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The map label for this gene is ftsW [H]

Identifier: 21672876

GI number: 21672876

Start: 31609

End: 32775

Strand: Reverse

Name: ftsW [H]

Synonym: CT0035

Alternate gene names: 21672876

Gene position: 32775-31609 (Counterclockwise)

Preceding gene: 21672877

Following gene: 21672875

Centisome position: 1.52

GC content: 59.47

Gene sequence:

>1167_bases
ATGGCGTCGCTGCTGCCCTCGACCGGACGGGGCGAAAACATCGCCGGCAAGCTGCTGCTCCTGATCGTCGCGCTGCTGAT
GTGCATCGGAGTGGTCGTCGTTTACAGTAGCGGAGCCGGGTGGGCGGAACAGAAATTTTCCGACCCGCAGTACTTCCTCT
GGCGGCAGCTCACTTTTGCCATTGCTGGCATGGCGGTGATCTTCGTGGTTGGCGCCATCGACTACCATATCTTCAGAAAG
ATCAGCAAACTGTTTCTTTTTGTCAGCATCGGTCTGTTGGCCATTTTGCTGTTGCTCAAGCTGGCGCATGTCATTCACGG
CGCCGCCCGCTGGCTCGGATTTGGCCCGCTGAAGTTCCAGGCTTCGGATCTGGCCAAATACGCCATCATTTTTCACTTTT
CCCGGCTGCTCTCTGAAAAGAGAGCGTATATCAAGGATCTGCATGACGGGTACTATCCGATGCTGGTGCTCCTGATGATC
GTTGTTGCGCTGGTGGCGCTCGAGCCGAACTTCAGCACCGCCTCGATCATCGCGATCATCGGCTTCACGCTGATGTTCAT
CGGCGGCATCCGGATCAAGTATCTGCTTGCCACCGCTTCGCTGCTGATCCCGATTGCGGCAGTCTTCGCGATTGCCGCGC
CCTACCGCGTCGCCCGCCTCGTCTCGTTCGGCGGCGGCGAGAAGGAGCTGAGCTACCAGGTGCGCCAGGCGCTGCTCGGC
CTCGGCAACGGCGGCCTGTTCGGTCTTGGCCTCGGGGCCAGCAAACAGCGGGAGCTTTACCTGCCGCTGTCGTACAACGA
CTTCGTCTTCGTTATCATCGGCGAGGAGTACGGCTTTATCGGTGCGCTGGTTATCCTGCTGCTCTTTTCCGGGCTGTTTG
CCTGTGGCATCATCATCGCCAAGCACGCTCCCGACCTGTTCGGACGCTACGTCGCCATCGGCGTCACCTTCGCCATTGTC
TTCTTCGCATTCATCAACATCGCCGTGGCCTGCCACCTCATGCCGACCACCGGTGTGGCGCTGCCGTTCATCAGCTACGG
CGGCACGGCGCTGCTGTTCAACTCGCTCGGCATCGGGCTTCTGGTCAGCATTTCACGTTACCGGAAAAAGGTCGAAACCA
TCGAGCGGGCGCAGGCGCTGCTCGAATCGAAGGGAGGTTCCTTATGA

Upstream 100 bases:

>100_bases
GCGGGCGCCAGTTCAAGCAACTTGTCCGGGAGCTGACATGAAGCTGAATGACCTTAAACTGAATTTCGATCTGGAGCTTG
ACGACGCTCCCGCCGAATCG

Downstream 100 bases:

>100_bases
AAGTGCTCTTCGCAGGTGGCGGCACCGGCGGACACCTTTACCCCGGTGTGGCGATGGCGGCGGAGCTGAAGAAGCGGGTG
CCTGGTATCAGCATCTCCTT

Product: cell cycle protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MASLLPSTGRGENIAGKLLLLIVALLMCIGVVVVYSSGAGWAEQKFSDPQYFLWRQLTFAIAGMAVIFVVGAIDYHIFRK
ISKLFLFVSIGLLAILLLLKLAHVIHGAARWLGFGPLKFQASDLAKYAIIFHFSRLLSEKRAYIKDLHDGYYPMLVLLMI
VVALVALEPNFSTASIIAIIGFTLMFIGGIRIKYLLATASLLIPIAAVFAIAAPYRVARLVSFGGGEKELSYQVRQALLG
LGNGGLFGLGLGASKQRELYLPLSYNDFVFVIIGEEYGFIGALVILLLFSGLFACGIIIAKHAPDLFGRYVAIGVTFAIV
FFAFINIAVACHLMPTTGVALPFISYGGTALLFNSLGIGLLVSISRYRKKVETIERAQALLESKGGSL

Sequences:

>Translated_388_residues
MASLLPSTGRGENIAGKLLLLIVALLMCIGVVVVYSSGAGWAEQKFSDPQYFLWRQLTFAIAGMAVIFVVGAIDYHIFRK
ISKLFLFVSIGLLAILLLLKLAHVIHGAARWLGFGPLKFQASDLAKYAIIFHFSRLLSEKRAYIKDLHDGYYPMLVLLMI
VVALVALEPNFSTASIIAIIGFTLMFIGGIRIKYLLATASLLIPIAAVFAIAAPYRVARLVSFGGGEKELSYQVRQALLG
LGNGGLFGLGLGASKQRELYLPLSYNDFVFVIIGEEYGFIGALVILLLFSGLFACGIIIAKHAPDLFGRYVAIGVTFAIV
FFAFINIAVACHLMPTTGVALPFISYGGTALLFNSLGIGLLVSISRYRKKVETIERAQALLESKGGSL
>Mature_387_residues
ASLLPSTGRGENIAGKLLLLIVALLMCIGVVVVYSSGAGWAEQKFSDPQYFLWRQLTFAIAGMAVIFVVGAIDYHIFRKI
SKLFLFVSIGLLAILLLLKLAHVIHGAARWLGFGPLKFQASDLAKYAIIFHFSRLLSEKRAYIKDLHDGYYPMLVLLMIV
VALVALEPNFSTASIIAIIGFTLMFIGGIRIKYLLATASLLIPIAAVFAIAAPYRVARLVSFGGGEKELSYQVRQALLGL
GNGGLFGLGLGASKQRELYLPLSYNDFVFVIIGEEYGFIGALVILLLFSGLFACGIIIAKHAPDLFGRYVAIGVTFAIVF
FAFINIAVACHLMPTTGVALPFISYGGTALLFNSLGIGLLVSISRYRKKVETIERAQALLESKGGSL

Specific function: May play an essential role not only during sporulation, but also during vegetative growth [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=374, Percent_Identity=27.807486631016, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786853, Length=271, Percent_Identity=32.4723247232472, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437
- InterPro:   IPR013438 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41999; Mature: 41868

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASLLPSTGRGENIAGKLLLLIVALLMCIGVVVVYSSGAGWAEQKFSDPQYFLWRQLTFA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHH
IAGMAVIFVVGAIDYHIFRKISKLFLFVSIGLLAILLLLKLAHVIHGAARWLGFGPLKFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEC
ASDLAKYAIIFHFSRLLSEKRAYIKDLHDGYYPMLVLLMIVVALVALEPNFSTASIIAII
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
GFTLMFIGGIRIKYLLATASLLIPIAAVFAIAAPYRVARLVSFGGGEKELSYQVRQALLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LGNGGLFGLGLGASKQRELYLPLSYNDFVFVIIGEEYGFIGALVILLLFSGLFACGIIIA
CCCCCEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
KHAPDLFGRYVAIGVTFAIVFFAFINIAVACHLMPTTGVALPFISYGGTALLFNSLGIGL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHCCHHH
LVSISRYRKKVETIERAQALLESKGGSL
HHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2115675; 3098901; 9384377; 8436954; 1391053 [H]