| Definition | Corynebacterium diphtheriae NCTC 13129 chromosome, complete genome. |
|---|---|
| Accession | NC_002935 |
| Length | 2,488,635 |
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The map label for this gene is icd [H]
Identifier: 38233238
GI number: 38233238
Start: 600526
End: 602739
Strand: Reverse
Name: icd [H]
Synonym: DIP0631
Alternate gene names: 38233238
Gene position: 602739-600526 (Counterclockwise)
Preceding gene: 38233244
Following gene: 38233237
Centisome position: 24.22
GC content: 59.08
Gene sequence:
>2214_bases ATGGCGAAAATCATTTACACCCGCACCGACGAAGCACCGTTGCTTGCTACGTACTCCCTGAAGCCAGTCGTCGAAGCCTT CGCTTCCACCGCCGGCATCGAGGTTGAAACTCGCGATATTTCCCTCGCGGGCCGTATTCTTGCCCAGTTCCCTGACTATC TCAACGAGGATCAGAAGGTCGACGACGCACTTGCAGAGCTCGGCGAGCTGGCCAAGACCCCAGAAGCAAACATCATTAAG CTTCCTAATATTTCGGCATCCGTGCCACAGCTCAAAGCAGCCATTGCAGAGCTCAAAGCACAGGGCTTCGCACTTCCGGA GTACCCAGACTCCCCCGCCACCGATGAAGAAAAAGACGTCCGTGCGCGCTACGATGCCGTCAAGGGCTCTGCCGTCAACC CAGTACTTCGTGAGGGCAACTCCGACCGCCGCGCCCCCATCGCGGTGAAGAACTTCGCCAAGAAGAACCCCCACAAGATG GGCGTTTGGTCCGCTGACTCCAAGACCAACGTAGCCACCATGGACGCAAACGACTTCCGCCACAACGAGAAGTCCGTCAT CATGCCTGCTGCAGACACCCTCACCATCAAGCACATCGCCACCGACGGCACCGAAACCATCCTCAAAGATGGCCTCAAGG TTCTCGAAGGTGAAGTCATCGACGGCACCTTCCTGTCCGCCAAGGCTCTCGACGCCTTCCTCACCGAGCAGGTACAGCGT GCCAAGAATGAGAACGTTTTGTTCTCCGCCCACCTCAAGGCAACCATGATGAAGGTATCCGACCCCATCATCTTCGGACA CGTCGTCCGCGCCTACTTTGCCGACGTCTTTGCCACCTACGGTGACCAGCTCAACGCAGCCGGCCTCAACGGCGAAAACG GCCTTGCCGCAATCTACAGCGGCCTCGACGCCCTCGACAATGGCGCCGAGATCAAGGCAGCTTTCGACGCCGCTCTCGAA GCAGGTGCCGACGTTGCCATGGTCAACTCCGCCAAGGGAATCACCAACCTCCATGTCCCTTCCGATGTGATCATCGACGC CTCCATGCCAGCCATGATCCGCACCGCAGGCCACATGTGGAACAAGGACGATCAGGAACAAGATACCCTAGCAGTTATCC CAGACTCCTCCTACGCAGGCGTCTACCAAGTCGTCATTGAAGACTGCAAGAAGAACGGCGCCTTCGATCCCACCACCATG GGCACCGTGCCCAACGTCGGACTCATGGCACAAAAAGCCGAAGAGTACGGCTCCCACGATAAGACCTTCAAGATTGCAGC AGACGGTAAGGTAGTCGTCGTCAATGCCGCAGGCGAAGCACTCATCGAGCACGACGTAGAAGCAGGCGACATCTGGCGCG CATGCCAGGCCAAGGATGCCCCAATCCAAGACTGGGTCAAGCTCGCCGTCACCCGCTCCCGACTCTCCGGCATGCCAGCA GTATTCTGGCTCGACCCAAAGCGTGCCCACGACCGCAGCCTGATCACCCTAGTAAAGAAGTACCTCGCTGATCACGACAC CGAGGGCCTCGACATCCAGATCATGAGCCCCACCGAGGCAACTCAGTTCTCCATCGATCGCATCCGCCGCGGCGAAGACA CCATCTCCGTCACCGGCAACGTGCTGCGCGACTACAACACCGACCTATTCCCAATCCTCGAGCTCGGCACCTCCGCCAAG ATGCTCTCCGTCGTGCCACTCATGGCAGGCGGCGGACTCTTCGAAACTGGCGCCGGCGGATCTGCACCAAAGCACGTCCA ACAGCTCGTTGAAGAAAACCACCTGCGCTGGGACTCCCTCGGCGAATTCCTCGCCCTAGCAGAATCCCTGCGCCACTTCG CCAACACCGAAGGCAACACCAAGGCAGGCGTACTTGCCGACGCCCTCGATCGAGCAACCGAAACCCTCCTCAACGAGGGC TACTCCCCATCGCGCAAAGCTGGCGAAATCGACAACCGTGGCTCGCACTTCTTCCTCACCCTCAACTGGGCCAAGGAACT AGCAGCCCAAACCGACGACACCGCGCTAGCCGAAACCTTCGCACCTGTCGCCGCACAGCTCGAGGACAACAAAGACACCA TCGCAGCAGCGCTTATCGACGTCCAAGGCACACCAGTAGACCTCGGCGGCTACTACCAGCCTGACGACGCCAAGACCGCA GCAGTCATGCGCCCCGTCGCAGAATTCAATGACATCATCGATGCGCTGAAGTAA
Upstream 100 bases:
>100_bases AGGGCGTTTTTACAGCTGAAGACTGAAAAAGTGCTGGGTGACAGGTATTCTTGTCGGTTGTACTACGAGCCCAATGAATA CCTGATGAACGAGGAGACTC
Downstream 100 bases:
>100_bases GGTCGCGCTCTTTTATAGCTAAAAAATGGGAAGGAATCGACGATTCCTTCCCATTTTTTATGCCCCTGCCCCATATTTTC TCTGCGATCACCACAACCAA
Product: isocitrate dehydrogenase [NADP]
Products: NA
Alternate protein names: IDH; Oxalosuccinate decarboxylase [H]
Number of amino acids: Translated: 737; Mature: 736
Protein sequence:
>737_residues MAKIIYTRTDEAPLLATYSLKPVVEAFASTAGIEVETRDISLAGRILAQFPDYLNEDQKVDDALAELGELAKTPEANIIK LPNISASVPQLKAAIAELKAQGFALPEYPDSPATDEEKDVRARYDAVKGSAVNPVLREGNSDRRAPIAVKNFAKKNPHKM GVWSADSKTNVATMDANDFRHNEKSVIMPAADTLTIKHIATDGTETILKDGLKVLEGEVIDGTFLSAKALDAFLTEQVQR AKNENVLFSAHLKATMMKVSDPIIFGHVVRAYFADVFATYGDQLNAAGLNGENGLAAIYSGLDALDNGAEIKAAFDAALE AGADVAMVNSAKGITNLHVPSDVIIDASMPAMIRTAGHMWNKDDQEQDTLAVIPDSSYAGVYQVVIEDCKKNGAFDPTTM GTVPNVGLMAQKAEEYGSHDKTFKIAADGKVVVVNAAGEALIEHDVEAGDIWRACQAKDAPIQDWVKLAVTRSRLSGMPA VFWLDPKRAHDRSLITLVKKYLADHDTEGLDIQIMSPTEATQFSIDRIRRGEDTISVTGNVLRDYNTDLFPILELGTSAK MLSVVPLMAGGGLFETGAGGSAPKHVQQLVEENHLRWDSLGEFLALAESLRHFANTEGNTKAGVLADALDRATETLLNEG YSPSRKAGEIDNRGSHFFLTLNWAKELAAQTDDTALAETFAPVAAQLEDNKDTIAAALIDVQGTPVDLGGYYQPDDAKTA AVMRPVAEFNDIIDALK
Sequences:
>Translated_737_residues MAKIIYTRTDEAPLLATYSLKPVVEAFASTAGIEVETRDISLAGRILAQFPDYLNEDQKVDDALAELGELAKTPEANIIK LPNISASVPQLKAAIAELKAQGFALPEYPDSPATDEEKDVRARYDAVKGSAVNPVLREGNSDRRAPIAVKNFAKKNPHKM GVWSADSKTNVATMDANDFRHNEKSVIMPAADTLTIKHIATDGTETILKDGLKVLEGEVIDGTFLSAKALDAFLTEQVQR AKNENVLFSAHLKATMMKVSDPIIFGHVVRAYFADVFATYGDQLNAAGLNGENGLAAIYSGLDALDNGAEIKAAFDAALE AGADVAMVNSAKGITNLHVPSDVIIDASMPAMIRTAGHMWNKDDQEQDTLAVIPDSSYAGVYQVVIEDCKKNGAFDPTTM GTVPNVGLMAQKAEEYGSHDKTFKIAADGKVVVVNAAGEALIEHDVEAGDIWRACQAKDAPIQDWVKLAVTRSRLSGMPA VFWLDPKRAHDRSLITLVKKYLADHDTEGLDIQIMSPTEATQFSIDRIRRGEDTISVTGNVLRDYNTDLFPILELGTSAK MLSVVPLMAGGGLFETGAGGSAPKHVQQLVEENHLRWDSLGEFLALAESLRHFANTEGNTKAGVLADALDRATETLLNEG