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The map label for this gene is uxaC

Identifier: 16125737

GI number: 16125737

Start: 1647500

End: 1648963

Strand: Direct

Name: uxaC

Synonym: CC_1490

Alternate gene names: 16125737

Gene position: 1647500-1648963 (Clockwise)

Preceding gene: 16125736

Following gene: 16125738

Centisome position: 41.01

GC content: 65.64

Gene sequence:

>1464_bases
ATGGCCAGGCCTCTGAGCTTTCACGAGGATCGTCTTTTCCCGTCGGATCCGGCCACCCGGTCCTACGCGCGTGGCCTTTA
TGCGCTGGTCAAGGACCTGCCGATCATCAGCCCGCACGGCCACACCGATCCGTCCTGGTTCGCGACCAACGCGCCGTTCC
AGGACGCCACGGACCTTCTGCTGGCGCCGGATCACTACCTCTTCCGCATGCTCTACAGCCAGGGCGTCAGCCTGGATGCG
CTGAAGGTTCGTTCCAAGGCCGGGGTTCCCGACACCGACCCGCGCGAGGCGTGGCGGGTGTTCGCGTCGCACTTTTATCT
CTTCCGGGGCACGCCGTCCTGGGTTTGGCTGAACCACGTGTTCAGCCAGGTGTTCGGCTTCACCGAGTTCCTCGAAGCGT
CGAATGCCGACGACTATTTCGACCGTATCACCGCCGCGCTGGCCACCGACGCCTTCCGCCCCCGCGCGTTGTTCGACCGC
TTCAATATCGAGACGCTCGCGACGACCGAAGGTCCGCACGAGAGCCTTCAGCATCACGCCGCGATCCGCGAAAGCGGCTG
GGGCGGCCATGTGATCACCGCCTATCGTCCAGATGCTGTGATCGATTTCGAAGACGAGCGGAGCCCGCGCGCCTTCGAAC
GGTTCGCCGAGACCTCCGGCCAGGACGTCTACAGCTGGAAGAGCTATCTGGAGGCGCACCGCCTGCGCCGCCAGGCCTTC
ATCGACGCCGGCGCGACCTCGTCCGACCATGGGCATCCCACTGCGGCGACCGCCGACCTCTCGGACGTCGAGGCCGAGGC
GCTGTTCAACAGCCTGGTGAAGGGGGATGTCACCCCGGAGAAGGCCGAACTCTTCCGCGCCCAGATGCTGACCGAGATGG
CCAAGATGAGCCTGGATGATGGTCTGGTCATGCAGATCCACCCCGGCTCTCACCGCAACCACAATGTTGGCCTGCTGAAC
TCGCACGGTCGCGACAAGGGCGCCGACATCCCGATGCGCACCGAGTATGTCGATGCGCTCAAGCCGCTGCTGACCCGCCT
GGGCAATGATCCGCGGCTGTCGATCATCCTGTTCACGCTGGACGAGACGACCTACAGCCGCGAGCTGGCCCCGCTGGCCG
GACACTATCCGGTGCTGAAGCTGGGTCCGTCCTGGTGGTTCCACGACAGCCCGGAAGGCATGATGCGCTTCCGCGAGCAG
GTCACCGAGACCGCCGGCTTCTACAACACCGTCGGCTTCAACGACGACACCCGCGCCTTCCTGTCGATCCCGGCCCGTCA
CGACGTGGCCCGGCGCGTCGACAGCGCGTTCCTCGCCCGCATGGTCGCCGAGCATCGGATGGATCTGGTCGAGGCCGAAG
AGCTGATCGTCGACCTGACCTACAACCTGCCCAAGAAGGCCTACAAGCTGGACCAGCGTCCGGACTGGGCCCGTCCCGCC
ACCCTGCGCGCCGCCGCAGAATAG

Upstream 100 bases:

>100_bases
CCACGCGCTGGTGCTTGCATCACGCGATGACACCGGTTACCAAGCGGACACGGGCAGCCGTCGCGAAGCTGTCAGAGCGT
AAGGGAGCAGACGCAAAGTC

Downstream 100 bases:

>100_bases
AACACCTTTTCCGGAGACTTCCCGATGTTCGCCAAGACCTATCACGCCACCCATCCGGACATGATGTTCGCGGTCAGCAA
TGACGACCTGCGCGACCGTT

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MARPLSFHEDRLFPSDPATRSYARGLYALVKDLPIISPHGHTDPSWFATNAPFQDATDLLLAPDHYLFRMLYSQGVSLDA
LKVRSKAGVPDTDPREAWRVFASHFYLFRGTPSWVWLNHVFSQVFGFTEFLEASNADDYFDRITAALATDAFRPRALFDR
FNIETLATTEGPHESLQHHAAIRESGWGGHVITAYRPDAVIDFEDERSPRAFERFAETSGQDVYSWKSYLEAHRLRRQAF
IDAGATSSDHGHPTAATADLSDVEAEALFNSLVKGDVTPEKAELFRAQMLTEMAKMSLDDGLVMQIHPGSHRNHNVGLLN
SHGRDKGADIPMRTEYVDALKPLLTRLGNDPRLSIILFTLDETTYSRELAPLAGHYPVLKLGPSWWFHDSPEGMMRFREQ
VTETAGFYNTVGFNDDTRAFLSIPARHDVARRVDSAFLARMVAEHRMDLVEAEELIVDLTYNLPKKAYKLDQRPDWARPA
TLRAAAE

Sequences:

>Translated_487_residues
MARPLSFHEDRLFPSDPATRSYARGLYALVKDLPIISPHGHTDPSWFATNAPFQDATDLLLAPDHYLFRMLYSQGVSLDA
LKVRSKAGVPDTDPREAWRVFASHFYLFRGTPSWVWLNHVFSQVFGFTEFLEASNADDYFDRITAALATDAFRPRALFDR
FNIETLATTEGPHESLQHHAAIRESGWGGHVITAYRPDAVIDFEDERSPRAFERFAETSGQDVYSWKSYLEAHRLRRQAF
IDAGATSSDHGHPTAATADLSDVEAEALFNSLVKGDVTPEKAELFRAQMLTEMAKMSLDDGLVMQIHPGSHRNHNVGLLN
SHGRDKGADIPMRTEYVDALKPLLTRLGNDPRLSIILFTLDETTYSRELAPLAGHYPVLKLGPSWWFHDSPEGMMRFREQ
VTETAGFYNTVGFNDDTRAFLSIPARHDVARRVDSAFLARMVAEHRMDLVEAEELIVDLTYNLPKKAYKLDQRPDWARPA
TLRAAAE
>Mature_486_residues
ARPLSFHEDRLFPSDPATRSYARGLYALVKDLPIISPHGHTDPSWFATNAPFQDATDLLLAPDHYLFRMLYSQGVSLDAL
KVRSKAGVPDTDPREAWRVFASHFYLFRGTPSWVWLNHVFSQVFGFTEFLEASNADDYFDRITAALATDAFRPRALFDRF
NIETLATTEGPHESLQHHAAIRESGWGGHVITAYRPDAVIDFEDERSPRAFERFAETSGQDVYSWKSYLEAHRLRRQAFI
DAGATSSDHGHPTAATADLSDVEAEALFNSLVKGDVTPEKAELFRAQMLTEMAKMSLDDGLVMQIHPGSHRNHNVGLLNS
HGRDKGADIPMRTEYVDALKPLLTRLGNDPRLSIILFTLDETTYSRELAPLAGHYPVLKLGPSWWFHDSPEGMMRFREQV
TETAGFYNTVGFNDDTRAFLSIPARHDVARRVDSAFLARMVAEHRMDLVEAEELIVDLTYNLPKKAYKLDQRPDWARPAT
LRAAAE

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family

Homologues:

Organism=Escherichia coli, GI2367192, Length=475, Percent_Identity=25.4736842105263, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXAC_CAUCN (B8H5V4)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002516930.1
- ProteinModelPortal:   B8H5V4
- SMR:   B8H5V4
- GeneID:   7333232
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_01557
- OMA:   AWAKTVP
- ProtClustDB:   PRK02925
- HAMAP:   MF_00675
- InterPro:   IPR003766

Pfam domain/function: PF02614 UxaC

EC number: =5.3.1.12

Molecular weight: Translated: 55052; Mature: 54921

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPLSFHEDRLFPSDPATRSYARGLYALVKDLPIISPHGHTDPSWFATNAPFQDATDLL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCEE
LAPDHYLFRMLYSQGVSLDALKVRSKAGVPDTDPREAWRVFASHFYLFRGTPSWVWLNHV
ECCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEECCCCHHHHHHH
FSQVFGFTEFLEASNADDYFDRITAALATDAFRPRALFDRFNIETLATTEGPHESLQHHA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCCCHHHHHHHHH
AIRESGWGGHVITAYRPDAVIDFEDERSPRAFERFAETSGQDVYSWKSYLEAHRLRRQAF
HHHCCCCCCCEEEEECCCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IDAGATSSDHGHPTAATADLSDVEAEALFNSLVKGDVTPEKAELFRAQMLTEMAKMSLDD
HCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
GLVMQIHPGSHRNHNVGLLNSHGRDKGADIPMRTEYVDALKPLLTRLGNDPRLSIILFTL
CEEEEECCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEE
DETTYSRELAPLAGHYPVLKLGPSWWFHDSPEGMMRFREQVTETAGFYNTVGFNDDTRAF
CCCHHHHHHCHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCEE
LSIPARHDVARRVDSAFLARMVAEHRMDLVEAEELIVDLTYNLPKKAYKLDQRPDWARPA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCHHHHHCCCCCCCCCCC
TLRAAAE
CHHCCCC
>Mature Secondary Structure 
ARPLSFHEDRLFPSDPATRSYARGLYALVKDLPIISPHGHTDPSWFATNAPFQDATDLL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCEE
LAPDHYLFRMLYSQGVSLDALKVRSKAGVPDTDPREAWRVFASHFYLFRGTPSWVWLNHV
ECCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHEEEEECCCCHHHHHHH
FSQVFGFTEFLEASNADDYFDRITAALATDAFRPRALFDRFNIETLATTEGPHESLQHHA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCCCHHHHHHHHH
AIRESGWGGHVITAYRPDAVIDFEDERSPRAFERFAETSGQDVYSWKSYLEAHRLRRQAF
HHHCCCCCCCEEEEECCCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IDAGATSSDHGHPTAATADLSDVEAEALFNSLVKGDVTPEKAELFRAQMLTEMAKMSLDD
HCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
GLVMQIHPGSHRNHNVGLLNSHGRDKGADIPMRTEYVDALKPLLTRLGNDPRLSIILFTL
CEEEEECCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEE
DETTYSRELAPLAGHYPVLKLGPSWWFHDSPEGMMRFREQVTETAGFYNTVGFNDDTRAF
CCCHHHHHHCHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCEE
LSIPARHDVARRVDSAFLARMVAEHRMDLVEAEELIVDLTYNLPKKAYKLDQRPDWARPA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCHHHHHCCCCCCCCCCC
TLRAAAE
CHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA