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The map label for this gene is ppa [H]

Identifier: 57234858

GI number: 57234858

Start: 349435

End: 350070

Strand: Direct

Name: ppa [H]

Synonym: DET0367

Alternate gene names: 57234858

Gene position: 349435-350070 (Clockwise)

Preceding gene: 57234859

Following gene: 57234828

Centisome position: 23.78

GC content: 43.24

Gene sequence:

>636_bases
ATGTTAAGCGATAGTTCAAAGCAGATTAAAAAAGAAGTTGAAGCCATCAATTCAGATTTTAAGACAATAGTGGGTTGCGG
TGAGTCAAAATGCCCCAAACTTAAAAGACTGAAACTGGCAAGTACCCCGGATATTATCCTTAAGGTTATGATAGAAATAC
CTAAGGGTAGCCAAAATAAATACGAATATGATAAAGAACGCAAGGTAATCAAGTTTGACCGTATGCTTTTCTCGGCCGTT
CATTATCCCAGTGACTACGGTTTTATTGAGGATACTCTGGCCGAAGACGGTGACCCGCTTGATGCTTTGGTTTTGGTTTG
GGAGCCCACCTTCCCCGGCTGTCTGATAGAGACCAAGCCGGTAGGTCTTTTCAAAATGTACGATGAAAAAGGCCCGGATG
CCAAGCTGCTGTGCGTACCCATTGGTGACCCCCACTTTAATTTTATCCGTGACCTTTCGGACGTGCCTCCCCACCTGCTT
AAAGAAATATTCCATTTCTTTAACATCTATAAAGAACTGGAAGCCAAGAAAACCGGTGTTGAAGGCTGGGAAGACCGTGA
GTCAGCCATTAAGACTTACTGGGAATCTCACCAGAGATATCTGGATTCACTTAAAAACAAGCCGGAACAGAAATAA

Upstream 100 bases:

>100_bases
TTCCTGAGTGTATTTATCCGGTTATTGCAAAAGGGGCTTTTGGGTAGAAGCCCCTTTTGGTTTTTAAGCCCGAATGAGGT
ATTATAAATGCGGAGGAAAA

Downstream 100 bases:

>100_bases
AAAATCAGGGGGGCTATTAGCCCCCCTGATTTTTTACCTTTAGACAGCTCTTGGGCAAAACAGGCAGTTATAAATCACTC
TGGCTCTTGATGCAGGTGAT

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MLSDSSKQIKKEVEAINSDFKTIVGCGESKCPKLKRLKLASTPDIILKVMIEIPKGSQNKYEYDKERKVIKFDRMLFSAV
HYPSDYGFIEDTLAEDGDPLDALVLVWEPTFPGCLIETKPVGLFKMYDEKGPDAKLLCVPIGDPHFNFIRDLSDVPPHLL
KEIFHFFNIYKELEAKKTGVEGWEDRESAIKTYWESHQRYLDSLKNKPEQK

Sequences:

>Translated_211_residues
MLSDSSKQIKKEVEAINSDFKTIVGCGESKCPKLKRLKLASTPDIILKVMIEIPKGSQNKYEYDKERKVIKFDRMLFSAV
HYPSDYGFIEDTLAEDGDPLDALVLVWEPTFPGCLIETKPVGLFKMYDEKGPDAKLLCVPIGDPHFNFIRDLSDVPPHLL
KEIFHFFNIYKELEAKKTGVEGWEDRESAIKTYWESHQRYLDSLKNKPEQK
>Mature_211_residues
MLSDSSKQIKKEVEAINSDFKTIVGCGESKCPKLKRLKLASTPDIILKVMIEIPKGSQNKYEYDKERKVIKFDRMLFSAV
HYPSDYGFIEDTLAEDGDPLDALVLVWEPTFPGCLIETKPVGLFKMYDEKGPDAKLLCVPIGDPHFNFIRDLSDVPPHLL
KEIFHFFNIYKELEAKKTGVEGWEDRESAIKTYWESHQRYLDSLKNKPEQK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=155, Percent_Identity=44.5161290322581, Blast_Score=120, Evalue=5e-29,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 24333; Mature: 24333

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDSSKQIKKEVEAINSDFKTIVGCGESKCPKLKRLKLASTPDIILKVMIEIPKGSQNK
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCCHHHHHHHHHHCCCCCCCC
YEYDKERKVIKFDRMLFSAVHYPSDYGFIEDTLAEDGDPLDALVLVWEPTFPGCLIETKP
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCEEECCC
VGLFKMYDEKGPDAKLLCVPIGDPHFNFIRDLSDVPPHLLKEIFHFFNIYKELEAKKTGV
CCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
EGWEDRESAIKTYWESHQRYLDSLKNKPEQK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLSDSSKQIKKEVEAINSDFKTIVGCGESKCPKLKRLKLASTPDIILKVMIEIPKGSQNK
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCCHHHHHHHHHHCCCCCCCC
YEYDKERKVIKFDRMLFSAVHYPSDYGFIEDTLAEDGDPLDALVLVWEPTFPGCLIETKP
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEEEEEECCCCCCCEEECCC
VGLFKMYDEKGPDAKLLCVPIGDPHFNFIRDLSDVPPHLLKEIFHFFNIYKELEAKKTGV
CCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
EGWEDRESAIKTYWESHQRYLDSLKNKPEQK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]