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The map label for this gene is murG

Identifier: 21672875

GI number: 21672875

Start: 30518

End: 31612

Strand: Reverse

Name: murG

Synonym: CT0034

Alternate gene names: 21672875

Gene position: 31612-30518 (Counterclockwise)

Preceding gene: 21672876

Following gene: 21672874

Centisome position: 1.47

GC content: 64.29

Gene sequence:

>1095_bases
ATGAAAGTGCTCTTCGCAGGTGGCGGCACCGGCGGACACCTTTACCCCGGTGTGGCGATGGCGGCGGAGCTGAAGAAGCG
GGTGCCTGGTATCAGCATCTCCTTCGCAGGTACCTCCGCCGGAATCGAGGCAACCGAGGTGCCGCGCCTCGGCTACCGGC
TCGTACTCTTTCCGGTCAGGGGGCTGAAGCGCGGTTTGTCGATCCGAGCGCTGGTGGAGAACGCACTCATTCTCGGCGAC
TTCGCCAAATCGCTCTCGATGGCAATGGCGCTTGTGCGCAAGGAGCAGCCCGACGTGGTGGTGGGTACGGGCGGCTACGT
CAGCGCGCCGCTGCTCCTCGCCGCGCAGCTTTCGGGCAAGAAGACACTGATTCAGGAGCAGAATGCTTTTCCGGGAGTGA
CGACGCGACTGCTGGCGCGCATGGCGACCGAGGTGCATCTGTCGTTCGAGGAGAGCCGGAAGTTTTTCGGAGGAAAATCC
GAGGTGTTCGTGACCGGCAATCCGGCGCGGGAGTTTCCCGCCGAGAGCCGGGAGTCGTGCCTCGACTTTTTCGGCCTCGA
CCGGAGTTTGCCGACGCTGCTGGTCTTCGGTGGAAGCCGTGGGGCGCGGGCGATCAACAACGCCGTGCTGAAGCTGTGCC
ATCGTCTCGAAGGCACGGTCAACCTCATCTGGCAGACCGGCGCGCTTGACGCCGACCGGATGCGCGGGGAGATCGGCACT
TCGGCAACTCGCTGGATCGGTCCCTACATTCAGGAGATGGGCAAGGCGTACGGAGCCGCCGATCTGGTGCTTTGCCGGGC
GGGGGCTTCGAGCCTTGCCGAGCTGACCAACCTCGGCAAGCCCTCGGTGCTGATCCCCTATCCCTACGCGGCGGCTGATC
ACCAGCGCCACAACGCGATGGCGCTGGTGAGCGCGGGCGCATCGGTCATGATCGACGACTCAAAGATCGGCGAAGAAGCG
TCGTTCGACGTGATCCTCACACTGCTCCGCGACCGCGAGAAACTCGCGCAAATGGGCGAGGCGGCCCGGCGAGAGGGTCA
TCCCGGCGCGGCGGCGACACTCGCGGAAAGAATCATCGCGCTATCAAAATCATAA

Upstream 100 bases:

>100_bases
CGCTCGGCATCGGGCTTCTGGTCAGCATTTCACGTTACCGGAAAAAGGTCGAAACCATCGAGCGGGCGCAGGCGCTGCTC
GAATCGAAGGGAGGTTCCTT

Downstream 100 bases:

>100_bases
GGAGTGCCCCCCATGGAACTGGGAAAAACAAAGAATGTGCATATCGTCGGCATCGGCGGCGCGGGAATGAGCGCCATCGC
CGAACTGCTGCTGAAATCGG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKVLFAGGGTGGHLYPGVAMAAELKKRVPGISISFAGTSAGIEATEVPRLGYRLVLFPVRGLKRGLSIRALVENALILGD
FAKSLSMAMALVRKEQPDVVVGTGGYVSAPLLLAAQLSGKKTLIQEQNAFPGVTTRLLARMATEVHLSFEESRKFFGGKS
EVFVTGNPAREFPAESRESCLDFFGLDRSLPTLLVFGGSRGARAINNAVLKLCHRLEGTVNLIWQTGALDADRMRGEIGT
SATRWIGPYIQEMGKAYGAADLVLCRAGASSLAELTNLGKPSVLIPYPYAAADHQRHNAMALVSAGASVMIDDSKIGEEA
SFDVILTLLRDREKLAQMGEAARREGHPGAAATLAERIIALSKS

Sequences:

>Translated_364_residues
MKVLFAGGGTGGHLYPGVAMAAELKKRVPGISISFAGTSAGIEATEVPRLGYRLVLFPVRGLKRGLSIRALVENALILGD
FAKSLSMAMALVRKEQPDVVVGTGGYVSAPLLLAAQLSGKKTLIQEQNAFPGVTTRLLARMATEVHLSFEESRKFFGGKS
EVFVTGNPAREFPAESRESCLDFFGLDRSLPTLLVFGGSRGARAINNAVLKLCHRLEGTVNLIWQTGALDADRMRGEIGT
SATRWIGPYIQEMGKAYGAADLVLCRAGASSLAELTNLGKPSVLIPYPYAAADHQRHNAMALVSAGASVMIDDSKIGEEA
SFDVILTLLRDREKLAQMGEAARREGHPGAAATLAERIIALSKS
>Mature_364_residues
MKVLFAGGGTGGHLYPGVAMAAELKKRVPGISISFAGTSAGIEATEVPRLGYRLVLFPVRGLKRGLSIRALVENALILGD
FAKSLSMAMALVRKEQPDVVVGTGGYVSAPLLLAAQLSGKKTLIQEQNAFPGVTTRLLARMATEVHLSFEESRKFFGGKS
EVFVTGNPAREFPAESRESCLDFFGLDRSLPTLLVFGGSRGARAINNAVLKLCHRLEGTVNLIWQTGALDADRMRGEIGT
SATRWIGPYIQEMGKAYGAADLVLCRAGASSLAELTNLGKPSVLIPYPYAAADHQRHNAMALVSAGASVMIDDSKIGEEA
SFDVILTLLRDREKLAQMGEAARREGHPGAAATLAERIIALSKS

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=374, Percent_Identity=31.0160427807487, Blast_Score=151, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_CHLTE (Q8KGD4)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_660940.1
- ProteinModelPortal:   Q8KGD4
- SMR:   Q8KGD4
- GeneID:   1006452
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0034
- NMPDR:   fig|194439.1.peg.34
- TIGR:   CT0034
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   CTEP194439:CT_0034-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38709; Mature: 38709

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLFAGGGTGGHLYPGVAMAAELKKRVPGISISFAGTSAGIEATEVPRLGYRLVLFPVR
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHCCCCCCCEEEEEEHH
GLKRGLSIRALVENALILGDFAKSLSMAMALVRKEQPDVVVGTGGYVSAPLLLAAQLSGK
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCC
KTLIQEQNAFPGVTTRLLARMATEVHLSFEESRKFFGGKSEVFVTGNPAREFPAESRESC
HHHHHCCCCCCCHHHHHHHHHHHHHEEEHHHHHHHCCCCCEEEEECCCHHHCCCHHHHHH
LDFFGLDRSLPTLLVFGGSRGARAINNAVLKLCHRLEGTVNLIWQTGALDADRMRGEIGT
HHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCC
SATRWIGPYIQEMGKAYGAADLVLCRAGASSLAELTNLGKPSVLIPYPYAAADHQRHNAM
CHHHHHHHHHHHHHHHHCCHHHEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEE
ALVSAGASVMIDDSKIGEEASFDVILTLLRDREKLAQMGEAARREGHPGAAATLAERIIA
EEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LSKS
HCCC
>Mature Secondary Structure
MKVLFAGGGTGGHLYPGVAMAAELKKRVPGISISFAGTSAGIEATEVPRLGYRLVLFPVR
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHCCCCCCCEEEEEEHH
GLKRGLSIRALVENALILGDFAKSLSMAMALVRKEQPDVVVGTGGYVSAPLLLAAQLSGK
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCC
KTLIQEQNAFPGVTTRLLARMATEVHLSFEESRKFFGGKSEVFVTGNPAREFPAESRESC
HHHHHCCCCCCCHHHHHHHHHHHHHEEEHHHHHHHCCCCCEEEEECCCHHHCCCHHHHHH
LDFFGLDRSLPTLLVFGGSRGARAINNAVLKLCHRLEGTVNLIWQTGALDADRMRGEIGT
HHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHCCCCC
SATRWIGPYIQEMGKAYGAADLVLCRAGASSLAELTNLGKPSVLIPYPYAAADHQRHNAM
CHHHHHHHHHHHHHHHHCCHHHEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEE
ALVSAGASVMIDDSKIGEEASFDVILTLLRDREKLAQMGEAARREGHPGAAATLAERIIA
EEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LSKS
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12093901