| Definition | Geobacter sulfurreducens PCA chromosome, complete genome. |
|---|---|
| Accession | NC_002939 |
| Length | 3,814,139 |
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The map label for this gene is gyrB [H]
Identifier: 39995114
GI number: 39995114
Start: 3901
End: 6288
Strand: Direct
Name: gyrB [H]
Synonym: GSU0003
Alternate gene names: 39995114
Gene position: 3901-6288 (Clockwise)
Preceding gene: 39995113
Following gene: 39995115
Centisome position: 0.1
GC content: 61.31
Gene sequence:
>2388_bases ATGACCGACGAACAGAACTACGATTACGGTGCAGACAAGATCAAGGTCCTGGAGGGGCTCGAGGCGGTACGCAAGCGCCC CGCCATGTACATCGGCTCCACCGCGGCCCAGGGGCTCCACCACCTGGTCTACGAGATCGTGGACAACTCCATTGACGAGG CCCTGGCCGGCTACTGCAACGAGGTGAACGTCACCATCCATCTGGATGGTTCCCTGACGGTGGTGGACAATGGCCGCGGC ATTCCTACCGACATCCACCCCACGGAGGGGAAGCCGGCGGCGGAGGTGGCCCTCACGGTCCTCCATGCCGGCGGCAAGTT CGACAACACCTCCTATAAGGTCTCCGGCGGGCTCCACGGGGTCGGGGTCTCGGTCGTGAACGCCCTGTCCAGGAAGCTGG AGCTGGAGATTCGCCGGGACGGGAAGGTGTACCGCCAGTCCTACGCCTGCGGCGACCCCCAGACTCCCCTCGAAGTGATG GGGGAAACGAAAAAGCGTGGGACCAAAATAACCTTCCTCCCCGACGATACCATCTTCGAGACCACGGAGTTTTCCTTCGA CGTTCTTTCCCAGCGGCTCCGGGAGCTGGCGTTCCTCAACGCCGGGGTCCGGATCACCATCACCGACGAACGGGAGGAGG GAAAGCACCACGACTTTCACTACGAAGGAGGCATCGTCTCCTTTGTGGAGTACCTGAACCGCAACCGGACCGCCCTCCAC CCGAAGCCGATCTACTTCAAGGGTGAAAAGGCAGGAGTCGAGATGGAGGTGGCCCTCCAGTACAACGATTCCTATGACGA AAAGGTTTTCTCTTTTGCCAACAACATCAACACCCACGAGGGTGGAACCCACTTGGTGGGGTTCCGGGCGGCCCTCACCC GGACCATGAACACCTATGCCGCCGCCAACGAACTCCTCAAAAAGGAGAAGGTTGCCATCTCCGGCGAGGATCTGCGAGAG GGTCTCACGGCGGTCATCTCGGTCAAGATTCCCCAACCACAGTTCGAGGGGCAGACCAAGACCAAGCTGGGGAACTCGGA GGTTAAGGGGTACGTGGAATCCCTCATGAACGAGAAACTGGCGGTCTTCCTGGAAGAGAACCCGAAGATCGCCAAAGACA TCATCGGCAAATCCATCGAGGCGGCCCGTGCCCGGGAAGCGGCCCGCAAGGCGCGGGAATTGACCCGGCGCAAGGGCGCC CTGGACATCTCCAACCTTCCGGGCAAACTGGCCGACTGCCAGGAGCGGGATCCGGCCCTGTGCGAACTCTACCTGGTGGA GGGCGACTCCGCCGGCGGTTCCGCCAAACAGGGGCGCGACCGGAAATTCCAGGCCATTCTGCCGCTGAAAGGAAAGATCC TCAACGTGGAGAAGGCCCGGTTCGACAAGATGCTTTCCTCCCAGGAGATCGGGACCCTTATCACGGCGCTCGGCACCGGT ATCGGGAAAGACGACTTCGACATCGCCAAGCTCCGCTACCACCGGATCATCGTCATGACCGACGCCGACGTGGACGGCTC CCACATCCTGACGCTGCTGCTCACCTTCTTCTTCCGGCAGATGCCGGAGGTGGTGGAGCGGGGGCACCTCTACATCGCCC AGCCCCCCCTCTATAAGGTGAAGCGAGGGCGCAAGGAGCTCTATCTCCGCAATGAGGCGGCCATGCAGGCCTACCTCCTT GAGGAGGGGACCGAGGACATGCTCCTTTTTCTGGAGAGCGGCGAGAAGACCTACAGCGGCAAGCAGATCATCCCGATCCT CAAGCAGTTGGTGGAGTATCGGACCATCCTGGATAAGGTAGTGCGCAAGGGGATCAACGAGGAGCTCATACGGGTATTCC TGCGGCTCGGCGTCAAGGGGGGGATTGAGGACATGGAGCAGTTGGTGCCGTTCCTGACGAACATCTCCCGGGTCTATGAC GGCGGCGATTTCAGCCCCTTGGACGACGGGCGGGTCATCGTGCGGCTCGGCAACCTCCGGATCGCCCTGGATCAGCATAC GCTCGACCTCATCGGTTCCTACGAGTACGGGCTCCTGGTGGAGAGCTACCGAAAGGTCAGGGATATCTTCGGCGACGGCC GGGCCGTGGTCTCCAGCGAGGGTAAGGAACTCTTCGCGACCACCATCGGGCTCGACCTCCTCTCCTTCTTCATGGACAGC GCCAAGAAGGGGCTCTCCATCCAGCGCTACAAGGGTCTCGGCGAGATGAACCCGGAGCAGCTCTGGGAAACCACCATGGA GCCCGTCAACCGGACCCTGCTCCAGGTGAAGATTGAGGACGCCATCGAGGCAGACACCATATTCACCATCCTCATGGGGG ACCAGGTGGAGCCCCGCCGGGACTTCATCGAGCAGAACGCCCTGAACGTGTCGAATTTGGACATTTAG
Upstream 100 bases:
>100_bases ACCACCACCGATGTATCAACCCTCCGTCTGGAGGGGATCGACACCCACGCGTCGTTTCGCGTTTCACGTGGAACGGTGAC GCCTGTATAGAGGGAGAGGC
Downstream 100 bases:
>100_bases ACGATTATGTGAGGGGTGTGATTCATCGCGCCCGGGTGCAATGAATCACACCCCTACGGGTGCCATGCCGTTATCGGGCG AGGCATCGTCTCGACCCTAC
Product: DNA gyrase subunit B
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 795; Mature: 794
Protein sequence:
>795_residues MTDEQNYDYGADKIKVLEGLEAVRKRPAMYIGSTAAQGLHHLVYEIVDNSIDEALAGYCNEVNVTIHLDGSLTVVDNGRG IPTDIHPTEGKPAAEVALTVLHAGGKFDNTSYKVSGGLHGVGVSVVNALSRKLELEIRRDGKVYRQSYACGDPQTPLEVM GETKKRGTKITFLPDDTIFETTEFSFDVLSQRLRELAFLNAGVRITITDEREEGKHHDFHYEGGIVSFVEYLNRNRTALH PKPIYFKGEKAGVEMEVALQYNDSYDEKVFSFANNINTHEGGTHLVGFRAALTRTMNTYAAANELLKKEKVAISGEDLRE GLTAVISVKIPQPQFEGQTKTKLGNSEVKGYVESLMNEKLAVFLEENPKIAKDIIGKSIEAARAREAARKARELTRRKGA LDISNLPGKLADCQERDPALCELYLVEGDSAGGSAKQGRDRKFQAILPLKGKILNVEKARFDKMLSSQEIGTLITALGTG IGKDDFDIAKLRYHRIIVMTDADVDGSHILTLLLTFFFRQMPEVVERGHLYIAQPPLYKVKRGRKELYLRNEAAMQAYLL EEGTEDMLLFLESGEKTYSGKQIIPILKQLVEYRTILDKVVRKGINEELIRVFLRLGVKGGIEDMEQLVPFLTNISRVYD GGDFSPLDDGRVIVRLGNLRIALDQHTLDLIGSYEYGLLVESYRKVRDIFGDGRAVVSSEGKELFATTIGLDLLSFFMDS AKKGLSIQRYKGLGEMNPEQLWETTMEPVNRTLLQVKIEDAIEADTIFTILMGDQVEPRRDFIEQNALNVSNLDI
Sequences:
