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The map label for this gene is psmB1 [H]

Identifier: 15897221

GI number: 15897221

Start: 236451

End: 237041

Strand: Reverse

Name: psmB1 [H]

Synonym: SSO0278

Alternate gene names: 15897221

Gene position: 237041-236451 (Counterclockwise)

Preceding gene: 15897222

Following gene: 15897219

Centisome position: 7.92

GC content: 35.7

Gene sequence:

>591_bases
ATGGAAGAATTACCTGCAACTGCTGTTGGTTTGAAGGTAAATGATGGAATCGTATTAGCTTCTGAGAGACGATTAAGCTA
TGGTGGTTACGTACTAAGTAAACAAGCAAAAAAAGTATATAAAATAAATAAATTCCTCATGGCAGGGGCTGGAATATATG
GCGATTTGCAGACTTTGACACGAATAATGAATGTAGAAATAAAGTACTATGAGGTTTCAACTGGTAAACCAATCTCTGTT
CATGCTGCAGCTAAATTACTTTCGGTAATACTATACCAGTATAAAGTGATGCCTTTCATTTCAGAAATTCTATTTGGAGG
AGTCGATGAAAAGGGTCCACAACTTTATGTGTTAGACCCTATAGGCTCGTTAATTGAAGATAATTACGCTGCTGTAGGAT
CAGGAGCCAGGATAGCAATAGGAGTTCTTGAATCTGAATATGATCCCAATATGAGTTTAGATGTAGCAACACAATTAATA
ACAAAGGCGATAAAAGCATCAATAGAACGTGATATCACATCTGGAGATGGGATAGATTTAGCTATAATAGATAAGAAAGG
GAACTACGAAAATAAATTCATCCCATACTAA

Upstream 100 bases:

>100_bases
ATTACACGAAAACAGATTTCTATCCCACTAGAGAACGTTCTAGATGCAATAAAACAAACGTTATAAATGGCATTTATAAG
TATATTATGGGTAAACTAGC

Downstream 100 bases:

>100_bases
TTGTTTTTCTTCACGCAAAAGTAAACATGATCCATGATATTTAGCTGAGATGTTCTAAGGAAGCTTTCTTTATTACTTAT
TATCTTTACTAGAAGACCAT

Product: proteasome subunit

Products: NA

Alternate protein names: 20S proteasome beta subunit 1; Proteasome core protein PsmB 1 [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MEELPATAVGLKVNDGIVLASERRLSYGGYVLSKQAKKVYKINKFLMAGAGIYGDLQTLTRIMNVEIKYYEVSTGKPISV
HAAAKLLSVILYQYKVMPFISEILFGGVDEKGPQLYVLDPIGSLIEDNYAAVGSGARIAIGVLESEYDPNMSLDVATQLI
TKAIKASIERDITSGDGIDLAIIDKKGNYENKFIPY

Sequences:

>Translated_196_residues
MEELPATAVGLKVNDGIVLASERRLSYGGYVLSKQAKKVYKINKFLMAGAGIYGDLQTLTRIMNVEIKYYEVSTGKPISV
HAAAKLLSVILYQYKVMPFISEILFGGVDEKGPQLYVLDPIGSLIEDNYAAVGSGARIAIGVLESEYDPNMSLDVATQLI
TKAIKASIERDITSGDGIDLAIIDKKGNYENKFIPY
>Mature_196_residues
MEELPATAVGLKVNDGIVLASERRLSYGGYVLSKQAKKVYKINKFLMAGAGIYGDLQTLTRIMNVEIKYYEVSTGKPISV
HAAAKLLSVILYQYKVMPFISEILFGGVDEKGPQLYVLDPIGSLIEDNYAAVGSGARIAIGVLESEYDPNMSLDVATQLI
TKAIKASIERDITSGDGIDLAIIDKKGNYENKFIPY

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation [H]

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family [H]

Homologues:

Organism=Homo sapiens, GI4506191, Length=182, Percent_Identity=34.0659340659341, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI73747875, Length=182, Percent_Identity=34.0659340659341, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI4758970, Length=182, Percent_Identity=34.0659340659341, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI4506201, Length=182, Percent_Identity=32.967032967033, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI4506193, Length=193, Percent_Identity=31.6062176165803, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI4506203, Length=181, Percent_Identity=33.7016574585635, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI153791216, Length=182, Percent_Identity=30.2197802197802, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI22538465, Length=181, Percent_Identity=26.5193370165746, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI23110942, Length=196, Percent_Identity=27.0408163265306, Blast_Score=80, Evalue=9e-16,
Organism=Homo sapiens, GI195539356, Length=138, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI23110925, Length=183, Percent_Identity=25.1366120218579, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI222144262, Length=117, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508495, Length=180, Percent_Identity=30.5555555555556, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17541700, Length=191, Percent_Identity=27.2251308900524, Blast_Score=93, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17508499, Length=169, Percent_Identity=34.3195266272189, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17554384, Length=191, Percent_Identity=27.2251308900524, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17535357, Length=174, Percent_Identity=25.8620689655172, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508493, Length=183, Percent_Identity=22.9508196721311, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6325360, Length=183, Percent_Identity=32.2404371584699, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324731, Length=179, Percent_Identity=30.1675977653631, Blast_Score=92, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6321574, Length=199, Percent_Identity=28.1407035175879, Blast_Score=72, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319430, Length=202, Percent_Identity=24.2574257425743, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320849, Length=184, Percent_Identity=25.5434782608696, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322459, Length=194, Percent_Identity=23.7113402061856, Blast_Score=62, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24639979, Length=180, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21355573, Length=182, Percent_Identity=34.0659340659341, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24652553, Length=182, Percent_Identity=34.0659340659341, Blast_Score=100, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24664391, Length=183, Percent_Identity=31.1475409836066, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI28573221, Length=179, Percent_Identity=25.1396648044693, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20130281, Length=182, Percent_Identity=28.021978021978, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24584895, Length=186, Percent_Identity=31.1827956989247, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17737605, Length=192, Percent_Identity=28.6458333333333, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24653999, Length=183, Percent_Identity=27.3224043715847, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654391, Length=186, Percent_Identity=26.8817204301075, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24654389, Length=186, Percent_Identity=26.8817204301075, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24581176, Length=185, Percent_Identity=26.4864864864865, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21355629, Length=183, Percent_Identity=24.0437158469945, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019983
- InterPro:   IPR000243
- InterPro:   IPR016050
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: =3.4.25.1 [H]

Molecular weight: Translated: 21376; Mature: 21376

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00854 PROTEASOME_B

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEELPATAVGLKVNDGIVLASERRLSYGGYVLSKQAKKVYKINKFLMAGAGIYGDLQTLT
CCCCCCEEEEEEECCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHH
RIMNVEIKYYEVSTGKPISVHAAAKLLSVILYQYKVMPFISEILFGGVDEKGPQLYVLDP
HHHCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
IGSLIEDNYAAVGSGARIAIGVLESEYDPNMSLDVATQLITKAIKASIERDITSGDGIDL
HHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEE
AIIDKKGNYENKFIPY
EEEECCCCCCCCCCCC
>Mature Secondary Structure
MEELPATAVGLKVNDGIVLASERRLSYGGYVLSKQAKKVYKINKFLMAGAGIYGDLQTLT
CCCCCCEEEEEEECCCEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHH
RIMNVEIKYYEVSTGKPISVHAAAKLLSVILYQYKVMPFISEILFGGVDEKGPQLYVLDP
HHHCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECC
IGSLIEDNYAAVGSGARIAIGVLESEYDPNMSLDVATQLITKAIKASIERDITSGDGIDL
HHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEE
AIIDKKGNYENKFIPY
EEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA