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The map label for this gene is fecD [C]

Identifier: 38233678

GI number: 38233678

Start: 1066370

End: 1067410

Strand: Direct

Name: fecD [C]

Synonym: DIP1084

Alternate gene names: 38233678

Gene position: 1066370-1067410 (Clockwise)

Preceding gene: 38233676

Following gene: 38233679

Centisome position: 42.85

GC content: 51.78

Gene sequence:

>1041_bases
GTGATCAGACGACTTACCACGCCCGTACTATTTATTGCACTTCTTATTGTGGCGGCCGTTAGTTTTGTCATCTCCTTATC
TTTTGGTTCTGTCGACTACCCACAGGAGCAAGTATGGGCGGTAGTAAAAGCTCATCTTGCCGGAGACGTCTACCCAGATC
AGTCGATTGATGCAGTGGTATGGGAATTGCGAGCACCTCGTGGCGTTTTAGCTCTTATTGTCGGTGCAGGTTTGGCGCTC
GCCGGTGTTGCAATGCAGACCTTGGTGCGTAACCCATTGGCAGATCCTTATCTCCTGGGCATTAGCTCTGGTGCGAGTGT
GGGTGCGACCGCAGTGCTCGTTTTTGGTTTGCTAGGAAATTTTGGACTTTACGCGCTTTCTGGTGGAGCTCTAGTGGGTG
CAATTATCGCTACGTTTGCGGTGTATGCAGTTACCCTTGCTCAAGGTGGGTTGACACCGTTGCGATTAATTTTGTCAGGT
GTTGTGCTTTCGTCAGCTTTTTCTGCGCTCGCTAGCTTTCTGGTTTTTAAAGGTCCAGATGCTCGCGCTGCTCAAGGCGT
GATGTTTTGGATGCTTGGTTCGGTTGCTGGCGCGCAATGGGGAAAACTTGCTATTCCTGCCGTTGTAGTAGCACTGGCTT
TTGCTGGTTTGCTGTTTATTAATCGTCAGATGGATGCGCTGGCTGCTGGTCCTGACACCGCAGCAGCTTTAGGAGTCAAC
GTTCCAGCCTTGCGTCAGGGGCTATTTTTCCTCCAAGCGATGCTCGTTGGCGCCATGGTTGCGGTAGCTGGTGGAATTGG
ATTCGTGGGACTTGTGATCCCTCACTTGGCGCGCATGATGGTGGGCTCTCTGCATCGTCGGTTGTTGCCCATCGCTGCTG
CTTTTGGTGCAGTGTTTATGGTGTGGGTTGATGTGTTGGCTCGGGTTGCAGCACCTCCTCAAGAAATTCCGCTCGGTGTT
GTTACGGGTGTTATCGGAGCCCCGTTATTCCTAATTTTGATGGGACGTAAGAGCTATCGCTTTGGGGGACAGGAGTCATG
A

Upstream 100 bases:

>100_bases
GCGTAGAGCACCCCAGTCCGAAGACCGGCCTAATCAGAAACATGTGCTGCTGTCCTCGCGTTCTAGGTAAGCAGACCGAT
ATGTAGTTGAAGTTGGTCAT

Downstream 100 bases:

>100_bases
TGCATTGCCAAGCACAGGGTATTGCTTGTGGTTTTGATACCAAGACAACGATTTTGAAAGACATTTCCTTTTCTGTTGAT
CAGGGCACGATGACTGCGAT

Product: iron ABC transporter membrane protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MIRRLTTPVLFIALLIVAAVSFVISLSFGSVDYPQEQVWAVVKAHLAGDVYPDQSIDAVVWELRAPRGVLALIVGAGLAL
AGVAMQTLVRNPLADPYLLGISSGASVGATAVLVFGLLGNFGLYALSGGALVGAIIATFAVYAVTLAQGGLTPLRLILSG
VVLSSAFSALASFLVFKGPDARAAQGVMFWMLGSVAGAQWGKLAIPAVVVALAFAGLLFINRQMDALAAGPDTAAALGVN
VPALRQGLFFLQAMLVGAMVAVAGGIGFVGLVIPHLARMMVGSLHRRLLPIAAAFGAVFMVWVDVLARVAAPPQEIPLGV
VTGVIGAPLFLILMGRKSYRFGGQES

Sequences:

>Translated_346_residues
MIRRLTTPVLFIALLIVAAVSFVISLSFGSVDYPQEQVWAVVKAHLAGDVYPDQSIDAVVWELRAPRGVLALIVGAGLAL
AGVAMQTLVRNPLADPYLLGISSGASVGATAVLVFGLLGNFGLYALSGGALVGAIIATFAVYAVTLAQGGLTPLRLILSG
VVLSSAFSALASFLVFKGPDARAAQGVMFWMLGSVAGAQWGKLAIPAVVVALAFAGLLFINRQMDALAAGPDTAAALGVN
VPALRQGLFFLQAMLVGAMVAVAGGIGFVGLVIPHLARMMVGSLHRRLLPIAAAFGAVFMVWVDVLARVAAPPQEIPLGV
VTGVIGAPLFLILMGRKSYRFGGQES
>Mature_346_residues
MIRRLTTPVLFIALLIVAAVSFVISLSFGSVDYPQEQVWAVVKAHLAGDVYPDQSIDAVVWELRAPRGVLALIVGAGLAL
AGVAMQTLVRNPLADPYLLGISSGASVGATAVLVFGLLGNFGLYALSGGALVGAIIATFAVYAVTLAQGGLTPLRLILSG
VVLSSAFSALASFLVFKGPDARAAQGVMFWMLGSVAGAQWGKLAIPAVVVALAFAGLLFINRQMDALAAGPDTAAALGVN
VPALRQGLFFLQAMLVGAMVAVAGGIGFVGLVIPHLARMMVGSLHRRLLPIAAAFGAVFMVWVDVLARVAAPPQEIPLGV
VTGVIGAPLFLILMGRKSYRFGGQES

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=280, Percent_Identity=38.2142857142857, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788004, Length=291, Percent_Identity=37.8006872852234, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1790741, Length=285, Percent_Identity=37.5438596491228, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786805, Length=290, Percent_Identity=37.9310344827586, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786347, Length=319, Percent_Identity=34.4827586206897, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1786804, Length=338, Percent_Identity=31.3609467455621, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35599; Mature: 35599

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRLTTPVLFIALLIVAAVSFVISLSFGSVDYPQEQVWAVVKAHLAGDVYPDQSIDAVV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
WELRAPRGVLALIVGAGLALAGVAMQTLVRNPLADPYLLGISSGASVGATAVLVFGLLGN
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHC
FGLYALSGGALVGAIIATFAVYAVTLAQGGLTPLRLILSGVVLSSAFSALASFLVFKGPD
CHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ARAAQGVMFWMLGSVAGAQWGKLAIPAVVVALAFAGLLFINRQMDALAAGPDTAAALGVN
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
VPALRQGLFFLQAMLVGAMVAVAGGIGFVGLVIPHLARMMVGSLHRRLLPIAAAFGAVFM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWVDVLARVAAPPQEIPLGVVTGVIGAPLFLILMGRKSYRFGGQES
HHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIRRLTTPVLFIALLIVAAVSFVISLSFGSVDYPQEQVWAVVKAHLAGDVYPDQSIDAVV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
WELRAPRGVLALIVGAGLALAGVAMQTLVRNPLADPYLLGISSGASVGATAVLVFGLLGN
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHC
FGLYALSGGALVGAIIATFAVYAVTLAQGGLTPLRLILSGVVLSSAFSALASFLVFKGPD
CHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ARAAQGVMFWMLGSVAGAQWGKLAIPAVVVALAFAGLLFINRQMDALAAGPDTAAALGVN
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
VPALRQGLFFLQAMLVGAMVAVAGGIGFVGLVIPHLARMMVGSLHRRLLPIAAAFGAVFM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWVDVLARVAAPPQEIPLGVVTGVIGAPLFLILMGRKSYRFGGQES
HHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]