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The map label for this gene is aroA [H]

Identifier: 38233313

GI number: 38233313

Start: 681984

End: 683279

Strand: Reverse

Name: aroA [H]

Synonym: DIP0706

Alternate gene names: 38233313

Gene position: 683279-681984 (Counterclockwise)

Preceding gene: 38233315

Following gene: 38233312

Centisome position: 27.46

GC content: 58.18

Gene sequence:

>1296_bases
ATGGCACAATTGTGGGACGCACCAACCCCAACCAATGCGGTACATGCAACTGTACGGGTTCCGGGGTCTAAGTCGATGAC
CAACCGCGCGCTTATCTTGTCCGCGATCGCTCATCGCCCAGCACAGATAAACGGGGCGCTACGTTCACGCGACACCGACT
TAATGATCCGCGCGCTCACCGCCCTAGGTGCTAGCGTGCGTTTCGACGACCCCAATCACGGTGCGGCATCCACATCACTG
TACGTCACCCCCGCGCCTTTCCACAGCGCCACCATCGACTGCGGCCTGGCCGGAACAGTCATGCGTTTTGTTCCGCCCAT
TGCTGCATTAGCGCATGGCAGTGTGTTCTTTGACGGAGATGTGCAAGCACGTACTCGCCCCATGGGAGAAATCCTCGATG
CCCTCCGCACGCTGGGGGTAACTGTTACCGGCACCCAGCTCCCCTTCCATGTGGAAGCCTCAGGACAGCCCGCCGGCGGT
GTAGTCGACATCGACGCGTCTGGATCCTCCCAGTTCGTCTCGGGACTTTTGCTTGCCGGCGCACGCTATCGCACCGGACT
GACCGTGCGGCATATCGGCGGCAAGTTGCCAAGCCTGCCGCATATTGAGATGACTGTTGATATGCTGCGTCTTGCTGGTG
TGCAGGTGGATGATTCCGTAGAAAACGAATGGCGAGTAGAACCAAGTGACGTAGAAGCTCGAACTTGGAACATCGAACCG
GATCTCTCCAATGCCGCACCCTTTCTCGCAGCGGCAGCCGTGACCGGAGGGACGGTCACCATTCCGGATTGGCCACAGCG
CACGACCCAAGCCGGCAACGTGATCCGCGATATTTTAAGTCGTATGGGCTGCACCGTTGAGATGATTTCTCGAGGTTCGA
GTTTTGATCTGCGCGTAACTGGCCCAGCGCGCGGTCAGCTGAAGGGAATTTCTCTCGACATGTCCGATATTGGTGAGCTC
ACCCCCACTGTTGCAGCTCTGGCGGCTCTTGCCACAACACCTTCAAAGTTGGTGGGAATCGCTCATCTGCGTGGGCATGA
GACTGATCGGCTAGCGGCGTTGACTCAAGAAATCACAGGTCTTGGTGGCTCATGTACCGAGCTTGCCGACGGCCTCCACA
TCACACCCAGTACGCTTCATGGCGGGACGTGGCATTCCTATGCGGATCACCGAATGGCTACTGCTGGTGCCATCATCGGC
CTTGTTGTTGGCGGTGTCCAAGTTGACGACATTGACACGACGTCGAAGACTCTGCCTGGTTTTGCCGATATGTGGCACAC
GATGGTGCGGGGCTAG

Upstream 100 bases:

>100_bases
GCGTGAATGCTGTGAAAAATCCGCAGCGCTGGGTGTCCCAAAAGCGACTCGTCGGTGGTAAACAAAACAAAGCGTCCGCA
CATGCCTTTATTATGGAGGA

Downstream 100 bases:

>100_bases
GTCGATGGCACGCAGAAACTCTCATCGCCAATGGGATGAATCCGACGTACGTGTACGCCCCAGCAAAGGCTCACGCCCCC
GTACGAAAGACCGCCCGAAG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MAQLWDAPTPTNAVHATVRVPGSKSMTNRALILSAIAHRPAQINGALRSRDTDLMIRALTALGASVRFDDPNHGAASTSL
YVTPAPFHSATIDCGLAGTVMRFVPPIAALAHGSVFFDGDVQARTRPMGEILDALRTLGVTVTGTQLPFHVEASGQPAGG
VVDIDASGSSQFVSGLLLAGARYRTGLTVRHIGGKLPSLPHIEMTVDMLRLAGVQVDDSVENEWRVEPSDVEARTWNIEP
DLSNAAPFLAAAAVTGGTVTIPDWPQRTTQAGNVIRDILSRMGCTVEMISRGSSFDLRVTGPARGQLKGISLDMSDIGEL
TPTVAALAALATTPSKLVGIAHLRGHETDRLAALTQEITGLGGSCTELADGLHITPSTLHGGTWHSYADHRMATAGAIIG
LVVGGVQVDDIDTTSKTLPGFADMWHTMVRG

Sequences:

>Translated_431_residues
MAQLWDAPTPTNAVHATVRVPGSKSMTNRALILSAIAHRPAQINGALRSRDTDLMIRALTALGASVRFDDPNHGAASTSL
YVTPAPFHSATIDCGLAGTVMRFVPPIAALAHGSVFFDGDVQARTRPMGEILDALRTLGVTVTGTQLPFHVEASGQPAGG
VVDIDASGSSQFVSGLLLAGARYRTGLTVRHIGGKLPSLPHIEMTVDMLRLAGVQVDDSVENEWRVEPSDVEARTWNIEP
DLSNAAPFLAAAAVTGGTVTIPDWPQRTTQAGNVIRDILSRMGCTVEMISRGSSFDLRVTGPARGQLKGISLDMSDIGEL
TPTVAALAALATTPSKLVGIAHLRGHETDRLAALTQEITGLGGSCTELADGLHITPSTLHGGTWHSYADHRMATAGAIIG
LVVGGVQVDDIDTTSKTLPGFADMWHTMVRG
>Mature_430_residues
AQLWDAPTPTNAVHATVRVPGSKSMTNRALILSAIAHRPAQINGALRSRDTDLMIRALTALGASVRFDDPNHGAASTSLY
VTPAPFHSATIDCGLAGTVMRFVPPIAALAHGSVFFDGDVQARTRPMGEILDALRTLGVTVTGTQLPFHVEASGQPAGGV
VDIDASGSSQFVSGLLLAGARYRTGLTVRHIGGKLPSLPHIEMTVDMLRLAGVQVDDSVENEWRVEPSDVEARTWNIEPD
LSNAAPFLAAAAVTGGTVTIPDWPQRTTQAGNVIRDILSRMGCTVEMISRGSSFDLRVTGPARGQLKGISLDMSDIGELT
PTVAALAALATTPSKLVGIAHLRGHETDRLAALTQEITGLGGSCTELADGLHITPSTLHGGTWHSYADHRMATAGAIIGL
VVGGVQVDDIDTTSKTLPGFADMWHTMVRG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=424, Percent_Identity=33.0188679245283, Blast_Score=173, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6320332, Length=462, Percent_Identity=28.7878787878788, Blast_Score=158, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 45229; Mature: 45098

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLWDAPTPTNAVHATVRVPGSKSMTNRALILSAIAHRPAQINGALRSRDTDLMIRALT
CCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHCCHHHCCCHHHHHHHHH
ALGASVRFDDPNHGAASTSLYVTPAPFHSATIDCGLAGTVMRFVPPIAALAHGSVFFDGD
HCCCEEEECCCCCCCCCCEEEEECCCCCCCEECCCHHHHHHHHHHHHHHHHCCCEEECCC
VQARTRPMGEILDALRTLGVTVTGTQLPFHVEASGQPAGGVVDIDASGSSQFVSGLLLAG
CCHHCCCHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHCC
ARYRTGLTVRHIGGKLPSLPHIEMTVDMLRLAGVQVDDSVENEWRVEPSDVEARTWNIEP
CHHHCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCC
DLSNAAPFLAAAAVTGGTVTIPDWPQRTTQAGNVIRDILSRMGCTVEMISRGSSFDLRVT
CCCCCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHCCEEEHHHCCCCEEEEEE
GPARGQLKGISLDMSDIGELTPTVAALAALATTPSKLVGIAHLRGHETDRLAALTQEITG
CCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCHHHHHEEHHHCCCCHHHHHHHHHHHHC
LGGSCTELADGLHITPSTLHGGTWHSYADHRMATAGAIIGLVVGGVQVDDIDTTSKTLPG
CCCCHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHCCCC
FADMWHTMVRG
HHHHHHHHHCC
>Mature Secondary Structure 
AQLWDAPTPTNAVHATVRVPGSKSMTNRALILSAIAHRPAQINGALRSRDTDLMIRALT
CCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHCCHHHCCCHHHHHHHHH
ALGASVRFDDPNHGAASTSLYVTPAPFHSATIDCGLAGTVMRFVPPIAALAHGSVFFDGD
HCCCEEEECCCCCCCCCCEEEEECCCCCCCEECCCHHHHHHHHHHHHHHHHCCCEEECCC
VQARTRPMGEILDALRTLGVTVTGTQLPFHVEASGQPAGGVVDIDASGSSQFVSGLLLAG
CCHHCCCHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHCC
ARYRTGLTVRHIGGKLPSLPHIEMTVDMLRLAGVQVDDSVENEWRVEPSDVEARTWNIEP
CHHHCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCC
DLSNAAPFLAAAAVTGGTVTIPDWPQRTTQAGNVIRDILSRMGCTVEMISRGSSFDLRVT
CCCCCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHCCEEEHHHCCCCEEEEEE
GPARGQLKGISLDMSDIGELTPTVAALAALATTPSKLVGIAHLRGHETDRLAALTQEITG
CCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCHHHHHEEHHHCCCCHHHHHHHHHHHHC
LGGSCTELADGLHITPSTLHGGTWHSYADHRMATAGAIIGLVVGGVQVDDIDTTSKTLPG
CCCCHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCHHCCCC
FADMWHTMVRG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA