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The map label for this gene is pheT

Identifier: 57234859

GI number: 57234859

Start: 346912

End: 349341

Strand: Direct

Name: pheT

Synonym: DET0366

Alternate gene names: 57234859

Gene position: 346912-349341 (Clockwise)

Preceding gene: 57234860

Following gene: 57234858

Centisome position: 23.6

GC content: 49.3

Gene sequence:

>2430_bases
ATGAAAATACCTTTGAAGTGGCTTAAAGAATATCTTCCCACAGATATGTCGCCGGCCGAACTGGCCGAACGGATGACTAT
GGCCGGTACTGAGGTGACAGTACTGAATTCCCGCAAAGATAAATGGCCGAACGTATATGTAGGCCAGATAATGGAAGTAA
ACCGTCACCCCAACGCTGACCGTTTGGTACTGGTTAAGGTGGATTGGGGGCAGGGGCAGGAGACAGTGGTTACCGGCGCG
CCTAACTGCAAAGCCGGTGACAAGGTCGTTTTTGCCCGTACCGGTGCAGTTTTGATAGATGGCCACAACGGCAAAGAAAT
GGTACTTAAGCCGGCTGTTTTGCGGGGGGTGGAATCCTGCGGAATGGTTTGTTCCGAAAGGGAATTGGGACTGTCTGACG
AACATGAGGGTATTTTGATACTGCCGGCTGATGCTCCGGTGGGTATGCTGGCCAGTGAATATCTGGGTGAGATAATACTT
GACCTTGAGCTTACACCTAACCGGGGTGATTTGATGTGTGTAACCGGTGTGGCCAGAGAACTGGGCGCTTTAATAGACCG
TTTGCCTTCTATAAGCACGCCGGATTTCAAGGCCACCGGTAAGGATATCAAGGACAAAATAAATATAGAGATAAAAAACA
CTAAACTCTGCACCCGTTATACCGCCAGCCTGATAGAGGGAATAAAAATCGGCGAATCACCGGACTGGCTTAAAGAGCGG
CTGATTGCCTGCGGTATGCGCCCGATAAACAACGTGGTAGATGCTACCAATTACGTTATGCTGGAATTCGGCCAGCCCCT
GCACTCCTTTGATTATGACCAGATTAAGTCAAAACATATTATTGTCCGCCCCGCAGCGGAGGGTGAGGTTTTAACTACTC
TGGACGGGGTTGAACGCAAACTCAGCCCGGATATGCTCCTTATTACCGAACCGGACAAAATAATTGCCCTGGCCGGGGTA
ATGGGCGGTGAAAATACCGAGGTTACTGAGAAAACTGCCAGCGTACTGCTGGAGTCGGCTACCTTTGACAAGCACAGCAT
CCGCAGGACTGCTAAAGCTTTGAAACTCCAGAGTGAGGCTTCAGCCCGTTTTGAAAAAGGGCTTAGCTTTGAGCTTGCGC
CTGTTGCCCTGAAACGCGCCACCCAGCTGATACTGGAAATAGCCGGCGGGCAGGCGGCTTCGGGCTTAATGGATGTCATG
CCGGTTAAAAAAGACAGAAACAGCGTTGTATTATCTCTTTCAAAGGTCAACCGGGTATTAGGGCTTGAGGGAGAGAAATT
TGACAGCTGTAAAATAGCCAAAAGGCTGGGTTTTGCCTGGATGCCCGAATATGTACCCGGTATGGAAGAATTCGGCTACG
GTTCCGTTGATGATAAAATGCGGTTTTTCCCCGGTTACTGGCGGATGGATATTGAAAGTGATATTGATATGATTGAGGAG
GTGGCCAGGATAGCCGGCTACGATACTATACCCTGTCTGCCTCTGGATAAAGCCATTCCTAAAATAGAAACACCCCCTCT
GCCGGGCATAAAGCGTTTCTTACGGCAGATATTATCAGGGTATGGTTTTCAGGAACTTATATCATATTCATTCACCAGCC
GCGAAATGCTTTCCCGTGTTTTTTCAGGGGCTGAGCCCGAATGTCTGGCTATCAGCAACCCCATGAGCAGTGAGCAGGAA
GTTATGCGTACCAGCTTGCGTCCTGCCCTGTATGCATCTTTAGCGGCAAACCGCCGTTTTGAAAAAAACGGCCTCAGGCT
GTATGAGCTTGGGCGCATCTACCTGCCGAAAGAGAATAATAAGCAAGATGAGCCCGAAATGCTGTGCGCCCTTATAGCGG
GCAGTGCCTCTGAAGCCTGGTGGCAGAGAAATACCGCTGGTTTTGACTTCTTTGATGCCAAAGGCATTGTGGAATCTTTG
GTCAGCCGGTTGGGTATTGCAGCTGATTTTGCGGTATCTGATGAACCGGGTCTGACTCCGGGGTATCAGGCCGGTATACT
GGTGGGAGACATGCCGGTGGGTGTTTTGGGGCAGCTAAGCCCCCAGACTGCAGATAAATTCGGCATAACAGAGCCGGTAT
ATATGTTTGAAATCAATCTTTCCAAGCTCATTACCCGGGCTACGGTTCGGCGCAAATTTACCCAGATTAACCGCTTCCCC
TCAGTGGAACGTGATTTGGCTTTGGTGCTTGACCGCAGTATTACCAACCGGCAGGTTACAGATATAATTTCCGAGTTTGA
TTTGGTTAAAAATGTAGAGCTGTTTGATATGTATCAGGGCAAGCAGGTAGCCGAGGACAAAAAATCACTGGCTTATCATC
TGCTGTTTCAGTCTGATACCCATACCCTGAAAGATGCGGATGTAGACAGTGTAATGAACCAGATACTTAAACGGCTTAAT
ACTGAAACGGGGGCGGTTCTGCGTTCCTGA

Upstream 100 bases:

>100_bases
TTTGGCATGGGGCTGGAAAGATTGCCCATGCTGAGATACGGGATTGATGATATCCGTCTGTTCTACTCTAACGATACTAG
ATTCTTGAGGCAGTTTTAAT

Downstream 100 bases:

>100_bases
GTGTATTTATCCGGTTATTGCAAAAGGGGCTTTTGGGTAGAAGCCCCTTTTGGTTTTTAAGCCCGAATGAGGTATTATAA
ATGCGGAGGAAAAATGTTAA

Product: phenylalanyl-tRNA synthetase subunit beta

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase beta chain; PheRS

Number of amino acids: Translated: 809; Mature: 809

Protein sequence:

>809_residues
MKIPLKWLKEYLPTDMSPAELAERMTMAGTEVTVLNSRKDKWPNVYVGQIMEVNRHPNADRLVLVKVDWGQGQETVVTGA
PNCKAGDKVVFARTGAVLIDGHNGKEMVLKPAVLRGVESCGMVCSERELGLSDEHEGILILPADAPVGMLASEYLGEIIL
DLELTPNRGDLMCVTGVARELGALIDRLPSISTPDFKATGKDIKDKINIEIKNTKLCTRYTASLIEGIKIGESPDWLKER
LIACGMRPINNVVDATNYVMLEFGQPLHSFDYDQIKSKHIIVRPAAEGEVLTTLDGVERKLSPDMLLITEPDKIIALAGV
MGGENTEVTEKTASVLLESATFDKHSIRRTAKALKLQSEASARFEKGLSFELAPVALKRATQLILEIAGGQAASGLMDVM
PVKKDRNSVVLSLSKVNRVLGLEGEKFDSCKIAKRLGFAWMPEYVPGMEEFGYGSVDDKMRFFPGYWRMDIESDIDMIEE
VARIAGYDTIPCLPLDKAIPKIETPPLPGIKRFLRQILSGYGFQELISYSFTSREMLSRVFSGAEPECLAISNPMSSEQE
VMRTSLRPALYASLAANRRFEKNGLRLYELGRIYLPKENNKQDEPEMLCALIAGSASEAWWQRNTAGFDFFDAKGIVESL
VSRLGIAADFAVSDEPGLTPGYQAGILVGDMPVGVLGQLSPQTADKFGITEPVYMFEINLSKLITRATVRRKFTQINRFP
SVERDLALVLDRSITNRQVTDIISEFDLVKNVELFDMYQGKQVAEDKKSLAYHLLFQSDTHTLKDADVDSVMNQILKRLN
TETGAVLRS

Sequences:

>Translated_809_residues
MKIPLKWLKEYLPTDMSPAELAERMTMAGTEVTVLNSRKDKWPNVYVGQIMEVNRHPNADRLVLVKVDWGQGQETVVTGA
PNCKAGDKVVFARTGAVLIDGHNGKEMVLKPAVLRGVESCGMVCSERELGLSDEHEGILILPADAPVGMLASEYLGEIIL
DLELTPNRGDLMCVTGVARELGALIDRLPSISTPDFKATGKDIKDKINIEIKNTKLCTRYTASLIEGIKIGESPDWLKER
LIACGMRPINNVVDATNYVMLEFGQPLHSFDYDQIKSKHIIVRPAAEGEVLTTLDGVERKLSPDMLLITEPDKIIALAGV
MGGENTEVTEKTASVLLESATFDKHSIRRTAKALKLQSEASARFEKGLSFELAPVALKRATQLILEIAGGQAASGLMDVM
PVKKDRNSVVLSLSKVNRVLGLEGEKFDSCKIAKRLGFAWMPEYVPGMEEFGYGSVDDKMRFFPGYWRMDIESDIDMIEE
VARIAGYDTIPCLPLDKAIPKIETPPLPGIKRFLRQILSGYGFQELISYSFTSREMLSRVFSGAEPECLAISNPMSSEQE
VMRTSLRPALYASLAANRRFEKNGLRLYELGRIYLPKENNKQDEPEMLCALIAGSASEAWWQRNTAGFDFFDAKGIVESL
VSRLGIAADFAVSDEPGLTPGYQAGILVGDMPVGVLGQLSPQTADKFGITEPVYMFEINLSKLITRATVRRKFTQINRFP
SVERDLALVLDRSITNRQVTDIISEFDLVKNVELFDMYQGKQVAEDKKSLAYHLLFQSDTHTLKDADVDSVMNQILKRLN
TETGAVLRS
>Mature_809_residues
MKIPLKWLKEYLPTDMSPAELAERMTMAGTEVTVLNSRKDKWPNVYVGQIMEVNRHPNADRLVLVKVDWGQGQETVVTGA
PNCKAGDKVVFARTGAVLIDGHNGKEMVLKPAVLRGVESCGMVCSERELGLSDEHEGILILPADAPVGMLASEYLGEIIL
DLELTPNRGDLMCVTGVARELGALIDRLPSISTPDFKATGKDIKDKINIEIKNTKLCTRYTASLIEGIKIGESPDWLKER
LIACGMRPINNVVDATNYVMLEFGQPLHSFDYDQIKSKHIIVRPAAEGEVLTTLDGVERKLSPDMLLITEPDKIIALAGV
MGGENTEVTEKTASVLLESATFDKHSIRRTAKALKLQSEASARFEKGLSFELAPVALKRATQLILEIAGGQAASGLMDVM
PVKKDRNSVVLSLSKVNRVLGLEGEKFDSCKIAKRLGFAWMPEYVPGMEEFGYGSVDDKMRFFPGYWRMDIESDIDMIEE
VARIAGYDTIPCLPLDKAIPKIETPPLPGIKRFLRQILSGYGFQELISYSFTSREMLSRVFSGAEPECLAISNPMSSEQE
VMRTSLRPALYASLAANRRFEKNGLRLYELGRIYLPKENNKQDEPEMLCALIAGSASEAWWQRNTAGFDFFDAKGIVESL
VSRLGIAADFAVSDEPGLTPGYQAGILVGDMPVGVLGQLSPQTADKFGITEPVYMFEINLSKLITRATVRRKFTQINRFP
SVERDLALVLDRSITNRQVTDIISEFDLVKNVELFDMYQGKQVAEDKKSLAYHLLFQSDTHTLKDADVDSVMNQILKRLN
TETGAVLRS

Specific function: Unknown

COG id: COG0072

COG function: function code J; Phenylalanyl-tRNA synthetase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 tRNA-binding domain

Homologues:

Organism=Homo sapiens, GI124028525, Length=248, Percent_Identity=27.0161290322581, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI1788006, Length=826, Percent_Identity=35.1089588377724, Blast_Score=434, Evalue=1e-122,
Organism=Drosophila melanogaster, GI21355211, Length=588, Percent_Identity=20.7482993197279, Blast_Score=73, Evalue=8e-13,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYFB_DEHE1 (Q3Z9I7)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_181112.1
- ProteinModelPortal:   Q3Z9I7
- SMR:   Q3Z9I7
- STRING:   Q3Z9I7
- GeneID:   3230328
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET0366
- NMPDR:   fig|243164.3.peg.504
- TIGR:   DET0366
- eggNOG:   COG0072
- HOGENOM:   HBG399638
- OMA:   ADKLRVC
- PhylomeDB:   Q3Z9I7
- ProtClustDB:   PRK00629
- BioCyc:   DETH243164:DET_0366-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00283
- InterPro:   IPR005146
- InterPro:   IPR005147
- InterPro:   IPR009061
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004532
- InterPro:   IPR020825
- InterPro:   IPR005121
- InterPro:   IPR002547
- Gene3D:   G3DSA:3.50.40.10
- Gene3D:   G3DSA:3.30.56.20
- Gene3D:   G3DSA:3.30.70.380
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00873
- SMART:   SM00874
- SMART:   SM00896
- TIGRFAMs:   TIGR00472

Pfam domain/function: PF03483 B3_4; PF03484 B5; PF03147 FDX-ACB; PF01588 tRNA_bind; SSF56037 B3_4; SSF54991 Fdx_AntiC_bd; SSF50249 Nucleic_acid_OB; SSF46955 Putativ_DNA_bind

EC number: =6.1.1.20

Molecular weight: Translated: 89650; Mature: 89650

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS51483 B5; PS51447 FDX_ACB; PS50886 TRBD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIPLKWLKEYLPTDMSPAELAERMTMAGTEVTVLNSRKDKWPNVYVGQIMEVNRHPNAD
CCCCHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEHHEEECCCCCCC
RLVLVKVDWGQGQETVVTGAPNCKAGDKVVFARTGAVLIDGHNGKEMVLKPAVLRGVESC
EEEEEEEECCCCCCEEEECCCCCCCCCEEEEEECCEEEEECCCCCEEEECHHHHHHHHHH
GMVCSERELGLSDEHEGILILPADAPVGMLASEYLGEIILDLELTPNRGDLMCVTGVARE
CCEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHEEEEEEECCCCCCEEEHHHHHHH
LGALIDRLPSISTPDFKATGKDIKDKINIEIKNTKLCTRYTASLIEGIKIGESPDWLKER
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHH
LIACGMRPINNVVDATNYVMLEFGQPLHSFDYDQIKSKHIIVRPAAEGEVLTTLDGVERK
HHHCCCCHHHHHHCCCCEEEEECCCCHHCCCHHHHCCCEEEEEECCCCCEEEHHHHHHHH
LSPDMLLITEPDKIIALAGVMGGENTEVTEKTASVLLESATFDKHSIRRTAKALKLQSEA
CCCCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SARFEKGLSFELAPVALKRATQLILEIAGGQAASGLMDVMPVKKDRNSVVLSLSKVNRVL
HHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCHHCCHHHHHCCCCCCCCEEEEHHHHHHHH
GLEGEKFDSCKIAKRLGFAWMPEYVPGMEEFGYGSVDDKMRFFPGYWRMDIESDIDMIEE
CCCCCCCCHHHHHHHCCCCCCHHHCCCHHHCCCCCCCCCHHHCCCEEEEECHHHHHHHHH
VARIAGYDTIPCLPLDKAIPKIETPPLPGIKRFLRQILSGYGFQELISYSFTSREMLSRV
HHHHCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHH
FSGAEPECLAISNPMSSEQEVMRTSLRPALYASLAANRRFEKNGLRLYELGRIYLPKENN
HCCCCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEECEEEECCCCC
KQDEPEMLCALIAGSASEAWWQRNTAGFDFFDAKGIVESLVSRLGIAADFAVSDEPGLTP
CCCCHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCC
GYQAGILVGDMPVGVLGQLSPQTADKFGITEPVYMFEINLSKLITRATVRRKFTQINRFP
CCCCCEEEECCCCCHHCCCCCCCHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCC
SVERDLALVLDRSITNRQVTDIISEFDLVKNVELFDMYQGKQVAEDKKSLAYHLLFQSDT
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHEEEEEEECCC
HTLKDADVDSVMNQILKRLNTETGAVLRS
CCCCCCCHHHHHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure
MKIPLKWLKEYLPTDMSPAELAERMTMAGTEVTVLNSRKDKWPNVYVGQIMEVNRHPNAD
CCCCHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEHHEEECCCCCCC
RLVLVKVDWGQGQETVVTGAPNCKAGDKVVFARTGAVLIDGHNGKEMVLKPAVLRGVESC
EEEEEEEECCCCCCEEEECCCCCCCCCEEEEEECCEEEEECCCCCEEEECHHHHHHHHHH
GMVCSERELGLSDEHEGILILPADAPVGMLASEYLGEIILDLELTPNRGDLMCVTGVARE
CCEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHEEEEEEECCCCCCEEEHHHHHHH
LGALIDRLPSISTPDFKATGKDIKDKINIEIKNTKLCTRYTASLIEGIKIGESPDWLKER
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHH
LIACGMRPINNVVDATNYVMLEFGQPLHSFDYDQIKSKHIIVRPAAEGEVLTTLDGVERK
HHHCCCCHHHHHHCCCCEEEEECCCCHHCCCHHHHCCCEEEEEECCCCCEEEHHHHHHHH
LSPDMLLITEPDKIIALAGVMGGENTEVTEKTASVLLESATFDKHSIRRTAKALKLQSEA
CCCCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SARFEKGLSFELAPVALKRATQLILEIAGGQAASGLMDVMPVKKDRNSVVLSLSKVNRVL
HHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCHHCCHHHHHCCCCCCCCEEEEHHHHHHHH
GLEGEKFDSCKIAKRLGFAWMPEYVPGMEEFGYGSVDDKMRFFPGYWRMDIESDIDMIEE
CCCCCCCCHHHHHHHCCCCCCHHHCCCHHHCCCCCCCCCHHHCCCEEEEECHHHHHHHHH
VARIAGYDTIPCLPLDKAIPKIETPPLPGIKRFLRQILSGYGFQELISYSFTSREMLSRV
HHHHCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHH
FSGAEPECLAISNPMSSEQEVMRTSLRPALYASLAANRRFEKNGLRLYELGRIYLPKENN
HCCCCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEECEEEECCCCC
KQDEPEMLCALIAGSASEAWWQRNTAGFDFFDAKGIVESLVSRLGIAADFAVSDEPGLTP
CCCCHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCC
GYQAGILVGDMPVGVLGQLSPQTADKFGITEPVYMFEINLSKLITRATVRRKFTQINRFP
CCCCCEEEECCCCCHHCCCCCCCHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCC
SVERDLALVLDRSITNRQVTDIISEFDLVKNVELFDMYQGKQVAEDKKSLAYHLLFQSDT
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHEEEEEEECCC
HTLKDADVDSVMNQILKRLNTETGAVLRS
CCCCCCCHHHHHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA