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The map label for this gene is topR-2

Identifier: 15897842

GI number: 15897842

Start: 817144

End: 820644

Strand: Direct

Name: topR-2

Synonym: SSO0963

Alternate gene names: 15897842

Gene position: 817144-820644 (Clockwise)

Preceding gene: 15897838

Following gene: 15897845

Centisome position: 27.31

GC content: 33.25

Gene sequence:

>3501_bases
ATGATTAATGTAATGTATAAAAATTCCTGCCCTAACTGTGGTGGGGACATTTCTGGTGACAGATTGCTGAATGGTCTGCC
ATGTGAGGCTTGTTTACCTTATATTAACGGAATAGATGATGTAGACCATATTTCAAAGGTAAAAACGTTATACAATATTT
TACTTAATAACGATAAAATTAAAAATTATTGGAATTTATATTATAACATCACTACATTTGAAACTGTCTTTAAATATTTT
AGAGATAAAACTGGATATGAACCTTGGTCTCTCCAGAAACTATGGTTAAGAAGGCTTGCGAGTAATCAGAGTTTCACTAT
GTCAGCTCCAACTGGATTGGGGAAGACAACCACATTGATGACCTATTCTGTCTTTATTGGCCAAGATGTAGTATATATCG
TTCCCACAAAGTCCTTAATGGAACAAGTATGTAAAAGATTAGAGAAATTAGGTGCTCAAGTATCTTGTGGTAAAATTGAT
CAAAAGAAAGTAAGCGTAATAACAATAAGTTACCTAAATAAGAACGCGGACTCGATAGTAAGCCTTAAGCCAAACTTTGT
CGTAATAGATGATGCAGATGCCGTAATAAAGAGCGGTAAAACAACTGATAGACTTGTTAGCTTATTGGGGATTCCGAAGG
ACGTTTATGAGAGTGCGATTCAACTAATTAGGCTAAGGAATAAATACTATTTCTCTAACGAATACACGGAAGAAGTTAAA
GAAAAAATTAGAGAATTGGAGCTTAAGATAGCAGAATTTAAGGATAAAATTTCACAGCTAGTTATAGCTAGTGCTACAAT
ACGACCTAAAGGCATTAAGCAAAAAGCTTTAAGGTTATTAACAGGTTTTGAACCTTCTTCTATTCAGTTATATGCTAGGA
ATATAATTGATGCTTATACTGAAAATCTAGATCTTTCAATAGTCAAGGAATTAGGAAGTGGTGGGTTAATTCTAGTTTCG
AAAGAATATGGTAGGTCCAAATTAAATGAAATAAAGAAATACGTTGAGGACTTAGGTTTTAACGCTAAATTAGCAATAAG
TGGAAGGAAATTCCTCGACGATTTCTCTCAAGGTAAAGTAGATATTCTAGTAGGTTCTGCGTCTTATTATGGTGTTGCCG
TTAGAGGAATTGATGAACCTAAAAGATTAAAATACGTCATATATTATGGAGTACCTAAAATAAGAGCTAAGCTTTTTGAC
GCTTTATCTAATCCATTTACATTACTCAGAGTAGGTAAATTAATTGGAATCGATTTTTCAAAGTTACAGAATAAGATTTT
AATTCTGAATCCTTCTGAAGTTCAATTATTGAAGTTTTCCATAATAAAAGGAGAAAGTATAAACTACCATAAGTTAGAAC
AATTGAGGCAAGAATTGCTATATTATATGTCATTAGTTAAAGATAAGTTGAAGGAGAAAGTCGAGGATACTTTAATTTCA
GATAGTTTTGTAATTACCAAGCAAAATGGAAATTATTATATCGTCTATCCCGATATGATAACATATTTGCAAGGCTCTGG
GAGGGCAAGCAGACTTTACAATGGTGGATTGACTCTTGGATTTTCAATAATTCTAGTAGATGATAGACACATCTTTGAAA
TATTGGAGAAGAAAATGCAAAAATTGTTTCCTAACACTACCTTTACTTCATTATCTAATACAAATTTATCTGAAATAAAA
ATTAAACTGGAAGACTCTAGAAAAGAAGAAGGGAATAGGGTCCATTTTAACATATCAACTGGTTTACTTATAGTAGAGTC
TCCAACAAAAGCAAAGACTATAGCTAAAATGTTTAGCAGACCCTCGGTTAGGATAAGAAATAAAGTACCAGTATACGAAA
CCATTATAGTAGATGGTAATCAAATATACGTGTTAGATATAGTAGCTTCAAAAGGCCATATCGTGGATCTAACCTTAGAA
GATATAGGATATTATGGGATAAAAGTAGAAGATGATGGAACTATAAAGCCATATTACGACTTAATAAAGAAATGCCTCGA
CTGTAATAAGATATTTTCTAGTGCTTCAGATAAATGTCCATACTGTGGTTCTGCAAATCTTCAATCAGCTCAAACTACCA
TTAACTTACTCAGGGAGTTAGCGTTATCAGTAGATAAAGTGTTTATAGCTTCTGACCCAGATACTGAAGGGGAGAAGATA
GCATATGATCTGGCTTCATTCTTGTCTCCATATAATTCCAACGTGTATAGAGTAGTATATCACGAAATTACTAAGAAGGC
AATATTAGAGGCATTGAGGAATCCCAAAAAGATTAATACAAATCTAGTAATGAGTCAGATAGTTAGAAGGATAGAAGATA
GATGGATTGGCTTCACGTTAAGTAACTTACTAAAAACGAAGTTTAATGGACATAATCATGGTGCGGGTAGGGTACAAACT
CCAGTTTTAGGTTGGATAGTGAATAAAACGATAAAGTATAAGAGTGCAATGGGTCACGTGGTTTATATTGACATCGCGGG
ATACTCCATTAAAAAATATTTTAGTGAAAAAAGGAAGGTGGAAGAGTATATAAATAACTTACAAGTAGCTAGAATTGAAA
AAATCTCTGAAGAGAAAATACTATTATCTCCATTACCTCCCTTTACTACAGACACCTTACTTATTGAGGCTAACATGAAA
TATAAACTACCAGCTAATCTTGTAATGAAGATTGCTCAAGATCTATTTGAGGCTGGCCTAATAACATATCATAGAACTGA
TAGTACTCATATTTCCTCTGTAGGTATAGAAATAGCAAAGGAGTATCTTCAAAAGCAAGCGCTCATTAAAGAGTTTGTTC
CTAGATCATGGGAATCATCGGAGGAAGGTGCTCATGAGGCAATAAGACCAACTAGAGCTATAGACGTTAACGAGTTAATT
CAAGAAATAGAGGAGAATCCTTATAAGTATTCGATAAGGTTTAGTAAATTACACTTATTAATTTACGACTTAATATTCAA
GCGATTTATAGCTAGTCAGATGTCCCATGCAGTTGGTACAAAAAGTAGGTATTTGATAAAGTTAGGCAAGGACGATAATG
TCGATGTAGAATTGTTAAGTAATGCTGAAGGCGGATTTATTAAGGTATATCCAGTTAAGGTGTATAATTTACCTGTAGGT
GAGATTCAACCTAAAGTTAATATTACTAAGGGGTCAAGTGAACAATTGCTAAGTTACTCTGATGTGATATCATTAATGAA
ATCTAAGGGAATTGGAAGGCCTAGTACATATGCAAAAACTATAGAAAATCTAATGAAGCATGGATATATAGTTAGCAGTA
AAAGAAAGTCATATCTAATAGCAACAAACAGAGGTATCTCAGTATATCAATTTCTAAGCTCCAAATTCTACGATCTAGTT
TCCGAAAGTACCACATCTAGATTAATGACAAAATTGGACGACATTGCACTAAGCAAGTTGAATGCTTCTACAGTGTTATT
AGAAATATTCAGCGAGATATCTACCTTAGTAAACCCTCTTAAGTCTGAGCAAAATGTATGA

Upstream 100 bases:

>100_bases
TCAAATAGACATTCATATAAAGCTAAAAAAGTTAACCGAATAGAGTAACACTTCGATAACTCTTTTAAAAGATCTTACCA
TCATAAAGTTTTTTCTAGCT

Downstream 100 bases:

>100_bases
TATACGCCTTCTATCTCTAACTTCACTTCCAGTCTGCACATTTACCAATTGTACGCCATCTCCTAATCTGTCCTTTAATG
AATTGTAGACGTCTACTGCT

Product: reverse gyrase

Products: NA

Alternate protein names: Helicase; Topoisomerase

Number of amino acids: Translated: 1166; Mature: 1166

Protein sequence:

>1166_residues
MINVMYKNSCPNCGGDISGDRLLNGLPCEACLPYINGIDDVDHISKVKTLYNILLNNDKIKNYWNLYYNITTFETVFKYF
RDKTGYEPWSLQKLWLRRLASNQSFTMSAPTGLGKTTTLMTYSVFIGQDVVYIVPTKSLMEQVCKRLEKLGAQVSCGKID
QKKVSVITISYLNKNADSIVSLKPNFVVIDDADAVIKSGKTTDRLVSLLGIPKDVYESAIQLIRLRNKYYFSNEYTEEVK
EKIRELELKIAEFKDKISQLVIASATIRPKGIKQKALRLLTGFEPSSIQLYARNIIDAYTENLDLSIVKELGSGGLILVS
KEYGRSKLNEIKKYVEDLGFNAKLAISGRKFLDDFSQGKVDILVGSASYYGVAVRGIDEPKRLKYVIYYGVPKIRAKLFD
ALSNPFTLLRVGKLIGIDFSKLQNKILILNPSEVQLLKFSIIKGESINYHKLEQLRQELLYYMSLVKDKLKEKVEDTLIS
DSFVITKQNGNYYIVYPDMITYLQGSGRASRLYNGGLTLGFSIILVDDRHIFEILEKKMQKLFPNTTFTSLSNTNLSEIK
IKLEDSRKEEGNRVHFNISTGLLIVESPTKAKTIAKMFSRPSVRIRNKVPVYETIIVDGNQIYVLDIVASKGHIVDLTLE
DIGYYGIKVEDDGTIKPYYDLIKKCLDCNKIFSSASDKCPYCGSANLQSAQTTINLLRELALSVDKVFIASDPDTEGEKI
AYDLASFLSPYNSNVYRVVYHEITKKAILEALRNPKKINTNLVMSQIVRRIEDRWIGFTLSNLLKTKFNGHNHGAGRVQT
PVLGWIVNKTIKYKSAMGHVVYIDIAGYSIKKYFSEKRKVEEYINNLQVARIEKISEEKILLSPLPPFTTDTLLIEANMK
YKLPANLVMKIAQDLFEAGLITYHRTDSTHISSVGIEIAKEYLQKQALIKEFVPRSWESSEEGAHEAIRPTRAIDVNELI
QEIEENPYKYSIRFSKLHLLIYDLIFKRFIASQMSHAVGTKSRYLIKLGKDDNVDVELLSNAEGGFIKVYPVKVYNLPVG
EIQPKVNITKGSSEQLLSYSDVISLMKSKGIGRPSTYAKTIENLMKHGYIVSSKRKSYLIATNRGISVYQFLSSKFYDLV
SESTTSRLMTKLDDIALSKLNASTVLLEIFSEISTLVNPLKSEQNV

Sequences:

