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The map label for this gene is murI

Identifier: 38234423

GI number: 38234423

Start: 1897092

End: 1897889

Strand: Reverse

Name: murI

Synonym: DIP1853

Alternate gene names: 38234423

Gene position: 1897889-1897092 (Counterclockwise)

Preceding gene: 38234424

Following gene: 38234422

Centisome position: 76.26

GC content: 56.14

Gene sequence:

>798_bases
GTGAATAACGCACCGATTGGGATTTTCGATTCTGGTGTCGGCGGGCTGACCGTTGCGCGAGTGATTATGGAGCAGCTGCC
CAACGAGTCGGTGATTTATATCGGAGATACCGCTAACAGTCCGTATGGGCCAAAGCCTATCGCCCAAGTTCGGGAGTTGT
CGCTGGCTATCGGCGAGGAATTAGTGCGTCGTGGCTGCAAGATGATCGTGATTGCGTGCAATACGGCAACGTCGGCGGCA
TTGCGGGACCTTCGGGAGCGTTTCGACGTCCCCGTCTTAGGCGTGATTCTTCCCGCAGTGCGCAGGGCTGTCTCAACAAC
CCGCAACGGAAAAATCGGTGTGATTGGTACGGAAGGCACCATTAAGTCGGGGGCGTATCAAGAACTATTTGCGGCGAGCC
CCTCGGTTGAGGTGCATGCACAGGCGTGCCCAAGTTTTGTCAGCTTTGTAGAACGTGGCATAACGTCGGGCCGGCAGATC
TTGGGGGTTGCGCAAGGATATGTGGAACCTCTGCAAGCCGCAGGCGTGGATACTTTGGTGCTCGGGTGCACTCATTACCC
GTTGCTGACGGGTGTGATTCAGCTGGCGATGGGCGATCGCGTCACGTTGGTGTCGTCGGCAGAAGAAACCGCGAAGGACG
TTTTTAAAACGTTGAGCATGACAGACATGCTGGCCAGCGAGGATTCCACACCAGTTCGGACATTTGAATCGACAGGGGAT
CCGGTGCTGTTCGCACAGTTGGCGGAGCGGTTCTTGGGGCCTCATGTGACGAACGTGGAAAAATTCGCGGGTATGTAA

Upstream 100 bases:

>100_bases
GGGTGTCGTGGCAGGCGCACCTGTTTGGGGCTGTTGGCGGGGTAGTGGCGGGGGCTGCTATTTCGTCGGATGATCCGAAA
CCGCGTAGGAAGGAATTGCA

Downstream 100 bases:

>100_bases
TGTGCGTTCCTTGTGTTCACTTTTTACATCAAAACGTGGCAATGTTAGCAGCATGAAGCTGACCATTCTCGGAAGTTCTG
GAAGCGTAGGTGCGCCAGAC

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MNNAPIGIFDSGVGGLTVARVIMEQLPNESVIYIGDTANSPYGPKPIAQVRELSLAIGEELVRRGCKMIVIACNTATSAA
LRDLRERFDVPVLGVILPAVRRAVSTTRNGKIGVIGTEGTIKSGAYQELFAASPSVEVHAQACPSFVSFVERGITSGRQI
LGVAQGYVEPLQAAGVDTLVLGCTHYPLLTGVIQLAMGDRVTLVSSAEETAKDVFKTLSMTDMLASEDSTPVRTFESTGD
PVLFAQLAERFLGPHVTNVEKFAGM

Sequences:

>Translated_265_residues
MNNAPIGIFDSGVGGLTVARVIMEQLPNESVIYIGDTANSPYGPKPIAQVRELSLAIGEELVRRGCKMIVIACNTATSAA
LRDLRERFDVPVLGVILPAVRRAVSTTRNGKIGVIGTEGTIKSGAYQELFAASPSVEVHAQACPSFVSFVERGITSGRQI
LGVAQGYVEPLQAAGVDTLVLGCTHYPLLTGVIQLAMGDRVTLVSSAEETAKDVFKTLSMTDMLASEDSTPVRTFESTGD
PVLFAQLAERFLGPHVTNVEKFAGM
>Mature_265_residues
MNNAPIGIFDSGVGGLTVARVIMEQLPNESVIYIGDTANSPYGPKPIAQVRELSLAIGEELVRRGCKMIVIACNTATSAA
LRDLRERFDVPVLGVILPAVRRAVSTTRNGKIGVIGTEGTIKSGAYQELFAASPSVEVHAQACPSFVSFVERGITSGRQI
LGVAQGYVEPLQAAGVDTLVLGCTHYPLLTGVIQLAMGDRVTLVSSAEETAKDVFKTLSMTDMLASEDSTPVRTFESTGD
PVLFAQLAERFLGPHVTNVEKFAGM

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=186, Percent_Identity=37.6344086021505, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_CORDI (Q6NFN4)

Other databases:

- EMBL:   BX248359
- RefSeq:   NP_940190.1
- HSSP:   P94556
- ProteinModelPortal:   Q6NFN4
- SMR:   Q6NFN4
- GeneID:   2649228
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1853
- NMPDR:   fig|257309.1.peg.1781
- HOGENOM:   HBG645102
- OMA:   CGHIPYG
- PhylomeDB:   Q6NFN4
- ProtClustDB:   PRK00865
- BioCyc:   CDIP257309:DIP1853-MONOMER
- BRENDA:   5.1.1.3
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 28098; Mature: 28098

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNAPIGIFDSGVGGLTVARVIMEQLPNESVIYIGDTANSPYGPKPIAQVRELSLAIGEE
CCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
LVRRGCKMIVIACNTATSAALRDLRERFDVPVLGVILPAVRRAVSTTRNGKIGVIGTEGT
HHHCCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCC
IKSGAYQELFAASPSVEVHAQACPSFVSFVERGITSGRQILGVAQGYVEPLQAAGVDTLV
CCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHEE
LGCTHYPLLTGVIQLAMGDRVTLVSSAEETAKDVFKTLSMTDMLASEDSTPVRTFESTGD
ECCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCC
PVLFAQLAERFLGPHVTNVEKFAGM
CCHHHHHHHHHCCCCCCCHHHHHCC
>Mature Secondary Structure
MNNAPIGIFDSGVGGLTVARVIMEQLPNESVIYIGDTANSPYGPKPIAQVRELSLAIGEE
CCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
LVRRGCKMIVIACNTATSAALRDLRERFDVPVLGVILPAVRRAVSTTRNGKIGVIGTEGT
HHHCCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCC
IKSGAYQELFAASPSVEVHAQACPSFVSFVERGITSGRQILGVAQGYVEPLQAAGVDTLV
CCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHEE
LGCTHYPLLTGVIQLAMGDRVTLVSSAEETAKDVFKTLSMTDMLASEDSTPVRTFESTGD
ECCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCC
PVLFAQLAERFLGPHVTNVEKFAGM
CCHHHHHHHHHCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910