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The map label for this gene is pheT

Identifier: 15897062

GI number: 15897062

Start: 82518

End: 84152

Strand: Direct

Name: pheT

Synonym: SSO0101

Alternate gene names: 15897062

Gene position: 82518-84152 (Clockwise)

Preceding gene: 15897061

Following gene: 15897063

Centisome position: 2.76

GC content: 32.54

Gene sequence:

>1635_bases
ATGGTAACTATAGTATTAAATAAATATAAATTATTAAATAAAATAGGCATAGGTCAACAGAAACTAGAGGATTTATTGTT
TAACTTAAAATCAGAGATAAAACCAGTTGACGAAAGTAATATTGAAATAGAGATAAATGCTGACCGATTAGATCTACTCT
CCTCTGATGGGATAGCTAGAGCGATTAAAGGCTTGTTAGAAAAAGAGCTAGGCGAAGCAAAGTATGATATTACGGATACT
GAATATAAGTTAATAGTTGATAATGTAAGAACGAGACCTTACGCGTTGGCTGCTGTAATCTATAATGCTAAAATAGACCT
TCAAGAACTAATACAGTTTCAAGAAAAACTTCATAGTACCATAGGGAGAAAGAGAAAAAAGGTAGCTATAGGCATTCACG
ATCTAAAGAAAATAGATTCAAAGAGGATAGAATATAGGGAAGTTCCTCTTTCCTATAAATTTATTCCATTATATGAAAAG
GAAGAACTTACAATTAGCGAGGTCTTGGAAAAGACTGAGCAGGGGAAACTTTATGGAAATATTTCGATATCTAATGGAGT
ATCACCAGCAATAGTTCAAGAAGATGGAGAAGTACTAAGCATACCTCCAATAATCAACTCTGATAAGACAAAATTGGACG
AGAGCACAAAAGATCTCTTCATCGACGTTACTGGAACTTCCTTTGAAGCAGTTGCGCAAACCCTAGATATAATAGTTTCA
AATCTAGCAGAAGCTGGAGGGACGATAGGAAGAGTAAAAGTAATAAAAACTGATAATTCCTTCCAACAATCTTCGCCCTT
ACTCATACATAAAATTCAGAATGTTAGAGAGGAATATGCAAATAAAATTTTAGGAATCAAAATCAGTGAAGAAGAGATAT
GTAAACATATAACGAGAATGAGAATGAATTGTAACGTAGAAAATGGAATCATAAGAGTTACAGTACCTCAATATAGGGTA
GATATAATAAATGAAATCGATATAGTAGAGGATATTGCAATGAGTATTGGATATAATAATCTAGAACCCTCTAAGTATAT
TTCGACAAACTATGGTTCTTATGATTACTTAACATTACTGGAAAGGAAAATGAGGGAATTAAGCATCGGAGCAGGGTTTG
TAGAGGTATTTAACTTTGTGCTAATTAAAAATGAAAAGATACTTGATAGTAAGTATGTGAAAATTCTCAACCCTATTTCT
GAGGAATATAATGCAGTAAGGAATTCGCTAATTCCAATATTATTAGATTTTCTATCTAAAAATCAGCATGCGAAATTCCC
AATTAGAATTTTTGAGACCGGAGACGTGGTAATTTATGATTCTTCGACAGATACTGGATTTAGAAATGATAAAAGGGCTG
CATATGCAATAATGGACAATAAGGTAAGTTATGAAGACGTGCAAGCACCTATCCATTACATTTTGAAAACATTAGGCATA
GAAGTAAATTATAAGGAAGAAAATAATGACATTTTCATTGAAGGACGTTCAGCATCAATAGTGTATGAAAACGAGAAAAT
AGGGGTAATAGGTGAAATTAATCCTGACGTATTAATAAGATTTGGTATTGAATATCCTACAGTAATCGCCGAACTGTATA
TCACGGAGATAGCTAAAAAACTTAACAAGAGATAA

Upstream 100 bases:

>100_bases
GACTTGCTATGAGCTTTCTCAATATTAGTGATATTAGATTACTATATTCTAACAATATAGAGTATATAAGAGATACTAAA
GTGAAAATAGAGTGATATAA

Downstream 100 bases:

>100_bases
TAATATAGGAGGTGGTGTCAAATTCCATTCATAATAACAGATGATATTCGTCTATACTATGAAATAAGAGGGCATGGAAA
GCCTATTGTGCTAATTCACC

Product: phenylalanyl-tRNA synthetase subunit beta

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase beta chain; PheRS

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MVTIVLNKYKLLNKIGIGQQKLEDLLFNLKSEIKPVDESNIEIEINADRLDLLSSDGIARAIKGLLEKELGEAKYDITDT
EYKLIVDNVRTRPYALAAVIYNAKIDLQELIQFQEKLHSTIGRKRKKVAIGIHDLKKIDSKRIEYREVPLSYKFIPLYEK
EELTISEVLEKTEQGKLYGNISISNGVSPAIVQEDGEVLSIPPIINSDKTKLDESTKDLFIDVTGTSFEAVAQTLDIIVS
NLAEAGGTIGRVKVIKTDNSFQQSSPLLIHKIQNVREEYANKILGIKISEEEICKHITRMRMNCNVENGIIRVTVPQYRV
DIINEIDIVEDIAMSIGYNNLEPSKYISTNYGSYDYLTLLERKMRELSIGAGFVEVFNFVLIKNEKILDSKYVKILNPIS
EEYNAVRNSLIPILLDFLSKNQHAKFPIRIFETGDVVIYDSSTDTGFRNDKRAAYAIMDNKVSYEDVQAPIHYILKTLGI
EVNYKEENNDIFIEGRSASIVYENEKIGVIGEINPDVLIRFGIEYPTVIAELYITEIAKKLNKR

Sequences:

>Translated_544_residues
MVTIVLNKYKLLNKIGIGQQKLEDLLFNLKSEIKPVDESNIEIEINADRLDLLSSDGIARAIKGLLEKELGEAKYDITDT
EYKLIVDNVRTRPYALAAVIYNAKIDLQELIQFQEKLHSTIGRKRKKVAIGIHDLKKIDSKRIEYREVPLSYKFIPLYEK
EELTISEVLEKTEQGKLYGNISISNGVSPAIVQEDGEVLSIPPIINSDKTKLDESTKDLFIDVTGTSFEAVAQTLDIIVS
NLAEAGGTIGRVKVIKTDNSFQQSSPLLIHKIQNVREEYANKILGIKISEEEICKHITRMRMNCNVENGIIRVTVPQYRV
DIINEIDIVEDIAMSIGYNNLEPSKYISTNYGSYDYLTLLERKMRELSIGAGFVEVFNFVLIKNEKILDSKYVKILNPIS
EEYNAVRNSLIPILLDFLSKNQHAKFPIRIFETGDVVIYDSSTDTGFRNDKRAAYAIMDNKVSYEDVQAPIHYILKTLGI
EVNYKEENNDIFIEGRSASIVYENEKIGVIGEINPDVLIRFGIEYPTVIAELYITEIAKKLNKR
>Mature_544_residues
MVTIVLNKYKLLNKIGIGQQKLEDLLFNLKSEIKPVDESNIEIEINADRLDLLSSDGIARAIKGLLEKELGEAKYDITDT
EYKLIVDNVRTRPYALAAVIYNAKIDLQELIQFQEKLHSTIGRKRKKVAIGIHDLKKIDSKRIEYREVPLSYKFIPLYEK
EELTISEVLEKTEQGKLYGNISISNGVSPAIVQEDGEVLSIPPIINSDKTKLDESTKDLFIDVTGTSFEAVAQTLDIIVS
NLAEAGGTIGRVKVIKTDNSFQQSSPLLIHKIQNVREEYANKILGIKISEEEICKHITRMRMNCNVENGIIRVTVPQYRV
DIINEIDIVEDIAMSIGYNNLEPSKYISTNYGSYDYLTLLERKMRELSIGAGFVEVFNFVLIKNEKILDSKYVKILNPIS
EEYNAVRNSLIPILLDFLSKNQHAKFPIRIFETGDVVIYDSSTDTGFRNDKRAAYAIMDNKVSYEDVQAPIHYILKTLGI
EVNYKEENNDIFIEGRSASIVYENEKIGVIGEINPDVLIRFGIEYPTVIAELYITEIAKKLNKR

Specific function: Unknown

COG id: COG0072

COG function: function code J; Phenylalanyl-tRNA synthetase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B5 domain

Homologues:

Organism=Homo sapiens, GI124028525, Length=519, Percent_Identity=32.1772639691715, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI24308207, Length=173, Percent_Identity=31.7919075144509, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1788006, Length=319, Percent_Identity=26.6457680250784, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17533403, Length=530, Percent_Identity=31.5094339622642, Blast_Score=231, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6323089, Length=591, Percent_Identity=28.087986463621, Blast_Score=211, Evalue=2e-55,
Organism=Drosophila melanogaster, GI21355211, Length=524, Percent_Identity=31.2977099236641, Blast_Score=220, Evalue=2e-57,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYFB_SULSO (P95960)

Other databases:

- EMBL:   Y08257
- EMBL:   AE006641
- PIR:   S75388
- RefSeq:   NP_341667.1
- ProteinModelPortal:   P95960
- SMR:   P95960
- GeneID:   1453285
- GenomeReviews:   AE006641_GR
- KEGG:   sso:SSO0101
- NMPDR:   fig|273057.1.peg.90
- HOGENOM:   HBG497667
- OMA:   LLTRMCL
- PhylomeDB:   P95960
- ProtClustDB:   PRK09616
- BioCyc:   SSOL273057:SSO0101-MONOMER
- BRENDA:   6.1.1.20
- GO:   GO:0005737
- HAMAP:   MF_00284
- InterPro:   IPR005146
- InterPro:   IPR005147
- InterPro:   IPR009061
- InterPro:   IPR004531
- InterPro:   IPR022918
- Gene3D:   G3DSA:3.30.56.20
- SMART:   SM00873
- SMART:   SM00874
- TIGRFAMs:   TIGR00471

Pfam domain/function: PF03483 B3_4; PF03484 B5; SSF46955 Putativ_DNA_bind

EC number: =6.1.1.20

Molecular weight: Translated: 61817; Mature: 61817

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS51483 B5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTIVLNKYKLLNKIGIGQQKLEDLLFNLKSEIKPVDESNIEIEINADRLDLLSSDGIAR
CEEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHCCCCHHH
AIKGLLEKELGEAKYDITDTEYKLIVDNVRTRPYALAAVIYNAKIDLQELIQFQEKLHST
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHH
IGRKRKKVAIGIHDLKKIDSKRIEYREVPLSYKFIPLYEKEELTISEVLEKTEQGKLYGN
HCCCCCEEEEEHHHHHHHHHHCCEEEECCCEEEEEEECCCCCCCHHHHHHHHHCCCEEEE
ISISNGVSPAIVQEDGEVLSIPPIINSDKTKLDESTKDLFIDVTGTSFEAVAQTLDIIVS
EEECCCCCCEEEECCCCEEEECCCCCCCCHHCCCCCCEEEEEECCCCHHHHHHHHHHHHH
NLAEAGGTIGRVKVIKTDNSFQQSSPLLIHKIQNVREEYANKILGIKISEEEICKHITRM
HHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHH
RMNCNVENGIIRVTVPQYRVDIINEIDIVEDIAMSIGYNNLEPSKYISTNYGSYDYLTLL
HHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHH
ERKMRELSIGAGFVEVFNFVLIKNEKILDSKYVKILNPISEEYNAVRNSLIPILLDFLSK
HHHHHHHHCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NQHAKFPIRIFETGDVVIYDSSTDTGFRNDKRAAYAIMDNKVSYEDVQAPIHYILKTLGI
CCCCCCCEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCC
EVNYKEENNDIFIEGRSASIVYENEKIGVIGEINPDVLIRFGIEYPTVIAELYITEIAKK
EEEEEECCCEEEEECCCEEEEEECCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHH
LNKR
HCCC
>Mature Secondary Structure
MVTIVLNKYKLLNKIGIGQQKLEDLLFNLKSEIKPVDESNIEIEINADRLDLLSSDGIAR
CEEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHCCCCHHH
AIKGLLEKELGEAKYDITDTEYKLIVDNVRTRPYALAAVIYNAKIDLQELIQFQEKLHST
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHH
IGRKRKKVAIGIHDLKKIDSKRIEYREVPLSYKFIPLYEKEELTISEVLEKTEQGKLYGN
HCCCCCEEEEEHHHHHHHHHHCCEEEECCCEEEEEEECCCCCCCHHHHHHHHHCCCEEEE
ISISNGVSPAIVQEDGEVLSIPPIINSDKTKLDESTKDLFIDVTGTSFEAVAQTLDIIVS
EEECCCCCCEEEECCCCEEEECCCCCCCCHHCCCCCCEEEEEECCCCHHHHHHHHHHHHH
NLAEAGGTIGRVKVIKTDNSFQQSSPLLIHKIQNVREEYANKILGIKISEEEICKHITRM
HHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHH
RMNCNVENGIIRVTVPQYRVDIINEIDIVEDIAMSIGYNNLEPSKYISTNYGSYDYLTLL
HHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHHHH
ERKMRELSIGAGFVEVFNFVLIKNEKILDSKYVKILNPISEEYNAVRNSLIPILLDFLSK
HHHHHHHHCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NQHAKFPIRIFETGDVVIYDSSTDTGFRNDKRAAYAIMDNKVSYEDVQAPIHYILKTLGI
CCCCCCCEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCC
EVNYKEENNDIFIEGRSASIVYENEKIGVIGEINPDVLIRFGIEYPTVIAELYITEIAKK
EEEEEECCCEEEEECCCEEEEEECCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHH
LNKR
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726