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The map label for this gene is dnaZX [H]

Identifier: 21674147

GI number: 21674147

Start: 1246166

End: 1248028

Strand: Reverse

Name: dnaZX [H]

Synonym: CT1324

Alternate gene names: 21674147

Gene position: 1248028-1246166 (Counterclockwise)

Preceding gene: 21674148

Following gene: 21674146

Centisome position: 57.91

GC content: 58.83

Gene sequence:

>1863_bases
ATGAGTTATCAGGTTATAGCGCGAAAGTACAGGCCTTCACGGTTTGCCGACATTACCGCGCAGGAGCATATTACCGGCAC
GATCCAGAACTCACTACGGATGGGACGAGTCGGCCACGGTTACATCTTTTCGGGACTTCGGGGCGTGGGCAAGACCACGG
CGGCTCGTGTGTTTGCCAAGGCGGTCAACTGCCAGCGCATGATCGACGATCCGCAGTATCTCAAGGAGGTGACCGAGCCG
TGTGGCGTGTGCGAGAGCTGCCGCGATTTCGATGCCGGGGCGAGCCTGAACATCTCCGAGTTTGACGCCGCCTCAAACAA
CAGTGTTGACGATATCCGTCTGCTTCGCGAGAACGTGCGTTACGGCCCGCAGAAAGGACGCTATCGAGTCTACATCATCG
ATGAGGTGCACATGCTCTCGACGGCGGCATTCAACGCGTTTCTCAAGACGCTAGAAGAGCCGCCGCCGCACGCGATCTTT
ATCTTTGCAACCACCGAGCTTCACAAAATTCCGGCCACCATCGCCTCGCGCTGCCAGCGCTTCAACTTCAAGCGCATTCC
GCTTGATCGCATTCAGGGCCAGCTCCGGCAGATCTGCGACGCCGAGGGTATCACCGCTGATGCTGACGCGCTCCAGCTCA
TTGCGCGCAAGGCGCAGGGTTCGATGCGTGATGCCCAGAGCATTCTTGACCAGGTGATCGCCTTTGCTATCGACAGTGAG
GGGGAGCGCGCCATCCGCTACGACAAGGTCTCTGAGCTGTTGAGCTACATCGACGACGAACACTTTTTCATGGTGACCGA
TGCCATCGCCAACGCCGATGCCGCTGCGATGCTCGAAGTGGCGGGCATGGTCAACCGAAACGGTTACGACGAGCAGGATT
TTCTGGAAAAGCTGATCGAGCATTTCCGGAACTTTCTCATCATCCACAATTTACGGTCGAGCAAGCTGATCGAGCGTCCG
GAACCGGTGAAAGAACGCTACCAGCGAGACGCGCTGCGGCTGACGCCAGCGGCGATCATGGCGATGACCGACTTTCTCAT
GCAGACCCAGCGTGAGCTGAAGTTCTATGCCGAGCATCAGTTCCGCTTTGAGCTGGCGCTGCTCAAGCTGATTGAACTGG
GTAGGGGAGTCTGGCCATCACCAACCGCTTCGGCGGACGAAAAAAAAAAGCTTGAGCCTGTAGCTCCACCGTCCGCGCCC
GCATCTGCTGCACCGTTCAAGCCGGAACGGTCCACCCGGCGCTCGAAAACGGCATCTTCCCCGGAATCTGGTACGGCCCC
GTCCGGCTTGCCTCCGGTGCCGGAGCCGCCTCCTCTTCCGACGAAGGGGAGTGCCTCTTCGCGTCCAGCCGAATCGAAAC
TGGCGGCTTCCATCGACCTCGGCTCCTGGAAACAGGCCTTCTCCAAATTTGGCAGCAACGCTGACCAGCATCTACCGGCA
AGAAACCGGTTGCGCGTTGAGGAGAACGTTGCCGGGACGGACAGTGGCGCGCCGGTCGCGGTGCTCGAACAGTTGCGCAT
GGAGTGGGGGCGCTTCCTCGAACACCTCTCGGCCAAAGGATTGCAGGTGCTGGTATCGCATCTTCACTCATCCGAGCTGA
TGTCGTGCAGCCCTTCGGGCGTAGTGGAGCTCGGGTGCTGCCGGAAGTTTTCGTTCGAAGAGCTTCAGCACGACTCAGCC
CTACTCGAAACCGAGATGGCCGATTTTTACAGGCTGCCATTGAAACTCGCCATACGCTACGACGCCGAGCGCGACGCCTG
CACCCGTGAGAAGAGCATCTTCACCATGTTCAAAGAGCTGTCGGAAACGAACGAGGTCGTGCGTTATCTGATCAGCGAGT
TCGGCGGTGAGCTGGTTTACTGA

