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The map label for this gene is kpsU [H]

Identifier: 21674644

GI number: 21674644

Start: 1735251

End: 1735997

Strand: Reverse

Name: kpsU [H]

Synonym: CT1830

Alternate gene names: 21674644

Gene position: 1735997-1735251 (Counterclockwise)

Preceding gene: 21674645

Following gene: 21674643

Centisome position: 80.56

GC content: 63.32

Gene sequence:

>747_bases
ATGAACGCCGTCATCGTCATTCCCGCCCGTCTTAGCTCCAGCCGTCTGAAAGAGAAAATGCTTGCCGATCTCGAAGGCGA
GCCGCTCATCGTGCGCACCTGGCAGCAAGCGACGAAATCGCGCCTTGCGAGCCGCGTGGTGGTGGCGACCGACAGCGAGC
GCATCTTTGCGGTGCTTCGCGAGGCCGGCGCGGAGGTGGTGATGACCTCGCCTGACCTCACCTGCGGCACCGACCGCATC
GCCGAGGCCGCTGAACAGGTGGGTGGCGACGTATTCGTCAATCTCCAGGGCGACGAACCACTCATCGACCCGGCGACTAT
CGACCTTGCCATCGCGCCCTTTTTCGGGGAGGGCCCGCTGCCCGACTGCACCACCCTGGTTTTCCCGCTCAAGCCTGATG
AACGGCAGATCATCGACGATCCACACGTGGTCAAGGCCGTGCTCGACACTCGCGGCAATGCGCTCTACTTCTCGCGCAGC
CCGATTCCGTACCGCCGTGAAACCCTGCCCGATACGAAATACTACCGCCACATCGGCCTCTACGCCTTCCGCGCCGACGT
GCTCAAAGCCTTCGTTGCGCTCCCGCCCTCGATGCTCGAACGCGCCGAATCCCTCGAACAACTCCGCCTCCTCGAAAACG
GCTACCGCATTCGCTGCATCGAAACAACGACGGATACGCCGGGCGTGAACACCGAGGAGGAGCTGGAAGAGGTGCGCAGG
CTGTTCAGGGAGCGGTTTGGAGCGTGA

Upstream 100 bases:

>100_bases
CCGGGTGCCCGGTCGAGACCGGCGTGTTCGGCGCAGACATGCAGGTGTCGCTGGTCAACGACGGCCCGGTCACCATCATT
CTCGAATCACCAAAAAAACC

Downstream 100 bases:

>100_bases
ATTGGTGAAACATCGTAACCTGCTTTGACGAGTCGTATGATTAAAAAGATAAAAGCTTTTTTTGCCGGTGCGGGCATTGG
AGCCCTTGGAGGTTTGATTG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNAVIVIPARLSSSRLKEKMLADLEGEPLIVRTWQQATKSRLASRVVVATDSERIFAVLREAGAEVVMTSPDLTCGTDRI
AEAAEQVGGDVFVNLQGDEPLIDPATIDLAIAPFFGEGPLPDCTTLVFPLKPDERQIIDDPHVVKAVLDTRGNALYFSRS
PIPYRRETLPDTKYYRHIGLYAFRADVLKAFVALPPSMLERAESLEQLRLLENGYRIRCIETTTDTPGVNTEEELEEVRR
LFRERFGA

Sequences:

>Translated_248_residues
MNAVIVIPARLSSSRLKEKMLADLEGEPLIVRTWQQATKSRLASRVVVATDSERIFAVLREAGAEVVMTSPDLTCGTDRI
AEAAEQVGGDVFVNLQGDEPLIDPATIDLAIAPFFGEGPLPDCTTLVFPLKPDERQIIDDPHVVKAVLDTRGNALYFSRS
PIPYRRETLPDTKYYRHIGLYAFRADVLKAFVALPPSMLERAESLEQLRLLENGYRIRCIETTTDTPGVNTEEELEEVRR
LFRERFGA
>Mature_248_residues
MNAVIVIPARLSSSRLKEKMLADLEGEPLIVRTWQQATKSRLASRVVVATDSERIFAVLREAGAEVVMTSPDLTCGTDRI
AEAAEQVGGDVFVNLQGDEPLIDPATIDLAIAPFFGEGPLPDCTTLVFPLKPDERQIIDDPHVVKAVLDTRGNALYFSRS
PIPYRRETLPDTKYYRHIGLYAFRADVLKAFVALPPSMLERAESLEQLRLLENGYRIRCIETTTDTPGVNTEEELEEVRR
LFRERFGA

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=255, Percent_Identity=41.1764705882353, Blast_Score=160, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27730; Mature: 27730

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVIVIPARLSSSRLKEKMLADLEGEPLIVRTWQQATKSRLASRVVVATDSERIFAVLR
CCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCEEEEEECCHHHHHHHH
EAGAEVVMTSPDLTCGTDRIAEAAEQVGGDVFVNLQGDEPLIDPATIDLAIAPFFGEGPL
HCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCC
PDCTTLVFPLKPDERQIIDDPHVVKAVLDTRGNALYFSRSPIPYRRETLPDTKYYRHIGL
CCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHCCCCHHHHHHHHH
YAFRADVLKAFVALPPSMLERAESLEQLRLLENGYRIRCIETTTDTPGVNTEEELEEVRR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHH
LFRERFGA
HHHHHHCC
>Mature Secondary Structure
MNAVIVIPARLSSSRLKEKMLADLEGEPLIVRTWQQATKSRLASRVVVATDSERIFAVLR
CCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCEEEEEECCHHHHHHHH
EAGAEVVMTSPDLTCGTDRIAEAAEQVGGDVFVNLQGDEPLIDPATIDLAIAPFFGEGPL
HCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEECCCCCCCC
PDCTTLVFPLKPDERQIIDDPHVVKAVLDTRGNALYFSRSPIPYRRETLPDTKYYRHIGL
CCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHCCCCHHHHHHHHH
YAFRADVLKAFVALPPSMLERAESLEQLRLLENGYRIRCIETTTDTPGVNTEEELEEVRR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHH
LFRERFGA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA