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The map label for this gene is 38234424

Identifier: 38234424

GI number: 38234424

Start: 1897886

End: 1898458

Strand: Reverse

Name: 38234424

Synonym: DIP1854

Alternate gene names: NA

Gene position: 1898458-1897886 (Counterclockwise)

Preceding gene: 38234425

Following gene: 38234423

Centisome position: 76.29

GC content: 56.37

Gene sequence:

>573_bases
ATGAAAACAGGCGTGCTTGCAGCCCTTGGCTACATTATAGCAATCTGGGCCGTCCACATTATCAATATCGTGTTCTTTGG
CGGCTACCTAGCGCAGATCCTCGGCATCCATCCGTTAGATATCCCCAGCGTGTGGCATATTTTCACCTCACCATTCATCC
ATGGCAGTCAAGCCCACCTGATGGCCAATACTGTTCCCGGCGCGATCTTCGCGTTCTTCGTCGGTTTGTCTGGCAAGCGG
GCGTTTTGGGAGGTTGCGTTTATCGTCGCTGTGGTCGGCGGCTTAGGCACGTGGATTTTCGGCGGGATCGGTACAAGCCA
TATTGGTGCATCGGGAATGATTTATGGCTGGCTGGCGTATCTTGTGGTGCGAGGAATTTTTAATCGCAGCCTCGCTCAGG
CGGCGCTAGGCGTGGTCTTGGCGTTTATGTATGGCGGCTTGGTGTGGGGTGTGCTGCCGCTGGAGCCTGGGGTGTCGTGG
CAGGCGCACCTGTTTGGGGCTGTTGGCGGGGTAGTGGCGGGGGCTGCTATTTCGTCGGATGATCCGAAACCGCGTAGGAA
GGAATTGCAGTGA

Upstream 100 bases:

>100_bases
GCGCAGCTGCGGAAGTGGTAGCTCAAGCAATCGTGTCCGCTGTAGTCAACGCAACATCGGCATACGGGATGACAGCACTA
TCGGAAATCGAGGCGGTTGA

Downstream 100 bases:

>100_bases
ATAACGCACCGATTGGGATTTTCGATTCTGGTGTCGGCGGGCTGACCGTTGCGCGAGTGATTATGGAGCAGCTGCCCAAC
GAGTCGGTGATTTATATCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKTGVLAALGYIIAIWAVHIINIVFFGGYLAQILGIHPLDIPSVWHIFTSPFIHGSQAHLMANTVPGAIFAFFVGLSGKR
AFWEVAFIVAVVGGLGTWIFGGIGTSHIGASGMIYGWLAYLVVRGIFNRSLAQAALGVVLAFMYGGLVWGVLPLEPGVSW
QAHLFGAVGGVVAGAAISSDDPKPRRKELQ

Sequences:

>Translated_190_residues
MKTGVLAALGYIIAIWAVHIINIVFFGGYLAQILGIHPLDIPSVWHIFTSPFIHGSQAHLMANTVPGAIFAFFVGLSGKR
AFWEVAFIVAVVGGLGTWIFGGIGTSHIGASGMIYGWLAYLVVRGIFNRSLAQAALGVVLAFMYGGLVWGVLPLEPGVSW
QAHLFGAVGGVVAGAAISSDDPKPRRKELQ
>Mature_190_residues
MKTGVLAALGYIIAIWAVHIINIVFFGGYLAQILGIHPLDIPSVWHIFTSPFIHGSQAHLMANTVPGAIFAFFVGLSGKR
AFWEVAFIVAVVGGLGTWIFGGIGTSHIGASGMIYGWLAYLVVRGIFNRSLAQAALGVVLAFMYGGLVWGVLPLEPGVSW
QAHLFGAVGGVVAGAAISSDDPKPRRKELQ

Specific function: Unknown

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1171 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: NA

Molecular weight: Translated: 20100; Mature: 20100

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS00485 A_DEAMINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTGVLAALGYIIAIWAVHIINIVFFGGYLAQILGIHPLDIPSVWHIFTSPFIHGSQAHL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHH
MANTVPGAIFAFFVGLSGKRAFWEVAFIVAVVGGLGTWIFGGIGTSHIGASGMIYGWLAY
HHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHH
LVVRGIFNRSLAQAALGVVLAFMYGGLVWGVLPLEPGVSWQAHLFGAVGGVVAGAAISSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCC
DPKPRRKELQ
CCCCHHCCCC
>Mature Secondary Structure
MKTGVLAALGYIIAIWAVHIINIVFFGGYLAQILGIHPLDIPSVWHIFTSPFIHGSQAHL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHH
MANTVPGAIFAFFVGLSGKRAFWEVAFIVAVVGGLGTWIFGGIGTSHIGASGMIYGWLAY
HHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHH
LVVRGIFNRSLAQAALGVVLAFMYGGLVWGVLPLEPGVSWQAHLFGAVGGVVAGAAISSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCC
DPKPRRKELQ
CCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]