>Translated_1166_residues
MINVMYKNSCPNCGGDISGDRLLNGLPCEACLPYINGIDDVDHISKVKTLYNILLNNDKIKNYWNLYYNITTFETVFKYF
RDKTGYEPWSLQKLWLRRLASNQSFTMSAPTGLGKTTTLMTYSVFIGQDVVYIVPTKSLMEQVCKRLEKLGAQVSCGKID
QKKVSVITISYLNKNADSIVSLKPNFVVIDDADAVIKSGKTTDRLVSLLGIPKDVYESAIQLIRLRNKYYFSNEYTEEVK
EKIRELELKIAEFKDKISQLVIASATIRPKGIKQKALRLLTGFEPSSIQLYARNIIDAYTENLDLSIVKELGSGGLILVS
KEYGRSKLNEIKKYVEDLGFNAKLAISGRKFLDDFSQGKVDILVGSASYYGVAVRGIDEPKRLKYVIYYGVPKIRAKLFD
ALSNPFTLLRVGKLIGIDFSKLQNKILILNPSEVQLLKFSIIKGESINYHKLEQLRQELLYYMSLVKDKLKEKVEDTLIS
DSFVITKQNGNYYIVYPDMITYLQGSGRASRLYNGGLTLGFSIILVDDRHIFEILEKKMQKLFPNTTFTSLSNTNLSEIK
IKLEDSRKEEGNRVHFNISTGLLIVESPTKAKTIAKMFSRPSVRIRNKVPVYETIIVDGNQIYVLDIVASKGHIVDLTLE
DIGYYGIKVEDDGTIKPYYDLIKKCLDCNKIFSSASDKCPYCGSANLQSAQTTINLLRELALSVDKVFIASDPDTEGEKI
AYDLASFLSPYNSNVYRVVYHEITKKAILEALRNPKKINTNLVMSQIVRRIEDRWIGFTLSNLLKTKFNGHNHGAGRVQT
PVLGWIVNKTIKYKSAMGHVVYIDIAGYSIKKYFSEKRKVEEYINNLQVARIEKISEEKILLSPLPPFTTDTLLIEANMK
YKLPANLVMKIAQDLFEAGLITYHRTDSTHISSVGIEIAKEYLQKQALIKEFVPRSWESSEEGAHEAIRPTRAIDVNELI
QEIEENPYKYSIRFSKLHLLIYDLIFKRFIASQMSHAVGTKSRYLIKLGKDDNVDVELLSNAEGGFIKVYPVKVYNLPVG
EIQPKVNITKGSSEQLLSYSDVISLMKSKGIGRPSTYAKTIENLMKHGYIVSSKRKSYLIATNRGISVYQFLSSKFYDLV
SESTTSRLMTKLDDIALSKLNASTVLLEIFSEISTLVNPLKSEQNV
>Mature_1166_residues
MINVMYKNSCPNCGGDISGDRLLNGLPCEACLPYINGIDDVDHISKVKTLYNILLNNDKIKNYWNLYYNITTFETVFKYF
RDKTGYEPWSLQKLWLRRLASNQSFTMSAPTGLGKTTTLMTYSVFIGQDVVYIVPTKSLMEQVCKRLEKLGAQVSCGKID
QKKVSVITISYLNKNADSIVSLKPNFVVIDDADAVIKSGKTTDRLVSLLGIPKDVYESAIQLIRLRNKYYFSNEYTEEVK
EKIRELELKIAEFKDKISQLVIASATIRPKGIKQKALRLLTGFEPSSIQLYARNIIDAYTENLDLSIVKELGSGGLILVS
KEYGRSKLNEIKKYVEDLGFNAKLAISGRKFLDDFSQGKVDILVGSASYYGVAVRGIDEPKRLKYVIYYGVPKIRAKLFD
ALSNPFTLLRVGKLIGIDFSKLQNKILILNPSEVQLLKFSIIKGESINYHKLEQLRQELLYYMSLVKDKLKEKVEDTLIS
DSFVITKQNGNYYIVYPDMITYLQGSGRASRLYNGGLTLGFSIILVDDRHIFEILEKKMQKLFPNTTFTSLSNTNLSEIK
IKLEDSRKEEGNRVHFNISTGLLIVESPTKAKTIAKMFSRPSVRIRNKVPVYETIIVDGNQIYVLDIVASKGHIVDLTLE
DIGYYGIKVEDDGTIKPYYDLIKKCLDCNKIFSSASDKCPYCGSANLQSAQTTINLLRELALSVDKVFIASDPDTEGEKI
AYDLASFLSPYNSNVYRVVYHEITKKAILEALRNPKKINTNLVMSQIVRRIEDRWIGFTLSNLLKTKFNGHNHGAGRVQT
PVLGWIVNKTIKYKSAMGHVVYIDIAGYSIKKYFSEKRKVEEYINNLQVARIEKISEEKILLSPLPPFTTDTLLIEANMK
YKLPANLVMKIAQDLFEAGLITYHRTDSTHISSVGIEIAKEYLQKQALIKEFVPRSWESSEEGAHEAIRPTRAIDVNELI
QEIEENPYKYSIRFSKLHLLIYDLIFKRFIASQMSHAVGTKSRYLIKLGKDDNVDVELLSNAEGGFIKVYPVKVYNLPVG
EIQPKVNITKGSSEQLLSYSDVISLMKSKGIGRPSTYAKTIENLMKHGYIVSSKRKSYLIATNRGISVYQFLSSKFYDLV
SESTTSRLMTKLDDIALSKLNASTVLLEIFSEISTLVNPLKSEQNV

Specific function: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DN

COG id: COG1110

COG function: function code L; Reverse gyrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Toprim domain

Homologues:

Organism=Escherichia coli, GI1787529, Length=627, Percent_Identity=26.9537480063796, Blast_Score=171, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RGYR2_SULSO (Q97ZF5)

Other databases:

- EMBL:   AE006641
- PIR:   F90247
- RefSeq:   NP_342447.1
- ProteinModelPortal:   Q97ZF5
- GeneID:   1455204
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0963
- NMPDR:   fig|273057.1.peg.870
- HOGENOM:   HBG312311
- OMA:   NEGTHEA
- ProtClustDB:   PRK09401
- BioCyc:   SSOL273057:SSO0963-MONOMER
- BRENDA:   5.99.1.3
- GO:   GO:0005694
- HAMAP:   MF_01125
- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR014021
- InterPro:   IPR005736
- InterPro:   IPR003601
- InterPro:   IPR013497
- InterPro:   IPR013824
- InterPro:   IPR013826
- InterPro:   IPR000380
- InterPro:   IPR003602
- InterPro:   IPR006171
- Gene3D:   G3DSA:1.10.460.10
- Gene3D:   G3DSA:1.10.290.10
- PANTHER:   PTHR11390
- PRINTS:   PR00417
- SMART:   SM00487
- SMART:   SM00437
- SMART:   SM00436
- SMART:   SM00493
- TIGRFAMs:   TIGR01054

Pfam domain/function: PF00270 DEAD; PF01131 Topoisom_bac; PF01751 Toprim; SSF56712 Topo_IA_core

EC number: =3.6.4.12; =5.99.1.3

Molecular weight: Translated: 132079; Mature: 132079

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS51192 HELICASE_ATP_BIND_1

Important sites: ACT_SITE 903-903 BINDING 92-92

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINVMYKNSCPNCGGDISGDRLLNGLPCEACLPYINGIDDVDHISKVKTLYNILLNNDKI
CEEEEEECCCCCCCCCCCHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
KNYWNLYYNITTFETVFKYFRDKTGYEPWSLQKLWLRRLASNQSFTMSAPTGLGKTTTLM
CCEEEEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHE
TYSVFIGQDVVYIVPTKSLMEQVCKRLEKLGAQVSCGKIDQKKVSVITISYLNKNADSIV
EEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCCEE
SLKPNFVVIDDADAVIKSGKTTDRLVSLLGIPKDVYESAIQLIRLRNKYYFSNEYTEEVK
EECCCEEEEECCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCEEECCHHHHHHH
EKIRELELKIAEFKDKISQLVIASATIRPKGIKQKALRLLTGFEPSSIQLYARNIIDAYT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ENLDLSIVKELGSGGLILVSKEYGRSKLNEIKKYVEDLGFNAKLAISGRKFLDDFSQGKV
CCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCE
DILVGSASYYGVAVRGIDEPKRLKYVIYYGVPKIRAKLFDALSNPFTLLRVGKLIGIDFS
EEEEECCCEEEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHCCCHH
KLQNKILILNPSEVQLLKFSIIKGESINYHKLEQLRQELLYYMSLVKDKLKEKVEDTLIS
HHCCEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSFVITKQNGNYYIVYPDMITYLQGSGRASRLYNGGLTLGFSIILVDDRHIFEILEKKMQ
CCEEEEEECCCEEEECCCHHHHHCCCCCCCCEECCCEEEEEEEEEECCHHHHHHHHHHHH
KLFPNTTFTSLSNTNLSEIKIKLEDSRKEEGNRVHFNISTGLLIVESPTKAKTIAKMFSR
HHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCEEEEECCCHHHHHHHHHCC
PSVRIRNKVPVYETIIVDGNQIYVLDIVASKGHIVDLTLEDIGYYGIKVEDDGTIKPYYD
CCEEECCCCCEEEEEEEECCEEEEEEEEECCCCEEEEEEHHCCEEEEEECCCCCCCHHHH
LIKKCLDCNKIFSSASDKCPYCGSANLQSAQTTINLLRELALSVDKVFIASDPDTEGEKI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHH
AYDLASFLSPYNSNVYRVVYHEITKKAILEALRNPKKINTNLVMSQIVRRIEDRWIGFTL
HHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SNLLKTKFNGHNHGAGRVQTPVLGWIVNKTIKYKSAMGHVVYIDIAGYSIKKYFSEKRKV
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
EEYINNLQVARIEKISEEKILLSPLPPFTTDTLLIEANMKYKLPANLVMKIAQDLFEAGL
HHHHCCCCHHHHHHCCCCCEEECCCCCCCCCEEEEEECCCEECCHHHHHHHHHHHHHCCC
ITYHRTDSTHISSVGIEIAKEYLQKQALIKEFVPRSWESSEEGAHEAIRPTRAIDVNELI
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCHHHHH
QEIEENPYKYSIRFSKLHLLIYDLIFKRFIASQMSHAVGTKSRYLIKLGKDDNVDVELLS
HHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEE
NAEGGFIKVYPVKVYNLPVGEIQPKVNITKGSSEQLLSYSDVISLMKSKGIGRPSTYAKT
CCCCCEEEEEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IENLMKHGYIVSSKRKSYLIATNRGISVYQFLSSKFYDLVSESTTSRLMTKLDDIALSKL
HHHHHHCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NASTVLLEIFSEISTLVNPLKSEQNV
CHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MINVMYKNSCPNCGGDISGDRLLNGLPCEACLPYINGIDDVDHISKVKTLYNILLNNDKI
CEEEEEECCCCCCCCCCCHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
KNYWNLYYNITTFETVFKYFRDKTGYEPWSLQKLWLRRLASNQSFTMSAPTGLGKTTTLM
CCEEEEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHE
TYSVFIGQDVVYIVPTKSLMEQVCKRLEKLGAQVSCGKIDQKKVSVITISYLNKNADSIV
EEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCCEE
SLKPNFVVIDDADAVIKSGKTTDRLVSLLGIPKDVYESAIQLIRLRNKYYFSNEYTEEVK
EECCCEEEEECCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCEEECCHHHHHHH
EKIRELELKIAEFKDKISQLVIASATIRPKGIKQKALRLLTGFEPSSIQLYARNIIDAYT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ENLDLSIVKELGSGGLILVSKEYGRSKLNEIKKYVEDLGFNAKLAISGRKFLDDFSQGKV
CCCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCE
DILVGSASYYGVAVRGIDEPKRLKYVIYYGVPKIRAKLFDALSNPFTLLRVGKLIGIDFS
EEEEECCCEEEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHCCCHH
KLQNKILILNPSEVQLLKFSIIKGESINYHKLEQLRQELLYYMSLVKDKLKEKVEDTLIS
HHCCEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSFVITKQNGNYYIVYPDMITYLQGSGRASRLYNGGLTLGFSIILVDDRHIFEILEKKMQ
CCEEEEEECCCEEEECCCHHHHHCCCCCCCCEECCCEEEEEEEEEECCHHHHHHHHHHHH
KLFPNTTFTSLSNTNLSEIKIKLEDSRKEEGNRVHFNISTGLLIVESPTKAKTIAKMFSR
HHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCEEEEECCCHHHHHHHHHCC
PSVRIRNKVPVYETIIVDGNQIYVLDIVASKGHIVDLTLEDIGYYGIKVEDDGTIKPYYD
CCEEECCCCCEEEEEEEECCEEEEEEEEECCCCEEEEEEHHCCEEEEEECCCCCCCHHHH
LIKKCLDCNKIFSSASDKCPYCGSANLQSAQTTINLLRELALSVDKVFIASDPDTEGEKI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHH
AYDLASFLSPYNSNVYRVVYHEITKKAILEALRNPKKINTNLVMSQIVRRIEDRWIGFTL
HHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SNLLKTKFNGHNHGAGRVQTPVLGWIVNKTIKYKSAMGHVVYIDIAGYSIKKYFSEKRKV
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
EEYINNLQVARIEKISEEKILLSPLPPFTTDTLLIEANMKYKLPANLVMKIAQDLFEAGL
HHHHCCCCHHHHHHCCCCCEEECCCCCCCCCEEEEEECCCEECCHHHHHHHHHHHHHCCC
ITYHRTDSTHISSVGIEIAKEYLQKQALIKEFVPRSWESSEEGAHEAIRPTRAIDVNELI
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCHHHHH
QEIEENPYKYSIRFSKLHLLIYDLIFKRFIASQMSHAVGTKSRYLIKLGKDDNVDVELLS
HHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEE
NAEGGFIKVYPVKVYNLPVGEIQPKVNITKGSSEQLLSYSDVISLMKSKGIGRPSTYAKT
CCCCCEEEEEEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IENLMKHGYIVSSKRKSYLIATNRGISVYQFLSSKFYDLVSESTTSRLMTKLDDIALSKL
HHHHHHCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NASTVLLEIFSEISTLVNPLKSEQNV
CHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726