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The map label for this gene is yebQ [C]

Identifier: 38233676

GI number: 38233676

Start: 1064159

End: 1065574

Strand: Direct

Name: yebQ [C]

Synonym: DIP1082

Alternate gene names: 38233676

Gene position: 1064159-1065574 (Clockwise)

Preceding gene: 38233674

Following gene: 38233678

Centisome position: 42.76

GC content: 49.79

Gene sequence:

>1416_bases
ATGTTGAGCACAGCAACTAAATCTGACACTCAGTATCCCACCATGCCGTTGCCGGAAAAAGAGGCATGGCCTGCACTAAT
TGCATTGTGTATTGGGTTTTTTATGATCCTTTTGGATCAAACCATCGTTGCCGTTGCTACTCCTGCGCTGCAAGCGGATC
TTCATGCCTCCTACAACGAGGTTATTTGGGTAACGTCGGCCTATTTGCTGACTTTTGCTGTACCTCTGCTTATCACAGGG
CGACTAGGGGATCGATTCGGTCCTAAGAATATTTACATCATTGGCATGGTGATCTTTACGCTTAGTTCTCTTGCCTGTGG
TTTTGCGCCAAATATGATGACGTTGATTATCGCCCGTGCGGTTCAGGGTATCGGTGCATCTATGCTGACGCCACAGACTA
TGAGCGTGATCAACCGTGTGTTTGCTCGTGAACGTCGTGGTGCGGCGCTAGGAATCTGGGGCAGTGTTGCCGGAATTGCT
AGCCTTGCTGGCCCGATCTTAGGTGGGTTTATTACTGCTTGGGTCGGTTGGCAGTGGATCTTTTTCATCAACGTGCCTAT
CGGCGTTGTGTCTGTATTTGCTGTTGCCCGCTTTGTTCCGCGTTTTAAGCCAACTGAGCGCAGTATCGACGGTTTGAGCA
TGGTGCTTTCTGTCGTTTCTGTTTTTGCGTTGGTGTTTGCCTTGCAACAAGGTGAATCTGCTGGCTGGGCATGGTGGATT
TGGGTTGTCATGGTTGTTGGTATTGCGGTGGGCGTACTGTTTGCGTATCAGCAAAATCGTGCAGAAGCCAAGGGAAAAGA
TGCGCTTATGCCACTTTCGCTTTTCCGTGTACGAAACTTTTCTCTCGGAAACATTGGTATTGCTGCGATGGGCTTTACTA
TTGCTGGCACTCCGCTTCCGATCATGCTGTACCTTCAGCAGGTTCATTCGCTTACACCGCTTCAGGCCGGCTTGTTCATG
ATGCCCCAAGCATTGATTTCGGCGTTTTTCTCTCCACTCATCGGCCGCTGGTCTGATCATTATTCGACTAGCAAATTGGC
AGGTTTTGGTTTTTCTACGATGGCTATGGGGCTTGTTTTGATCGCAGCGGTCATGATTATTGATGTCAATCTGTGGTGGT
TGGTTCCGGCATTTATCGTTTATGGATTGGGCAATGCTTTTGTGTGGTCGCCAAACTCTACGTCGACCATGCGTGATTTG
CCGCTTCATCACATGGGTGTGGGATCTGGCGTATATAACACGACACGACAGATTGGTTGTGTGATTGGTTCTGCTGCGAT
CGGTGCAGTACTGCAGTGGCGCATTATGGCGGGGGATATGGGTGCTGCTTATGGGCAGTCGATTATTCTCGGCGCGGTGA
TGCTAGCGGTTGGATTTGTTTCTGCGATGTTGGCGCAAGATAAGCCCCGCCGTTAG

Upstream 100 bases:

>100_bases
CAGTTGTGGGCACTAATGTGAATTCTGAAGCTGACATGATGACAAGTCTACTATTTTTAGGTGTATTGTGTTTCCAGTCG
ATTGTGAAACTAGGAGGTAG

Downstream 100 bases:

>100_bases
TCGCTTTAAAAAGGTCTCATTATCATTCTCAATGAGAGTGTGGTAGTGGGGCTTTGTGCTATTGAGCTGCGTCGTTGATT
AAATATGCTGCGGCAGCTGT

Product: major facilitator family transmembrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MLSTATKSDTQYPTMPLPEKEAWPALIALCIGFFMILLDQTIVAVATPALQADLHASYNEVIWVTSAYLLTFAVPLLITG
RLGDRFGPKNIYIIGMVIFTLSSLACGFAPNMMTLIIARAVQGIGASMLTPQTMSVINRVFARERRGAALGIWGSVAGIA
SLAGPILGGFITAWVGWQWIFFINVPIGVVSVFAVARFVPRFKPTERSIDGLSMVLSVVSVFALVFALQQGESAGWAWWI
WVVMVVGIAVGVLFAYQQNRAEAKGKDALMPLSLFRVRNFSLGNIGIAAMGFTIAGTPLPIMLYLQQVHSLTPLQAGLFM
MPQALISAFFSPLIGRWSDHYSTSKLAGFGFSTMAMGLVLIAAVMIIDVNLWWLVPAFIVYGLGNAFVWSPNSTSTMRDL
PLHHMGVGSGVYNTTRQIGCVIGSAAIGAVLQWRIMAGDMGAAYGQSIILGAVMLAVGFVSAMLAQDKPRR

Sequences:

