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The map label for this gene is ndhA [H]

Identifier: 21673600

GI number: 21673600

Start: 742216

End: 743295

Strand: Direct

Name: ndhA [H]

Synonym: CT0770

Alternate gene names: 21673600

Gene position: 742216-743295 (Clockwise)

Preceding gene: 21673599

Following gene: 21673601

Centisome position: 34.44

GC content: 56.02

Gene sequence:

>1080_bases
ATGAGTTCATCACCATCTCTCAATACCTGGTCCGACGCCCTTTCAGGTTTCTCCATCGGCTGGTTTCCGCTCGGGCTGGT
TATCGTTGCGGCTATTCCGCTCGTGTTCATCGCACTCTACGCGCTGACCTACGGTGTGTATGGCGAGCGCAAGATTTCAG
CTTTCATGCAGGACAGGCTTGGTCCTATGGAGGTTGGTTTCTGGGGTCTTCTGCAGACGCTTGCCGATATTCTGAAGCTT
CTCCAGAAAGAGGATATCGTGCCGACCGTGGCCGACAAATTCCTTTTCGTGATCGGCCCCGGCATCCTGTTCGTTGGTTC
GTTCCTTGCCTTTGCAGTCTTGCCCTTTGGCCCGGCCTTCATCGGCGCAGACCTGAATGTTGGTCTGTTCTACGCTGTCG
GCATCGTGGCTATCGAGGTGGTCGGTATCCTTGCCGCCGGCTGGGGTTCGAACAACAAGTGGGCGCTTTACGGCGCGGTT
CGCAGCGTCGCCCAGATTGTCAGCTATGAAATTCCTGCTTCCATCGCTCTCCTGTGCGCCGCCATGCTGGCCGGCACTCT
GAGCATGCAGCAGATTATCCTGATGCAGGCCGGCCCGAATGGCTTCCTGCACTGGTTCCTCTTCACCAATCCGATCGCGT
GGCTGCCTTTTCTGATCTACTTTATCTCCTCGCTTGCCGAGACCAACCGCGCACCGTTCGATATTCCTGAGGCTGAATCC
GAGCTGGTTGCTGGCTACTTCACCGAGTATAGCGGCATGAAGTTCGCCGTGATCTTCCTGGCCGAGTATGGCAGCATGTT
CATGGTGTCGGCGATCATCTCCATCGCGTTCCTCGGCGGCTGGACTTCGCCGCTGCCGAACATCGGCGGTCTCGAACTGA
ACACCATGACCAGCGGTCCGGTTTGGGGTGCCTTCTGGATCATCATGAAAGGATTCTTCTTCATTTTCGTGCAGATGTGG
CTTCGCTGGACGCTTCCCCGACTCAGGGTTGACCAGCTCATGTATCTCTGCTGGAAGGTGTTGACGCCTTTTTCCCTGGT
TTCATTTGTGCTGACAGCCATCTGGGTGATCAACCATTAA

Upstream 100 bases:

>100_bases
TGGTGGCCATCATTGGCAGCATCGATATCGTGCTGGGTGAAGTTGACCGCTGACCGTTTTCAAGACAACACTTTTATTTC
AAGAAGGTTCGCCTATTGAT

Downstream 100 bases:

>100_bases
TCGTGAGGCTGGCTCAAGAGAGAATACAAAGGCAAGCAAGACGAACAACAAACTATGAGTGAGTACTTCAGCAATATAAA
GACCAGTGTGACCACCATCG

Product: NADH dehydrogenase I, subunit 1

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSSSPSLNTWSDALSGFSIGWFPLGLVIVAAIPLVFIALYALTYGVYGERKISAFMQDRLGPMEVGFWGLLQTLADILKL
LQKEDIVPTVADKFLFVIGPGILFVGSFLAFAVLPFGPAFIGADLNVGLFYAVGIVAIEVVGILAAGWGSNNKWALYGAV
RSVAQIVSYEIPASIALLCAAMLAGTLSMQQIILMQAGPNGFLHWFLFTNPIAWLPFLIYFISSLAETNRAPFDIPEAES
ELVAGYFTEYSGMKFAVIFLAEYGSMFMVSAIISIAFLGGWTSPLPNIGGLELNTMTSGPVWGAFWIIMKGFFFIFVQMW
LRWTLPRLRVDQLMYLCWKVLTPFSLVSFVLTAIWVINH