YSPSRKAGEIDNRGSHFFLTLNWAKELAAQTDDTALAETFAPVAAQLEDNKDTIAAALIDVQGTPVDLGGYYQPDDAKTA AVMRPVAEFNDIIDALK >Mature_736_residues AKIIYTRTDEAPLLATYSLKPVVEAFASTAGIEVETRDISLAGRILAQFPDYLNEDQKVDDALAELGELAKTPEANIIKL PNISASVPQLKAAIAELKAQGFALPEYPDSPATDEEKDVRARYDAVKGSAVNPVLREGNSDRRAPIAVKNFAKKNPHKMG VWSADSKTNVATMDANDFRHNEKSVIMPAADTLTIKHIATDGTETILKDGLKVLEGEVIDGTFLSAKALDAFLTEQVQRA KNENVLFSAHLKATMMKVSDPIIFGHVVRAYFADVFATYGDQLNAAGLNGENGLAAIYSGLDALDNGAEIKAAFDAALEA GADVAMVNSAKGITNLHVPSDVIIDASMPAMIRTAGHMWNKDDQEQDTLAVIPDSSYAGVYQVVIEDCKKNGAFDPTTMG TVPNVGLMAQKAEEYGSHDKTFKIAADGKVVVVNAAGEALIEHDVEAGDIWRACQAKDAPIQDWVKLAVTRSRLSGMPAV FWLDPKRAHDRSLITLVKKYLADHDTEGLDIQIMSPTEATQFSIDRIRRGEDTISVTGNVLRDYNTDLFPILELGTSAKM LSVVPLMAGGGLFETGAGGSAPKHVQQLVEENHLRWDSLGEFLALAESLRHFANTEGNTKAGVLADALDRATETLLNEGY SPSRKAGEIDNRGSHFFLTLNWAKELAAQTDDTALAETFAPVAAQLEDNKDTIAAALIDVQGTPVDLGGYYQPDDAKTAA VMRPVAEFNDIIDALK
Specific function: Unknown
COG id: COG2838
COG function: function code C; Monomeric isocitrate dehydrogenase
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the monomeric-type IDH family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001804 - InterPro: IPR004436 [H]
Pfam domain/function: PF03971 IDH [H]
EC number: =1.1.1.42 [H]
Molecular weight: Translated: 79394; Mature: 79263
Theoretical pI: Translated: 4.56; Mature: 4.56
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAKIIYTRTDEAPLLATYSLKPVVEAFASTAGIEVETRDISLAGRILAQFPDYLNEDQKV CCEEEEEECCCCCEEEEECHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCCCCHHH DDALAELGELAKTPEANIIKLPNISASVPQLKAAIAELKAQGFALPEYPDSPATDEEKDV HHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH RARYDAVKGSAVNPVLREGNSDRRAPIAVKNFAKKNPHKMGVWSADSKTNVATMDANDFR HHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHCCCCCCCCEEECCCCCCEEEECCHHCC HNEKSVIMPAADTLTIKHIATDGTETILKDGLKVLEGEVIDGTFLSAKALDAFLTEQVQR CCCCEEEEECCCEEEEEEEECCCHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHH AKNENVLFSAHLKATMMKVSDPIIFGHVVRAYFADVFATYGDQLNAAGLNGENGLAAIYS CCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH GLDALDNGAEIKAAFDAALEAGADVAMVNSAKGITNLHVPSDVIIDASMPAMIRTAGHMW HHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCCEEEECCCCHHHHHHHHCC NKDDQEQDTLAVIPDSSYAGVYQVVIEDCKKNGAFDPTTMGTVPNVGLMAQKAEEYGSHD CCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC KTFKIAADGKVVVVNAAGEALIEHDVEAGDIWRACQAKDAPIQDWVKLAVTRSRLSGMPA CEEEEECCCEEEEEECCCCHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCE VFWLDPKRAHDRSLITLVKKYLADHDTEGLDIQIMSPTEATQFSIDRIRRGEDTISVTGN EEEECCCHHCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEECHH VLRDYNTDLFPILELGTSAKMLSVVPLMAGGGLFETGAGGSAPKHVQQLVEENHLRWDSL HHHHCCCCEEHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCCCHHHH GEFLALAESLRHFANTEGNTKAGVLADALDRATETLLNEGYSPSRKAGEIDNRGSHFFLT HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEE LNWAKELAAQTDDTALAETFAPVAAQLEDNKDTIAAALIDVQGTPVDLGGYYQPDDAKTA EEHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEECCCCCHHH AVMRPVAEFNDIIDALK HHHHHHHHHHHHHHHCC >Mature Secondary Structure AKIIYTRTDEAPLLATYSLKPVVEAFASTAGIEVETRDISLAGRILAQFPDYLNEDQKV CEEEEEECCCCCEEEEECHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCCCCHHH DDALAELGELAKTPEANIIKLPNISASVPQLKAAIAELKAQGFALPEYPDSPATDEEKDV HHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHH RARYDAVKGSAVNPVLREGNSDRRAPIAVKNFAKKNPHKMGVWSADSKTNVATMDANDFR HHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHCCCCCCCCEEECCCCCCEEEECCHHCC HNEKSVIMPAADTLTIKHIATDGTETILKDGLKVLEGEVIDGTFLSAKALDAFLTEQVQR CCCCEEEEECCCEEEEEEEECCCHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHH AKNENVLFSAHLKATMMKVSDPIIFGHVVRAYFADVFATYGDQLNAAGLNGENGLAAIYS CCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH GLDALDNGAEIKAAFDAALEAGADVAMVNSAKGITNLHVPSDVIIDASMPAMIRTAGHMW HHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEECCCCCEEEECCCCHHHHHHHHCC NKDDQEQDTLAVIPDSSYAGVYQVVIEDCKKNGAFDPTTMGTVPNVGLMAQKAEEYGSHD CCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC KTFKIAADGKVVVVNAAGEALIEHDVEAGDIWRACQAKDAPIQDWVKLAVTRSRLSGMPA CEEEEECCCEEEEEECCCCHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCE VFWLDPKRAHDRSLITLVKKYLADHDTEGLDIQIMSPTEATQFSIDRIRRGEDTISVTGN EEEECCCHHCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEECHH VLRDYNTDLFPILELGTSAKMLSVVPLMAGGGLFETGAGGSAPKHVQQLVEENHLRWDSL HHHHCCCCEEHHHHCCCCHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCCCHHHH GEFLALAESLRHFANTEGNTKAGVLADALDRATETLLNEGYSPSRKAGEIDNRGSHFFLT HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEE LNWAKELAAQTDDTALAETFAPVAAQLEDNKDTIAAALIDVQGTPVDLGGYYQPDDAKTA EEHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEECCCCCHHH AVMRPVAEFNDIIDALK HHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7836312; 12948626 [H]