>Translated_471_residues
MLSTATKSDTQYPTMPLPEKEAWPALIALCIGFFMILLDQTIVAVATPALQADLHASYNEVIWVTSAYLLTFAVPLLITG
RLGDRFGPKNIYIIGMVIFTLSSLACGFAPNMMTLIIARAVQGIGASMLTPQTMSVINRVFARERRGAALGIWGSVAGIA
SLAGPILGGFITAWVGWQWIFFINVPIGVVSVFAVARFVPRFKPTERSIDGLSMVLSVVSVFALVFALQQGESAGWAWWI
WVVMVVGIAVGVLFAYQQNRAEAKGKDALMPLSLFRVRNFSLGNIGIAAMGFTIAGTPLPIMLYLQQVHSLTPLQAGLFM
MPQALISAFFSPLIGRWSDHYSTSKLAGFGFSTMAMGLVLIAAVMIIDVNLWWLVPAFIVYGLGNAFVWSPNSTSTMRDL
PLHHMGVGSGVYNTTRQIGCVIGSAAIGAVLQWRIMAGDMGAAYGQSIILGAVMLAVGFVSAMLAQDKPRR
>Mature_471_residues
MLSTATKSDTQYPTMPLPEKEAWPALIALCIGFFMILLDQTIVAVATPALQADLHASYNEVIWVTSAYLLTFAVPLLITG
RLGDRFGPKNIYIIGMVIFTLSSLACGFAPNMMTLIIARAVQGIGASMLTPQTMSVINRVFARERRGAALGIWGSVAGIA
SLAGPILGGFITAWVGWQWIFFINVPIGVVSVFAVARFVPRFKPTERSIDGLSMVLSVVSVFALVFALQQGESAGWAWWI
WVVMVVGIAVGVLFAYQQNRAEAKGKDALMPLSLFRVRNFSLGNIGIAAMGFTIAGTPLPIMLYLQQVHSLTPLQAGLFM
MPQALISAFFSPLIGRWSDHYSTSKLAGFGFSTMAMGLVLIAAVMIIDVNLWWLVPAFIVYGLGNAFVWSPNSTSTMRDL
PLHHMGVGSGVYNTTRQIGCVIGSAAIGAVLQWRIMAGDMGAAYGQSIILGAVMLAVGFVSAMLAQDKPRR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=435, Percent_Identity=31.264367816092, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1789042, Length=408, Percent_Identity=30.3921568627451, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1790195, Length=419, Percent_Identity=28.6396181384248, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1788710, Length=421, Percent_Identity=28.7410926365796, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1788392, Length=424, Percent_Identity=30.188679245283, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI48994889, Length=165, Percent_Identity=29.0909090909091, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790146, Length=173, Percent_Identity=26.5895953757225, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87082320, Length=175, Percent_Identity=26.2857142857143, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI87082231, Length=222, Percent_Identity=23.8738738738739, Blast_Score=62, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324954, Length=403, Percent_Identity=27.7915632754342, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319770, Length=338, Percent_Identity=25.4437869822485, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6321663, Length=137, Percent_Identity=32.8467153284672, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322958, Length=189, Percent_Identity=32.2751322751323, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323735, Length=396, Percent_Identity=25.2525252525253, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325455, Length=169, Percent_Identity=27.810650887574, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323520, Length=234, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50728; Mature: 50728

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS00061 ADH_SHORT ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTATKSDTQYPTMPLPEKEAWPALIALCIGFFMILLDQTIVAVATPALQADLHASYNE
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCC
VIWVTSAYLLTFAVPLLITGRLGDRFGPKNIYIIGMVIFTLSSLACGFAPNMMTLIIARA
EEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHHH
VQGIGASMLTPQTMSVINRVFARERRGAALGIWGSVAGIASLAGPILGGFITAWVGWQWI
HHHCCCHHCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
FFINVPIGVVSVFAVARFVPRFKPTERSIDGLSMVLSVVSVFALVFALQQGESAGWAWWI
EEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
WVVMVVGIAVGVLFAYQQNRAEAKGKDALMPLSLFRVRNFSLGNIGIAAMGFTIAGTPLP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCEECCCCHH
IMLYLQQVHSLTPLQAGLFMMPQALISAFFSPLIGRWSDHYSTSKLAGFGFSTMAMGLVL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHH
IAAVMIIDVNLWWLVPAFIVYGLGNAFVWSPNSTSTMRDLPLHHMGVGSGVYNTTRQIGC
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHCCCHHCCCCCCHHHHHHHHHH
VIGSAAIGAVLQWRIMAGDMGAAYGQSIILGAVMLAVGFVSAMLAQDKPRR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLSTATKSDTQYPTMPLPEKEAWPALIALCIGFFMILLDQTIVAVATPALQADLHASYNE
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCC
VIWVTSAYLLTFAVPLLITGRLGDRFGPKNIYIIGMVIFTLSSLACGFAPNMMTLIIARA
EEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHHH
VQGIGASMLTPQTMSVINRVFARERRGAALGIWGSVAGIASLAGPILGGFITAWVGWQWI
HHHCCCHHCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
FFINVPIGVVSVFAVARFVPRFKPTERSIDGLSMVLSVVSVFALVFALQQGESAGWAWWI
EEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
WVVMVVGIAVGVLFAYQQNRAEAKGKDALMPLSLFRVRNFSLGNIGIAAMGFTIAGTPLP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCEECCCCHH
IMLYLQQVHSLTPLQAGLFMMPQALISAFFSPLIGRWSDHYSTSKLAGFGFSTMAMGLVL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHH
IAAVMIIDVNLWWLVPAFIVYGLGNAFVWSPNSTSTMRDLPLHHMGVGSGVYNTTRQIGC
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHCCCHHCCCCCCHHHHHHHHHH
VIGSAAIGAVLQWRIMAGDMGAAYGQSIILGAVMLAVGFVSAMLAQDKPRR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]