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The map label for this gene is gapA [H]

Identifier: 21674300

GI number: 21674300

Start: 1386853

End: 1387857

Strand: Direct

Name: gapA [H]

Synonym: CT1480

Alternate gene names: 21674300

Gene position: 1386853-1387857 (Clockwise)

Preceding gene: 21674299

Following gene: 21674302

Centisome position: 64.36

GC content: 56.92

Gene sequence:

>1005_bases
ATGGCGAAAGTAAAAGTTGGTATCAATGGTTTTGGCCGCATTGGCCGTCTGGTTTTCAGACAGGCCATGGAGAATCCTGA
AATCGAGATCGTCGGAATCAACGATCTGACCGATGTGAAAACCCTTGCCCACCTGCTCAAATACGACAGCTCCCACAAGA
AATTCAACGGTGAAGTCACGATCGAAGGCGACAATCTCATCGTCAACGGCAGAACCATCGCCATCTGTGCGCAGAAAGAT
CCCGCTCAGCTTCCCTGGGCCTCGCTCGGTGCTACCCTTGTGGTTGAATCGACCGGCATCTTCACCAGCCGCGAAGCCGC
TTCGAAACACCTCGCCGCTGGCGCGAAGAAGGTTATCATCTCCGCTCCCGCAAAAGACAAGATCGACGCCACCATCGTCA
TAGGCGTCAACGACAAGAGCATCACCGGCAAGGAGGAGATTATCTCCAACGCGAGCTGCACCACCAACTGCCTCGCCCCG
ATGACCAAGGTACTCAACGACAACTTCGGCATCGTCAAAGGCTTCATGACCACCGTGCACGCCTACACCAACGACCAGAA
CATTCTCGACCTTCCGCACAAGGATCTGCGCCGTGCACGCGCTGCGGCCTGTTCGATCATCCCGACCTCGACCGGAGCGG
CCAAAGCGATCGGCGAAGTGCTTCCCGAACTTGCCGGCAAGCTCGACGGCTTCGCCATGAGGGTCCCGATTCCAGACGGT
TCGGTCACCGACCTGTCGGTCATCATCGAGAAATCGGCCACCAAAGAGGAAATCAACGCCGTCATGAAGGCTGCCGCAGA
AGGCCCGATGAAAGGCATCCTCGAGTACAACGTCGATCCAATCGTCTCCTGCGACATCGTCGGCAACGCCCACTCTTGCA
TCTTCGACTCGCCGCTGACCATGAGCTCCGGCAACATGGTGAAAATCGTCGGCTGGTACGACAACGAACTCGGCTACGCC
ACCCGCGTGGTTGACCTGCTCGGCATCTACTCGAAGTTCGTGTAA

Upstream 100 bases:

>100_bases
TTGTTCAGTCCCGGAGAACGAGTGACGCCGTCGAGGCAACAATCCGGAACCGGGCCGTGATCATTATCGTTTTTGTTAAA
CCCATATATAAAGACCTGTT

Downstream 100 bases:

>100_bases
GAACCGGTTTCACGGAAGTTTGTAATCAGAAGGGCTGCCTGAAAAGGCGGCCCTTCTGCGTTGTAAAGAGCATTTTTCTT
ATGGGACTTATGAGAGGAAT

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAKVKVGINGFGRIGRLVFRQAMENPEIEIVGINDLTDVKTLAHLLKYDSSHKKFNGEVTIEGDNLIVNGRTIAICAQKD
PAQLPWASLGATLVVESTGIFTSREAASKHLAAGAKKVIISAPAKDKIDATIVIGVNDKSITGKEEIISNASCTTNCLAP
MTKVLNDNFGIVKGFMTTVHAYTNDQNILDLPHKDLRRARAAACSIIPTSTGAAKAIGEVLPELAGKLDGFAMRVPIPDG
SVTDLSVIIEKSATKEEINAVMKAAAEGPMKGILEYNVDPIVSCDIVGNAHSCIFDSPLTMSSGNMVKIVGWYDNELGYA
TRVVDLLGIYSKFV

Sequences:

>Translated_334_residues
MAKVKVGINGFGRIGRLVFRQAMENPEIEIVGINDLTDVKTLAHLLKYDSSHKKFNGEVTIEGDNLIVNGRTIAICAQKD
PAQLPWASLGATLVVESTGIFTSREAASKHLAAGAKKVIISAPAKDKIDATIVIGVNDKSITGKEEIISNASCTTNCLAP
MTKVLNDNFGIVKGFMTTVHAYTNDQNILDLPHKDLRRARAAACSIIPTSTGAAKAIGEVLPELAGKLDGFAMRVPIPDG
SVTDLSVIIEKSATKEEINAVMKAAAEGPMKGILEYNVDPIVSCDIVGNAHSCIFDSPLTMSSGNMVKIVGWYDNELGYA
TRVVDLLGIYSKFV
>Mature_333_residues
AKVKVGINGFGRIGRLVFRQAMENPEIEIVGINDLTDVKTLAHLLKYDSSHKKFNGEVTIEGDNLIVNGRTIAICAQKDP
AQLPWASLGATLVVESTGIFTSREAASKHLAAGAKKVIISAPAKDKIDATIVIGVNDKSITGKEEIISNASCTTNCLAPM
TKVLNDNFGIVKGFMTTVHAYTNDQNILDLPHKDLRRARAAACSIIPTSTGAAKAIGEVLPELAGKLDGFAMRVPIPDGS
VTDLSVIIEKSATKEEINAVMKAAAEGPMKGILEYNVDPIVSCDIVGNAHSCIFDSPLTMSSGNMVKIVGWYDNELGYAT
RVVDLLGIYSKFV

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=330, Percent_Identity=51.2121212121212, Blast_Score=331, Evalue=6e-91,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=49.2401215805471, Blast_Score=320, Evalue=2e-87,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=54.0785498489426, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1789295, Length=326, Percent_Identity=43.558282208589, Blast_Score=286, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI17534679, Length=337, Percent_Identity=54.8961424332344, Blast_Score=351, Evalue=3e-97,
Organism=Caenorhabditis elegans, GI17534677, Length=337, Percent_Identity=54.5994065281899, Blast_Score=350, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI32566163, Length=336, Percent_Identity=52.9761904761905, Blast_Score=336, Evalue=9e-93,
Organism=Caenorhabditis elegans, GI17568413, Length=336, Percent_Identity=52.9761904761905, Blast_Score=336, Evalue=1e-92,
Organism=Saccharomyces cerevisiae, GI6321631, Length=327, Percent_Identity=51.9877675840979, Blast_Score=339, Evalue=3e-94,
Organism=Saccharomyces cerevisiae, GI6322409, Length=332, Percent_Identity=50.6024096385542, Blast_Score=338, Evalue=7e-94,
Organism=Saccharomyces cerevisiae, GI6322468, Length=327, Percent_Identity=51.9877675840979, Blast_Score=337, Evalue=2e-93,
Organism=Drosophila melanogaster, GI85725000, Length=326, Percent_Identity=51.5337423312883, Blast_Score=326, Evalue=1e-89,
Organism=Drosophila melanogaster, GI22023983, Length=326, Percent_Identity=51.5337423312883, Blast_Score=326, Evalue=1e-89,
Organism=Drosophila melanogaster, GI17933600, Length=326, Percent_Identity=51.5337423312883, Blast_Score=326, Evalue=1e-89,
Organism=Drosophila melanogaster, GI18110149, Length=326, Percent_Identity=51.5337423312883, Blast_Score=326, Evalue=1e-89,
Organism=Drosophila melanogaster, GI19922412, Length=332, Percent_Identity=47.5903614457831, Blast_Score=307, Evalue=5e-84,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35615; Mature: 35483

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVKVGINGFGRIGRLVFRQAMENPEIEIVGINDLTDVKTLAHLLKYDSSHKKFNGEVT
CCEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEECCEEE
IEGDNLIVNGRTIAICAQKDPAQLPWASLGATLVVESTGIFTSREAASKHLAAGAKKVII
EECCEEEECCEEEEEEECCCCCCCCHHHCCCEEEEECCCCEECHHHHHHHHHCCCCEEEE
SAPAKDKIDATIVIGVNDKSITGKEEIISNASCTTNCLAPMTKVLNDNFGIVKGFMTTVH
ECCCCCCCCEEEEEECCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHE
AYTNDQNILDLPHKDLRRARAAACSIIPTSTGAAKAIGEVLPELAGKLDGFAMRVPIPDG
EECCCCCEEECCHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCC
SVTDLSVIIEKSATKEEINAVMKAAAEGPMKGILEYNVDPIVSCDIVGNAHSCIFDSPLT
CCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHEEECCCCEEEEEEECCCCCEEECCCCE
MSSGNMVKIVGWYDNELGYATRVVDLLGIYSKFV
ECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKVKVGINGFGRIGRLVFRQAMENPEIEIVGINDLTDVKTLAHLLKYDSSHKKFNGEVT
CEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEECCEEE
IEGDNLIVNGRTIAICAQKDPAQLPWASLGATLVVESTGIFTSREAASKHLAAGAKKVII
EECCEEEECCEEEEEEECCCCCCCCHHHCCCEEEEECCCCEECHHHHHHHHHCCCCEEEE
SAPAKDKIDATIVIGVNDKSITGKEEIISNASCTTNCLAPMTKVLNDNFGIVKGFMTTVH
ECCCCCCCCEEEEEECCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHE
AYTNDQNILDLPHKDLRRARAAACSIIPTSTGAAKAIGEVLPELAGKLDGFAMRVPIPDG
EECCCCCEEECCHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCC
SVTDLSVIIEKSATKEEINAVMKAAAEGPMKGILEYNVDPIVSCDIVGNAHSCIFDSPLT
CCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHEEECCCCEEEEEEECCCCCEEECCCCE
MSSGNMVKIVGWYDNELGYATRVVDLLGIYSKFV
ECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2684782; 2227448; 2656407; 7408868; 193030; 3586018; 9175858 [H]