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The map label for this gene is acpS

Identifier: 16125805

GI number: 16125805

Start: 1722353

End: 1722754

Strand: Direct

Name: acpS

Synonym: CC_1558

Alternate gene names: 16125805

Gene position: 1722353-1722754 (Clockwise)

Preceding gene: 16125804

Following gene: 16125806

Centisome position: 42.88

GC content: 67.16

Gene sequence:

>402_bases
GTGATCATCGGCATCGGCTCGGACCTCTGCGACATCCGGCGGATCGAGAAGTCGCTGGAGCGCTTCGGCGACCGCTTTAC
CCACAAGGTCTTCACCGAGACCGAGCGCACGCGCTCTGAGCGCAAGCCTGATCGAGCCTCCAGCTACGCCAAACGGTTCG
CGGCCAAGGAAGCCTGCTCCAAGGCGCTCGGTACCGGCCTGAAGCGCGGCGTGCATCTGGCGGGCATGGGCGTGGTCAAC
CTGCCGTCGGGCCAGCCGACCATGGCGCTCACCGGCGGGGCGCTGGAGCGCCTGAAGGCGATGGTCCCGGAGGGCATGGA
GCCCGTAATCCATCTGTCGCTGACCGACGACCACCCCTACGCCCAGGCCTTCGTGATCATCGAGGCCCTGCCAAAGCGCT
GA

Upstream 100 bases:

>100_bases
ACTTCCTGATCGGTGAGGCGATCTTCGTGGGCCTGCCTGAAGCGATCCACCGCATGCGGGCCCTGATGGAGGCCGCGCGC
GTCGAACTTGAGGTCCTGGC

Downstream 100 bases:

>100_bases
AGGAGCTCCGCGTGGCCGAGTACATCCTGCTGATGCATGACGACGGCGGGGAGGAGCGGGCGGCCGACTGGGAGGCCTAT
CTGGATGGGCTGGCCGGCGC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MIIGIGSDLCDIRRIEKSLERFGDRFTHKVFTETERTRSERKPDRASSYAKRFAAKEACSKALGTGLKRGVHLAGMGVVN
LPSGQPTMALTGGALERLKAMVPEGMEPVIHLSLTDDHPYAQAFVIIEALPKR

Sequences:

>Translated_133_residues
MIIGIGSDLCDIRRIEKSLERFGDRFTHKVFTETERTRSERKPDRASSYAKRFAAKEACSKALGTGLKRGVHLAGMGVVN
LPSGQPTMALTGGALERLKAMVPEGMEPVIHLSLTDDHPYAQAFVIIEALPKR
>Mature_133_residues
MIIGIGSDLCDIRRIEKSLERFGDRFTHKVFTETERTRSERKPDRASSYAKRFAAKEACSKALGTGLKRGVHLAGMGVVN
LPSGQPTMALTGGALERLKAMVPEGMEPVIHLSLTDDHPYAQAFVIIEALPKR

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=130, Percent_Identity=37.6923076923077, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_CAUCN (B8H624)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002517000.1
- ProteinModelPortal:   B8H624
- SMR:   B8H624
- GeneID:   7331605
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_01627
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14622; Mature: 14622

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGIGSDLCDIRRIEKSLERFGDRFTHKVFTETERTRSERKPDRASSYAKRFAAKEACS
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KALGTGLKRGVHLAGMGVVNLPSGQPTMALTGGALERLKAMVPEGMEPVIHLSLTDDHPY
HHHHHHHHCCEEEECCCEEECCCCCCCEEECHHHHHHHHHHCCCCCCCEEEEEECCCCCH
AQAFVIIEALPKR
HHHHHHHHHCCCC
>Mature Secondary Structure
MIIGIGSDLCDIRRIEKSLERFGDRFTHKVFTETERTRSERKPDRASSYAKRFAAKEACS
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KALGTGLKRGVHLAGMGVVNLPSGQPTMALTGGALERLKAMVPEGMEPVIHLSLTDDHPY
HHHHHHHHCCEEEECCCEEECCCCCCCEEECHHHHHHHHHHCCCCCCCEEEEEECCCCCH
AQAFVIIEALPKR
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA