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The map label for this gene is mta [H]

Identifier: 15927968

GI number: 15927968

Start: 2446722

End: 2447462

Strand: Direct

Name: mta [H]

Synonym: SA2178

Alternate gene names: 15927968

Gene position: 2446722-2447462 (Clockwise)

Preceding gene: 15927967

Following gene: 15927989

Centisome position: 86.92

GC content: 27.94

Gene sequence:

>741_bases
TTGGCATACACATACACTTTAAAAGATATTATTGAAATTACAGGTGTAACTAAAAGAACTTTACATTATTACGATGAAAT
AGGATTATTAGTTCCAGATAAAAATGATAAAAATTATCGCGTTTATAAACAGCAAGACTTAGAAAAATTACAAAAGATTT
TAATACTCAAGTCTTTTGATTTTGATATCGCTAAAATAAAACAATACATTTCGTATGATAATGAACAATTGCGAAAGTTA
TTATCAGAGCAAATAAGCAAGTTAGATAAAAAGATTTCTGACTTACAATTAATTAGACGCTCTGTATGTGAATTTATTAA
AGGACTCTCTCTAATAGATACCAGCATTTTAAACAAGACACTACAGTCACAATATGATAAAGAAGCATCTATAAAATATG
GTCATACGAAAGCATATCAATCATTTATTAGACGTAAAGACAGCTTACAATCGCAGGATATCAGACATAAATTGACAACT
ATCTTCAATAAATTTAATCATATGTCTTTGAGTCATTATCCAATCCAAGATTGTAGTGATCTCGTATTTGAGTGGAAGGC
ATTTATGAACACTATCGCTGATTTTGATGATGAAACATTATGCTGTATTGCTAAAACATATGAAGATGATACGCGTTTCA
AAGATTACTTTAATTCATATGATAATCAAAATTTAGCATCATACATTTCAGAAGCTGTTAATTATTTTTTGAGCAATGTG
AATAAGAGCGACAATTTTTAA

Upstream 100 bases:

>100_bases
GCTATCACTTGGTAAAATACTTTTTACAAAAAACAAACATACCTATTGAAGTTGCTACAACACTTCCAGCACAAAAAATA
ATAAATGAGGTGACTGAATT

Downstream 100 bases:

>100_bases
TCCTCATACAGATGCTACAACACTGAATACACCAACTAAAATAATTGTTCAAAGTAGAAAACTAATCATTTATTCTCTAA
ATCAATAACTATAATAAAAG

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug transporter activation protein [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MAYTYTLKDIIEITGVTKRTLHYYDEIGLLVPDKNDKNYRVYKQQDLEKLQKILILKSFDFDIAKIKQYISYDNEQLRKL
LSEQISKLDKKISDLQLIRRSVCEFIKGLSLIDTSILNKTLQSQYDKEASIKYGHTKAYQSFIRRKDSLQSQDIRHKLTT
IFNKFNHMSLSHYPIQDCSDLVFEWKAFMNTIADFDDETLCCIAKTYEDDTRFKDYFNSYDNQNLASYISEAVNYFLSNV
NKSDNF

Sequences:

>Translated_246_residues
MAYTYTLKDIIEITGVTKRTLHYYDEIGLLVPDKNDKNYRVYKQQDLEKLQKILILKSFDFDIAKIKQYISYDNEQLRKL
LSEQISKLDKKISDLQLIRRSVCEFIKGLSLIDTSILNKTLQSQYDKEASIKYGHTKAYQSFIRRKDSLQSQDIRHKLTT
IFNKFNHMSLSHYPIQDCSDLVFEWKAFMNTIADFDDETLCCIAKTYEDDTRFKDYFNSYDNQNLASYISEAVNYFLSNV
NKSDNF
>Mature_245_residues
AYTYTLKDIIEITGVTKRTLHYYDEIGLLVPDKNDKNYRVYKQQDLEKLQKILILKSFDFDIAKIKQYISYDNEQLRKLL
SEQISKLDKKISDLQLIRRSVCEFIKGLSLIDTSILNKTLQSQYDKEASIKYGHTKAYQSFIRRKDSLQSQDIRHKLTTI
FNKFNHMSLSHYPIQDCSDLVFEWKAFMNTIADFDDETLCCIAKTYEDDTRFKDYFNSYDNQNLASYISEAVNYFLSNVN
KSDNF

Specific function: Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself, ydfK and ymfE [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR012925
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; PF07739 TipAS [H]

EC number: NA

Molecular weight: Translated: 29127; Mature: 28996

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCC
>Mature Secondary Structure 
AYTYTLKDIIEITGVTKRTLHYYDEIGLLVPDKNDKNYRVYKQQDLEKLQKILILKSFD
CEEHHHHHHHHHHCCHHHHHHHHHHCCCEECCCCCCCEEHHHHHHHHHHHHHHHHHCCC
FDIAKIKQYISYDNEQLRKLLSEQISKLDKKISDLQLIRRSVCEFIKGLSLIDTSILNKT
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQSQYDKEASIKYGHTKAYQSFIRRKDSLQSQDIRHKLTTIFNKFNHMSLSHYPIQDCSD
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LVFEWKAFMNTIADFDDETLCCIAKTYEDDTRFKDYFNSYDNQNLASYISEAVNYFLSNV
HHHHHHHHHHHHHCCCCCCEEEHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
NKSDNF
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9150240; 9384377 [H]