Upstream 100 bases:

>100_bases
GCGAATTCGAGCCGCTCCGGGCAGAGGTCCGCGAAGCGCTCAGGAGCGCGATGCAGACGCCGCTGATTACGCTGGTGAAC
GATTCAACGGAAAAGGATTC

Downstream 100 bases:

>100_bases
GCGTAAAGGGTTTTAGAATTCGCGCAAAATTCCTGATATTCAGGGTCGTTTTTATAGAATTCTTGTTCCGGCAGTGATCG
GGATTATGACATTTTTTCAC

Product: DNA polymerase III, gamma/tau subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MSYQVIARKYRPSRFADITAQEHITGTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDDPQYLKEVTEP
CGVCESCRDFDAGASLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIF
IFATTELHKIPATIASRCQRFNFKRIPLDRIQGQLRQICDAEGITADADALQLIARKAQGSMRDAQSILDQVIAFAIDSE
GERAIRYDKVSELLSYIDDEHFFMVTDAIANADAAAMLEVAGMVNRNGYDEQDFLEKLIEHFRNFLIIHNLRSSKLIERP
EPVKERYQRDALRLTPAAIMAMTDFLMQTQRELKFYAEHQFRFELALLKLIELGRGVWPSPTASADEKKKLEPVAPPSAP
ASAAPFKPERSTRRSKTASSPESGTAPSGLPPVPEPPPLPTKGSASSRPAESKLAASIDLGSWKQAFSKFGSNADQHLPA
RNRLRVEENVAGTDSGAPVAVLEQLRMEWGRFLEHLSAKGLQVLVSHLHSSELMSCSPSGVVELGCCRKFSFEELQHDSA
LLETEMADFYRLPLKLAIRYDAERDACTREKSIFTMFKELSETNEVVRYLISEFGGELVY

Sequences:

>Translated_620_residues
MSYQVIARKYRPSRFADITAQEHITGTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDDPQYLKEVTEP
CGVCESCRDFDAGASLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIF
IFATTELHKIPATIASRCQRFNFKRIPLDRIQGQLRQICDAEGITADADALQLIARKAQGSMRDAQSILDQVIAFAIDSE
GERAIRYDKVSELLSYIDDEHFFMVTDAIANADAAAMLEVAGMVNRNGYDEQDFLEKLIEHFRNFLIIHNLRSSKLIERP
EPVKERYQRDALRLTPAAIMAMTDFLMQTQRELKFYAEHQFRFELALLKLIELGRGVWPSPTASADEKKKLEPVAPPSAP
ASAAPFKPERSTRRSKTASSPESGTAPSGLPPVPEPPPLPTKGSASSRPAESKLAASIDLGSWKQAFSKFGSNADQHLPA
RNRLRVEENVAGTDSGAPVAVLEQLRMEWGRFLEHLSAKGLQVLVSHLHSSELMSCSPSGVVELGCCRKFSFEELQHDSA
LLETEMADFYRLPLKLAIRYDAERDACTREKSIFTMFKELSETNEVVRYLISEFGGELVY
>Mature_619_residues
SYQVIARKYRPSRFADITAQEHITGTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDDPQYLKEVTEPC
GVCESCRDFDAGASLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFI
FATTELHKIPATIASRCQRFNFKRIPLDRIQGQLRQICDAEGITADADALQLIARKAQGSMRDAQSILDQVIAFAIDSEG
ERAIRYDKVSELLSYIDDEHFFMVTDAIANADAAAMLEVAGMVNRNGYDEQDFLEKLIEHFRNFLIIHNLRSSKLIERPE
PVKERYQRDALRLTPAAIMAMTDFLMQTQRELKFYAEHQFRFELALLKLIELGRGVWPSPTASADEKKKLEPVAPPSAPA
SAAPFKPERSTRRSKTASSPESGTAPSGLPPVPEPPPLPTKGSASSRPAESKLAASIDLGSWKQAFSKFGSNADQHLPAR
NRLRVEENVAGTDSGAPVAVLEQLRMEWGRFLEHLSAKGLQVLVSHLHSSELMSCSPSGVVELGCCRKFSFEELQHDSAL
LETEMADFYRLPLKLAIRYDAERDACTREKSIFTMFKELSETNEVVRYLISEFGGELVY

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=397, Percent_Identity=37.27959697733, Blast_Score=276, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17554730, Length=221, Percent_Identity=26.2443438914027, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324478, Length=324, Percent_Identity=23.1481481481481, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322528, Length=305, Percent_Identity=21.3114754098361, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19921076, Length=238, Percent_Identity=23.9495798319328, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 69351; Mature: 69220

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQVIARKYRPSRFADITAQEHITGTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAK
CCHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHH
AVNCQRMIDDPQYLKEVTEPCGVCESCRDFDAGASLNISEFDAASNNSVDDIRLLRENVR
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHC
YGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQR
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHH
FNFKRIPLDRIQGQLRQICDAEGITADADALQLIARKAQGSMRDAQSILDQVIAFAIDSE
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
GERAIRYDKVSELLSYIDDEHFFMVTDAIANADAAAMLEVAGMVNRNGYDEQDFLEKLIE
CCHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
HFRNFLIIHNLRSSKLIERPEPVKERYQRDALRLTPAAIMAMTDFLMQTQRELKFYAEHQ
HHHHHEEHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRFELALLKLIELGRGVWPSPTASADEKKKLEPVAPPSAPASAAPFKPERSTRRSKTASS
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCC
PESGTAPSGLPPVPEPPPLPTKGSASSRPAESKLAASIDLGSWKQAFSKFGSNADQHLPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHCCCC
RNRLRVEENVAGTDSGAPVAVLEQLRMEWGRFLEHLSAKGLQVLVSHLHSSELMSCSPSG
CCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VVELGCCRKFSFEELQHDSALLETEMADFYRLPLKLAIRYDAERDACTREKSIFTMFKEL
CEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCHHHHHHHHHHHHHHHHH
SETNEVVRYLISEFGGELVY
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SYQVIARKYRPSRFADITAQEHITGTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAK
CHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHH
AVNCQRMIDDPQYLKEVTEPCGVCESCRDFDAGASLNISEFDAASNNSVDDIRLLRENVR
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHC
YGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQR
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHH
FNFKRIPLDRIQGQLRQICDAEGITADADALQLIARKAQGSMRDAQSILDQVIAFAIDSE
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
GERAIRYDKVSELLSYIDDEHFFMVTDAIANADAAAMLEVAGMVNRNGYDEQDFLEKLIE
CCHHHHHHHHHHHHHHHCCCCEEEEEHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
HFRNFLIIHNLRSSKLIERPEPVKERYQRDALRLTPAAIMAMTDFLMQTQRELKFYAEHQ
HHHHHEEHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRFELALLKLIELGRGVWPSPTASADEKKKLEPVAPPSAPASAAPFKPERSTRRSKTASS
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCC
PESGTAPSGLPPVPEPPPLPTKGSASSRPAESKLAASIDLGSWKQAFSKFGSNADQHLPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHCCCC
RNRLRVEENVAGTDSGAPVAVLEQLRMEWGRFLEHLSAKGLQVLVSHLHSSELMSCSPSG
CCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VVELGCCRKFSFEELQHDSALLETEMADFYRLPLKLAIRYDAERDACTREKSIFTMFKEL
CEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCHHHHHHHHHHHHHHHHH
SETNEVVRYLISEFGGELVY
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]