Sequences:

>Translated_359_residues
MSSSPSLNTWSDALSGFSIGWFPLGLVIVAAIPLVFIALYALTYGVYGERKISAFMQDRLGPMEVGFWGLLQTLADILKL
LQKEDIVPTVADKFLFVIGPGILFVGSFLAFAVLPFGPAFIGADLNVGLFYAVGIVAIEVVGILAAGWGSNNKWALYGAV
RSVAQIVSYEIPASIALLCAAMLAGTLSMQQIILMQAGPNGFLHWFLFTNPIAWLPFLIYFISSLAETNRAPFDIPEAES
ELVAGYFTEYSGMKFAVIFLAEYGSMFMVSAIISIAFLGGWTSPLPNIGGLELNTMTSGPVWGAFWIIMKGFFFIFVQMW
LRWTLPRLRVDQLMYLCWKVLTPFSLVSFVLTAIWVINH
>Mature_358_residues
SSSPSLNTWSDALSGFSIGWFPLGLVIVAAIPLVFIALYALTYGVYGERKISAFMQDRLGPMEVGFWGLLQTLADILKLL
QKEDIVPTVADKFLFVIGPGILFVGSFLAFAVLPFGPAFIGADLNVGLFYAVGIVAIEVVGILAAGWGSNNKWALYGAVR
SVAQIVSYEIPASIALLCAAMLAGTLSMQQIILMQAGPNGFLHWFLFTNPIAWLPFLIYFISSLAETNRAPFDIPEAESE
LVAGYFTEYSGMKFAVIFLAEYGSMFMVSAIISIAFLGGWTSPLPNIGGLELNTMTSGPVWGAFWIIMKGFFFIFVQMWL
RWTLPRLRVDQLMYLCWKVLTPFSLVSFVLTAIWVINH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=306, Percent_Identity=34.3137254901961, Blast_Score=176, Evalue=3e-44,
Organism=Escherichia coli, GI1788618, Length=330, Percent_Identity=35.4545454545455, Blast_Score=208, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 39476; Mature: 39345

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSPSLNTWSDALSGFSIGWFPLGLVIVAAIPLVFIALYALTYGVYGERKISAFMQDRL
CCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
GPMEVGFWGLLQTLADILKLLQKEDIVPTVADKFLFVIGPGILFVGSFLAFAVLPFGPAF
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IGADLNVGLFYAVGIVAIEVVGILAAGWGSNNKWALYGAVRSVAQIVSYEIPASIALLCA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHH
AMLAGTLSMQQIILMQAGPNGFLHWFLFTNPIAWLPFLIYFISSLAETNRAPFDIPEAES
HHHHHHHHHHHHHHEECCCCCCEEHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
ELVAGYFTEYSGMKFAVIFLAEYGSMFMVSAIISIAFLGGWTSPLPNIGGLELNTMTSGP
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCC
VWGAFWIIMKGFFFIFVQMWLRWTLPRLRVDQLMYLCWKVLTPFSLVSFVLTAIWVINH
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSSPSLNTWSDALSGFSIGWFPLGLVIVAAIPLVFIALYALTYGVYGERKISAFMQDRL
CCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
GPMEVGFWGLLQTLADILKLLQKEDIVPTVADKFLFVIGPGILFVGSFLAFAVLPFGPAF
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IGADLNVGLFYAVGIVAIEVVGILAAGWGSNNKWALYGAVRSVAQIVSYEIPASIALLCA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHH
AMLAGTLSMQQIILMQAGPNGFLHWFLFTNPIAWLPFLIYFISSLAETNRAPFDIPEAES
HHHHHHHHHHHHHHEECCCCCCEEHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
ELVAGYFTEYSGMKFAVIFLAEYGSMFMVSAIISIAFLGGWTSPLPNIGGLELNTMTSGP
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCC
VWGAFWIIMKGFFFIFVQMWLRWTLPRLRVDQLMYLCWKVLTPFSLVSFVLTAIWVINH
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA