVVQETVSVMGRIAERV
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEAARTVDSLGSRSDQIGEIIGTIEDIADQTNLLALNAAIEAARAGESGRGFAVVADEVR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEEHHHHHH
ALAERTTRATREIALMIKAIQNETRGAVASMDEGVREVEKGTGEAARSGAALREILEQIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHC
SVSLQISQIATAAEQQTSTTTEISGSIQTITDTAHETARGAQESAGAAGQLADLAEQLQN
CCEEHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHH
VVMTFRLSA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]