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The map label for this gene is dtd

Identifier: 21674645

GI number: 21674645

Start: 1735994

End: 1736446

Strand: Reverse

Name: dtd

Synonym: CT1831

Alternate gene names: 21674645

Gene position: 1736446-1735994 (Counterclockwise)

Preceding gene: 21674646

Following gene: 21674644

Centisome position: 80.58

GC content: 61.81

Gene sequence:

>453_bases
ATGAGAACGGTTGTCCAGCAGGTGCGCGAGGCGAGCGTCTCCATCGGCGGTGAGCTGCACAGCTCCATCGGTACGGGGCT
GCTGGTGCTTGCCGGAATCTCGCGCGACGACACGGCGGACGACCTCGCCTGGATGAGCCGCAAGATTCCGAATCTGCGCA
TTTTTGAGGATGAGAAGGGGAAGATGAACCGCTCGCTCAAAGATATTGGCGGCGCACTGCTCGTGGTCTCGCAATTTACG
CTTTACGCCGACGCCAGCCGCGGCAATCGCCCTGGCTTTTCCGAATCCGCGCCGCCGGAGCTTGCCAGAGTGCTGTTTGA
CCGCTTCGTCGAGTCGATCCGCCACGAGGCCGGGTGCCCGGTCGAGACCGGCGTGTTCGGCGCAGACATGCAGGTGTCGC
TGGTCAACGACGGCCCGGTCACCATCATTCTCGAATCACCAAAAAAACCATGA

Upstream 100 bases:

>100_bases
CAAGCTCCCGCAGCAAGGTGTTGAAGGTCGAAGGCGTTACGCCCGCCGCTGTGCGCGAGGCGCTTGTCGGGATGCTTGGC
GATGAAGCGGAGGCTGGCGC

Downstream 100 bases:

>100_bases
ACGCCGTCATCGTCATTCCCGCCCGTCTTAGCTCCAGCCGTCTGAAAGAGAAAATGCTTGCCGATCTCGAAGGCGAGCCG
CTCATCGTGCGCACCTGGCA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MRTVVQQVREASVSIGGELHSSIGTGLLVLAGISRDDTADDLAWMSRKIPNLRIFEDEKGKMNRSLKDIGGALLVVSQFT
LYADASRGNRPGFSESAPPELARVLFDRFVESIRHEAGCPVETGVFGADMQVSLVNDGPVTIILESPKKP

Sequences:

>Translated_150_residues
MRTVVQQVREASVSIGGELHSSIGTGLLVLAGISRDDTADDLAWMSRKIPNLRIFEDEKGKMNRSLKDIGGALLVVSQFT
LYADASRGNRPGFSESAPPELARVLFDRFVESIRHEAGCPVETGVFGADMQVSLVNDGPVTIILESPKKP
>Mature_150_residues
MRTVVQQVREASVSIGGELHSSIGTGLLVLAGISRDDTADDLAWMSRKIPNLRIFEDEKGKMNRSLKDIGGALLVVSQFT
LYADASRGNRPGFSESAPPELARVLFDRFVESIRHEAGCPVETGVFGADMQVSLVNDGPVTIILESPKKP

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=48.993288590604, Blast_Score=127, Evalue=5e-30,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=48.9655172413793, Blast_Score=139, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=39.7350993377483, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319982, Length=150, Percent_Identity=40.6666666666667, Blast_Score=114, Evalue=5e-27,
Organism=Drosophila melanogaster, GI281361569, Length=150, Percent_Identity=46, Blast_Score=127, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_CHLTE (Q8KBF6)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662710.1
- ProteinModelPortal:   Q8KBF6
- SMR:   Q8KBF6
- GeneID:   1008067
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1831
- NMPDR:   fig|194439.1.peg.1804
- TIGR:   CT1831
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   CTEP194439:CT_1831-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16225; Mature: 16225

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTVVQQVREASVSIGGELHSSIGTGLLVLAGISRDDTADDLAWMSRKIPNLRIFEDEKG
CCHHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCC
KMNRSLKDIGGALLVVSQFTLYADASRGNRPGFSESAPPELARVLFDRFVESIRHEAGCP
HHHHHHHHHCHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
VETGVFGADMQVSLVNDGPVTIILESPKKP
CCCCCCCCCEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MRTVVQQVREASVSIGGELHSSIGTGLLVLAGISRDDTADDLAWMSRKIPNLRIFEDEKG
CCHHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCC
KMNRSLKDIGGALLVVSQFTLYADASRGNRPGFSESAPPELARVLFDRFVESIRHEAGCP
HHHHHHHHHCHHHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
VETGVFGADMQVSLVNDGPVTIILESPKKP
CCCCCCCCCEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901