>Translated_795_residues MTDEQNYDYGADKIKVLEGLEAVRKRPAMYIGSTAAQGLHHLVYEIVDNSIDEALAGYCNEVNVTIHLDGSLTVVDNGRG IPTDIHPTEGKPAAEVALTVLHAGGKFDNTSYKVSGGLHGVGVSVVNALSRKLELEIRRDGKVYRQSYACGDPQTPLEVM GETKKRGTKITFLPDDTIFETTEFSFDVLSQRLRELAFLNAGVRITITDEREEGKHHDFHYEGGIVSFVEYLNRNRTALH PKPIYFKGEKAGVEMEVALQYNDSYDEKVFSFANNINTHEGGTHLVGFRAALTRTMNTYAAANELLKKEKVAISGEDLRE GLTAVISVKIPQPQFEGQTKTKLGNSEVKGYVESLMNEKLAVFLEENPKIAKDIIGKSIEAARAREAARKARELTRRKGA LDISNLPGKLADCQERDPALCELYLVEGDSAGGSAKQGRDRKFQAILPLKGKILNVEKARFDKMLSSQEIGTLITALGTG IGKDDFDIAKLRYHRIIVMTDADVDGSHILTLLLTFFFRQMPEVVERGHLYIAQPPLYKVKRGRKELYLRNEAAMQAYLL EEGTEDMLLFLESGEKTYSGKQIIPILKQLVEYRTILDKVVRKGINEELIRVFLRLGVKGGIEDMEQLVPFLTNISRVYD GGDFSPLDDGRVIVRLGNLRIALDQHTLDLIGSYEYGLLVESYRKVRDIFGDGRAVVSSEGKELFATTIGLDLLSFFMDS AKKGLSIQRYKGLGEMNPEQLWETTMEPVNRTLLQVKIEDAIEADTIFTILMGDQVEPRRDFIEQNALNVSNLDI >Mature_794_residues TDEQNYDYGADKIKVLEGLEAVRKRPAMYIGSTAAQGLHHLVYEIVDNSIDEALAGYCNEVNVTIHLDGSLTVVDNGRGI PTDIHPTEGKPAAEVALTVLHAGGKFDNTSYKVSGGLHGVGVSVVNALSRKLELEIRRDGKVYRQSYACGDPQTPLEVMG ETKKRGTKITFLPDDTIFETTEFSFDVLSQRLRELAFLNAGVRITITDEREEGKHHDFHYEGGIVSFVEYLNRNRTALHP KPIYFKGEKAGVEMEVALQYNDSYDEKVFSFANNINTHEGGTHLVGFRAALTRTMNTYAAANELLKKEKVAISGEDLREG LTAVISVKIPQPQFEGQTKTKLGNSEVKGYVESLMNEKLAVFLEENPKIAKDIIGKSIEAARAREAARKARELTRRKGAL DISNLPGKLADCQERDPALCELYLVEGDSAGGSAKQGRDRKFQAILPLKGKILNVEKARFDKMLSSQEIGTLITALGTGI GKDDFDIAKLRYHRIIVMTDADVDGSHILTLLLTFFFRQMPEVVERGHLYIAQPPLYKVKRGRKELYLRNEAAMQAYLLE EGTEDMLLFLESGEKTYSGKQIIPILKQLVEYRTILDKVVRKGINEELIRVFLRLGVKGGIEDMEQLVPFLTNISRVYDG GDFSPLDDGRVIVRLGNLRIALDQHTLDLIGSYEYGLLVESYRKVRDIFGDGRAVVSSEGKELFATTIGLDLLSFFMDSA KKGLSIQRYKGLGEMNPEQLWETTMEPVNRTLLQVKIEDAIEADTIFTILMGDQVEPRRDFIEQNALNVSNLDI
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0187
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Toprim domain [H]
Homologues:
Organism=Homo sapiens, GI19913406, Length=580, Percent_Identity=25.5172413793103, Blast_Score=135, Evalue=2e-31, Organism=Homo sapiens, GI19913408, Length=588, Percent_Identity=26.0204081632653, Blast_Score=127, Evalue=3e-29, Organism=Escherichia coli, GI48994957, Length=813, Percent_Identity=55.5965559655597, Blast_Score=835, Evalue=0.0, Organism=Escherichia coli, GI1789408, Length=555, Percent_Identity=41.6216216216216, Blast_Score=419, Evalue=1e-118, Organism=Caenorhabditis elegans, GI212645845, Length=511, Percent_Identity=27.2015655577299, Blast_Score=143, Evalue=3e-34, Organism=Caenorhabditis elegans, GI17535065, Length=578, Percent_Identity=25.2595155709343, Blast_Score=134, Evalue=2e-31, Organism=Caenorhabditis elegans, GI212645657, Length=146, Percent_Identity=32.1917808219178, Blast_Score=70, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6324241, Length=585, Percent_Identity=27.8632478632479, Blast_Score=141, Evalue=4e-34, Organism=Drosophila melanogaster, GI17136538, Length=575, Percent_Identity=25.9130434782609, Blast_Score=137, Evalue=4e-32,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR011557 - InterPro: IPR020568 - InterPro: IPR014721 - InterPro: IPR001241 - InterPro: IPR013759 - InterPro: IPR002288 - InterPro: IPR013506 - InterPro: IPR013760 - InterPro: IPR018522 - InterPro: IPR006171 [H]
Pfam domain/function: PF00204 DNA_gyraseB; PF00986 DNA_gyraseB_C; PF02518 HATPase_c; PF01751 Toprim [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 88788; Mature: 88656
Theoretical pI: Translated: 5.63; Mature: 5.63
Prosite motif: PS00177 TOPOISOMERASE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTDEQNYDYGADKIKVLEGLEAVRKRPAMYIGSTAAQGLHHLVYEIVDNSIDEALAGYCN CCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHCHHHHHHHHCCC EVNVTIHLDGSLTVVDNGRGIPTDIHPTEGKPAAEVALTVLHAGGKFDNTSYKVSGGLHG CEEEEEEECCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHEECCCCCCCCCEEECCCCCH VGVSVVNALSRKLELEIRRDGKVYRQSYACGDPQTPLEVMGETKKRGTKITFLPDDTIFE HHHHHHHHHHHHEEEEEECCCHHHHHHCCCCCCCCCHHHHCCHHHCCCEEEECCCCCEEC TTEFSFDVLSQRLRELAFLNAGVRITITDEREEGKHHDFHYEGGIVSFVEYLNRNRTALH CCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEECCCHHHHHHHHCCCCCCCC PKPIYFKGEKAGVEMEVALQYNDSYDEKVFSFANNINTHEGGTHLVGFRAALTRTMNTYA CCCEEEECCCCCEEEEEEEEECCCHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHH AANELLKKEKVAISGEDLREGLTAVISVKIPQPQFEGQTKTKLGNSEVKGYVESLMNEKL HHHHHHHHHHHEECCHHHHCCCEEEEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHCCCE AVFLEENPKIAKDIIGKSIEAARAREAARKARELTRRKGALDISNLPGKLADCQERDPAL EEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCE CELYLVEGDSAGGSAKQGRDRKFQAILPLKGKILNVEKARFDKMLSSQEIGTLITALGTG EEEEEEECCCCCCCCCCCCCCCEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCC IGKDDFDIAKLRYHRIIVMTDADVDGSHILTLLLTFFFRQMPEVVERGHLYIAQPPLYKV CCCCCCHHHEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHH KRGRKELYLRNEAAMQAYLLEEGTEDMLLFLESGEKTYSGKQIIPILKQLVEYRTILDKV HCCCHHEEECCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH VRKGINEELIRVFLRLGVKGGIEDMEQLVPFLTNISRVYDGGDFSPLDDGRVIVRLGNLR HHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCEE IALDQHTLDLIGSYEYGLLVESYRKVRDIFGDGRAVVSSEGKELFATTIGLDLLSFFMDS EEEECCHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHH AKKGLSIQRYKGLGEMNPEQLWETTMEPVNRTLLQVKIEDAIEADTIFTILMGDQVEPRR HHCCCEEHHHCCCCCCCHHHHHHHHHHHHHHHEEEEEEHHHHCCCCEEEEEECCCCCHHH DFIEQNALNVSNLDI HHHHHCCCCCCCCCC >Mature Secondary Structure TDEQNYDYGADKIKVLEGLEAVRKRPAMYIGSTAAQGLHHLVYEIVDNSIDEALAGYCN CCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHCHHHHHHHHCCC EVNVTIHLDGSLTVVDNGRGIPTDIHPTEGKPAAEVALTVLHAGGKFDNTSYKVSGGLHG CEEEEEEECCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHEECCCCCCCCCEEECCCCCH VGVSVVNALSRKLELEIRRDGKVYRQSYACGDPQTPLEVMGETKKRGTKITFLPDDTIFE HHHHHHHHHHHHEEEEEECCCHHHHHHCCCCCCCCCHHHHCCHHHCCCEEEECCCCCEEC TTEFSFDVLSQRLRELAFLNAGVRITITDEREEGKHHDFHYEGGIVSFVEYLNRNRTALH CCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEECCCHHHHHHHHCCCCCCCC PKPIYFKGEKAGVEMEVALQYNDSYDEKVFSFANNINTHEGGTHLVGFRAALTRTMNTYA CCCEEEECCCCCEEEEEEEEECCCHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHH AANELLKKEKVAISGEDLREGLTAVISVKIPQPQFEGQTKTKLGNSEVKGYVESLMNEKL HHHHHHHHHHHEECCHHHHCCCEEEEEEECCCCCCCCCHHHCCCCHHHHHHHHHHHCCCE AVFLEENPKIAKDIIGKSIEAARAREAARKARELTRRKGALDISNLPGKLADCQERDPAL EEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCE CELYLVEGDSAGGSAKQGRDRKFQAILPLKGKILNVEKARFDKMLSSQEIGTLITALGTG EEEEEEECCCCCCCCCCCCCCCEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCC IGKDDFDIAKLRYHRIIVMTDADVDGSHILTLLLTFFFRQMPEVVERGHLYIAQPPLYKV CCCCCCHHHEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHH KRGRKELYLRNEAAMQAYLLEEGTEDMLLFLESGEKTYSGKQIIPILKQLVEYRTILDKV HCCCHHEEECCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH VRKGINEELIRVFLRLGVKGGIEDMEQLVPFLTNISRVYDGGDFSPLDDGRVIVRLGNLR HHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCEE IALDQHTLDLIGSYEYGLLVESYRKVRDIFGDGRAVVSSEGKELFATTIGLDLLSFFMDS EEEECCHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHH AKKGLSIQRYKGLGEMNPEQLWETTMEPVNRTLLQVKIEDAIEADTIFTILMGDQVEPRR HHCCCEEHHHCCCCCCCHHHHHHHHHHHHHHHEEEEEEHHHHCCCCEEEEEECCCCCHHH DFIEQNALNVSNLDI HHHHHCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 10952301 [H]